Lineage-negative bone marrow cells protect against chronic renal failure

Stem Cells

Volumn 27, Issue 3, 2009, Pages 682-692

  Alexandre, Cristianne Silva ^a   Volpini, Rildo Aparecido ^a   Shimizu, Maria Heloísa ^a   Sanches, Talita Rojas ^a   Semedo, Patricia ^b   Jura, Vera Lúcia Di ^a   Câmara, Niels Olsen ^a,b   Seguro, Antonio Carlos ^a   Andrade, Lúcia ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Chronic proteinuria; Fibrosis pathology; Hematopoietic stem cells; Kidney failure; Nephrectomy; Proliferating cell nuclear antigen

Indexed keywords

CELL NUCLEUS ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P21; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CELL INFILTRATION; CELL LINEAGE; CELL PROLIFERATION; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; GLOMERULOSCLEROSIS; INULIN CLEARANCE; KIDNEY FUNCTION; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEINURIA; RAT;

ANIMALS; ANTIGENS, CD29; ANTIGENS, CD31; ANTIGENS, CD34; ANTIGENS, CD44; ANTIGENS, CD45; ANTIGENS, THY-1; BLOTTING, WESTERN; BONE MARROW CELLS; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINE CXCL12; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; KIDNEY; KIDNEY FAILURE, CHRONIC; NEPHRECTOMY; RATS; RATS, INBRED F344; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

RATTUS;

EID: 65249127492     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0496     Document Type: Article

References (44)

1. Sociedade Brasileira de Nefrologia. Annual census, 2006 [PowerPoint presentation; 19 slides]. Available at http://www.sbn.org.br/Censo/2006/ censoSBN2006.ppt. Accessed May 18, 2008.
2. Hishikawa K, Fujita T. Stem cells and kidney Disease. Hypertens Res 2006;29:745-749.
3. Mollura DJ, Hare JM, Rabb H. Stem-cell therapy for renal diseases. Am J Kidney Dis 2003;42:891-905.
4. Rosenthal N. Prometheus's vulture and the stem-cell promise. N Engl J Med 2003;349:267-274.
5. Oliver JA, Maarouf O, Cheema FH et al. The renal papilla is a niche for adult kidney stem cells. J Am Soc Nephrol 2006;17:S123-S126.
6. Bussolati B, Bruno S, Grange C et al. Isolation of renal progenitor cells from adult human kidney. Am J Pathol 2005;166:545-555.
7. Kitamura S, Yamasaki Y, Kinomura M et al. Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney. FASEB J 2005;19:1789-1797.
8. Dalakas E, Newsome PN, Harrison DJ, Plevris JN. Hematopoietic stem cell trafficking in liver injury. FASEB J 2005;19:1225-1231.
9. Gupta S, Verfaillie C, Chmielewski D et al. A role for extrarenal cells in the regeneration following acute renal failure. Kidney Int 2002;62: 1285-1290.
10. Lin F, Cordes K, Li L et al. Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 2003;14:1188-1199.
11. Morigi M, Imberti B, Zoja C et al. Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol 2004;15:1794-1804.
12. Li B, Morioka T, Uchiyama M et al. Bone marrow cell infusion ameliorates progressive glomerulosclerosis in an experimental rat model. Kidney Int 2006;69:323-330.
13. Sugimoto H, Mundel TM, Sund M et al. Bone marrow derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proc Natl Acad Sci USA 2006;103:7321-7326.
14. Ninichuk V, Gross O, Sereger S et al. Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice. Kidney Int 2006;70: 121-129.
15. Zerbini G, Piemont L, Maestroni A et al. Stem cells and the kidney: a new therapeutic tool?J Am Soc Nephrol 2006;17:S123-S126.
16. Volpini RA, Costa RS, Silva CG et al. Inhibition of nuclear factor-κB activation attenuates tubulointerstitial nephritis induced by gentamicin. Nephron Physiol 2004;98:p97-p106.
17. Lavaud S, Michel O, Sassy-Prigent C et al. Early influx of glomerular macrophages precedes glomerulosclerosis in the obese Zucker rat model. J Am Soc Nephrol 1996;12:2604-2615.
18. Wang Y, Chen J, Chen L et al. Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein. J Am Soc Nephrol 1997;8:1537-1545.
19. Schrijvers BF, Flyvbjerg A, Tilton RG et al. Pathophysiological role of vascular endothelial growth factor in the remnant kidney. Nephron Exp Nephrol 2005;101:e9-e15.
20. Griffin SV, Olivier JP, Pippin JW et al. Cyclin I protects podocytes from apoptosis. J Biol Chem 2006;281:28048-28057.
21. Kobayashi S, Hishida A. Effects of a calcium antagonist, manidipine, on progressive renal injury associated with mild hypertension in remnant kidneys. J Lab Clin Med 1995;125:572-580.
22. Meyer TW, Anderson S, Rennke HG et al. Converting enzyme inhibitor therapy limits progressive glomerular injury in rats with renal insufficiency. Am J Med 1985;79:31-36.
23. Griffin KA, Abu-Amarah I, Picken M et al. Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent. Hypertension 2003;41:201-206.
24. Klahr S, Schreiner G, Ichikawa I. The progression of renal disease. N Engl J Med 1988;318:1657-1666.
25. Romero F, Rodriguez-Iturbe B, Parra G et al. Mycophenolate mofetil prevents the progressive renal failure induced by 5/6 renal ablation in rats. Kidney Int 1999;55:945-955.
26. Stokman G, Leemans JC, Claessen N et al. Hematopoietic stem cell mobilization therapy accelerates recovery of renal function independent of stem cell contribution. J Am Soc Nephrol 2005;16:1684-1692.
27. Schwarting S, Litwak S, Hao W et al. Hematopoietic stem cells reduce postischemic inflammation and ameliorate ischemic brain injury. Stroke 2008;39:2867-2875.
28. Ruiz-Ortega M, Ruperez M, Lorenzo O et al. Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney. Kidney Int 2002;62(suppl 82):S12-S22.
29. Mu W, Ouyang X, Agarwal A et al. IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol 2005;16:3651-3660.
30. Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815-1822.
31. - Hematopoietic stem cells: current concepts and controversies. Stem Cells 2003;21:15-20.
32. Sonoda Y. Immunophenotype and functional characteristics of human primitive CD34-negative hematopoietic stem cells: the significance of the intra-bone marrow injection. J Autoimmun 2008;30:136-144.
33. Tögel F, Isaac J, Hu Z et al. Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury. Kidney Int 2005;67:1772-1784.
34. Darash-Yahana M, Pikarsky E, Abramovitch R et al. Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J 2004;18:1240-1242.
35. Terzi G, Ticozzi C, Burtin M et al. Subtotal but not unilateral nephrectomy induces hyperplasia and protooncogene expression. Am J Physiol 1995;268:F793-F801.
36. Floege J, Burns MW, Alpers CE et al. Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int 1992;41:297-309.
37. Yoshida Y, Fogo A, Ichikawa I. Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis. Kidney Int 1989;35:654-660.
38. Dotto GP. p21(WAF1/Cip1): more than a break to the cell cycle?Biochim Biophys Acta 2000;1471:M43-M56.
39. Shankland SJ, Eitner F, Hudkins KL et al. Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation. Kidney Int 2000;58:674-683.
40. Zhang H, Hannon GJ, Beach D. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 1994;8:1750-1758.
41. LaBaer J, Garrett MD, Stevenson LF et al. New functional activities for the p21 family of CDK inhibitors. Genes Dev 1997;11: 847-862.
42. Law M, Forrester E, Chytil A et al. Rapamycin disrupts cyclin/cyclin-dependent kinase/p21/proliferating cell nuclear antigen complexes and cyclin D1 reverses rapamycin action by stabilizing these complexes. Cancer Res 2006;66:1070-1080.
43. Chen IT, Akamatsu M, Smith ML et al. Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction. Oncogene 1996;12:595-607.
44. Olive M, Mellad JA, Beltran LE et al. p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice. J Clin Invest 2008;118:2050-2061.