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Volumn 1073, Issue 1-2, 2005, Pages 249-255

Liquid chromatographic-tandem mass spectrometric assay for the simultaneous quantification of Camptosar® and its metabolite SN-38 in mouse plasma and tissues

(8) Bardin, Sofia a Guo, Wei a Johnson, Jenifer L a Khan, Sumsullah a Ahmad, Ateeq a Duggan, Jeffrey X a Ayoub, Jennifer a Ahmad, Imran a

a NeoPharm Inc (United States)

Author keywords

Camptothecin; CPT 11; Liquid chromatography; Mice; Pharmacokinetics; SN 38; Tandem mass spectrometry

Indexed keywords

ACETONITRILE; ASSAYS; MASS SPECTROMETRY; METABOLITES; PHARMACOKINETICS; PROTEINS; REACTION KINETICS; TISSUE;

AMMONIUM ACETATE; CAMPTOSAR (CPT-11); CAMPTOTHECIN (CPT); LINEAR REGRESSION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ACETONITRILE; AMMONIUM ACETATE; DRUG METABOLITE; IRINOTECAN;

ACCURACY; ANIMAL TISSUE; CALCULATION; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; DRUG DISTRIBUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; LINEAR REGRESSION ANALYSIS; LIQUID CHROMATOGRAPHY; MONITORING; MOUSE; NONHUMAN; PH MEASUREMENT; PLASMA; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION; TISSUE HOMOGENATE;

EID: 17444414653 PISSN: 00219673 EISSN: None Source Type: Journal
DOI: 10.1016/j.chroma.2004.08.060 Document Type: Conference Paper

Times cited : (37)

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