The 3′-to-5′ exoribonuclease (encoded by HP1248) of Helicobacter pylori regulates motility and apoptosis-inducing Genes

Journal of Bacteriology

Volumn 191, Issue 8, 2009, Pages 2691-2702

  Tsao, Ming Yang ^a   Lin, Tzu Lung ^a   Hsieh, Pei Fang ^a,b   Wang, Jin Town ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

3' TO 5' EXORIBONUCLEASE; APOPTOSIS INDUCING FACTOR; CAGA PROTEIN; CHEY PROTEIN; EXORIBONUCLEASE; MESSENGER RNA; RIBONUCLEASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; BACTERIAL PROTEIN;

APOPTOSIS; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CELL MOTILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE CONTROL; GENE DELETION; GENE SEQUENCE; GENETIC STABILITY; HELICOBACTER PYLORI; MICROARRAY ANALYSIS; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHIGELLA; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DNA MICROARRAY; ENZYMOLOGY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION; GENETICS; LOCOMOTION; MACROPHAGE; MICROBIOLOGY; MOUSE; PHYSIOLOGY;

ESCHERICHIA COLI; HELICOBACTER PYLORI; SHIGELLA;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; CELL LINE; CLONING, MOLECULAR; ESCHERICHIA COLI; EXORIBONUCLEASES; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; HELICOBACTER PYLORI; LOCOMOTION; MACROPHAGES; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; VIRULENCE FACTORS;

EID: 65249138666     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01182-08     Document Type: Article

References (46)

1. Alamuri, P., and R. J. Maier. 2004. Methionine sulphoxide reductase is an important antioxidant enzyme in the gastric pathogen Helicobacter pylori. Mol. Microbiol. 53:1397-1406.
2. Amblar, M., and C. M. Arraiano. 2005. A single mutation in Escherichia coli ribonuclease II inactivates the enzyme without affecting RNA binding. FEBS J. 272:363-374.
3. Andrade, J. M., F. Cairrao, and C. M. Arraiano. 2006. RNase R affects gene expression in stationary phase: regulation of ompA. Mol. Microbiol. 60:219-228.
4. Ang, S., C. Z. Lee, K. Peck, M. Sindici, U. Matrubutham, M. A. Gleeson, and J. T. Wang. 2001. Acid-induced gene expression in Helicobacter pylori: study in genomic scale by microarray. Infect. Immun. 69:1679-1686.
5. Basak, C., S. K. Pathak, A. Bhattacharyya, S. Pathak, J. Basu, and M. Kundu. 2005. The secreted peptidyl prolyl cis,trans-isomerase HP0175 of Helicobacter pylori induces apoptosis of gastric epithelial cells in a TLR4- and apoptosis signal-regulating kinase 1-dependent manner. J. Immunol. 174: 5672-5680.
6. Blaser, M. J. 1992. Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation. Gastroenterology 102:720-727.
7. Brahmachary, P., M. G. Dashti, J. W. Olson, and T. R. Hoover. 2004. Helicobacter pylori FlgR is an enhancer-independent activator of sigma54- RNA polymerase holoenzyme. J. Bacteriol. 186:4535-4542.
8. Cairrao, F., A. Cruz, H. Mori, and C. M. Arraiano. 2003. Cold shock induction of RNase R and its role in the maturation of the quality control mediator SsrA/tmRNA. Mol. Microbiol. 50:1349-1360.
9. Censini, S., C. Lange, Z. Xiang, J. E. Crabtree, P. Ghiara, M. Borodovsky, R. Rappuoli, and A. Covacci. 1996. cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc. Natl. Acad. Sci. USA 93:14648-14653.
10. Chang, K. C., S. W. Ho, J. C. Yang, and J. T. Wang. 1997. Isolation of a genetic locus associated with metronidazole resistance in Helicobacterpylori. Biochem. Biophys. Res. Commun. 236:785-788.
11. Cheng, Z. F., and M. P. Deutscher. 2005. An important role for RNase R in mRNA decay. Mol. Cell 17:313-318.
12. Cheng, Z. F., Y. Zuo, Z. Li, K. E. Rudd, and M. P. Deutscher. 1998. The vacB gene required for virulence in Shigella flexneri and Escherichia coli encodes the exoribonuclease RNase R. J. Biol. Chem. 273:14077-14080.
13. Chevalier, C., J. M. Thiberge, R. L. Ferrero, and A. Labigne. 1999. Essential role of Helicobacter pylori gamma-glutamyltranspeptidase for the colonization of the gastric mucosa of mice. Mol. Microbiol. 31:1359-1372.
14. Covacci, A., J. L. Telford, G. Del Giudice, J. Parsonnet, and R. Rappuoli. 1999. Helicobacterpylori virulence and genetic geography. Science 284:1328-1333.
15. Eaton, K. A., D. R. Morgan, and S. Krakowka. 1992. Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori. J. Med. Microbiol. 37:123-127.
16. Fan, X. G., D. Kelleher, X. J. Fan, H. X. Xia, and P. W. Keeling. 1996. Helicobacter pylori increases proliferation of gastric epithelial cells. Gut 38: 19-22.
17. Gobert, A. P., Y. Cheng, J. Y. Wang, J. L. Boucher, R. K. Iyer, S. D. Cederbaum, R. A. Casero, Jr., J. C. Newton, and K. T. Wilson. 2002. Helicobacter pylori induces macrophage apoptosis by activation of arginase II. J. Immunol. 168:4692-4700.
18. Heuermann, D., and R. Haas. 1998. A stable shuttle vector system for efficient genetic complementation of Helicobacter pylori strains by transformation and conjugation. Mol. Gen. Genet. 257:519-528.
19. Hsieh, P. F., J. C. Yang, J. T. Lin, and J. T. Wang. 1998. Molecular mechanisms of clarithromycin resistance in Helicobacter pylori. J. Formos. Med. Assoc. 97:445-452.
20. Karzai, A. W., and R. T. Sauer. 2001. Protein factors associated with the SsrA. SmpB tagging and ribosome rescue complex. Proc. Natl. Acad. Sci. USA 98:3040-3044.
21. Kasai, T., R. S. Gupta, and D. Schlessinger. 1977. Exoribonucleases in wild type Escherichia coli and RNase II-deficient mutants. J. Biol. Chem. 252: 8950-8956.
22. Khemici, V., and A. J. Carpousis. 2004. The RNA degradosome and poly(A) polymerase of Escherichia coli are required in vivo for the degradation of small mRNA decay intermediates containing REP-stabilizers. Mol. Microbiol. 51:777-790.
23. Kim, K. M., S. G. Lee, M. G. Park, J. Y. Song, H. L. Kang, W. K. Lee, M. J. Cho, K. H. Rhee, H. S. Youn, and S. C. Baik. 2007. Gamma-glutamyl-transpeptidase of Helicobacter pylori induces mitochondria-mediated apop- tosis in AGS cells. Biochem. Biophys. Res. Commun. 355:562-567.
24. Kostrzynska, M., J. D. Betts, J. W. Austin, and T. J. Trust. 1991. Identification, characterization, and spatial localization of two flagellin species in Helicobacter pylori flagella. J. Bacteriol. 173:937-946.
25. Le'Negrate, G., V. Ricci, V. Hofman, B. Mograbi, P. Hofman, and B. Rossi. 2001. Epithelial intestinal cell apoptosis induced by Helicobacter pylori depends on expression of the cag pathogenicity island phenotype. Infect. Immun. 69:5001-5009.
26. Li, Z., S. Reimers, S. Pandit, and M. P. Deutscher. 2002. RNA quality control: degradation of defective transfer RNA. EMBO J. 21:1132-1138.
27. Marshall, B. J., and J. R. Warren. 1984. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet i:1311-1315.
28. Mathy, N., L. Benard, O. Pellegrini, R. Daou, T. Wen, and C. Condon. 2007. 5′-to-3′ exoribonuclease activity in bacteria: role of RNase J1 in rRNA maturation and 5' stability of mRNA. Cell 129:681-692.
29. McGee, D. J., M. L. Langford, E. L. Watson, J. E. Carter, Y. T. Chen, and K. M. Ottemann. 2005. Colonization and inflammation deficiencies in Mongolian gerbils infected by Helicobacter pylori chemotaxis mutants. Infect. Immun. 73:1820-1827.
30. Menaker, R. J., P. J. Ceponis, and N. L. Jones. 2004. Helicobacter pylori induces apoptosis of macrophages in association with alterations in the mitochondrial pathway. Infect. Immun. 72:2889-2898.
31. Moss, S. F. 1998. Helicobacter pylori and apoptosis. Yale J. Biol. Med. 71:53-61.
32. Nomura, A., G. N. Stemmermann, P. H. Chyou, I. Kato, G. I. Perez-Perez, and M. J. Blaser. 1991. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N. Engl. J. Med. 325:1132-1136.
33. Ottemann, K. M., and A. C. Lowenthal. 2002. Helicobacter pylori uses mo- tility for initial colonization and to attain robust infection. Infect. Immun. 70:1984-1990.
34. Oussenko, I. A., R. Sanchez, and D. H. Bechhofer. 2002. Bacillus subtilis YhaM, a member of a new family of 3′-to-5′ exonucleases in gram-positive bacteria. J. Bacteriol. 184:6250-6259.
35. Parsonnet, J., G. D. Friedman, D. P. Vandersteen, Y. Chang, J. H. Vogelman, N. Orentreich, and R. K. Sibley. 1991. Helicobacterpylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 325:1127-1131.
36. Rader, B. A., S. R. Campagna, M. F. Semmelhack, B. L. Bassler, and K. Guillemin. 2007. The quorum-sensing molecule autoinducer 2 regulates motility and flagellar morphogenesis in Helicobacter pylori. J. Bacteriol. 189: 6109-6117.
37. Schmitz, A., C. Josenhans, and S. Suerbaum. 1997. Cloning and characterization of the Helicobacter pylori flbA gene, which codes for a membrane protein involved in coordinated expression of flagellar genes. J. Bacteriol. 179:987-997.
38. Suerbaum, S., C. Josenhans, and A. Labigne. 1993. Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flaB flagellin genes and construction of H. pylori flaA- and flaB-negative mutants by electroporation-mediated allelic exchange. J. Bacteriol. 175:3278-3288.
39. Tiwari, S., U. Ghoshal, U. C. Ghoshal, S. Dhingra, R. Pandey, M. Singh, A. Ayyagari, and S. Naik. 2005. Helicobacterpylori -induced apoptosis in patho- genesis of gastric carcinoma. Indian J. Gastroenterol. 24:193-196.
40. Tobe, T., C. Sasakawa, N. Okada, Y. Honma, and M. Yoshikawa. 1992. vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri. J. Bacteriol. 174:6359-6367.
41. Williams, S. M., Y. T. Chen, T. Andermann, J. E. Carter, D. J. McGee, and K. M. Ottemann. 2007. Helicobacter pylori chemotaxis modulates inflammation and gastric-epithelium interactions in infected mice. Infect. Immun. 75:3747-3757.
42. Wotherspoon, A. C., C. Doglioni, T. C. Diss, L. Pan, A. Moschini, M. de Boni, and P. G. Isaacson. 1993. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 342:575-577.
43. Xu, Q., and M. J. Blaser. 2001. Promoters of the CATG-specific methyl-transferase gene hpyIM differ between iceA1 and iceA2 Helicobacter pylori strains. J. Bacteriol. 183:3875-3884.
44. Yeh, Y. C., T. L. Lin, K. C. Chang, and J. T. Wang. 2003. Characterization of a ComE3 homologue essential for DNA transformation in Helicobacter pylori. Infect. Immun. 71:5427-5431.
45. Zhu, Y., C. Wang, J. Huang, Z. Ge, Q. Dong, X. Zhong, Y. Su, and S. Zheng. 2007. The Helicobacter pylori virulence factor CagA promotes Erk1/2-medi- ated Bad phosphorylation in lymphocytes: a mechanism of CagA-inhibited lymphocyte apoptosis. Cell Microbiol. 9:952-961.
46. Zukowski, M. M., D. F. Gaffney, D. Speck, M. Kauffmann, A. Findeli, A. Wisecup, and J. P. Lecocq. 1983. Chromogenic identification of genetic regulatory signals in Bacillus subtilis based on expression of a cloned Pseudomonas gene. Proc. Natl. Acad. Sci. USA 80:1101-1105.