Molecular cloning and oxidative modification of human lens ALDH1A1: Implication in impaired detoxification of lipid aldehydes

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 72, Issue 9, 2009, Pages 577-584

  Xiao, Tianlin ^a   Shoeb, Mohammad ^a   Siddiqui, M Saeed ^b   Zhang, Min ^a   Ramana, Kota V ^a   Srivastava, Satish K ^a   Vasiliou, Vasilis ^c   Ansari, Naseem H ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b HAMDARD UNIVERSITY   (India)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDH1A1 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ARTICLE; CATARACT; ENZYMOLOGY; GENETICS; HUMAN; LENS; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS;

ALDEHYDE DEHYDROGENASE; CATARACT; HUMANS; LENS, CRYSTALLINE; OXIDATION-REDUCTION; OXIDATIVE STRESS; RECOMBINANT PROTEINS;

EID: 65249110368     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390802706371     Document Type: Article

References (43)

1. Ansari, N. H., Wang, L., and Srivastava, S. K. 1996. Role of lipid aldehydes in cataractogenesis: Hydroxynonenal-induced cataract. Biochem. Mol. Med. 58:25-30.
2. Benedetti, A., Comporti, M., and Esterbauer, H. 1980. Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids. Biochem. Biophys. Acta 620:281-296.
3. Bonaldo, M. F., Lennon, G., and Soares, M. B. 1996. Normalization and subtraction: Two approaches to facilitate gene discovery. Genome Res. 6:791-806.
4. Bostian, K. A., and Betts, G. F. 1978. Kinetics and reaction mechanism of potassium-activated aldehyde dehydrogenase from Saccharomyces cerevisiae. Biochem. J. 173: 787-798.
5. Chandra, A., Srivastava, S., Petrash, J. M., Bhatnagar, A., and Srivastava, S. K. 1997. Modification of aldose reductase by S-nitrosogluthione. Biochemistry 36:15801-15809.
6. Chiou, S. H., Chang, C. J., Hsu, W. M., Kao, C. L., Liu, J. H., Chem, W. L., Tsai, D. C., Wu, C. C., and Chou, C. K. 2001. Elevated nitric oxide level in aqueous humor of patients with acute angle-closure glaucoma. Ophthalmologica 215:113-116.
7. Choudhary, S., Srivastava, S., Xiao, T., Andley, U. P., Srivastava, S. K., and Ansari, N. H. 2003. Metabolism of lipid derived aldehyde, 4-hydroxynonenal in human lens epithelial cells and rat lens. Invest. Ophthalmol. Vis. Sci. 44:2675-2682.
8. Choudhary, S., Xiao, T., Vergara, L. A., Srivastava, S., Nees, D., Piatigorsky, J., and Ansari, N. H. 2005. Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress. Invest. Ophthalmol. Vis. Sci. 46:259-267.
9. Crabbe, M. J. C., and Hoe, S. T. 1991. Aldehyde dehydrogenase, aldose reductase, and free radical scavengers in cataract. Enzyme 45:188-193.
10. Demaster, E. G., Redfern, B., and Nagaswa, H. T. 1998. Mechanisms of inhibition of aldehyde dehydrogenase by nitroxy, the active metabolite of the alcohol deterrent agent cyanamide. Biochem. Pharmacol. 55:2007-2015.
11. Esterbauer, H., Schaur, R. J, and Zollner, H. 1991. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol Med. 11:81-128.
12. He, N. G., Singhal, S. S., Chaubey, M., Awasthi, S., Zimniak, P., Partridge, C. A., and Awasthi, Y. C. 1996. Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells. Biochim. Biophys. Acta 1291: 182-188.
13. Hsu, L. C., Tani, K., Fujiyoshi, T., Kurachi, K., and Yoshida, A. 1985. Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2. Proc. Natl. Acad. Sci. USA 82:3771-3775.
14. Inomata, M., Hayashi, M., Shumiya, S., Kawashima, S., and Ito, Y. 2000. Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya cataract rats (SCR). J. Biochem. (Tokyo) 128:771-776.
15. Inomata, M., Hayashi, M., Shumiya, S., Kawashima, S., and Ito, Y. 2001. Involvement of inducible nitric oxide synthase in cataract formation in Shumiya cataract rat (SCR). Curr. Eye Res. 23:307-311.
16. Kao, C. L., Chou, C. K., Tsai, D. C., Hsu, W. M., Liu, J. H., Wang, C. S., Lin, J. C., Wu, C. C., Peng, C. H., Chang, C. J., Kao, C. L., and Chiou, S. H. 2002. Nitric oxide levels in the aqueous humor in cataract patients. J. Cataract Refract. Surg. 28:507-512.
17. Kikonyogo, A., Abriola, D. P., Dryjanski, M., and Pietruszko, R. 1999. Mechanism of inhibition of aldehyde dehydrogenase by citral, a retinoid antagonist. Eur. J. Biochem. 262:704-712.
18. King, G., and Holmes, R. 1998. Human ocular aldehyde dehydrogenase isozymes: Distribution and properties as major soluble proteins in cornea and lens. J. Exp. Zool. 282:12-17.
19. Kitson, T. M., and Grow, K. E. 1982. Activation of aldehyde dehydrogenase by diethylstilbestrol. In Enzymology of carbonyl metabolism: Aldehydrogenase and aldo/keto reductase, pp. 37-52. New York: Alan R. Liss.
20. Kitson, T. M., Kitson, K. E., and Moor, S. A. 2001. Interaction of sheep liver cytosolic aldehyde dehydrogenase with quercertin, resveratrol and diethylstilbestrol. Chem. Biol. Interact. 130-132:57-69.
21. Lam, J. P., Mays, D. C., and Lipsky, J. J. 1997. Inhibition of recombinant human mitochondrial and cytosolic aldehyde dehydrogenases by two candidates for the active metabolites of disulfiram. Biochemistry 36:13748-13754.
22. Lassen, N., Bateman, J. B., Estey, T., Kuszak, J. R., Nees, D. W., Piatigorsky, J., Duester, G., Day, B. J., Huang, J., Hines, L. M., and Vasiliou, V. 2007. Multiple and additive functions of ALDH3A1 and ALDH1A1: Cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice. J. Biol. Chem. 282:25668-25676.
23. Lassen, N., Black, W. J., Estey, T., and Vasiliou, V. 2008. The role of corneal crystallins in the cellular defense mechanisms against oxidative stress. Semin. Cell Dev. Biol. 19:100-112.
24. Lindahl, R., and Evces, S. 1984. Rat liver aldehyde dehydrogenase. I. Isolation and characterization of four high Km normal liver isozymes. J. Biol. Chem. 259:11986-11990.
25. Lindahl, R., and Peterson, D. R. 1991. Lipid aldehyde oxidation as a physiological role for class 3 aldehyde dehydrogenases. Biochem Pharmacol. 41:1583-1587.
26. Manzer, R., Qamar, L., Estey, T., Pappa, A., Petersen, D. R., and Vasiliou, V. 2003. Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA. DNA Cell Biol. 22: 329-238.
27. Moore, S. A., Baker, H. M., Blythe, T. J., Kitson, K. E., Kitson, T. M., and Baker, E. N. 1998. Sheep liver cytosolic aldehyde dehydrogenase: The structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases. Structure 6:1541-1551.
28. Pappa, A., Estey, T., Manzer, R., Brown, D., and Vasiliou, V. 2003. Human aldehyde dehydrogenase 3A1 (ALDH3A1). Biochemical characterization and immunohistochemical localization in the cornea. Biochem. J. 376:615-623.
29. Penzes, P., Wang, X. S., Sperkova, Z., and Napoli, J. L. 1997. Cloning of a rat cDNA encoding retinal dehydrogenase isozyme type I and its expression in E. coli. Gene 191:167-172.
30. Rafnsson, V., Olafsdottir, E., Hrfnkelsson, J., Sasaki, H., Arnarssp, A., and Jonasson, F. 2005. Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. Arch. Ophthalmol. 23:1102-1105.
31. Ramana, K. V., Chandra, D., Srivastava, S., Bhatnagar, A., and Srivastava, S. K. 2003. Nitric oxide regulates the polyol pathway of glucose metabolism in vascular smooth muscle cells. FASEB J. 17:417-425.
32. Resnikoff, S., Pascolini, D., Etya'ale, D., Kocur, I., Pararajasegaram, R., Pokharel, G. P., and Mariotti, S. P. 2004. Global data on visual impairment in the year 2002. Bull. WHO 82:844-851.
33. Schaur, R. J. 2003. Basic aspects of the biochemical reactivity of 4-hydroxynonenal. Mol. Aspects Med. 24:149-159.
34. Siems, W., and Grune, T. 2003. Intracellular metabolism of 4-hydroxynonenal. Mol. Aspects Med. 24:167-175.
35. Spector, A. 1995. Oxidative stress-induced cataract: Mechanism of action. FASEB J. 9:1173-1182.
36. Srivastava, S. K., Ansari, N. H., and Bhatnagar, A. 1990. Sugar induced cataractogenesis: a paradigm of oxidative tissue pathology? Lens Eye Toxicol. Res. 7:161-171.
37. Srivastava, S., Dixit, B. L., Cai, J., Sharma, S., Hurst, H. E., Bhatnagar, A., and Srivastava, S. K. 2000. Metabolism of lipid peroxidation product, 4-hydroxynonenal (HNE) in rat erythrocytes: Role of aldose reductase. Free Radical Biol. Med. 29:642-651.
38. Steinberg, E. P., Javitt, J. C., Sharkey, P. D., Zuckerman, A., Legro, M. W., Anderson, G. F., Bass, E. B., and O'Day, D. 1993. The content and cost of cataract surgery. Arch. Ophthalmol. 111:1041-1049.
39. Svanas, G. W., and Weiner, H. 1985. Enzymatic requirement for cyanamide inactivation of rat liver aldehyde dehydrogenase. Biochem. Pharmacol. 34:1197-1204.
40. Townsend, A. J., Leone-Kabler, S., Haynes, R. L., Wu, Y. H., Szweda, L., and Bunting, K. D. 2001. Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells. Chem. Biol. Interact. 130-132: 261-273.
41. Vasiliou, V., Bairoch, A., Tipton, K. F., and Nebert, D. W. 1999. Eukaryotic aldehyde dehydrogena (ALDH) genes: Human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping. Pharmacogenetics 9:421-434.
42. Xiao, T. L., Choudhary, S., Vergara, L. A., Van Kuijk, F. J. G. M., and Ansari, N. H. 2004. Oxidative stress induced formation of protein-4-HNE adduct in lens epithelial cells: Implication in oxidative cataractoganasis. J. Tissue Res. 4:181-188.
43. Zheng, C. F., Wang, T. T., and Weiner, H. 1993. Cloning and expression of the full-length cDNA encoding human liver class 1 and class 2 aldehyde dehydrogenase. Alcohol Clin. Exp. Res. 17:828-831.