Modulation of noradrenaline-induced vasoconstriction in isolated perfused mesenteric arterial beds from obese Zucker rats in the presence and absence of insulin

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 3, 2002, Pages 171-179

  He, Yi ^a   MacLeod, Kathleen M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Hyperinsulinemia; Hypertensive Zucker obese rat; Insulin resistance; Mesenteric arterial bed; Noradrenaline

Indexed keywords

7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN RECEPTOR ANTAGONIST; INDOMETACIN; INSULIN; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; PROSTAGLANDIN; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2 RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CONSTRICTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; HYPERINSULINEMIA; HYPERTENSION; INSULIN RESISTANCE; MALE; MESENTERIC ARTERY; MESENTERY BLOOD FLOW; NONHUMAN; OBESITY; PERFUSION PRESSURE; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE;

ANIMALS; CYCLOOXYGENASE INHIBITORS; INDOMETHACIN; INSULIN; INSULIN RESISTANCE; MALE; MESENTERIC ARTERIES; NITRIC OXIDE SYNTHASE; NOREPINEPHRINE; OBESITY; RATS; RATS, ZUCKER; RECEPTORS, ENDOTHELIN; RECEPTORS, PROSTAGLANDIN; RECEPTORS, THROMBOXANE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 0036202415     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-015     Document Type: Article

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