-
1
-
-
0037419677
-
Determination of plasma topotecan and its metabolite N-desmethyl topotecan as both lactone and total form by reversed-phase liquid chromatography with fluorescence detection
-
Bai F, Kirstein MN, Hanna SK, Iacono LC, Johnston B and Stewart CF. Determination of plasma topotecan and its metabolite N-desmethyl topotecan as both lactone and total form by reversed-phase liquid chromatography with fluorescence detection. Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences 2003; 784: 225-232.
-
(2003)
Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences
, vol.784
, pp. 225-232
-
-
Bai, F.1
Kirstein, M.N.2
Hanna, S.K.3
Iacono, L.C.4
Johnston, B.5
Stewart, C.F.6
-
2
-
-
0029656180
-
Cerebrospinal fluid pharmacokinetics and penetration of continuous infusion topotecan in children with central nervous system tumors
-
Baker SD, Heideman RL, Crom WR, Kuttesch JF, Gajjar A and Stewart CF. Cerebrospinal fluid pharmacokinetics and penetration of continuous infusion topotecan in children with central nervous system tumors. Cancer Chemotherapy and Pharmacology 1996; 37: 195-202.
-
(1996)
Cancer Chemotherapy and Pharmacology
, vol.37
, pp. 195-202
-
-
Baker, S.D.1
Heideman, R.L.2
Crom, W.R.3
Kuttesch, J.F.4
Gajjar, A.5
Stewart, C.F.6
-
3
-
-
30344447967
-
Instability of calcium channel antagonists during sample preparation for LC-MS-MS analysis of serum samples
-
Baranda AB, Alonso RM, Jiménez RM and Weinmann W. Instability of calcium channel antagonists during sample preparation for LC-MS-MS analysis of serum samples. Forensic Science International 2006; 156: 23-34.
-
(2006)
Forensic Science International
, vol.156
, pp. 23-34
-
-
Baranda, A.B.1
Alonso, R.M.2
Jiménez, R.M.3
Weinmann, W.4
-
4
-
-
17444414653
-
Liquid chromatographic-tandem mass spectrometric assay for the simultaneous quantification of Camptosar and its metabolite SN-38 in mouse plasma and tissues
-
Bardin S, Guo W, Johnson JL, Khan S, Ahmad A, Duggan JX, Ayoub J and Ahmad I. Liquid chromatographic-tandem mass spectrometric assay for the simultaneous quantification of Camptosar and its metabolite SN-38 in mouse plasma and tissues. Journal of Chromatography A 2005; 1073: 249-255.
-
(2005)
Journal of Chromatography A
, vol.1073
, pp. 249-255
-
-
Bardin, S.1
Guo, W.2
Johnson, J.L.3
Khan, S.4
Ahmad, A.5
Duggan, J.X.6
Ayoub, J.7
Ahmad, I.8
-
5
-
-
0025597927
-
High performance liquid chromatographic analysis of the new antitumour drug SK&F 104864-A (NSC 609699) in plasma
-
Beijnen JH, Smith BR, Keijer WJ, van Gijn R, ten Bokkel Huinink WW, Vlasveld LT, Rodenhius S and Uderberg WJ. High performance liquid chromatographic analysis of the new antitumour drug SK&F 104864-A (NSC 609699) in plasma. Journal of Pharmaceutical and Biomedical Analysis 1990; 8: 789-794.
-
(1990)
Journal of Pharmaceutical and Biomedical Analysis
, vol.8
, pp. 789-794
-
-
Beijnen, J.H.1
Smith, B.R.2
Keijer, W.J.3
van Gijn, R.4
ten Bokkel Huinink, W.W.5
Vlasveld, L.T.6
Rodenhius, S.7
Uderberg, W.J.8
-
6
-
-
0031887882
-
Plasma and cerebrospinal fluid pharmacokinetics of 9-aminocamptothecin (9-AC), irinotecan (CPT-11), and SN-38 in nonhuman primates
-
Blaney SM, Takimoto C, Murry DJ, Kuttesch N, McCully C, Cole DE, Godwin K and Balis FM. Plasma and cerebrospinal fluid pharmacokinetics of 9-aminocamptothecin (9-AC), irinotecan (CPT-11), and SN-38 in nonhuman primates. Cancer Chemotherapy Pharmacology 1998; 41: 464-468.
-
(1998)
Cancer Chemotherapy Pharmacology
, vol.41
, pp. 464-468
-
-
Blaney, S.M.1
Takimoto, C.2
Murry, D.J.3
Kuttesch, N.4
McCully, C.5
Cole, D.E.6
Godwin, K.7
Balis, F.M.8
-
7
-
-
12444336983
-
High-performance liquid chromatographic assay for the determination of total and free topotecan in the presence and absence of anti-topotecan antibodies in mouse plasma
-
Chen J and Balthasar JP. High-performance liquid chromatographic assay for the determination of total and free topotecan in the presence and absence of anti-topotecan antibodies in mouse plasma. Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences 2005; 816: 183-192.
-
(2005)
Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences
, vol.816
, pp. 183-192
-
-
Chen, J.1
Balthasar, J.P.2
-
8
-
-
34447275732
-
Effect of injection routes on pharmacokinetics and lactone/carboxylate equilibrium of 9-nitrocamptothecin in rats
-
Chen J, Ping Q, Guo J, Liu M and Cai B. Effect of injection routes on pharmacokinetics and lactone/carboxylate equilibrium of 9-nitrocamptothecin in rats. International Journal of Pharmaceutics 2007; 340: 29-33.
-
(2007)
International Journal of Pharmaceutics
, vol.340
, pp. 29-33
-
-
Chen, J.1
Ping, Q.2
Guo, J.3
Liu, M.4
Cai, B.5
-
9
-
-
36749063882
-
Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography
-
de Vries NA, Ouwehand M, Buckle T, Beijnen JH and van Tellingen O. Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography. Biomedical Chromatography 2007; 21: 1191-1200.
-
(2007)
Biomedical Chromatography
, vol.21
, pp. 1191-1200
-
-
de Vries, N.A.1
Ouwehand, M.2
Buckle, T.3
Beijnen, J.H.4
van Tellingen, O.5
-
10
-
-
0033032877
-
Comparative brain tissue distribution of camptothecin and topotecan in the rat
-
El-Gizawy SA and Hedaya MA. Comparative brain tissue distribution of camptothecin and topotecan in the rat. Cancer Chemotherapy and Pharmacology 1999; 43: 364-370.
-
(1999)
Cancer Chemotherapy and Pharmacology
, vol.43
, pp. 364-370
-
-
El-Gizawy, S.A.1
Hedaya, M.A.2
-
12
-
-
16244370770
-
Novel camptothecin derivatives
-
Legarza K and Yang LX. Novel camptothecin derivatives. In Vivo 2005; 19: 283-292.
-
(2005)
In Vivo
, vol.19
, pp. 283-292
-
-
Legarza, K.1
Yang, L.X.2
-
13
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu LF. DNA topoisomerase poisons as antitumor drugs. Annual Review of Biochemistry 1989; 58: 351-375.
-
(1989)
Annual Review of Biochemistry
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
14
-
-
0029888994
-
Sensitive high-performance liquid chromatographic fluorescence assay for the quantitation of topotecan (SKF 104864-A) and its lactone ring-opened (hydroxyl acid) in human plasma and urine
-
Loos WJ, Stoter G, Verweij J and Schellens JH. Sensitive high-performance liquid chromatographic fluorescence assay for the quantitation of topotecan (SKF 104864-A) and its lactone ring-opened (hydroxyl acid) in human plasma and urine. Journal of Chromatography B: Biomedical Applications 1996; 678: 309-315.
-
(1996)
Journal of Chromatography B: Biomedical Applications
, vol.678
, pp. 309-315
-
-
Loos, W.J.1
Stoter, G.2
Verweij, J.3
Schellens, J.H.4
-
15
-
-
0033926690
-
Determination of camptothecin analogs in biological matrices by high-performance liquid chromatography
-
Loos WJ, de Bruijn P, Verweij J and Sparreboom A. Determination of camptothecin analogs in biological matrices by high-performance liquid chromatography. Anticancer Drugs 2000; 11: 315-324
-
(2000)
Anticancer Drugs
, vol.11
, pp. 315-324
-
-
Loos, W.J.1
de Bruijn, P.2
Verweij, J.3
Sparreboom, A.4
-
16
-
-
0038167666
-
The camptothecins
-
Pizzolato JF and Saltz LB. The camptothecins. Lancet 2003; 361: 2235-2242.
-
(2003)
Lancet
, vol.361
, pp. 2235-2242
-
-
Pizzolato, J.F.1
Saltz, L.B.2
-
17
-
-
0029034767
-
High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma
-
Rosing H, Doyle E, Davies BE and Beijnen JH. High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma. Journal of Chromatography B: Biomedical Applications 1995; 668: 107-115.
-
(1995)
Journal of Chromatography B: Biomedical Applications
, vol.668
, pp. 107-115
-
-
Rosing, H.1
Doyle, E.2
Davies, B.E.3
Beijnen, J.H.4
-
18
-
-
0032898870
-
Quantitation of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods
-
Rosing H, van Zomeren DM, Doyle E, ten Bokkel Huinink WW, Schellens LH, Bult A and Beijnen JH. Quantitation of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods. Journal of Chromatography B: Biomedical Science Applications 1999; 727: 191-203.
-
(1999)
Journal of Chromatography B: Biomedical Science Applications
, vol.727
, pp. 191-203
-
-
Rosing, H.1
van Zomeren, D.M.2
Doyle, E.3
ten Bokkel Huinink, W.W.4
Schellens, L.H.5
Bult, A.6
Beijnen, J.H.7
-
19
-
-
39749201504
-
An integrated method for metabolite detection and identification using a linear ion trap/Orbitrap mass spectrometer and multiple data processing techniques: Application to indinavir metabolite detection
-
Ruan Q, Peterman S, Szewc MA, Ma L, Cui D, Humpreys GW and Zhu M. An integrated method for metabolite detection and identification using a linear ion trap/Orbitrap mass spectrometer and multiple data processing techniques: application to indinavir metabolite detection. Journal of Mass Spectrometry 2008; 43: 251-261.
-
(2008)
Journal of Mass Spectrometry
, vol.43
, pp. 251-261
-
-
Ruan, Q.1
Peterman, S.2
Szewc, M.A.3
Ma, L.4
Cui, D.5
Humpreys, G.W.6
Zhu, M.7
-
20
-
-
0033024749
-
The accumulation of topotecan in 9L glioma and in brain parenchyma with and without dexamethasone administration
-
Straathof CS, van den Bent MJ, Loos WJ, Vecht CJ and Schellens JH. The accumulation of topotecan in 9L glioma and in brain parenchyma with and without dexamethasone administration. Journal of Neurooncology 1999; 42: 117-122.
-
(1999)
Journal of Neurooncology
, vol.42
, pp. 117-122
-
-
Straathof, C.S.1
van den Bent, M.J.2
Loos, W.J.3
Vecht, C.J.4
Schellens, J.H.5
-
21
-
-
0027940704
-
A pharmacokinetic model of topotecan clearance from plasma and cerebrospinal fluid
-
Sung C, Blaney SM, Cole DE, Balis FM and Dedrick RL. A pharmacokinetic model of topotecan clearance from plasma and cerebrospinal fluid. Cancer Research 1994; 54: 118-122.
-
(1994)
Cancer Research
, vol.54
, pp. 118-122
-
-
Sung, C.1
Blaney, S.M.2
Cole, D.E.3
Balis, F.M.4
Dedrick, R.L.5
-
22
-
-
0030900145
-
Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer
-
ten Bokkel Huinink WW, Gore M, Carmichael J, Gordon A, Malfetano J, Hudosn I, Broom C, Scarabelli C, Davidson N, Spanczynski M, Bolis G, Malmstrom H, Coleman R, Fields SC and Heron JF. Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer. Journal of Clinical Oncology 1997; 15: 2183-2193.
-
(1997)
Journal of Clinical Oncology
, vol.15
, pp. 2183-2193
-
-
ten Bokkel Huinink, W.W.1
Gore, M.2
Carmichael, J.3
Gordon, A.4
Malfetano, J.5
Hudosn, I.6
Broom, C.7
Scarabelli, C.8
Davidson, N.9
Spanczynski, M.10
Bolis, G.11
Malmstrom, H.12
Coleman, R.13
Fields, S.C.14
Heron, J.F.15
-
23
-
-
33745128074
-
Liquid chromatography/tandem triple-quadrupole mass spectrometry for determination of paclitaxel in rat tissues
-
Tong X, Zhou J and Tan Y. Liquid chromatography/tandem triple-quadrupole mass spectrometry for determination of paclitaxel in rat tissues. Rapid Communications in Mass Spectrometry 2006; 20: 1905-1912.
-
(2006)
Rapid Communications in Mass Spectrometry
, vol.20
, pp. 1905-1912
-
-
Tong, X.1
Zhou, J.2
Tan, Y.3
-
24
-
-
14744284722
-
Simple and sensitive high performance liquid, chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of topotecan in human plasma
-
Vali AM, Shafaghi B and Dadashzadeh S. Simple and sensitive high performance liquid, chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of topotecan in human plasma. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2005; 818: 205-212.
-
(2005)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.818
, pp. 205-212
-
-
Vali, A.M.1
Shafaghi, B.2
Dadashzadeh, S.3
-
25
-
-
0033044111
-
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer
-
von Pawel J, Schiller JH, Shepherd FA, Fields SZ, Kleisbauer JP, Chrysson NG, Stewart DJ, Clark PI, Palmer MC, Depierre A, Carmichael J, Krebs JB, Ross G, Lane SR and Gralla R. Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer. Journal of Clinical Oncology 1999; 17: 68-667.
-
(1999)
Journal of Clinical Oncology
, vol.17
, pp. 68-667
-
-
von Pawel, J.1
Schiller, J.H.2
Shepherd, F.A.3
Fields, S.Z.4
Kleisbauer, J.P.5
Chrysson, N.G.6
Stewart, D.J.7
Clark, P.I.8
Palmer, M.C.9
Depierre, A.10
Carmichael, J.11
Krebs, J.B.12
Ross, G.13
Lane, S.R.14
Gralla, R.15
-
26
-
-
0036521770
-
Induction of cardiac cytochrome p450 in cocaine-treated mice
-
Wang JF, Yang Y, Sullivan MF, Min J, Cai J, Zeldin DC, Xiao YF and Morgan JP. Induction of cardiac cytochrome p450 in cocaine-treated mice. Experimental Biology Medicine (Maywood) 2002; 227: 182-188.
-
(2002)
Experimental Biology Medicine (Maywood)
, vol.227
, pp. 182-188
-
-
Wang, J.F.1
Yang, Y.2
Sullivan, M.F.3
Min, J.4
Cai, J.5
Zeldin, D.C.6
Xiao, Y.F.7
Morgan, J.P.8
-
27
-
-
41149180635
-
High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry
-
Wen B, Ma L, Nelson SD and Zhu M. High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry. Analytical Chemistry 2008; 80: 1788-1799.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 1788-1799
-
-
Wen, B.1
Ma, L.2
Nelson, S.D.3
Zhu, M.4
-
28
-
-
46849091191
-
Mass defect profiles of biological matrices and the general applicability of mass defect filtering for metabolite detection
-
Zhang H, Zhu M, Ray KL, Ma L and Zhang D. Mass defect profiles of biological matrices and the general applicability of mass defect filtering for metabolite detection. Rapid Communications in Mass Spectrometry 2008; 22: 2082-2088.
-
(2008)
Rapid Communications in Mass Spectrometry
, vol.22
, pp. 2082-2088
-
-
Zhang, H.1
Zhu, M.2
Ray, K.L.3
Ma, L.4
Zhang, D.5
-
29
-
-
35848937158
-
Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high resolution mass spectrometry and mass defect filtering
-
Zhu M, Ma L, Zhang H and Humphreys GW. Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high resolution mass spectrometry and mass defect filtering. Analytical Chemistry 2007; 79: 8333-8341.
-
(2007)
Analytical Chemistry
, vol.79
, pp. 8333-8341
-
-
Zhu, M.1
Ma, L.2
Zhang, H.3
Humphreys, G.W.4
-
30
-
-
85161745387
-
-
Zunino F and Pratesi G. Camptothecins in clinical development. Expert Opinion in Investigational Drugs 2004; 13: 269-284.
-
Zunino F and Pratesi G. Camptothecins in clinical development. Expert Opinion in Investigational Drugs 2004; 13: 269-284.
-
-
-
|