Olfactory psychometric functions for homologous 2-ketones

Behavioural Brain Research

Volumn 201, Issue 1, 2009, Pages 207-215

  Cometto Muñiz, J Enrique ^a   Abraham, Michael H ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Concentration detection odor functions; Homologous 2 ketones; Odor detection thresholds; Olfactory structure activity relationships

Indexed keywords

2 HEPTANONE; 2 NONANONE; 2 PENTANONE; ACETONE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; OLFACTOMETER; PRIORITY JOURNAL; PSYCHOMETRY; SMELLING;

ACETONE; ADOLESCENT; ADULT; FEMALE; HUMANS; KETONES; LOGISTIC MODELS; MALE; ODORS; OLFACTORY PERCEPTION; PENTANONES; PHYSICAL STIMULATION; PSYCHOMETRICS; SENSORY THRESHOLDS; YOUNG ADULT;

EID: 65249120907     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2009.02.014     Document Type: Article

References (42)

1. Abraham M.H., Gola J.M.R., Cometto-Muñiz J.E., and Cain W.S. The correlation and prediction of VOC thresholds for nasal pungency, eye irritation and odour in humans. Indoor Built Environ 10 (2001) 252-257
2. Abraham M.H., Gola J.M.R., Cometto-Muñiz J.E., and Cain W.S. A model for odour thresholds. Chem Senses 27 (2002) 95-104
3. Abraham M.H., Ibrahim A., and Acree W.E. Partition of compounds from gas to water and from gas to physiological saline at 310 K: linear free energy relationships. Fluid Phase Equilib 251 (2007) 93-109
4. Abraham M.H., Sánchez-Moreno R., Cometto-Muñiz J.E., and Cain W.S. A quantitative structure-activity analysis on the relative sensitivity of the olfactory and the nasal trigeminal chemosensory systems. Chem Senses 32 (2007) 711-719
5. Brody T.M. Concentration-response relationships. In: Minneman K.P., Brody T.M., and Larner J. (Eds). Human pharmacology: molecular to clinical. (1994), Mosby-Year Book, St. Louis 25-32
6. Brown K.S., Maclean C.M., and Robinette R.R. The distribution of the sensitivity to chemical odors in man. Hum Biol 40 (1968) 456-472
7. Cain W.S. Differential sensitivity for smell: "noise" at the nose. Science 195 (1977) 796-798
8. Cain W.S. Testing olfaction in a clinical setting. Ear Nose Throat J 68 (1989) 316-328
9. Cain W.S., Schmidt R., and Wolkoff P. Olfactory detection of ozone and d-limonene: reactants in indoor spaces. Indoor Air 17 (2007) 337-347
10. Cometto-Muñiz J.E., and Cain W.S. Efficacy of volatile organic compounds in evoking nasal pungency and odor. Arch Environ Health 48 (1993) 309-314
11. Cometto-Muñiz J.E. Physicochemical basis for odor and irritation potency of VOCs. In: Spengler J.D., Samet J., and McCarthy J.F. (Eds). Indoor Air Quality Handbook (2001), McGraw-Hill, New York 20.1-20.21
12. Cometto-Muñiz J.E., Cain W.S., and Abraham M.H. Quantification of chemical vapors in chemosensory research. Chem Senses 28 (2003) 467-477
13. Cometto-Muñiz J.E., and Abraham M.H. Human olfactory detection of homologous n-alcohols measured via concentration-response functions. Pharmacol Biochem Behav 89 (2008) 279-291
14. Cometto-Muñiz J.E., Cain W.S., Abraham M.H., and Gil-Lostes J. Concentration-detection functions for the odor of homologous n-acetate esters. Physiol Behav 95 (2008) 658-667
15. Dalton P.H., Dilks D.D., and Banton M.I. Evaluation of odor and sensory irritation thresholds for methyl isobutyl ketone in humans. Am Ind Hyg Assoc J 61 (2000) 340-350
16. Devos M., Patte F., Rouault J., Laffort P., and van Gemert L.J. Standardized human olfactory thresholds (1990), IRL Press, Oxford
17. Gaillard I., Rouquier S., Pin J.P., Mollard P., Richard S., Barnabe C., et al. A single olfactory receptor specifically binds a set of odorant molecules. Eur J Neurosci 15 (2002) 409-418
18. Gaillard I., Rouquier S., Chavanieu A., Mollard P., and Giorgi D. Amino-acid changes acquired during evolution by olfactory receptor 912-93 modify the specificity of odorant recognition. Hum Mol Genet 13 (2004) 771-780
19. Hummel P., Vaidehi N., Floriano W.B., Hall S.E., and Goddard III W.A. Test of the Binding Threshold Hypothesis for olfactory receptors: explanation of the differential binding of ketones to the mouse and human orthologs of olfactory receptor 912-93. Protein Sci 14 (2005) 703-710
20. Jones F.N. An analysis of individual differences in olfactory thresholds. Am J Psychol 70 (1957) 227-232
21. Knudsen H.N., Clausen G., and Fanger P.O. Sensory characterization of emissions from materials. Indoor Air 7 (1997) 107-115
22. Knudsen H.N., Valbjørn O., and Nielsen P.A. Determination of exposure-response relationships for emissions from building products. Indoor Air 8 (1998) 264-275
23. Lai P.C., Bahl G., Gremigni M., Matarazzo V., Clot-Faybesse O., Ronin C., et al. An olfactory receptor pseudogene whose function emerged in humans: a case study in the evolution of structure-function in GPCRs. J Struct Funct Genomics 9 (2008) 29-40
24. Laing D.G. Characterisation of human behaviour during odour perception. Perception 11 (1982) 221-230
25. Laing D.G. Natural sniffing gives optimum odour perception for humans. Perception 12 (1983) 99-117
26. Laska M., Miethe V., Rieck C., and Weindl K. Olfactory sensitivity for aliphatic ketones in squirrel monkeys and pigtail macaques. Exp Brain Res 160 (2005) 302-311
27. Macmillan N.A., and Creelman C.D. Detection theory: a user's guide (1991), Cambridge University Press, Cambridge
28. Matarazzo V., Clot-Faybesse O., Marcet B., Guiraudie-Capraz G., Atanasova B., Devauchelle G., et al. Functional characterization of two human olfactory receptors expressed in the baculovirus Sf9 insect cell system. Chem Senses 30 (2005) 195-207
29. Price N.C., Dwek R.A., Ratcliffe R.G., and Wormald M. Principles and problems in physical chemistry for biochemists (2001), Oxford University Press, Oxford
30. Punter P.H. Measurement of human olfactory thresholds for several groups of structurally related compounds. Chem Senses 7 (1983) 215-235
31. Rabin M.D., and Cain W.S. Determinants of measured olfactory sensitivity. Percept Psychophys 39 (1986) 281-286
32. Sanz G., Schlegel C., Pernollet J.C., and Briand L. Comparison of odorant specificity of two human olfactory receptors from different phylogenetic classes and evidence for antagonism. Chem Senses 30 (2005) 69-80
33. Schmidt R., and Cain W.S. How to make and measure smells-practical lessons in olfactometry. Chem Senses 28 551 (2003) A597 [abstract]
34. Snyder R. Basic concepts of the dose-response relationship. In: Rodricks J.V., and Tardiff R.G. (Eds). Assessment and management of chemical risks (1984), American Chemical Society, Washington, DC 37-55
35. Stevens J.C., Cain W.S., and Burke R.J. Variability of olfactory thresholds. Chem Senses 13 (1988) 643-653
36. Stevens J.C., and Dadarwala A.D. Variability of olfactory threshold and its role in assessment of aging. Percept Psychophys 54 (1993) 296-302
37. Touhara K. Deorphanizing vertebrate olfactory receptors: recent advances in odorant-response assays. Neurochem Int 51 (2007) 132-139
38. van Gemert L.J. Odour Thresholds. Compilations of odour threshold values in air, water and other media (2003), Oliemans, Punter & Partners BV, Utrecht
39. Vidic J., Grosclaude J., Monnerie R., Persuy M.A., Badonnel K., Baly C., et al. On a chip demonstration of a functional role for Odorant Binding Protein in the preservation of olfactory receptor activity at high odorant concentration. Lab Chip 8 (2008) 678-688
40. Wachowiak M., and Cohen L.B. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 32 (2001) 723-735
41. Wysocki C.J., Dalton P., Brody M.J., and Lawley H.J. Acetone odor and irritation thresholds obtained from acetone-exposed factory workers and from control (occupationally unexposed) subjects. Am Ind Hyg Assoc J 58 (1997) 704-712
42. Yoshida M. Correlation analysis of detection threshold data for 'standard test' odors. Bull Fac Sci Eng Chuo Univ 27 (1984) 343-353