The novel tumour suppressor gene ING1 is overexpressed in human melanoma cell lines

British Journal of Dermatology

Volumn 146, Issue 4, 2002, Pages 574-580

  Campos, E I ^a   Cheung Jr , K J J ^a   Murray, A ^a   Li, S ^a   Li, G ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b JACK BELL RESEARCH CENTRE   (Canada)

Author keywords

DNA sequencing; Melanoma; Mutation; p33ING1; Single strand conformation polymorphism analysis

Indexed keywords

MESSENGER RNA; PROTEIN; PROTEIN ING1; PROTEIN P33; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL LEVEL; CODON; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA SEQUENCE; EXON; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA CELL; NORMAL HUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; SILENT GENE; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

CELL CYCLE PROTEINS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENES, TUMOR SUPPRESSOR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MELANOCYTES; MELANOMA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SKIN NEOPLASMS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0036239695     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2002.04641.x     Document Type: Article

References (33)

1. The pathogenesis of melanoma induced by ultraviolet radiation
2. Understanding the trends in melanoma incidence and mortality: Where do we stand?
3. The DNA damage spectrum produced by simulated sunlight
4. Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells
5. Excision repair of pyrimidine dimers induced by simulated solar radiation in the skin of patients with basal cell carcinoma
6. ING1 promotes neoplasmic transformation
7. Genomic structure of the human ING1 gene and tumor suppressor-specific mutations detected in head and neck squamous cell carcinomas
8. ING1 cooperates with p53 in cell growth control
9. A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis
10. ING1 is independent of p53
11. The tumor suppressor candidate p33 (ING1) mediates repair of UV-damaged DNA
12. Suppression of ING1 expression in sporadic breast cancer
13. TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients
14. p53 mutations and expression in breast carcinoma in situ
15. Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer
16. On the spontaneous mutability of CpG sites in cultured S49 mouse lymphoma cells
17. ING1 mRNA in lymphoid malignancies
18. ING1 and the relationship with p53 expression in human gastric cancer
19. The candidate tumour suppressor gene, ING1, is retained in colorectal carcinomas
20. Mutation, allelotying, and transcription analyses of the p53 gene in prostatic carcinoma
21. Activation of p73 silent allele in lung cancer
22. Expression of mutant p53 in melanoma
23. Overexpression of p53 is a late event in the development of malignant melanoma
24. p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis
25. Frequent mutations of the p53 gene in cutaneous melanoma of the nodular type
26. p53 gene mutation and expression in naevi and melanomas
27. Mutation and expression of TP53 in malignant melanomas
28. Prognostic significance of p53 over-expression in thin melanomas
29. Prognostic implications of p53 overexpression in cutaneous melanoma from sun-exposed and nonexposed sites
30. p53 expression and risk factors for cutaneous melanoma: A case-control study
31. Wild-type p53 gene transfer inhibits invasion and reduces matrix metalloproteinase-2 levels in p53-mutated human melanoma cells
32. Chemotherapy-induced apoptosis in melanoma cells is p53-dependent
33. p53-dependent apoptosis in melanoma cells after treatment with camptothecin