ING1a and ING1b different expressed in sporadic hepatocellular carcinoma;Differente expression de l'ING1a et l'ING1b dans le carcinome hepatocellulaire sporadique

Pathologie Biologie

Volumn 57, Issue 3, 2009, Pages

  Chen, X ^a,b   Du, J ^b   Zhu, T ^b  

^a University of Medical Sciences   (China)

^b TIANJIN UNIVERSITY   (China)

Author keywords

HCC; Immunohistochemical; ING; ING1b; Isoforms; RT PCR

Indexed keywords

MESSENGER RNA; PROTEIN ING1A; PROTEIN ING1B; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; ING1 PROTEIN, HUMAN; ISOPROTEIN; NUCLEAR PROTEIN; PRIMER DNA; SIGNAL PEPTIDE;

ADVANCED CANCER; ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER STAGING; CELL NUCLEUS; CONTROLLED STUDY; HEPATOMA CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER CELL CARCINOMA; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; BIOSYNTHESIS; DISEASE COURSE; DRUG EFFECT; EXON; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENETICS; INTRON; LIVER TUMOR; METABOLISM; PATHOLOGY;

CARCINOMA, HEPATOCELLULAR; DISEASE PROGRESSION; DNA PRIMERS; EXONS; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRONS; LIVER NEOPLASMS; NUCLEAR PROTEINS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 65249083495     PISSN: 03698114     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.patbio.2008.02.009     Document Type: Article

References (26)

1. Garkavtsev I., Kazarov A., Gudkov A., and Riabowol K. Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation. Nat Genet 14 (1996) 415-420
2. Garkavtsev I., Demetrick D., and Riabowol K. Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene (ING1). Cytogenet Cell Genet 76 (1997) 176-178
3. Feng X., Hara Y., and Riabowol K. Different HATS of the ING1 gene family. Trends Cell Biol 12 (2002) 532-538
4. Jager D., Stockert E., Scanlan M.J., Gure A.O., Jager E., Knuth A., et al. Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene. Cancer Res 59 (1999) 6197-6204
5. Vieyra D., Loewith R., Scott M., Bonnefin P., Boisvert F.M., Cheema P., et al. Human ING1 proteins differentially regulate histone acetylation. J Biol Chem 277 (2002) 29832-29839
6. Vieyra D., Toyama T., Hara Y., Boland D., Johnston R., and Riabowol K. ING1 isoforms differentially affect apoptosis in a cell age-dependent manner. Cancer Res 62 (2002) 4445-4452
7. Kataoka H., Bonnefin P., Vieyra D., Feng X., Hara Y., Miura Y., et al. ING1 represses transcription by direct DNA binding and through effects on p53. Cancer Res 63 (2003) 5785-5792
8. Tokunaga E., Maehara Y., Oki E., Kitamura K., Kakeji Y., Ohno S., et al. Diminished expression of ING1 mRNA and the correlation with p53 expression in breast cancers. Cancer Lett 152 (2000) 15-22
9. Ohmori M., Nagai M., Tasaka T., Koeffler H.P., Toyama T., Riabowol K., et al. Decreased expression of p33ING1 mRNA in lymphoid malignancies. Am J Hematol 62 (1999) 118-119
10. Oki E., Maehara Y., Tokunaga E., Kakeji Y., and Sugimachi K. Reduced expression of p33(ING1) and the relationship with p53 expression in human gastric cancer. Cancer Lett 147 (1999) 157-162
11. Chen L., Matsubara N., Yoshino T., Nagasaka T., Hoshizima N., Shirakawa Y., et al. Genetic alterations of candidate tumor suppressor ING1 in human esophageal squamous cell cancer. Cancer Res 61 (2001) 4345-4349
12. Campos E.I., Cheung Jr. K.J., Murray A., Li S., and Li G. The novel tumour suppressor gene ING1 is overexpressed in human melanoma cell lines. Br J Dermatol 146 (2002) 574-580
13. Chen B., Campos E.I., Crawford R., Martinka M., and Li G. Analyses of the tumour suppressor ING1 expression and gene mutation in human basal cell carcinoma. Int J Oncol 22 (2003) 927-931
14. Tallen G., Riabowol K., and Wolff J.E. Expression of p33ING1 mRNA and chemosensitivity in brain tumor cells. Anticancer Res 23 (2003) 1631-1635
15. Vieyra D., Senger D.L., Toyama T., Muzik H., Brasher P.M., Johnston R.N., et al. Altered subcellular localization and low frequency of mutations of ING1 in human brain tumors. Clin Cancer Res 9 (2003) 5952-5961
16. Sanchez-Carbayo M., Socci N.D., Lozano J.J., Li W., Charytonowicz E., Belbin T.J., et al. Gene discovery in bladder cancer progression using cDNA microarrays. Am J Pathol 163 (2003) 505-516
17. Edmondson H.A., and Steiner P.E. Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer 7 (1954) 462-503
18. Greene F.L. AJCC cancer staging manual. 6th Ed. (2002), Springer, New York
19. Gunduz M., Ouchida M., Fukushima K., et al. Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas. Cancer Res 60 (2000) 3143-6.2
20. Sanchez-Cespedes M., Okami K., Cairns P., and Sidransky D. Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions. Genes Chromosomes Cancer 27 (2000) 319-322
21. Saito A., Furukawa T., Fukushige S., Koyama S., Hoshi M., Hayashi Y., et al. p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1. J Hum Genet 45 (2000) 177-181
22. Toyama T., Iwase H., Watson P., et al. Suppression of ING1 expression in sporadic breast cancer. Oncogene 18 (1999) 5187-5193
23. Cheung K-JJ Jr., Bush J., Jia W., and Li G. Expression of the novel tumour suppressor p33ING1 is independent of p53. Br J Cancer 83 (2000) 1468-1472
24. Gunduz M., Ouchida M., Fukushima K., Hanafusa H., Etani T., Nishioka S., et al. Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas. Cancer Res 60 12 (2000) 3143-3146
25. Nouman G.S., Anderson J.J., Wood K.M., Lunec J., Hall A.G., Reid M.M., et al. Loss of nuclear expression of the p33(ING1b) inhibitor of growth protein in childhood acute lymphoblastic leukaemia. J Clin Pathol 55 (2002) 596-601
26. Nouman G.S., Angus B., Lunec J., Crosier S., Lodge A., and Anderson J.J. Comparative assessment expression of the inhib itor of growth 1 gene (ING1) in normal and neoplastic tissues. Hybrid Hybridomics 21 (2002) 1-10