-
1
-
-
0028677806
-
Preclinical and clinical development of camptothecins
-
1. Costin D, Potmesil M. Preclinical and clinical development of camptothecins. Adv Pharmacol 1994; 29B: 51-72.
-
(1994)
Adv Pharmacol
, vol.29 B
, pp. 51-72
-
-
Costin, D.1
Potmesil, M.2
-
2
-
-
0027972726
-
Novel topoisomerase I inhibitors, topotecan and irinotecan
-
2. Creemers GJ, Lund B, Verweij J. Novel topoisomerase I inhibitors, topotecan and irinotecan. Cancer Treat Rev 1994; 20: 73-96.
-
(1994)
Cancer Treat Rev
, vol.20
, pp. 73-96
-
-
Creemers, G.J.1
Lund, B.2
Verweij, J.3
-
3
-
-
0030752757
-
Topoisomerase-I inhibitors: The relevance of prolonged exposure for present clinical development
-
3. Gerrits CJH, Jonge MJA de, Schellens JHM, Stoter G, Verweij J. Topoisomerase-I inhibitors: the relevance of prolonged exposure for present clinical development. Br J Cancer 1997; 76: 952-62.
-
(1997)
Br J Cancer
, vol.76
, pp. 952-962
-
-
Gerrits, C.J.H.1
De Jonge, M.J.A.2
Schellens, J.H.M.3
Stoter, G.4
Verweij, J.5
-
5
-
-
0033377034
-
Role of erythrocytes and serum proteins in the kinetic profile of total 9-amino-20-S-camptothecin in humans
-
5. Loos WJ, Verweij J, Gelderblom AJ, et al. Role of erythrocytes and serum proteins in the kinetic profile of total 9-amino-20-S-camptothecin in humans. Anti-Cancer Drugs 1999; 10: 705-10.
-
(1999)
Anti-Cancer Drugs
, vol.10
, pp. 705-710
-
-
Loos, W.J.1
Verweij, J.2
Gelderblom, A.J.3
-
6
-
-
0028937909
-
The important role of albumin in determining the relative human blood stabilities of the camptothecin anticancer drugs
-
6. Burke TG, Munshi CB, Mi Z, Jiang Y. The important role of albumin in determining the relative human blood stabilities of the camptothecin anticancer drugs. J Pharm Sci 1995; 84: 518-9.
-
(1995)
J Pharm Sci
, vol.84
, pp. 518-519
-
-
Burke, T.G.1
Munshi, C.B.2
Mi, Z.3
Jiang, Y.4
-
7
-
-
0024358188
-
DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
-
7. Giovanella BC, Stehlin JS, Wall ME, et al. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 1989; 246: 1046-8.
-
(1989)
Science
, vol.246
, pp. 1046-1048
-
-
Giovanella, B.C.1
Stehlin, J.S.2
Wall, M.E.3
-
8
-
-
0008531763
-
Bioanalytical liquid chromatographic method validation: A review of current practices and procedures
-
Utrecht University
-
8. Rosing H, Man WY, Doyle E, Bult A, Beijnen JH. Bioanalytical liquid chromatographic method validation: a review of current practices and procedures (thesis). In: Bioanalytical chromatographic assays for new anticancer agents and their application in clinical pharmacologic research. Utrecht University 1998: 15-40.
-
(1998)
Bioanalytical Chromatographic Assays for New Anticancer Agents and Their Application in Clinical Pharmacologic Research
, pp. 15-40
-
-
Rosing, H.1
Man, W.Y.2
Doyle, E.3
Bult, A.4
Beijnen, J.H.5
-
9
-
-
0025597927
-
High-performance liquid chromatographic analysis of the new antitumor drug SKF 104864-A (NSC 609699) in plasma
-
9. Beijnen JH, Smith BR, Keijer WJ, et al. High-performance liquid chromatographic analysis of the new antitumor drug SKF 104864-A (NSC 609699) in plasma. J Pharm Biomed Anal 1990; 8: 789-94.
-
(1990)
J Pharm Biomed Anal
, vol.8
, pp. 789-794
-
-
Beijnen, J.H.1
Smith, B.R.2
Keijer, W.J.3
-
10
-
-
0029888994
-
Sensitive high-performance liquid chromatographic fluorescence assay for the quantitation of topotecan (SKF 104864-A) and its lactone ring-opened product (hydroxy-acid) in human plasma and urine
-
10. Loos WJ, Stoter G, Verweij J, Schellens JHM. Sensitive high-performance liquid chromatographic fluorescence assay for the quantitation of topotecan (SKF 104864-A) and its lactone ring-opened product (hydroxy-acid) in human plasma and urine. J Chromatogr B 1996; 678: 309-15.
-
(1996)
J Chromatogr B
, vol.678
, pp. 309-315
-
-
Loos, W.J.1
Stoter, G.2
Verweij, J.3
Schellens, J.H.M.4
-
11
-
-
0032898870
-
Quantitation of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods
-
11. Rosing H, Van Zomeren DM, Doyle E, et al. Quantitation of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods. J Chromatogr B 1999; 727: 191-203.
-
(1999)
J Chromatogr B
, vol.727
, pp. 191-203
-
-
Rosing, H.1
Van Zomeren, D.M.2
Doyle, E.3
-
12
-
-
0029034767
-
High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma
-
12. Rosing H, Doyle E, Davies BE, Beijnen JH. High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma. J Chromatogr B 1995; 668: 107-15.
-
(1995)
J Chromatogr B
, vol.668
, pp. 107-115
-
-
Rosing, H.1
Doyle, E.2
Davies, B.E.3
Beijnen, J.H.4
-
13
-
-
0030296623
-
The impact of column temperature in the high-performance liquid chromatographic analysis of topotecan in rat and dog plasma
-
13. Rosing H, Doyle E, Beijnen JH. The impact of column temperature in the high-performance liquid chromatographic analysis of topotecan in rat and dog plasma. J Pharm Biomed Anal 1996; 15: 279-86.
-
(1996)
J Pharm Biomed Anal
, vol.15
, pp. 279-286
-
-
Rosing, H.1
Doyle, E.2
Beijnen, J.H.3
-
14
-
-
0030891273
-
Simple and versatile high-performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of camptothecin anticancer drugs
-
14. Warner DL, Burke TG. Simple and versatile high-performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of camptothecin anticancer drugs. J Chromatogr B 1997; 691: 161-71.
-
(1997)
J Chromatogr B
, vol.691
, pp. 161-171
-
-
Warner, D.L.1
Burke, T.G.2
-
15
-
-
9544234452
-
Phase II and pharmacologic study of topotecan administered as a 21 days continuous infusion to patients with colorectal cancer
-
15. Creemers GJ, Gerrits CJH, Schellens JHM, et al. Phase II and pharmacologic study of topotecan administered as a 21 days continuous infusion to patients with colorectal cancer. J Clin Oncol 1996; 14: 2540-5.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2540-2545
-
-
Creemers, G.J.1
Gerrits, C.J.H.2
Schellens, J.H.M.3
-
16
-
-
0031056424
-
Phase I and pharmacologic study of oral topotecan administered twice daily for 21-days to adult patients with solid tumors
-
16. Creemers GJ, Gerrits CJH, Eckard JR, et al. Phase I and pharmacologic study of oral topotecan administered twice daily for 21-days to adult patients with solid tumors. J Clin Oncol 1997; 15: 1087-93.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1087-1093
-
-
Creemers, G.J.1
Gerrits, C.J.H.2
Eckard, J.R.3
-
17
-
-
15444361370
-
Oral topotecan given once or twice daily for ten days: A phase I and pharmacology study in adult patients with solid tumors
-
17. Gerrits CJH, Burris H, Schellens JHM, et al. Oral topotecan given once or twice daily for ten days: a phase I and pharmacology study in adult patients with solid tumors. Clin Cancer Res 1998; 4: 1153-8.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1153-1158
-
-
Gerrits, C.J.H.1
Burris, H.2
Schellens, J.H.M.3
-
18
-
-
0032101820
-
Five days of oral topotecan (Hycamtin), a phase I and pharmacologic study in adult patients with solid tumors
-
18. Gerrits CJH, Burris H, Schellens JHM, et al. Five days of oral topotecan (Hycamtin), a phase I and pharmacologic study in adult patients with solid tumors. Eur J Cancer 1998; 34: 1030-5.
-
(1998)
Eur J Cancer
, vol.34
, pp. 1030-1035
-
-
Gerrits, C.J.H.1
Burris, H.2
Schellens, J.H.M.3
-
19
-
-
17144433130
-
Phase I and pharmacologic study of oral topotecan and intravenous cisplatin: Sequence dependent hematologic side-effects
-
19. De Jonge MJA, Loos WJ, Gelderblom H, et al. Phase I and pharmacologic study of oral topotecan and intravenous cisplatin: sequence dependent hematologic side-effects. J Clin Oncol 2000; 18: 2104-15.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2104-2115
-
-
De Jonge, M.J.A.1
Loos, W.J.2
Gelderblom, H.3
-
20
-
-
0030915059
-
Comparison of filter and tunable fluorescence detection for the hplc simultaneous quantitation of lactone and carboxylate forms of topotecan in plasma
-
20. Warner DL, Burke TG. Comparison of filter and tunable fluorescence detection for the HPLC simultaneous quantitation of lactone and carboxylate forms of topotecan in plasma. J Liq Chromatogr Rel Technol 1997; 20: 1523-37.
-
(1997)
J Liq Chromatogr Rel Technol
, vol.20
, pp. 1523-1537
-
-
Warner, D.L.1
Burke, T.G.2
-
21
-
-
0026538734
-
Simultaneous determination of the camptothecin analogue CPT-11 and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in cancer patients
-
21. Barilero I, Gandia D, Armand JP, et al. Simultaneous determination of the camptothecin analogue CPT-11 and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in cancer patients. J Chromatogr B 1992; 575: 275-80.
-
(1992)
J Chromatogr B
, vol.575
, pp. 275-280
-
-
Barilero, I.1
Gandia, D.2
Armand, J.P.3
-
22
-
-
0027937924
-
Reversed-phase high-performance liquid chromatographic method for the simultaneous quantitation of the carboxylate and lactone forms of the camptothecin derivate irinotecan, CPT-11, and its metabolite SN-38 in plasma
-
22. Rivory LP, Robert J. Reversed-phase high-performance liquid chromatographic method for the simultaneous quantitation of the carboxylate and lactone forms of the camptothecin derivate irinotecan, CPT-11, and its metabolite SN-38 in plasma. J Chromatogr B 1994; 661: 133-41.
-
(1994)
J Chromatogr B
, vol.661
, pp. 133-141
-
-
Rivory, L.P.1
Robert, J.2
-
23
-
-
0031749185
-
Sensitive determinatiation of the carboxylate and lactone forms of the novel antitumour drug irinotecan and its active metabolite SN-38 in plasma by high-performance liquid chromatography
-
23. Herben VMM, Mazee D, Van Zomeren DM, et al. Sensitive determinatiation of the carboxylate and lactone forms of the novel antitumour drug irinotecan and its active metabolite SN-38 in plasma by high-performance liquid chromatography. J Liq Chromatogr Rel Technol 1998; 21: 1541-58.
-
(1998)
J Liq Chromatogr Rel Technol
, vol.21
, pp. 1541-1558
-
-
Herben, V.M.M.1
Mazee, D.2
Van Zomeren, D.M.3
-
24
-
-
0029164578
-
High-performance liquid chromatographic determination of irinotecan (CPT-11) and its active metabolite (SN-38) in human plasma
-
24. Sumiyoshi H, Fujiwara Y, Ohune T, Yamaoka N, Tamura K, Yamakido M. High-performance liquid chromatographic determination of irinotecan (CPT-11) and its active metabolite (SN-38) in human plasma. J Chromatogr B 1995; 670: 309-16.
-
(1995)
J Chromatogr B
, vol.670
, pp. 309-316
-
-
Sumiyoshi, H.1
Fujiwara, Y.2
Ohune, T.3
Yamaoka, N.4
Tamura, K.5
Yamakido, M.6
-
25
-
-
0030741008
-
Simultaneous determination of the lactone and carboxylate forms of 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in rat plasma by high performance liquid chromatography
-
25. Kaneda N, Hosokawa Y, Yokokura T. Simultaneous determination of the lactone and carboxylate forms of 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in rat plasma by high performance liquid chromatography. Biol Pharm Bull 1997; 20: 815-9.
-
(1997)
Biol Pharm Bull
, vol.20
, pp. 815-819
-
-
Kaneda, N.1
Hosokawa, Y.2
Yokokura, T.3
-
26
-
-
0030815672
-
Determination of irinotecan (CPT-11) and its active metabolite SN-38 in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection
-
26. De Bruijn P, Verweij J, Loos WJ, Nooter K, Stoter G, Sparreboom A. Determination of irinotecan (CPT-11) and its active metabolite SN-38 in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr B 1997; 698: 277-85.
-
(1997)
J Chromatogr B
, vol.698
, pp. 277-285
-
-
De Bruijn, P.1
Verweij, J.2
Loos, W.J.3
Nooter, K.4
Stoter, G.5
Sparreboom, A.6
-
27
-
-
0032493799
-
Liquid chromatographic determination of irinotecan and three major metabolites in human plasma, urine and feces
-
27. Sparreboom A, De Bruijn P, De Jonge MJA, et al. Liquid chromatographic determination of irinotecan and three major metabolites in human plasma, urine and feces. J Chromatogr B 1998; 712: 225-35.
-
(1998)
J Chromatogr B
, vol.712
, pp. 225-235
-
-
Sparreboom, A.1
De Bruijn, P.2
De Jonge, M.J.A.3
-
28
-
-
0031785256
-
Irinotecan (CPT-11) metabolism and disposition in cancer patients
-
28. Sparreboom A, De Jonge MJA, De Bruijn P, et al. Irinotecan (CPT-11) metabolism and disposition in cancer patients. Clin Cancer Res 1998; 4: 2747-54.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2747-2754
-
-
Sparreboom, A.1
De Jonge, M.J.A.2
De Bruijn, P.3
-
29
-
-
0031865841
-
Trace analysis of SN-38 in human plasma by high-performance liquid chromatography
-
29. Rivory LP, Findlay M, Clarke S, Bishop J. Trace analysis of SN-38 in human plasma by high-performance liquid chromatography. J Chromatogr B 1998; 714: 355-9.
-
(1998)
J Chromatogr B
, vol.714
, pp. 355-359
-
-
Rivory, L.P.1
Findlay, M.2
Clarke, S.3
Bishop, J.4
-
30
-
-
0033541694
-
Femtomole quantitation of 7-ethyl-10-hydroxycamptothecine (SN-38) in plasma samples by reversed-phase high-performance liquid chromatography
-
30. De Bruijn P, De Jonge MJA, Verweij J, et al. Femtomole quantitation of 7-ethyl-10-hydroxycamptothecine (SN-38) in plasma samples by reversed-phase high-performance liquid chromatography. Anal Biochem 1999; 269: 174-8.
-
(1999)
Anal Biochem
, vol.269
, pp. 174-178
-
-
De Bruijn, P.1
De Jonge, M.J.A.2
Verweij, J.3
-
31
-
-
0031722623
-
Simultaneous determination of the lactone and carboxylate forms of the camptothecin derivate CPT-11 and its metabolite SN-38 in plasma by high-performance liquid chromatography
-
31. Chollet DF, Goumaz L, Renard A, et al. Simultaneous determination of the lactone and carboxylate forms of the camptothecin derivate CPT-11 and its metabolite SN-38 in plasma by high-performance liquid chromatography. J Chromatogr B 1998; 718: 163-75.
-
(1998)
J Chromatogr B
, vol.718
, pp. 163-175
-
-
Chollet, D.F.1
Goumaz, L.2
Renard, A.3
-
32
-
-
0033008532
-
High-performance liquid chromatographic method for simultaneous determination of the camptothecin derivate irinotecan hydrochloride, CPT-11, and its metabolites SN-38 and SN-38 glucuronide in rat plasma with a fully automated on-line solid-phase extraction system, PROSPEKT
-
32. Kurita A, Kaneda N. High-performance liquid chromatographic method for simultaneous determination of the camptothecin derivate irinotecan hydrochloride, CPT-11, and its metabolites SN-38 and SN-38 glucuronide in rat plasma with a fully automated on-line solid-phase extraction system, PROSPEKT. J Chromatogr B 1999; 724: 335-44.
-
(1999)
J Chromatogr B
, vol.724
, pp. 335-344
-
-
Kurita, A.1
Kaneda, N.2
-
33
-
-
0032727882
-
Sensitive determination of irinotecan (CPT-11) and its active metabolite SN-38 in human serum using liquid chromatography-electrospray mass spectrometry
-
33 Ragot S, Marquet P, Lachatre F, et al. Sensitive determination of irinotecan (CPT-11) and its active metabolite SN-38 in human serum using liquid chromatography-electrospray mass spectrometry. J Chromatogr B 1999; 736: 175-84.
-
(1999)
J Chromatogr B
, vol.736
, pp. 175-184
-
-
Ragot, S.1
Marquet, P.2
Lachatre, F.3
-
35
-
-
0027093373
-
Liquid chromatographic analysis of 9-aminocamptothecin in plasma monitored by fluorescence induced upon postcolumn acidification
-
35. Supko JG, Malspeis L. Liquid chromatographic analysis of 9-aminocamptothecin in plasma monitored by fluorescence induced upon postcolumn acidification. J Liq Chromatogr 1992; 15: 3261-83.
-
(1992)
J Liq Chromatogr
, vol.15
, pp. 3261-3283
-
-
Supko, J.G.1
Malspeis, L.2
-
36
-
-
0028256230
-
Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography
-
36. Takimoto CH, Klercker RW, Dahut WL, et al. Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography. J Chromatogr B 1994; 655: 97-104.
-
(1994)
J Chromatogr B
, vol.655
, pp. 97-104
-
-
Takimoto, C.H.1
Klercker, R.W.2
Dahut, W.L.3
-
37
-
-
0030792576
-
Determination of the lactone and lactone plus carboxylate forms of 9-aminocamptothecin in human plasma by senstive high-performance liquid chromatography with fluorescence detection
-
37. Loos WF, Sparreboom A, Verweij J, Nooter K, Stoter G, Schellens JHM. Determination of the lactone and lactone plus carboxylate forms of 9-aminocamptothecin in human plasma by senstive high-performance liquid chromatography with fluorescence detection. J Chromatogr B 1997; 694: 435-41.
-
(1997)
J Chromatogr B
, vol.694
, pp. 435-441
-
-
Loos, W.F.1
Sparreboom, A.2
Verweij, J.3
Nooter, K.4
Stoter, G.5
Schellens, J.H.M.6
-
38
-
-
0002771486
-
High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma
-
38. Van Gijn R, Herben VMM, Hillebrand MJX, Ten Bokkel Huinink WW, Bult A, Beijnen JH. High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma. J Pharm Biomed Anal 1998; 17: 1257-65.
-
(1998)
J Pharm Biomed Anal
, vol.17
, pp. 1257-1265
-
-
Van Gijn, R.1
Herben, V.M.M.2
Hillebrand, M.J.X.3
Ten Bokkel Huinink, W.W.4
Bult, A.5
Beijnen, J.H.6
-
39
-
-
0005380455
-
Enhanced in vivo amitumor efficacy of the liposome formulated topoisomerase I inhibitor lurtotecan
-
39. Emerson DL, Amirghahari N, Bendele R, et al. Enhanced in vivo amitumor efficacy of the liposome formulated topoisomerase I inhibitor Lurtotecan. Proc Am Ass Cancer Res 1999; 40: 151.
-
(1999)
Proc Am Ass Cancer Res
, vol.40
, pp. 151
-
-
Emerson, D.L.1
Amirghahari, N.2
Bendele, R.3
-
40
-
-
0028797459
-
High-performance liquid chromatographic analysis of the lactone and carboxylate forms of a topoisomerase I inhibitor (the antitumor drug GI147211 ) in plasma
-
40. Stafford CG, Claire RL St. High-performance liquid chromatographic analysis of the lactone and carboxylate forms of a topoisomerase I inhibitor (the antitumor drug GI147211 ) in plasma. J Chromatogr B 1995; 663: 119-26.
-
(1995)
J Chromatogr B
, vol.663
, pp. 119-126
-
-
Stafford, C.G.1
St. Claire, R.L.2
-
41
-
-
0029583157
-
Determination of GI147211 in human blood by HPLC with fluorescence detection
-
41. Selinger K, Smith G, Depee S, Aureche C. Determination of GI147211 in human blood by HPLC with fluorescence detection. J Pharm Biomed Anal 1995; 13: 1521-30.
-
(1995)
J Pharm Biomed Anal
, vol.13
, pp. 1521-1530
-
-
Selinger, K.1
Smith, G.2
Depee, S.3
Aureche, C.4
-
42
-
-
0033984541
-
Liposomal lurtotecan (NX211): Determination of total drug levels in human plasma and urine by reversed-phase high-performance liquid chromatography
-
42. Loos WJ, Kehrer D, Brouwer E, et al. Liposomal lurtotecan (NX211): determination of total drug levels in human plasma and urine by reversed-phase high-performance liquid chromatography. J Chromatogr B 2000; 738: 155-63.
-
(2000)
J Chromatogr B
, vol.738
, pp. 155-163
-
-
Loos, W.J.1
Kehrer, D.2
Brouwer, E.3
|