High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells

Journal of Biological Chemistry

Volumn 278, Issue 21, 2003, Pages 18791-18797

  Salt, Ian P ^a   Morrow, Valerie A ^a,b   Brandie, Fiona M ^a   Connell, John M C ^b   Petrie, John R ^b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b WESTERN INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELLS; INSULIN; NITROGEN OXIDES; PROTEINS; SYNTHESIS (CHEMICAL);

PHOSPHORYLATION;

GLUCOSE;

CALCIUM ION; CBL PROTEIN; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN CAP; PROTEIN KINASE B; PROTEIN KINASE C INHIBITOR; SERINE; UNCLASSIFIED DRUG; CBL ASSOCIATED PROTEIN, CAP; CBL PROTEIN, HUMAN; CBL-ASSOCIATED PROTEIN, CAP; CYTOSKELETON PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE 2 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-2 PROTEIN; NOS3 PROTEIN, HUMAN; ONCOPROTEIN; PHOSPHOPROTEIN; PHOSPHOSERINE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; UBIQUITIN PROTEIN LIGASE;

AORTA; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYNTHESIS; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; VASCULAR ENDOTHELIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AORTA; CELLS, CULTURED; CYTOSKELETAL PROTEINS; ENDOTHELIUM, VASCULAR; GLUCOSE; HUMANS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-CBL; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 0038482055     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210618200     Document Type: Article

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