Heterozygosity for the factor V Leiden (G1691A) mutation predisposes renal transplant recipients to thrombotic complications and graft loss

Transplantation

Volumn 72, Issue 3, 2001, Pages 549-550

  Wüthrich, Rudolf P ^a,b   Cicvara Muzar, Snjezana ^a   Booy, Christa ^a   Maly, Friedrich E ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b CANTONAL HOSPITAL ST GALLEN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; CARDIOLIPIN ANTIBODY; PHOSPHOLIPID ANTIBODY;

ADULT; ARTICLE; GENE MUTATION; GENETIC PREDISPOSITION; GRAFT REJECTION; HETEROZYGOSITY; HUMAN; INCIDENCE; KIDNEY ALLOGRAFT; KIDNEY TRANSPLANTATION; LUNG EMBOLISM; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; PROTEIN S DEFICIENCY; THROMBOSIS; VEIN THROMBOSIS;

EID: 0035881368     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200108150-00037     Document Type: Article

References (10)

1. Mutation in blood coagulation factor V associated with resistance to activated protein C
2. Molecular diagnosis of inherited bleeding disorders and thrombophilia
3. Thrombophilia
4. Epidemiology of factor V Leiden: Clinical implications
5. The factor V Leiden (R506Q) mutation and risk of thrombosis in renal transplant recipients
6. Acute renal artery and vein thrombosis after renal transplant, associated with a short partial thromboplastin time and factor V Leiden mutation
7. High rate of acute rejections in renal allograft recipients with thrombophilic risk factors
8. Factor V R506Q mutation (activated protein C resistance) is an additional risk factor for early renal graft loss associated with acute vascular rejection
9. Early loss of renal transplants in patients with thrombophilia
10. Genetic predisposition to thrombosis in renal transplant recipients: The factor V Q506 (Leiden) allele