Accumulation of flavonoids in an ntra ntrb mutant leads to tolerance to UV-C

Molecular Plant

Volumn 2, Issue 2, 2009, Pages 249-258

  Bashandy, Talaat ^a   Taconnat, Ludivine ^b   Renou, Jean Pierre ^b   Meyer, Yves ^a   Reichheld, Jean Philippe ^a  

^a UNIVERSITÉ DE PERPIGNAN   (France)

^b INSTITUTE OF PLANT SCIENCES PARIS SACLAY IPS2   (France)

Author keywords

Abiotic environmental stress; Arabidopsis; Gene expression; Oxidative and photo oxidative stress; Secondary metabolism phenylpropanoids and phenolics

Indexed keywords

ARABIDOPSIS;

ARABIDOPSIS PROTEIN; FLAVONOID; NTRA PROTEIN, ARABIDOPSIS; NTRB PROTEIN, ARABIDOPSIS; THIOREDOXIN REDUCTASE;

ARABIDOPSIS; GENETICS; METABOLISM; MUTATION; OXIDATIVE STRESS; RADIATION DOSE; RADIATION RESPONSE; ULTRAVIOLET RADIATION;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; FLAVONOIDS; MUTATION; OXIDATIVE STRESS; RADIATION TOLERANCE; THIOREDOXIN-DISULFIDE REDUCTASE; ULTRAVIOLET RAYS;

EID: 65249158581     PISSN: 16742052     EISSN: 17529867     Source Type: Journal    
DOI: 10.1093/mp/ssn065     Document Type: Article

References (48)

1. Albert, S., Deiseny, M., and Devic, M. (1997). BANYULS, a novel negative regulator of flavonoid biosynthesis in the Arabidopsis seed coat. Plant J. 11, 289-299.
2. Alfenito, M.R., Souer, E., Goodman, CD., Buell, R., Mol, J., Koes, R., and Walbot, V. (1998). Functional complementation of anthocyanin sequestration in the vacuole by widely divergent glutathione S-transferases. Plant Cell. 10, 1135-1149.
3. Alonso, J.M., et al. (2003). Genome-wide insertional mutagenesis of Arabidopsis thaliana. Science. 301, 653-657.
4. Besseau, S., Hoffmann, L, Goeffroy, P., Lapierre, C., Pollet, B., and Legrand, M. (2007). Flavonoid accumulation in Arabidopsis repressed in lignin synthesis affects auxin transport and plant growth. Plant Cell. 19, 148-162.
5. Bieza, K.,and Lois, R. (2001). An Arabidopsis mutanttolerantto lethal ultraviolet-B levels shows constitutively elevated accumulation of f lavonoids and other phenolics. Plant Physiol. 126, 1105-1115.
6. Bironaite, D., Anusevicius, Z., Jacquot, J.P., and Cenas, N. (1998). Interaction of quinones with Arabidopsis thaliana thioredoxin reductase. Biochim. Biophys. Acta. 1383, 82-92.
7. Böhm, H., Boeing, H., Hempel, J., Raab, B., and Kroke, A. (1998). Flavonols, flavone and anthocyanins as natural antioxidants of food and their possible role in the prevention of chronic diseases. Z. Ernahrungswiss. 37, 147-163.
8. Borevitz, J.O., Xia, Y., Blount, J., Dixon, R.A., and Lamb, C. (2000). Activation tagging identifies a conserved MYB regulator of phenylpropanoid biosynthesis. Plant Cell. 12, 2383-2394.
9. Boyes, D.C., Zayed, A.M., Ascenzi, R., McCaskill, A.J., Hoffman, N.E., Davis, K.R., and Gorlach, J. (2001). Growth stage-based phenotypic analysis of arabidopsis: a model for high throughput functional genomics in plants. Plant Cell. 13, 1499-1510.
10. Carmel-Harel, O., and Storz, G. (2000). Roles of the glutathione- and thioredoxin-dependent reduction systems in the Escherichia coli and saccharomyces cerevisiae responses to oxidative stress. Annu. Rev. Microbiol. 54, 439-461.
11. Crowe, M.L., et al. (2003). CATMA: a complete Arabidopsis GST database. Nucleic Acids Res. 31, 156-158.
12. Dixon, R.A., and Paiva, N.L. (1995). Stress-induced phenylpropanoid metabolism. Plant Cell. 7, 1085-1097.
13. Feinbaum, R.L., and Ausubel, F.M. (1988). Transcriptional regulation of the Arabidopsis thaliana chalcone synthase gene. Mol. Cell. Biol. 8, 1985-1992.
14. Filkowski, J., Kovalchuk, O., and Kovalchuk, I. (2004). Genome stability of vtc1, tt4, and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. Plant J. 38, 60-69.
15. Foyer, C.H., and Noctor, G. (2005). Redox homeostasis and antioxidant signaling: a metabolic interface between stress perception and physiological responses. Plant Cell. 17, 1866-1875.
16. Ge, Y., Dudoit, S., and Speed, T.P. (2003). Resampling-based multiple testing for microarray data analysis. Test. 12, 1-77.
17. Gonzalez, A., Zhao, M., Leavitt, J.M., and Lloyd, A.M. (2008). Regulation of the anthocyanin biosynthetic pathway by the TTG1/ bHLH/Myb transcriptional complex in Arabidopsis seedlings. Plant J. 53, 814-827.
18. Gross, J. (1991). Pigments in vegetables: chlorophylls and carotenoids. In AVI Book, Gross, J., ed (New York: Van Nostrand Reinold Publishing), p. 303.
19. Halliwell, B., and Gutteridge, J.M.C. (1989). Free Radicals in Biology and Medicine (Oxford: Clarendon Press).
20. Hilson, P., et al. (2004). Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. Genome Res. 14, 2176-2189.
21. Holmgren, A. (1985).Thioredoxin. Annu. Rev. Biochem. 54, 237-271.
22. Imlay, J.A., and Linn, S. (1988). DNA damage and oxygen radical toxicity. Science. 240, 1302-1309.
23. Iqbal, A., Yabuta, Y., Takeda, T., Nakano, Y., and Shigeoka, S. (2006). Hydroperoxide reduction by thioredoxin-specific glutathione peroxidase isoenzymes of Arabidopsis thaliana. FEBS J. 273, 5589-5597.
24. Jansen, M.A.K., Gaba, V., and Greeberg, B.M. (1998). Higher plant and UV-B radiation: balancing damage, repair and acclimation. Trends Plant Sci. 3, 131-135.
25. Jin, H., Cominelli, E., Bailey, P., Parr, A., Mehrtens, F., Jones, J.D., Tonelli, C., Weisshaar, B., and Martin, C. (2000). Transcriptional repression by AtMYB4 controls production of UV-protecting sunscreens in Arabidopsis. EMBO J. 19, 6150-6161.
26. Laloi, C., Mestres-Ortega, D., Marco, Y., Meyer, Y., and Reichheld, J.P. (2004). TheArabidopsis cytosolicthioredoxin h5 gene induction by oxidative stress and its W-box-mediated response to pathogen elicitor. Plant Physiol. 134, 1006-1016. Epub 2004 Feb 1019.
27. Li, J., Ou-Lee, T.M., Raba, R., Amundson, R.G., and Last, R.L. (1993). Arabidopsis f lavonoid mutants are hypersensitive to UV-B irradiation. Plant Cell. 5, 171-179.
28. Lois, R. (1994). Accumulation of UV-absorbing flavonoids induced by UV-B radiation in Arabidopsis thaliana. Planta. 194, 498-503.
29. Lois, R., and Buchanan, B.B. (1994). Severe sensitivity to ultraviolet radiation in an Arabidopsis mutant deficient in flavonoid accumulation. Planta. 194, 504-509.
30. Lurin, C., et al. (2004). Genome wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis. Plant Cell. 16, 2089-2103.
31. Meyer, Y., Riondet, C., Constans, L., Abdelgawwad, M.R., Reichheld, J.R, and Vignols, F. (2006). Evolution of redoxin genes in the green lineage. Photosynth. Res. 89, 1-14.
32. Miskiniene, V., Sarlauskas, J., Jacquot, J.P., and Cenas, N. (1998). Nitroreductase reactions of Arabidopsis thaliana thioredoxin reductase. Biochim. Biophys. Acta. 1366, 275-283.
33. Mittler, R. (2002). Oxidative stress, antioxidants and stress tolerance. Trends Plant Sci. 7, 405-410.
34. Navrot, N., Collin, V., Gualberto, J., Gelhaye, E., Hirasawa, M., Rey, P., Knaff, D.B., Issakidis, E., Jacquot J.-P., and Rouhier, N. (2006). Plant glutathione peroxidases are functional peroxiredoxins distributed in several subcellular compartments and regulated during biotic and abiotic stresses. Plant Physiol. 142, 1364-1379.
35. Nordberg, J., and Arner, E.S. (2001). Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 31, 1287-1312.
36. Ormrod, D.P., Landry, L.G., and Conklin, P.L. (1995). Shortterm UVBradiation and ozone exposure effects on aromatic secondar-ymetabolite accumulation and shoot growth of flavonoid-deficient Arabidopsis mutants. Physiol. Plant. 93, 602-610.
37. Reichheld, J.P., Khafif, M., Riondet, C., Droux, M., Bonnard, G., and Meyer, Y. (2007). Inactivation of thioredoxin reductases reveals a complex interplay between thioredoxin and glutathione pathways in Arabidopsis development. Plant Cell. 19, 1851-1865.
38. Reichheld, J.P., Mestres-Ortega, D., Laloi, C., and Meyer, Y. (2002). The multigenic family of thioredoxin h in Arabidopsis thaliana: specific expression and stress response. Plant Physiol. Biochem. 40, 685-690.
39. Reichheld, J.P., Meyer, E., Khafif, M., Bonnard, G., and Meyer, Y. (2005). AtNTRB is the major mitochondrial thioredoxin reductase in Arabidopsis thaliana. FEBS Lett. 579, 337-342.
40. Schürmann, P., and Jacquot J.P. (2000). Plant thioredoxin systems revisited. Annu. Rev. Plant Physiol. Plant Mol. Biol. 51, 371-400.
41. Shirley, B.W., Kubasek, W.L., Storz, G., Bruggemann, E., Koornneef, M., Ausubel, F.M., and Goodman, H.M. (1995). Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis. Plant J. 8, 659-671.
42. Solovchenko, A., and Schmitz-Eiberger, M. (2003). Significance of skin flavonoids for UV-B-protection in apple fruits. J. Exp. Bot. 54, 1977-1984.
43. Stracke, R., Ishihara, H., Huep, G., Barsch, A., Mehrtens, F., Niehaus, K., and Weisshaar, B. (2007). Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling. Plant J. 50, 660-677.
44. Stracke, R., Werber, M., and Weisshaar, B. (2001). The R2R3-MYB gene family in Arabidopsis thaliana. Curr. Opin. Plant Biol. 4, 447-456.
45. Tanaka, A., Sakamoto, A., Ishigaki, Y., Nikaido, O., Sun, G., Hase, Y., Shikazono, N., Tano, S., and Watanabe, H. (2002). An ultraviolet-B-resistant mutant with enhanced DNA repair in Arabidopsis. Plant Physiol. 129, 64-71.
46. Van Breusegem, F., Bailey-Serres, J., and Mittler, R. (2008). Unraveling the tapestry of networks involving reactive oxygen species in plants. Plant Physiol. 147, 978-984.
47. Winkel-Shirley, B. (2002). Biosynthesis of flavonoids and effects of stress. Curr. Opin. Plant Biol. 5, 218-223.
48. Zhao, J., Zhang, W., Zhao, Y., Gong, X., Guo, L., Zhu, G., Wang, X., Gong, Z., Schumaker, K.S., and Guo, Y. (2007). SAD2, an importin -like protein, is required for UV-B response in Arabidopsis by mediating MYB4 nuclear trafficking. Plant Cell. 19, 3805-3818.