RANTES (CCL5) induces a CCR5-dependent accelerated shedding of syndecan-1 (CD138) and syndecan-4 from HeLa cells and forms complexes with the shed ectodomains of these proteoglycans as well as with those of CD44

Glycobiology

Volumn 15, Issue 2, 2005, Pages 119-130

  Charnaux, Nathalie ^a,c   Brule, Séverine ^a,c   Chaigneau, Thomas ^a,c   Saffar, Line ^a,c   Sutton, Angela ^a,c   Hamon, Morgan ^a,c   Prost, Catherine ^a,c   Lievre, Nicole ^a,c   Vita, Claudio ^b   Gattegno, Liliane ^a,c  

^a UNIVERSITÉ PARIS 13   (France)

^b DIF   (France)

^c HÔPITAL JEAN VERDIER   (France)

Author keywords

Chemokine; Proteoglycan; RANTES; Syndecan 1; Syndecan 4

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BISINDOLYLMALEIMIDE; CHEMOKINE RECEPTOR CCR5; G PROTEIN COUPLED RECEPTOR; GAG PROTEIN; GLYCOSAMINOGLYCAN; HERMES ANTIGEN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEOGLYCAN; RANTES; SYNDECAN 1; SYNDECAN 4;

ANTIGEN EXPRESSION; ARTICLE; BIOTINYLATION; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MACROPHAGE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEOGLYCAN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION;

ANTIGENS, CD44; GENE EXPRESSION; HELA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOGLYCANS; RANTES; RECEPTORS, CCR5; SYNDECAN-1; SYNDECAN-4; SYNDECANS; TRANSFECTION;

EID: 20844452036     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/cwh148     Document Type: Article

References (52)

1. Bacon, K.B., Szabo, M.C., Yssel, H., Bolen, J.B., and Schall, T.J. (1996) RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells. J. Exp. Med., 184, 873-882.
2. Bacon, K.B., Schall, T.J., and Dairaghi, D.J. (1998) RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA. J. Immunol., 160, 1894-1900.
3. Bernfield, M., Kokenyesi, R., Kato, M., Hinkes, M.T., Spring, J., Gallo, R.L., and Lose, E.J. (1992) Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. Annu. Rev. Cell. Biol. 8, 365-393.
4. Bernfield, M., Gotte, M., Park, P.W., Reizes, O., Fitzgerald, M.L., Lincecum, J., and Zako, M. (1999) Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem., 68, 729-777.
5. Blanpain, C., Doranz, B.J., Vakili, J., Rucker, J., Govaerts, C., Baik, S.S.W., Lorthioir, O., Migeotte, I., Libert, F., Baleux, F., and others. (1999) Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein. J. Biol. Chem., 274, 34719-34727.
6. Blanpain, C., Dorantz, B.J., Bondue, A., Govaerts, C., De Leener, A., Vassart, G., Doms, R.W., Proudfoot, A., and Parmentier, M. (2003) The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle. J. Biol. Chem. 278, 5179-5187.
7. Brennan, F.R., O'Neill, J.K., Allen, S.J., Butter, C., Nuki, G., and Baker, D. (1999) CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease. Immunology, 98, 427-435.
8. Carey, D.J. (1997) Syndecans: multifunctional cell-surface co-receptors. Biochem. J., 327, 1-16.
9. Chang, T.L., Gordon, C.J., Roscic-Mrkic, B., Power, C., Proudfoot, A.E., Moore, J.P., and Trkola, A. (2002) Interaction of the CC-chemokine RANTES with glycosaminoglycans activates a p44/p42 mitogen-activated protein kinase-dependent signaling pathway and enhances human immunodeficiency virus type 1 infectivity. J. Virol., 76 2245-2254.
10. Charneau, P., Alizon, M., and Clavel, F. (1992) A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication. J. Virol., 66, 2814-2820.
11. Cichy, J. and Pure, E. (2004) Cytokines regulate the affinity of soluble CD44 for hyaluronan. FEBS Lett., 556, 69-74.
12. Clasper, S., Vekemans, S., Fiore, M., Plebanski, M., Wordsworth, P., David, G., and Jackson, D.G. (1999) Inducible expression of the cell surface heparan sulfate proteoglycan syndecan-2 (fibroglycan) on human activated macrophages can regulate fibroblast growth factor action. J. Biol. Chem., 274, 24113-24123.
13. Couchman, J.R., Chen, L., and Woods, A. (2001) Syndecans and cell adhesion. Int. Rev. Cytol., 207, 113-150.
14. David, G., Bai, X.M., Van der Schueren, B., Cassiman, J.J., and Van den Berghe, H. (1992) Developmental changes in heparan sulfate expression: in situ detection with mAbs. J. Cell. Biol., 119, 961-75.
15. Day, R.M., Mitchell, T.J., Knight, S.C., and Forbes, A. (2003) Regulation of epithelial syndecan-1 expression by inflammatory cytokines. Cytokine, 21, 224-233.
16. Favata, M.F., Horiuchi, K.Y., Manos, E.J., Daulerio, A.J., Stradley, D.A., Feeser, W.S., Van Dyk, D.E., Pitts, W.J., Earl, R.A., Hobbs, F., and others. (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem., 273, 18623-18632.
17. Fitzgerald, M.L., Wang, Z., Park, P.W., Murphy, G., and Bernfield, M. (2000) Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. J. Cell. Biol., 148, 811-824.
18. Gallo, R., Kim, C., Kokenyesi, R., Adzick, N.S., and Bernfield, M. (1996) Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin. J. Invest. Dermatol., 107, 676-683.
19. Hamon, M., Mbemba, E,, Charnaux, N., Slimani, H., Brule, S., Saffar, L., Vassy, R., Prost, C., Lievre, N., Starzec, A., and Gattegno, L. (2004) A syndecan-4/CXCR4 complex expressed on human primary lymphocytes and macrophages and HeLa cell line binds the CXC chemokine stromal cell-derived factor-1 (SDF-1). Glycobiology, 14, 311-323.
20. Hoogewerf, A.J., Kuschert, G.S., Proudfoot, A.E., Borlat, F., Clark-Lewis, I., Power, C.A., and Wells, T.N. (1997) Glycosaminoglycans mediate cell surface oligomerization of chemokines. Biochemistry, 36, 13570-13578.
21. Jalkanen, M., Rapraeger, A., Saunders, S., and Bernfield, M. (1987) Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain. J. Cell. Biol., 105, 3087-3096.
22. Kainulainen, V., Wang, H., Schick, C., and Bernfield, M. (1998) Syndecans, heparan sulfate proteoglycans, maintain the proteolytic balance of acute wound fluids. J. Biol. Chem., 273, 11563-11569.
23. Kato, M., Wang, H., Bernfield, M., Gallagher, J.T., and Turnbull, J.E. (1994) Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains. J. Biol. Chem., 269, 18881-18890.
24. Kim, C.W., Goldberger, O.A., Gallo, R.L., and Bernfield, M. (1994) Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns. Mol. Biol. Cell., 5, 797-805.
25. Kuschert, G.S., Coulin, F., Power, C.A., Proudfoot, A.E., Hubbart, R.E., Hoogewerf, A.J., and Wells, T.N. (1999) Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses. Biochemistry, 38, 12959-12968.
26. Luster, A.D. (1998) Chemokines - chemotactic cytokines that mediate inflammation. N. Engl. J. Med., 338, 436-445.
27. Luttrell, L.M., Daaka, Y., and Lefkowitz, R.J. (1999) Regulation of tyrosine kinase cascades by G-protein coupled receptor. Curr. Opin. Cell. Biol. 11, 177-183.
28. Mbemba, E., Benjouad, A., Saffar, L., and Gattegno, L. (1999) Glycans and proteoglycans are involved in the interactions of human immunodeficiency virus type 1 envelope glycoprotein and of SDF-1alpha with membrane ligands of CD4(+) CXCR4(+) cells. Virology, 265 354-364.
29. Mbemba, E., Gluckman, J.C., and Gattegno, L. (2000) Glycan and glycosaminoglycan binding properties of stromal cell-derived factor (SDF)-1alpha. Glycobiology, 10, 21-29.
30. Mbemba, E., Saffar, L., and Gattegno, L. (2002) Role of N-glycans and SDF-1alpha on the coassociation of CD4 with CXCR4 at the plasma membrane of monocytic cells and blood lymphocytes. FEBS Lett. 514, 209-213.
31. Modrowski, D., Basle, M., Lomri, A., and Marie, P.J. (2000) Syndecan-2 is involved in the mitogenic activity and signaling of granulocyte-macrophage colony-stimulating factor in osteoblasts. J. Biol. Chem., 275, 9178-9185.
32. Naot, D., Sionov, R.V., and Ish-Shalom, D. (1997) CD44: structure, function, and association with the malignant process. Adv. Cancer Res., 71, 241-319.
33. Netelenbos, T., Van den Born, J., Kessler, F.L., Zweegman, S., Merle, P.A., Van Oostveen, J.W., Zwaginga, J.J., and Dräger, A.M., (2003) Proteoglycans on bone marrow endothelial cells bind and present SDF-1 towards hematopoietic progenitor cells. Leukemia, 17, 175-184.
34. Oh, E.S., Woods, A., and Couchman, J.R. (1997) Multimerization of the cytoplasmic domain of syndecan-4 is required for its ability to activate protein kinase C. J. Biol. Chem., 272 11805-11811.
35. Pollok-Kopp, B., Schwarze, K., Baradari, V.K., and Oppermann, M. (2003) Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies. J. Biol. Chem., 278, 2190-2198.
36. Ponta, H., Sherman, L., and Herrlich, P.A. (2003) CD44: from adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell. Biol., 4, 33-45.
37. Reiland, J., Ott, V.L., Lebakken, C.S., Yeaman, C., and McCarthy, J. (1996) Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1. Biochem. J. 319, 39-47.
38. Roscic-Mrkic, B., Fischer, M., Leemann, C., Manrique, A., Gordon, C.J., Moore, J.P., Proudfoot, A.E., and Trkola, A. (2003) RANTES (CCL5) uses the proteoglycan CD44 as an auxiliary receptor to mediate cellular activation signals and HIV-1 enhancement. Blood, 102 1169-1177.
39. Samson, M., LaRosa, G., Libert, F., Paindavoine, P., Detheux, M., Vassart, G., and Parmentier, M. (1997) The second extracellular loop of CCR5 is the major determinant of ligand specificity. J. Biol. Chem. 272, 24934-24941.
40. Sanderson, R.D., Turnbull, J.E., Gallagher, J.T., and Lander, A.D. (1994) Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior. J. Biol. Chem., 269, 13100-13106.
41. Saunders, S., Jalkanen, M., O'Farrell, S., and Bernfield, M. (1989) Molecular cloning of syndecan, an integral membrane proteoglycan. J. Cell. Biol., 108, 1547-1556.
42. Schwabe, R.F., Bataller, R., and Brenner, D.A. (2003) Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration. Am. J. Physiol. Gastrointest. Liver Physiol. 285 G949-G958.
43. Slimani, H., Charnaux, N., Mbemba, E., Saffar, L., Vassy, R., Vita, C., and Gattegno, L. (2003a) Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages. Biochem. Biophys. Acta, 1617, 80-88.
44. Slimani, H., Charnaux, N., Mbemba, E., Saffar, L., Vassy, R., Vita, C., and Gattegno, L. (2003b) Binding of the CC-chemokine RANTES to syndecan-1 and syndecan-4 expressed on HeLa cells. Glycobiology, 13, 623-634.
45. Simons, M. and Horowitz, A. (2001) Syndecan-4-mediated signalling. Cell Signal., 13, 855-862.
46. Subramanian, S.V., Fitzgerald, M.L., and Bernfield, M. (1997) Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation. J. Biol. Chem., 272, 14713-14720.
47. Tilton, B,, Ho, L., Oberlin, E., Loetscher, P., Baleux, F., Clark-Lewis, I., and Thelen, M. (2000) Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. J. Exp. Med., 192, 313-324.
48. Toullec, D.P., Pianetti, H., Coste, P., Bellevergue, T., Grand-Perret, M., Ajakane, M., Baudet, V., Boissin, P., Boursier, E., Loriollet, F., Duhamel, L., Charon, D., and Kirilovsky, J. (1991) The bisindolyl-maleimide GF109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem., 266, 15771-15781.
49. Woods, A., and Couchman, J.R. (1998) Syndecans: synergistic activators of cell adhesion. Trends Cell. Biol., 8, 189-192.
50. Ylisastigui, L., Vizzavona, J., Drakopoulou, E., Paindavoine, P., Calvo, C. F., Parmentier, M., Gluckman, J.C., and Vita, C. (1998) Synthetic full-length and truncated RANTES inhibit HIV-1 infection of primary macrophages. AIDS, 12, 977-984.
51. Zimmermann, P. and David, G. (1999) The syndecans, tuners of transmembrane signaling. FASEB J., 13(suppl), S91-S100.
52. Zlotnik, A., and Yoshie, O. (2000) Chemokines: a new classification system and their role in immunity. Immunity, 12 121-127.