Effects of dietary spirulina on vascular reactivity

Journal of Medicinal Food

Volumn 12, Issue 1, 2009, Pages 15-20

  Juarez Oropeza M A ^a   Mascher, D ^a   Torres Duran P V ^a   Farias, J M ^a   Paredes Carbajal, M C ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antihypertensive activity; Antioxidant activity; Lipids; Nitric oxide; Prostanoids; Spirulina maxima

Indexed keywords

ARACHIDONIC ACID; ASPARTATE AMINOTRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ICOSANOID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; PROBIOTIC AGENT; TRIACYLGLYCEROL;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD VESSEL TONE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; LIPID BLOOD LEVEL; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; SPIRULINA MAXIMA; VASCULAR RING; VASOMOTOR REFLEX;

ADOLESCENT; ADULT; AGED; ANIMALS; AORTA; ARACHIDONIC ACID; BLOOD PRESSURE; CHOLESTEROL; CHOLESTEROL, LDL; EICOSANOIDS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INDOMETHACIN; MALE; MIDDLE AGED; NITRIC OXIDE; OBESITY; PHENYLEPHRINE; PHYTOTHERAPY; PLANT PREPARATIONS; RATS; RATS, WISTAR; SPIRULINA; TRIGLYCERIDES; VASOMOTOR SYSTEM; YOUNG ADULT;

ARTHROSPIRA; RATTUS NORVEGICUS; SPIRULINA; SPIRULINA MAXIMA;

EID: 64949199633     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2007.0713     Document Type: Article

References (39)

1. Ramamoorthy A, Premakumari S: Effect of supplementation of Spirulina on hypercholesterolemic patients. J Food Sci Technol 1996;33:124-127.
2. Kato T, Takemoto K, Katayama H, Kuwabara Y: Effects of Spirulina (Spirulina platensis) on dietary hypercholesterolemia in rats. J Jpn Soc Nutr Food Sci 1984;37:323-332.
3. Becker EW, Jakober B, Luft D, Schmulling RM: Clinical and biochemical evaluations of the alga Spirulina with regard to its application in the treatment of obesity. A double-blind cross-over study. Nutr Rep Int 1986;33:565-574.
4. Chamorro G, Salazar M, Araujo KG, dos Santos CP, Ceballos G, Castillo LF: Update on the pharmacology of Spirulina (Arthrospira), an unconventional food. Arch Latinoam Nutr 2002;52:232-240.
5. Braunwald E: Shattuck Lecture - cardiovascular medicine at the turn of the millennium: triumphs, concerns and opportunities. N Engl J Med 1997;337:1360-1369.
6. Dobrian AD, Davies MJ, Schriver SD, Lauterio TJ, Prewitt RL: Oxidative stress in a rat model of obesity-induced hypertension. Hypertension 2001;37:554-560.
7. Roberts CK, Vaziri ND, Barnard RJ: Effect of diet and exercise intervention on blood pressure, insulin oxidative stress, and nitric oxide availability. Circulation 2002;106:2530-2532.
8. Bohlen HG, Nase GP: Obesity lowers hyperglycemic threshold for impaired in vivo endothelial nitric oxide function. Am J Phys-iol Heart Circ Physiol 2002;283:H391-H397.
9. Salt IP, Morrow VA, Brandie FM, Connell JM, Petrie JR: High glucose inhibits insulin stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phospho-rylation in human aortic endothelial cells. J Biol Chem 2003; 278:18791-18797.
10. Ross R: Atherosclerosis - an inflammatory disease. N Engl J Med 1999;340:115-126.
11. Ridker PM, Hennekens CH, Buring JE, Rifai N: C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000;342: 836-843.
12. Quoc KP, Pascaud M: Effects of dietary gamma-linolenic acid on the tissue phospholipids fatty acid composition and the synthesis of eicosanoids in rats. Ann Nutr Metab 1996;40:99-108.
13. Gonzalez R, Rodriguez S, Romay C, Ancheta O, Gonzalez A, Arnesto J, Ramirez D, Merino N: Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. Pharmacol Res 1999;39:55-59.
14. Reddy MC, Subhashini J, Mahipal SV, Bhat VB, Srinivas Reddy P, Kiranmai G, Madyastha KM, Reddanna P: C-phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophages. Biochem Biophys Res Commun 2003;304:385-392.
15. Bhat VB, Madyastha KM: C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro. Biochem Biophys Res Commun 2000;275:20-25.
16. Denzlnger C, Mess T, Sagebiel-Kohler S, Lemmen C, Jacob K, Wilmanns W, Adam O: Modulation of the endogenous leukotriene production by fish oil and vitamin E. J Lipid Mediat Cell Signal 1995;11:119-132.
17. Kaji T, Fujiwara Y, Inomata Y, Hamada C, Yamamoto C, Shi-mada S, Lee JB, Hayashi T: Repair of wounded monolayers of cultured bovine aortic endothelial cells is inhibited by calcium Spirulan, a novel sulfated polysaccharide isolated from Spirulina platensis. Life Sci 2002;70:1841-1848.
18. Yamamoto C, Shimada S, Fujiwara Y, Lee JB, Hayashi T, Kaji T: Proteoglycans released from cultured bovine aortic endothelial cell layers by sodium spirulan are both perlecan and biglycan. Biol Pharm Bull 2005;28:32-36.
19. Markov KhM: Prostacyclin-thromboxane balance and risk factors of ischemic heart disease. Kardiologiia 1989;29:5-12.
20. Naderali EK, Williams G: Prolonged endothelial-dependent and -independent arterial dysfunction induced in the rat by short-term feeding with a high-fat, high sucrose diet. Atherosclerosis 2003;166:253-259.
21. Schiffrin EL: A critical review of the role of endothelial factors in the pathogenesis of hypertension. J Cardiovasc Pharmacol 2001;38(Suppl):S3-S6.
22. Banos G, Carvajal K, Cardoso G, Zamora J, Franco M: Vascular reactivity and effect of serum in a rat model of hypertriglyc-eridemia and hypertension. Am J Hypertens 1997;10:379-388.
23. Stepp DW, Frisbee JC: Augmented adrenergic vasoconstriction in hypertensive diabetic obese Zucker rats. Am J Physiol Heart Circ Physiol 2002;282:H816-H820.
24. He Y, MacLeod KM: Modulation of noradrenaline-induced vaso-constriction in isolated perfused mesenteric arterial beds from obese Zucker rats in the presence and absence of insulin. Can J Physiol Pharmacol 2002;80:171-179.
25. Xavier FE, Davel AP, Rossoni LV, Vassallo DV: Time-dependent hyperreactivity to phenylephrine in aorta from untreated diabetic rats: role of prostanoids and calcium mobilization. Vascul Pharmacol 2003;40:67-76.
26. Kimura I, Pancho LR, Isoi Y, Kimura M: Diabetes-induced enhancement of prostanoid-stimulated contraction in mesenteric veins of mice. Jpn J Pharmacol 1989;51:403-410.
27. Traupe T, Lang M, Goettsch W, MÅnter K, Morawietz H, Vet-ter W, Barton M: Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression. J Hypertens 2002;20:2239-2245.
28. Richey JM, Si X, Halter JB, Webb RC: Fructose perfusion in rat mesenteric arteries impairs endothelium-dependent vasodilation. Life Sci 1998;62:PL55-PL62.
29. Nava P, Guarner V, Posadas R, Perez I, Baños G: Insulin induces endothelin release and vasoreactivity in hypertriglyceridemic and hypertensive rats. Am J Physiol 1999;277:H399-H404.
30. 2 by different organs of genetically hypertensive (SHR) and obese hypertensive (SHR-fa/fa) rats. Prostaglandins Leukot Med 1987;26:21-32.
31. Paredes-Carbajal MC, Torres-Durán PV, Díaz-Zagoya JC, Mascher D, Juárez-Oropeza MA: Effects of dietary Spirulina maxima on endothelium dependent vasomotor responses of rat aortic rings. Life Sci 1997;61:PL211-PL219.
32. Miller VM, Vanhoutte PM: Endothelium dependent contractions to arachidonic acid are mediated by products of cyclooxygenase. Am J Physiol 1985;248:H432-H437.
33. Torres-Durán PV, Ferreira-Hermosillo A, Juárez-Oropeza MA: Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report. Lipids Health Dis (Online) doi 10.1186/1476-511X-6-33 published November 26, 2007.
34. Parikh P, Mani U, Iver U: Role of Spirulina in the control of glycemia and lipidemia in type 2 diabetes mellitus. J Med Food 2001;4:193-199.
35. Samuels R, Mani UV, Nayak US: Hypocholesterolemic effect of Spirulina in patients with hyperlipidemic nephrotic syndrome. J Med Food 2002;5:91-96.
36. Nagaoka S, Shimizu K, Kaneko H, Shibayama F, Morikawa K, Kanamaru Y, Otsuka A, Hirashi T, Kato T: A novel protein Cphycocyanin plays a crucial role in the hypocholesterolemic action of Spirulina platensis concentrate in rats. J Nutr 2005;135: 2425-2430.
37. Li-Kun H, Dong-Xia L, Lan X, Xiao-Jie G, Yasumasa K, Isao S, Hiromichi O: Isolation of pancreatic lipase activity-inhibitory component of Spirulina platensis and it reduce postprandial triacylglycerolemia. Yakugaku Zasshi 2006;126:43-49.
38. McCarty MF: Clinical potential of Spirulina as a source of phycocyanobilin. J Med Food 2007;10:566-570.
39. 2 receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes 2002;51:198-203.