A mathematical model for the detection mechanism of DNA double-strand breaks depending on autophosphorylation of ATM

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Mouri, Kazunari ^a   Nacher, Jose C ^b   Akutsu, Tatsuya ^a  

^a KYOTO UNIVERSITY   (Japan)

^b FUTURE UNIVERSITY HAKODATE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; PROTEIN P53; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

ALGORITHM; ARTICLE; AUTOPHOSPHORYLATION; AUTOREGULATION; BIOSENSOR; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; MATHEMATICAL MODEL; NEGATIVE FEEDBACK; SIMULATION; STEADY STATE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; STATISTICS; THEORETICAL MODEL;

ALGORITHMS; CELL CYCLE PROTEINS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; MODELS, THEORETICAL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STOCHASTIC PROCESSES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 65249133930     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005131     Document Type: Article

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