Role of C-C chemokine receptors 1 and 5 and CCL3/macrophage inflammatory protein-1α in the cutaneous Arthus reaction: Possible attenuation of their inhibitory effects by compensatory chemokine production

European Journal of Immunology

Volumn 34, Issue 12, 2004, Pages 3553-3561

  Yanaba, Koichi ^a,b   Mukaida, Naofumi ^a   Matsushima, Kouji ^c   Murphy, Philip M ^d   Takehara, Kazuhiko ^a   Sato, Shinichi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Arthus reaction; CCL3; CCR1; CCR5; Inflammation

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR5; LIGAND; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; RANTES;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHUS PHENOMENON; ARTICLE; ATTENUATION; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; DERMIS; MAST CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKIN EDEMA; SKIN INFLAMMATION; STATISTICAL SIGNIFICANCE; WILD TYPE;

ANIMALS; ARTHUS REACTION; CHEMOKINES; EDEMA; HEMORRHAGE; LEUKOCYTES; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; PERITONEUM; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; TIME FACTORS;

EID: 10944250647     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425426     Document Type: Article

References (58)

1. Ward, S. G., Bacon, K. and Westwick, J., Chemokines and T lymphocytes: more than an attraction. Immunity 1998. 9: 1-11.
2. Luster, A. D., Chemokines - chemotactic cytokines that mediate inflammation. N. Eng. J. Med. 1998. 338: 436-445.
3. Baggiolini, M., Dewald, B. and Moser, B., Human chemokines: an update. Annu. Rev. Immunol. 1997. 15: 675-705.
4. Strieter, R. M., Standiford, T. J., Huggnagle, G. B., Colletti, L. M., Lukas, N. W. and Kunkel, S. L., "The good, the bad, and the ugly" - the role of chemokines in models of human disease. J. Immunol. 1996. 156: 3583-3586.
5. Rollins, B. J., Chemokines. Blood 1997. 90: 909-928.
6. Proudfoot, A. E., Wells, T. N. and Clapham, P. R., Chemokine receptors - future therapeutic targets for HIV? Biochem. Pharmacol. 1999. 57: 451-463.
7. Jarmin, D. I., Rits, M., Bota, D., Gerard, N. P., Graham, G. J., Clark-Lewis, I. and Gerard, C., Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine. J. Immunol. 2000. 164: 3460-3464.
8. Su, S. B., Mukaida, N., Wang, J., Nomura, H. and Matsushima, K., Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression on various types of leukocytes. J. Leukoc. Biol. 1996. 60: 658-666.
9. Neote, K., DiGregorio, D., Mak, J. Y., Horuk, R. and Schall, T. J., Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 1993. 72: 415-425.
10. Khan, I. A., Murphy, P. M., Casciotti, L., Schwartzman, J. D., Collins, J., Gao, J. L. and Yeaman, G. R., Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection. J. Immunol. 2001. 166: 1930-1937.
11. Standiford, T. J., Kunkel, S. L., Lukacs, N. W., Greenberger, M. J., Danforth, J. M., Kunkel, R. G. and Strieter, R. M., Macrophage inflammatory protein-1 alpha mediates lung leukocyte recruitment, lung capillary leak, and early mortality in murine endotoxemia. J. Immunol. 1995. 155: 1515-1524.
12. Gao, J. L., Wynn, T. A., Chang, Y., Lee, E. J., Broxmeyer, H. E., Cooper, S., Tiffany, H. L., Westphal, H., Kwon-Chung, J. and Murphy, P. M., Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J. Exp. Med. 1997. 185: 1959-1968.
13. Domachowske, J. B., Bonville, C. A., Gao, J. L., Murphy, P. M., Easton, A. J. and Rosenberg, H. F., The chemokine macrophage-inflammatory protein-1 alpha and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection. J. Immunol. 2000. 165: 2677-2682.
14. Juremalm, M., Olsson, N. and Nilsson, G., Selective CCL5/RANTES-induced mast cell migration through interactions with chemokine receptors CCR1 and CCR4. Biochem. Biophys. Res. Commun. 2002. 297: 480-485.
15. Bonecchi, R., Bianchi, G., Bordignon, P. P., D'Ambrosio, D., Lang, R., Borsatti, A., Sozzani, S., Allavena, P., Gray, P. A., Mantovani, A. and Sinigaglia, F., Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 1998. 187: 129-134.
16. Mantovani, A., The chemokine system: redundancy for robust outputs. Immunol. Today 1999. 20: 245-257.
17. Edinger, A. L., Mankowski, J. L., Doranz, B. J., Margulies, B. J., Lee, B., Rucker, J., Sharron, M., Hoffman, T. L., Berson, J. F., Zink, M. C. et al., CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. Proc. Natl. Acad. Sci. USA 1997. 94: 14742-14747.
18. Berger, O., Gan, X., Gujuluva, C., Burns, A. R., Sulur, G., Stins, M., Way, D., Witte, M., Weinand, M., Said, J. et al., CXC and CC chemokine receptors on coronary and brain endothelia. Mol. Med. 1999. 5: 795-805.
19. Raport, C. J., Gosling, J., Schweickart, V. L., Gray, P. W. and Charo, I. F., Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha. J. Biol. Chem. 1996. 271: 17161-17166.
20. Zlotnik, A. and Yoshie, O., Chemokines: a new classification system and their role in immunity. Immunity 2000. 12: 121-127.
21. Huffnagle, G. B., McNeil, L. K., McDonald, R. A., Murphy, J. W., Toews, G. B., Maeda, N. and Kuziel, W. A., Cutting edge: role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. J. Immunol. 1999. 163: 4642-4646.
22. Belnoue, E., Kayibanda, M., Deschemin, J. C., Viguier, M., Mack, M., Kuziel, W. A. and Renia, L., CCR5 deficiency decreases susceptibility to experimental cerebral malaria. Blood 2003. 101: 4253-4259.
23. Glass, W. G., Liu, M. T., Kuziel, W. A. and Lane, T. E., Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus. Virology 2001. 288: 8-17.
24. Zhou, Y., Kurihara, T., Ryseck, R. P., Yang, Y., Ryan, C., Loy, J., Warr, G. and Bravo, R., Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J. Immunol. 1998. 160: 4018-4025.
25. + dendritic cells. Nat. Immunol. 2000. 1: 83-87.
26. Dawson, T. C., Beck, M. A., Kuziel, W. A., Henderson, F. and Maeda, N., Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus. Am. J. Pathol. 2000. 156: 1951-1959.
27. Kohl, J. and Gessner, J. E., On the role of complement and Fcγ-receptors in the Arthus reaction. Mol. Immunol. 1999. 36: 893-903.
28. Arthus, M., Injections répetées de serum de cheval chez le lapin. V. R. Soc. Biol. 1903. 55: 817-820.
29. Baumann, U., Kohl, J., Tschernig, T., Schwerter-Strumpf, K., Verbeek, J. S., Schmidt, R. E. and Gessner, J. E., A codominant role of FcγRI/III and C5aR in the reverse Arthus reaction. J. Immunol. 2000. 164: 1065-1070.
30. Hopken, U. E., Lu, B., Gerard, N. P. and Gerard, C., Impaired inflammatory responses in the reverse Arthus reaction through genetic deletion of the C5a receptor. J. Exp. Med 1997. 186: 749-756.
31. Sylvestre, D. L. and Ravetch, J. V., Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade. Science 1994. 265: 1095-1098.
32. Baumann, U., Chouchakova, N., Gewecke, B., Kohl, J., Carroll, M. C., Schmidt, R. E and Gessner, J. E., Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung. J. Immunol. 2001. 167: 1022-1027.
33. Yanaba, K., Kaburagi, Y., Takehara, K., Steeber, D. A., Tedder, T. F. and Sato, S., Relative contributions of selectins and intercellular adhesion molecule-1 to tissue injury induced by immune complex deposition. Am. J. Pathol. 2003. 162: 1463-1473.
34. Kaburagi, Y., Hasegawa, M., Nagaoka, T., Shimada, Y., Hamaguchi, Y., Komura, K., Saito, E., Yanaba, K., Takehara, K., Kadono, T. et al., The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression. J. Immunol. 2002. 168: 2970-2978.
35. Zhang, Y., Ramos, B. F. and Jakschik, B. A., Augmentation of reverse Arthus reaction by mast cells in mice. J. Clin. Invest. 1991. 88: 841-846.
36. Gommerman, J. L., Oh, D. Y., Zhou, X., Tedder, T. F., Maurer, M., Galli, S. J. and Carroll, M. C., A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation. J. Immunol. 2000. 165: 6915-6921.
37. Rosenkranz, A. R., Coxon, A., Maurer, M., Gurish, M. F., Austen, K. F., Friend, D. S., Galli, S. J. and Mayadas, T. N., Impaired mast cell development and innate immunity in Mac-1 (CD11b/CD18, CR3)-deficient mice. J. Immunol. 1998. 161: 6463-6467.
38. Ayehunie, S., Garcia-Zepeda, E. A., Hoxie, J. A., Horuk, R., Kupper, T. S., Luster, A. D. and Ruprecht, R. M., Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors. Blood 1997. 90: 1379-1386.
39. Schall, T. J., Bacon, K., Toy, K. J. and Goeddel, D. V., Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 1990. 347: 669-671.
40. Das, A. M., Ajuebor, M. N., Flower, R. J., Parretti, M. and McColl, S. R., Contrasting roles for RANTES and macrophage inflammatory protein-1 alpha (MIP-1 alpha) in a murine model of allergic peritonitis. Clin. Exp. Immunol. 1999. 117: 223-229.
41. Meurer, R., Van Riper, G., Feeney, W., Cunningham, P., Hora, D., Jr., Springer, M. S., MacIntyre, D. E., and Rosen, H., Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1 alpha, or human interleukin 8. J. Exp. Med. 1993. 178: 1913-1921.
42. Conti, P., Reale, M., Barbacane, R. C., Letourneau, R. and Theoharides, T. C., Intramuscular injection of hrRANTES causes mast cell recruitment and increased transcription of histidine decarboxylase in mice: lack of effects in genetically mast cell-deficient W/WV mice. FASEB J. 1998. 12: 1693-1700.
43. Conti, P., Reale, M., Barbacane, R. C., Felaco, M., Grillil, A. and Theoharides, T. C., Mast cell recruitment after subcutaneous injection of RANTIES in the sole of the rat paw. Br. J. Haematol. 1998. 103: 798-803.
44. Rot, A., Krieger, M., Brunner, S., Schall, T. J. and Dahinden, C. A., RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J. Exp. Med. 1992. 176: 1489-1495.
45. Davatelis, G., Wolpe, S. D., Sherry, B., Dayer, J. M., Chicheportiche, R. and Cerami, A., Macrophage inflammatory protein-1: a prostaglandin-independent endogenous pyrogen. Science 1989. 243: 1066-1068.
46. Schall, T. J., Bacon, K., Camp, R. D., Kaspari, J. W. and Goeddel, D. V., Human macrophage inflammatory protein alpha (MIP-1 alpha) and MIP-1 beta chemokines attract distinct populations of lymphocytes. J. Exp. Med. 1993. 177: 1821-1826.
47. Alam, R., Forsythe, P. A., Stafford, S., Lett-Brown, M. A. and Grant, J. A., Macrophage inflammatory protein-1 alpha activates basophils and mast cells. J. Exp. Med. 1992. 176: 781-786.
48. Wang, J. M., Sherry, B., Fivash, M. J., Kelvin, D. J. and Oppenheim, J. J., Human recombinant macrophage inflammatory protein-1 alpha and -beta and monocyte chemotactic and activating factor utilize common and unique receptors on human monocytes. J. Immunol. 1993. 150: 3022-3029.
49. Wan, M. X., Wang, Y., Liu, Q., Schramm, R. and Thorlacius, H., CC chemokines induce P-selectin-dependent neutrophil rolling and recruitment in vivo: intermediary role of mast cells. Br. J. Pharmacol. 2003. 138: 698-706.
50. Shanley, T. P., Schmal, H., Friedl, H. P., Jones, M. L. and Ward, P.A., Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats. J. Immunol. 1995. 154: 4793-4802.
51. + bone marrow progenitor cells. J. Immunol. 1991. 146: 1410-1415.
52. Silverman, A. J., Sutherland, A. K., Wilhelm, M. and Silver, R., Mast cells migrate from blood to brain. J. Neurosc. 2000. 20: 401-408.
53. Shimada, Y., Hasegawa, M., Kaburagi, Y., Hamaguchi, Y., Komura, K., Saito, E., Takehara, K., Steeber, D. A., Tedder, T. F. and Sato, S., L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity. J. Immunol. 2003. 170: 4325-4334.
54. Cook, D. N., Beck, M. A., Coffman, T. M., Kirby, S. L., Sheridan, J. F., Pragnell, I. B. and Smithies, O., Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science 1995. 269: 1583-1585.
55. Murai, M., Yoneyama, H., Ezaki, T., Suematsu, M., Terashima, Y., Harada, A., Hamada, H., Asakura, H., Ishikawa, H. and Matsushima, K., Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction. Nat. Immunol. 2003. 4: 154-160.
56. Abraham, C. and Miller, J., Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1. J. Immunol. 2001. 167: 5193-5201.
57. Fink, L., Seeger, W., Ermert, L., Hanze, J., Stahl, U., Grimminger, F., Kummer, W. and Bohle, R. M., Real-time quantitative RT-PCR after laser-assisted cell picking. Nat. Med. 1998. 4: 1329-1333.
58. Sato, S., Miller, A. S., Inaoki, M., Bock, C. B., Jansen, P. J., Tang, M. L. K. and Tedder, T. F., CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 1996. 5: 551-562.