Role of the Heparan Sulfate Proteoglycan Syndecan-1 (CD138) in Delayed-Type Hypersensitivity

Journal of Immunology

Volumn 182, Issue 8, 2009, Pages 4985-4993

  Masouleh, Behzad Kharabi ^a   Ten Dam, Gerdy B ^b   Wild, Martin K ^c   Seelige, Ruth ^c   Van Der Vlag, Johan ^b   Rops, Angelique L ^b   Echtermeyer, Frank G ^d   Vestweber, Dietmar ^c   Van Kuppevelt, Toin H ^b   Kiesel, Ludwig ^a   Götte, Martin ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD18 ANTIBODY; EPITOPE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; RANTES; SYNDECAN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; HEPARAN SULFATE; SDC1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL MOTION; CYTOLOGY; GENETICS; IMMUNOLOGY; LEUKOCYTE; METABOLISM; MOUSE MUTANT; PATHOLOGY;

ANIMALS; CELL MOVEMENT; EPITOPES; HEPARITIN SULFATE; HYPERSENSITIVITY, DELAYED; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SYNDECAN-1; UP-REGULATION;

EID: 65249094383     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0800574     Document Type: Article

References (53)

1. Grabbe, S., and T. Schwarz. 1998. Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol. Today 19: 37-44. (Pubitemid 28078607)
2. Black, C. A. 1999. Delayed type hypersensitivity: current theories with an historic perspective. Dermatol. Online J. 5: 7.
3. Abbas, A. K. 2005. Cell-mediated (type IV) hypersensitivity. In Pathologic Basis of Disease, 7th Ed. V. Kumar, A. K. Abbas, and N. Fausto, eds. Elsevier Saunders, Philadelphia, PA, pp. 216-217.
4. Staite, N. D., J. M. Justen, L. M. Sly, A. L. Beaudet, and D. C. Bullard, D. C. 1996. Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin. Blood 88: 2973-2979.
5. Shimada, Y., M. Hasegawa, Y. Kaburagi, Y. Hamaguchi, K. Komura, E. Saito, K. Takehara, D. A. Steeber, T. F. Tedder and S. Sato. 2003. L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity. J. Immunol. 170: 4325-4334. (Pubitemid 36428202)
6. Nakae, S., Y. Komiyama, S. Narumi, K. Sudo, R. Horai, Y. Tagawa, K. Sekikawa, K. Matsushima, M. Asano, and Y. Iwakura. 2003. IL-1-induced tumor necrosis factor-α elicits inflammatory cell infiltration in the skin by inducing IFN-α-inducible protein 10 in the elicitation phase of the contact hypersensitivity response. Int. Immunol. 15: 251-260. (Pubitemid 36267117)
7. Götte, M. 2003. Syndecans in inflammation. FASEB J. 17: 575-591.
8. Götte, M., and F. Echtermeyer. 2003. Syndecan-1 as a regulator of chemokine function. Sci. World J. 3: 1327-1331.
9. Bartlett, A. H., K. Hayashida, and P. W. Park. 2007. Molecular and cellular mechanisms of syndecans in tissue injury and inflammation. Mol. Cells 24: 153-166. (Pubitemid 350177174)
10. Bernfield, M., M. Götte, P.W. Park, O. Reizes, M. L. Fitzgerald, J. Lincecum, and M. Zako. 1999. Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68: 729-777. (Pubitemid 29449208)
11. Tkachenko, E., J. M. Rhodes, and M. Simons. 2005. Syndecans: New kids on the signaling block. Circ. Res. 96: 488-500. (Pubitemid 40463457)
12. Morgan, M. R., M. J. Humphries, and M. D. Bass. 2007. Synergistic control of cell adhesion by integrins and syndecans. Nat. Rev. Mol. Cell Biol. 8: 957-969.
13. Parish, C. R. 2005. Heparan sulfate and inflammation. Nat. Immunol. 6: 861-862.
14. Yip, G. W., M. Smollich, and M. Götte. 2006. Therapeutic value of glycosaminoglycans in cancer. Mol. Cancer Ther. 5: 2139-2148.
15. Wang, L., M. Fuster, P. Sriramarao, and J. D. Esko. 2005. Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses. Nat. Immunol. 6: 902-910. (Pubitemid 43090445)
16. Edovitsky, E., I. Lerner, E. Zcharia, T. Peretz, I. Vlodavsky, and M. Elkin. 2006. Role of endothelial heparanase in delayed-type hypersensitivity. Blood 107: 3609-3616.
17. McDermott, S. P., E. A. Ranheim, V. S. Leatherberry, S. S. Khwaja, K. S. Klos, and C. M. Alexander. 2007. Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development. Oncogene 26: 1407-1416.
18. Wang, Z., M. Götte, M. Bernfield, and O. Reizes. 2005. Constitutive and accelerated shedding of murine syndecan-1 is mediated by cleavage of its core protein at a specific juxtamembrane site. Biochemistry 44: 12355-12361. (Pubitemid 41324327)
19. Slimani, H., N. Charnaux, E. Mbemba, L. Saffar, R. Vassy, C. Vita, and L. Gattegno. 2003. Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages. Biochim. Biophys. Acta 1617: 80-88. (Pubitemid 37456715)
20. Götte, M., A. M. Joussen, C. Klein, P. André, D. D. Wagner, B. Kirchhof, M. T. Hinkes, A. P. Adamis, and M. Bernfield. 2002. Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature. Invest. Ophthalmol. Vis. Sci. 43: 1135-1141. (Pubitemid 34258284)
21. Götte, M., M. Bernfield, and A. M. Joussen. 2005. Increased leukocyte-endothelial interactions in syndecan-1 deficient mice involve heparan-dependent and independent steps. Curr. Eye Res. 30: 417-422. (Pubitemid 40965522)
22. Vanhoutte, D., M. Schellings, M. Götte, V. Herias, M. K. Wild, D. Vestweber, M.-A. Stepp, P. Carmeliet, Y. M. Pinto, and S. Heymans. 2007. Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction. Circulation 115: 475-482. (Pubitemid 46184199)
23. Li, Q., P. W. Park, C. L. Wilson, and W. C. Parks. 2002. Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury. Cell 111: 635-646. (Pubitemid 35441246)
24. Xu, J., P. W. Park, F. Kheradmand, and D. B. Corry. 2005. Endogenous attenuation of allergic lung inflammation by syndecan-1. J. Immunol. 174: 5758-5765. (Pubitemid 40593219)
25. Rops, A. L., M. Götte, M. H. Baselmans, M. J. van den Hoven, J. F. Lensen, T. J. Wijnhoven, L. P. van den Heuvel, T. H. van Kuppevelt, J. H. Berden, and J. van der Vlag. 2007. Syndecan-1 deficiency aggravates anti-GBM nephritis. Kidney Int. 72: 1204-1215.
26. Stepp, M. A., H. E. Gibson, P. H. Gala, D. D. Iglesia, A. Pajoohesh-Ganji, S. Pal-Gosh, M. Brown, C. Aquino, A. M. Schwartz, O. Goldberger, et al. 2002. Defects in keratinocyte activation during wound healing in syndecan-1 deficient mouse. J. Cell Sci. 115: 4517-4531.
27. Marquardt, T., T. Brune, K. Lühn, P. Zimmer, C. Körner, L. Fabritz, N. van derWerft, J. Vormoor, H. H. Freeze, F. Louwen, et al. 1999. Leukocyte adhesion deficiency II syndrome, a generalized defect in fucose metabolism. J. Pediatr. 134: 681-688.
28. van Kuppevelt, T. H., M. A. Dennissen, W. J. van Venrooij, R. M. Hoet, and J. H. Veerkamp. 1998. Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology: further evidence for heparan sulfate heterogeneity in the kidney. J. Biol. Chem. 273: 12960-12966.
29. Smits, N. C., A. A. Robbesom, E. M. Versteeg, E. M. van de Westerlo, P. N. Dekhuijzen, and T. H. van Kuppevelt. 2004. Heterogeneity of heparan sulfates in human lung. Am. J. Respir. Cell Mol. Biol. 30: 166-173.
30. Varga, G., S. Balkow, M. K. Wild, A. Stadtbaeumer, M. Krummen, T. Rothoeft, T. Higuchi, S. Beissert, K. Wethmar, K. Scharffetter-Kochanek, D. Vestweber, and S. Grabbe. 2007. Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation. Blood 109: 661-669. (Pubitemid 46105967)
31. Driessens, M. H. E., P. van Hulten, A. Zuurbier, G. La Rivière, and E. Roos. 1996. Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18: evidence that the LFA-1 binding sites for ICAM-1, -2, and -3 are distinct. J. Leukocyte Biol. 60: 758-765.
32. Bradley, P. P., D. A. Priebat, R. D. Christensen, and G. Rothstein. 1982. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78: 206-209.
33. Ten Dam, G. B., S. Kurup, E. M. van de Westerlo, E. M. Versteeg, U. Lindahl, D. Spillmann, and T. H. van Kuppevelt. 2006. 3-O-sulfated oligosaccharide structures are recognized by anti-heparan sulfate antibody HS4C3. J. Biol. Chem. 281: 4654-4662.
34. Charnaux, N., S. Brule, T. Chaigneau, L. Saffar, A. Sutton, M. Hamon, C. Prost, N. Lievre, C. Vita, and L. Gattegno. 2005. RANTES (CCL5) induces a CCR5-dependent accelerated shedding of syndecan-1 (CD138) and syndecan-4 from HeLa cells and forms complexes with the shed ectodomains of these proteoglycans as well as with those of CD44. Glycobiology 15: 119-130. (Pubitemid 40227917)
35. Götte, M. 2007. Syndecans as modulators of chemokine function. In Progress in Chemokine Research. 1st Ed. W. P. Linkes, ed. Nova Science Publishers, Hauppauge, NY, pp. 85-102.
36. Gautam, S., J. Battisto, J. A. Major, D. Armstrong, M. Stoler, and T. A. Hamilton. 1994. Chemokine expression in trinitrochlorobenzene-mediated contact hypersensitivity. J. Leukocyte Biol. 55: 452-460. (Pubitemid 24122521)
37. Tedla, N., H.-W. Wang, H. P. McNeil, N. Di Girolamo, T. Hampartzoumian, D. Wakefield, and A. Lloyd. 1998. Regulation of T lymphocyte trafficking into lymph nodes during an immune response by the chemokines macrophage inflammatory protein (MIP)-1α and MIP-1β. J. Immunol. 161: 5663-5672. (Pubitemid 28519134)
38. McHale, J. F., O. A. Harari, D. Marshall, and D. O. Haskard. 1999. Vascular endothelial cell expression of ICAM-1 and VCAM-1 at the onset of eliciting contact hypersensitivity in mice: evidence for a dominant role of TNF-α. J. Immunol. 162: 1648-1655.
39. Bode, L., C. Salvestrini, P. W. Park, J.-P. Li, J. D. Esko, Y. Yamaguchi, S. Murch, and H. H. Freeze. 2008. Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function. J. Clin. Invest. 118: 229-238.
40. Peters, K., M. Schwarz, C. Conradt, T. Nordt, M. Moser, W. Kübler, and C. Bode. 1999. Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18). Circulation 100: 1533-1539.
41. Scheynius, A., R. L. Camp, and E. Puré. 1993. Reduced contact sensitivity reactions in mice treated with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1. J. Immunol. 150: 655-663. (Pubitemid 23133643)
42. Handel, T. M., Z. Johnson, S. E. Crown, E. K. Lau, M. Sweeney, and A. E. Proudfoot. 2005. Regulation of protein function by glycosaminoglycans - as exemplified by chemokines. Annu. Rev. Biochem. 74: 385-410. (Pubitemid 40995512)
43. Marshall, L. J., L. S. P. Ramdin, T. Brooks, P. Charlton, and J. K. Shute. 2003. Plasminogen activator inhibitor-1 supports IL-8-mediated neutrophil transendothelial migration by inhibition of the constitutive shedding of endothelial IL-8/heparan sulfate/syndecan-1 complexes. J. Immunol. 171: 2057-2065.
44. Piguet, P. F., G. E. Grau, C. Hauser, and P. Vassalli. 1991. Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions. J. Exp. Med. 173: 673-679.
45. Pasparakis, M., L. Alexopoulou, V. Episkopou, and G. Kollias. 1996. Immune and inflammatory responses in TNF α-deficient mice: a critical requirement for TNF α in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184: 1397-1411. (Pubitemid 26354696)
46. Bäumer, W., U. Seegers, M. Braun, T. Tschernig, and M. Kietzmann. 2004. TARC and RANTES, but not CTACK, are induced in two models of allergic contact dermatitis: effects of cilomilast and diflorasone diacetate on T-cell-attracting chemokines. Br. J. Dermatol. 151: 823-830. (Pubitemid 39482116)
47. Proudfoot, A. E., T. M. Handel, Z. Johnson, E. K. Lau, P. LiWang, I. Clark-Lewis, F. Borlat, T. N. Wells, and M. H. Kosco-Vilbois. 2003. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc. Natl. Acad. Sci. USA 100: 1885-1890.
48. Wan, M. X., Y. Wang, Q. Liu, R. Schramm, and H. Thorlacius. 2003. CC chemokines induce P-selectin-dependent neutrophil rolling and recruitment in vivo: intermediary role of mast cells. Br. J. Pharmacol. 138: 698-706.
49. Yanaba, K., N. Mukaida, K. Matsushima, P. M. Murphy, K. Takehara, and S. Sato. 2004. Role of C-C chemokine receptors 1 and 5 and CCL3/macrophage inflammatory protein-1α in the cutaneous Arthus reaction: possible attenuation of their inhibitory effects by compensatory chemokine production. Eur. J. Immunol. 34: 3553-3561. (Pubitemid 40012173)
50. Miyazaki, D., T. Nakamura, M. Toda, K. W. Cheung-Chau, R. M. Richardson, and S. J. Ono. 2005. Macrophage inflammatory protein-1α as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactions. J. Clin. Invest. 115: 434-442. (Pubitemid 40385485)
51. Yang, Y., V. Macleod, H. Q. Miao, A. Theus, F. Zhan, J. D. Shaughnessy, Jr., J. Sawyer, J. P. Li, E. Zcharia, I. Vlodavsky, and R. D. Sanderson. 2007. Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis. J. Biol. Chem. 282: 13326-13333. (Pubitemid 47100527)
52. Wijnhoven, T. J., M. J. van den Hoven, H. Ding, T. H. van Kuppevelt, J. van der Vlag, J. H. Berden, R. A. Prinz, E. J. Lewis, M. Schwartz, and X. Xu. 2008. Heparanase induces a differential loss of heparan sulphate domains in overt diabetic nephropathy. Diabetologia 51: 372-382.
53. Ledin, J., W. Staatz, J. P. Li, M. Götte, S. Selleck, L. Kjellén, and D. Spillmann. 2004. Heparan sulfate structure in mice with genetically modified heparan sulfate production. J. Biol. Chem. 279: 42732-42741. (Pubitemid 39372160)