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Volumn 100, Issue 8, 2009, Pages 1219-1229

Prognostic markers in cancer: The evolution of evidence from single studies to meta-analysis, and beyond

Author keywords

Biomarker; Evidence synthesis; Guidelines; Primary studies; Prognosis; Prognostic tumour marker

Indexed keywords

PROTEIN P53;

EID: 64949190936     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604999     Document Type: Review
Times cited : (111)

References (80)
  • 1
    • 0035963980 scopus 로고    scopus 로고
    • Systematic reviews of evaluations of prognostic variables
    • Altman DG (2001) Systematic reviews of evaluations of prognostic variables. BMJ 323: 224-228
    • (2001) BMJ , vol.323 , pp. 224-228
    • Altman, D.G.1
  • 3
    • 0028179558 scopus 로고
    • Dangers of using 'optimal' cutpoints in the evaluation of prognostic factors
    • Altman DG, Lausen B, Sauerbrei W, Schumacher M (1994) Dangers of using 'optimal' cutpoints in the evaluation of prognostic factors. J Natl Cancer Inst 86: 829-835
    • (1994) J Natl Cancer Inst , vol.86 , pp. 829-835
    • Altman, D.G.1    Lausen, B.2    Sauerbrei, W.3    Schumacher, M.4
  • 4
    • 0032445262 scopus 로고    scopus 로고
    • Methodological challenges in the evaluation of prognostic factors in breast cancer
    • Altman DG, Lyman GH (1998) Methodological challenges in the evaluation of prognostic factors in breast cancer. Breast Cancer Res Treat 52: 289-303
    • (1998) Breast Cancer Res Treat , vol.52 , pp. 289-303
    • Altman, D.G.1    Lyman, G.H.2
  • 5
    • 0034728356 scopus 로고    scopus 로고
    • What do we mean by validating a prognostic model?
    • Altman DG, Royston P (2000) What do we mean by validating a prognostic model? Stat Med 19: 453-473
    • (2000) Stat Med , vol.19 , pp. 453-473
    • Altman, D.G.1    Royston, P.2
  • 6
    • 64949158851 scopus 로고    scopus 로고
    • Altman DG, Trivella M, Pezzella F, Harris AL, Pastorino U (2006) Systematic review of multiple studies of prognosis: the feasibility of obtaining individual patient data. I. In Advances in Statistical Methods for the Health Sciences, Auget J-L, Balakrishnan N, Mesbah M, Molenberghs G (eds), pp 3-18. Birkhäuser: Boston
    • Altman DG, Trivella M, Pezzella F, Harris AL, Pastorino U (2006) Systematic review of multiple studies of prognosis: the feasibility of obtaining individual patient data. I. In Advances in Statistical Methods for the Health Sciences, Auget J-L, Balakrishnan N, Mesbah M, Molenberghs G (eds), pp 3-18. Birkhäuser: Boston
  • 7
    • 0041560072 scopus 로고    scopus 로고
    • Review of analytical methods for prospective cohort studies using time to event data: Single studies and implications for meta-analysis
    • Bennett DA (2003) Review of analytical methods for prospective cohort studies using time to event data: single studies and implications for meta-analysis. Stat Methods Med Res 12: 297-319
    • (2003) Stat Methods Med Res , vol.12 , pp. 297-319
    • Bennett, D.A.1
  • 10
    • 0142155633 scopus 로고    scopus 로고
    • Markers of prognosis and response to treatment: Ready for clinical use in oncology? A biostatistician's viewpoint
    • Boracchi P, Biganzoli E (2003) Markers of prognosis and response to treatment: ready for clinical use in oncology? A biostatistician's viewpoint. Int J Biol Markers 18: 65-69
    • (2003) Int J Biol Markers , vol.18 , pp. 65-69
    • Boracchi, P.1    Biganzoli, E.2
  • 11
    • 0036384579 scopus 로고    scopus 로고
    • Prognostic factors in non-small cell lung cancer: A decade of progress
    • Brundage MD, Davies D, Mackillop WJ (2002) Prognostic factors in non-small cell lung cancer: a decade of progress. Chest 122: 1037-1057
    • (2002) Chest , vol.122 , pp. 1037-1057
    • Brundage, M.D.1    Davies, D.2    Mackillop, W.J.3
  • 12
    • 0031763090 scopus 로고    scopus 로고
    • Specimen banks for cancer prognostic factor research
    • Burke HB, Henson DE (1998) Specimen banks for cancer prognostic factor research. Arch Pathol Lab Med 122: 871-874
    • (1998) Arch Pathol Lab Med , vol.122 , pp. 871-874
    • Burke, H.B.1    Henson, D.E.2
  • 13
    • 3343019343 scopus 로고    scopus 로고
    • Missing covariate data within cancer prognostic studies: A review of current reporting and proposed guidelines
    • Burton A, Altman DG (2004) Missing covariate data within cancer prognostic studies: a review of current reporting and proposed guidelines. Br J Cancer 91: 4-8
    • (2004) Br J Cancer , vol.91 , pp. 4-8
    • Burton, A.1    Altman, D.G.2
  • 14
    • 22144471920 scopus 로고    scopus 로고
    • Cardis E, Vrijheid M, Blettner M, Gilbert E, Hakama M, Hill C, Howe G, Kaldor J, Muirhead CR, Schubauer-Berigan M, Yoshimura T, Bermann F, Cowper G, Fix J, Hacker C, Heinmiller B, Marshall M, Thierry-Chef I, Utterback D, Ahn YO, Amoros E, Ashmore P, Auvinen A, Bae JM, Solano JB, Biau A, Combalot E, Deboodt P, Diez Sacristan A, Eklof M, Engels H, Engholm G, Gulis G, Habib R, Holan K, Hyvonen H, Kerekes A, Kurtinaitis J, Malker H, Martuzzi M, Mastauskas A, Monnet A, Moser M, Pearce MS, Richardson DB, Rodriguez-Artalejo F, Rogel A, Tardy H, Telle-Lamberton M, Turai I, Usel M, Veress K (2005) Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries. BMJ 331: 77
    • Cardis E, Vrijheid M, Blettner M, Gilbert E, Hakama M, Hill C, Howe G, Kaldor J, Muirhead CR, Schubauer-Berigan M, Yoshimura T, Bermann F, Cowper G, Fix J, Hacker C, Heinmiller B, Marshall M, Thierry-Chef I, Utterback D, Ahn YO, Amoros E, Ashmore P, Auvinen A, Bae JM, Solano JB, Biau A, Combalot E, Deboodt P, Diez Sacristan A, Eklof M, Engels H, Engholm G, Gulis G, Habib R, Holan K, Hyvonen H, Kerekes A, Kurtinaitis J, Malker H, Martuzzi M, Mastauskas A, Monnet A, Moser M, Pearce MS, Richardson DB, Rodriguez-Artalejo F, Rogel A, Tardy H, Telle-Lamberton M, Turai I, Usel M, Veress K (2005) Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries. BMJ 331: 77
  • 16
    • 33846978784 scopus 로고    scopus 로고
    • Critical review of published microarray studies for cancer outcome and guidelines on statistical analysis and reporting
    • Dupuy A, Simon RM (2007) Critical review of published microarray studies for cancer outcome and guidelines on statistical analysis and reporting. J Natl Cancer Inst 99: 147-157
    • (2007) J Natl Cancer Inst , vol.99 , pp. 147-157
    • Dupuy, A.1    Simon, R.M.2
  • 23
    • 33645642434 scopus 로고    scopus 로고
    • Evaluation of the quality of prognosis studies in systematic reviews
    • Hayden JA, Cote P, Bombardier C (2006) Evaluation of the quality of prognosis studies in systematic reviews. Ann Intern Med 144: 427-437
    • (2006) Ann Intern Med , vol.144 , pp. 427-437
    • Hayden, J.A.1    Cote, P.2    Bombardier, C.3
  • 24
    • 42749087941 scopus 로고    scopus 로고
    • Hayden JA, Côté P, Steenstra IA, Bombardier C, QUIPS-LBP Working Group (2008) Identifying phases of investigation helps planning, appraising, and applying the results of explanatory prognosis studies. J Clin Epidemiol 61: 552-560
    • Hayden JA, Côté P, Steenstra IA, Bombardier C, QUIPS-LBP Working Group (2008) Identifying phases of investigation helps planning, appraising, and applying the results of explanatory prognosis studies. J Clin Epidemiol 61: 552-560
  • 25
    • 44049098957 scopus 로고    scopus 로고
    • A model citizen? Is tamoxifen more effective than aromatase inhibitors if we pick the right patients?
    • Hayes DF, Stearns V, Rae J, Flockhart D (2008) A model citizen? Is tamoxifen more effective than aromatase inhibitors if we pick the right patients? J Natl Cancer Inst 100: 610-613
    • (2008) J Natl Cancer Inst , vol.100 , pp. 610-613
    • Hayes, D.F.1    Stearns, V.2    Rae, J.3    Flockhart, D.4
  • 26
    • 33750728067 scopus 로고    scopus 로고
    • Prognosis research: Why is Dr. Lydgate still waiting?
    • Hemingway H (2006) Prognosis research: why is Dr. Lydgate still waiting? J Clin Epidemiol 59: 1229-1238
    • (2006) J Clin Epidemiol , vol.59 , pp. 1229-1238
    • Hemingway, H.1
  • 27
    • 34250855575 scopus 로고    scopus 로고
    • Improving prognosis research: Standards primary, secondary, and tertiary
    • Hemingway H (2007) Improving prognosis research: standards primary, secondary, and tertiary. J Clin Epidemiol 60: 865-866
    • (2007) J Clin Epidemiol , vol.60 , pp. 865-866
    • Hemingway, H.1
  • 28
    • 29544445940 scopus 로고    scopus 로고
    • Individual survival time prediction using statistical models
    • Henderson R, Keiding N (2005) Individual survival time prediction using statistical models. J Med Ethics 31: 703-706
    • (2005) J Med Ethics , vol.31 , pp. 703-706
    • Henderson, R.1    Keiding, N.2
  • 30
    • 33747193146 scopus 로고    scopus 로고
    • On statistical approaches for the multivariable analysis of prognostic factor studies
    • Auget J-L, Balakrishnan N, Mesbah M, Molenberghs G eds, pp, Birkhäuser: Boston
    • Holländer N, Sauerbrei W (2006) On statistical approaches for the multivariable analysis of prognostic factor studies. In Advances in Statistical Methods for the Health Sciences. Auget J-L, Balakrishnan N, Mesbah M, Molenberghs G (eds), pp 19-38. Birkhäuser: Boston
    • (2006) Advances in Statistical Methods for the Health Sciences , pp. 19-38
    • Holländer, N.1    Sauerbrei, W.2
  • 31
    • 0033517574 scopus 로고    scopus 로고
    • Time to register randomised trials. The case is now unanswerable
    • Horton R, Smith R (1999) Time to register randomised trials. The case is now unanswerable. BMJ 319: 865-866
    • (1999) BMJ , vol.319 , pp. 865-866
    • Horton, R.1    Smith, R.2
  • 32
    • 0036682217 scopus 로고    scopus 로고
    • Commentary: Meta-analysis of individual participants' data in genetic epidemiology
    • Ioannidis JP, Rosenberg PS, Goedert JJ, O'Brien TR (2002) Commentary: meta-analysis of individual participants' data in genetic epidemiology. Am J Epidemiol 156: 204-210
    • (2002) Am J Epidemiol , vol.156 , pp. 204-210
    • Ioannidis, J.P.1    Rosenberg, P.S.2    Goedert, J.J.3    O'Brien, T.R.4
  • 33
    • 64949133172 scopus 로고    scopus 로고
    • Kattan MW (2003) Judging new markers by their ability to improve predictive accuracy. J Natl Cancer Inst 95: 634-635 Katz EM, Kattan MW (2005) How to judge a tumor marker. Nat Clin Pract Oncol 2: 482-483
    • Kattan MW (2003) Judging new markers by their ability to improve predictive accuracy. J Natl Cancer Inst 95: 634-635 Katz EM, Kattan MW (2005) How to judge a tumor marker. Nat Clin Pract Oncol 2: 482-483
  • 34
    • 36048930159 scopus 로고    scopus 로고
    • Almost all articles on cancer prognostic markers report statistically significant results
    • Kyzas PA, Denaxa-Kyza D, Ioannidis JP (2007a) Almost all articles on cancer prognostic markers report statistically significant results. Eur J Cancer 43: 2559-2579
    • (2007) Eur J Cancer , vol.43 , pp. 2559-2579
    • Kyzas, P.A.1    Denaxa-Kyza, D.2    Ioannidis, J.P.3
  • 35
    • 33847731795 scopus 로고    scopus 로고
    • Quality of reporting of cancer prognostic marker studies: Association with reported prognostic effect
    • Kyzas PA, Denaxa-Kyza D, Ioannidis JP (2007b) Quality of reporting of cancer prognostic marker studies: association with reported prognostic effect. J Natl Cancer Inst 99: 236-243
    • (2007) J Natl Cancer Inst , vol.99 , pp. 236-243
    • Kyzas, P.A.1    Denaxa-Kyza, D.2    Ioannidis, J.P.3
  • 36
    • 64949187660 scopus 로고    scopus 로고
    • Kyzas PA, Loizou KT, Ioannidis JP (2005) Selective reporting biases in cancer prognostic factor studies. J Natl Cancer Inst 97: 1043-1055 Look MP, van Putten WL, Duffy MJ, Harbeck N, Christensen IJ, Thomssen C, Kates R, Spyratos F, Ferno M, Eppenberger-Castori S, Sweep CG, Ulm K, Peyrat JP, Martin PM, Magdelenat H, Brunner N, Duggan C, Lisboa BW, Bendahl PO, Quillien V, Daver A, Ricolleau G, Meijer-van Gelder ME, Manders P, Fiets WE, Blankenstein MA, Broet P, Romain S, Daxenbichler G, Windbichler G, Cufer T, Borstnar S, Kueng W, Beex LV, Klijn JG, O'Higgins N, Eppenberger U, Janicke F, Schmitt M, Foekens JA (2002) Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst 94: 116-128
    • Kyzas PA, Loizou KT, Ioannidis JP (2005) Selective reporting biases in cancer prognostic factor studies. J Natl Cancer Inst 97: 1043-1055 Look MP, van Putten WL, Duffy MJ, Harbeck N, Christensen IJ, Thomssen C, Kates R, Spyratos F, Ferno M, Eppenberger-Castori S, Sweep CG, Ulm K, Peyrat JP, Martin PM, Magdelenat H, Brunner N, Duggan C, Lisboa BW, Bendahl PO, Quillien V, Daver A, Ricolleau G, Meijer-van Gelder ME, Manders P, Fiets WE, Blankenstein MA, Broet P, Romain S, Daxenbichler G, Windbichler G, Cufer T, Borstnar S, Kueng W, Beex LV, Klijn JG, O'Higgins N, Eppenberger U, Janicke F, Schmitt M, Foekens JA (2002) Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst 94: 116-128
  • 38
    • 24944452378 scopus 로고    scopus 로고
    • McShane LM, Altman DG, Sauerbrei W (2005a) Identification of clinically useful cancer prognostic factors: what are we missing? J Natl Cancer Inst 97: 1023-1025 McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM (2005b) REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer 93: 387-391
    • McShane LM, Altman DG, Sauerbrei W (2005a) Identification of clinically useful cancer prognostic factors: what are we missing? J Natl Cancer Inst 97: 1023-1025 McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM (2005b) REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer 93: 387-391
  • 40
    • 0035732988 scopus 로고    scopus 로고
    • Does age influence the behaviour of localized prostate cancer?
    • Parker CC, Gospodarowicz M, Warde P (2001) Does age influence the behaviour of localized prostate cancer? BJU Int 87: 629-637
    • (2001) BJU Int , vol.87 , pp. 629-637
    • Parker, C.C.1    Gospodarowicz, M.2    Warde, P.3
  • 41
    • 38849091997 scopus 로고    scopus 로고
    • Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond
    • Pencina MJ, D'Agostino SRB, D'Agostino JRB, Vasan RS (2008) Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 27: 157-172
    • (2008) Stat Med , vol.27 , pp. 157-172
    • Pencina, M.J.1    D'Agostino, S.R.B.2    D'Agostino, J.R.B.3    Vasan, R.S.4
  • 43
    • 2342571696 scopus 로고    scopus 로고
    • Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker
    • Pepe MS, Janes H, Longton G, Leisenring W, Newcomb P (2004) Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker. Am J Epidemiol 159: 882-890
    • (2004) Am J Epidemiol , vol.159 , pp. 882-890
    • Pepe, M.S.1    Janes, H.2    Longton, G.3    Leisenring, W.4    Newcomb, P.5
  • 44
    • 5444269445 scopus 로고    scopus 로고
    • Meta-analyses based on abstracted data: A step in the right direction, but only a first step
    • Piedbois P, Buyse M (2004) Meta-analyses based on abstracted data: a step in the right direction, but only a first step. J Clin Oncol 22: 3839-3841
    • (2004) J Clin Oncol , vol.22 , pp. 3839-3841
    • Piedbois, P.1    Buyse, M.2
  • 45
    • 35848962931 scopus 로고    scopus 로고
    • How to improve reliability and efficiency of research about molecular markers: Roles of phases, guidelines, and study design
    • Ransohoff R (2007) How to improve reliability and efficiency of research about molecular markers: roles of phases, guidelines, and study design. J Clin Epidemiol 60: 1205-1219
    • (2007) J Clin Epidemiol , vol.60 , pp. 1205-1219
    • Ransohoff, R.1
  • 46
    • 48449097132 scopus 로고    scopus 로고
    • Standard Operating Procedures, ethical and legal regulations in BTB (Brain/Tissue/Bio) banking: What is still missing?
    • Ravid R (2008) Standard Operating Procedures, ethical and legal regulations in BTB (Brain/Tissue/Bio) banking: what is still missing? Cell Tissue Bank 9: 121-137
    • (2008) Cell Tissue Bank , vol.9 , pp. 121-137
    • Ravid, R.1
  • 47
    • 47549099190 scopus 로고    scopus 로고
    • Reporting bias in diagnostic and prognostic studies: Time for action
    • Rifai N, Altman DG, Bossuyt PM (2008) Reporting bias in diagnostic and prognostic studies: time for action. Clin Chem 54: 1101-1103
    • (2008) Clin Chem , vol.54 , pp. 1101-1103
    • Rifai, N.1    Altman, D.G.2    Bossuyt, P.M.3
  • 48
    • 33747175284 scopus 로고    scopus 로고
    • Where next for evidence synthesis of prognostic marker studies? Improving the quality and reporting of primary studies to facilitate clinically relevant evidence-based results
    • Auget J-L, Balakrishnan N, Mesbah M, Molenberghs G eds, pp, Birkhäuser: Boston
    • Riley RD, Abrams KR, Lambert PC, Sutton AJ, Altman DG (2006a) Where next for evidence synthesis of prognostic marker studies? Improving the quality and reporting of primary studies to facilitate clinically relevant evidence-based results. In Advances in Statistical Methods for the Health Sciences. Auget J-L, Balakrishnan N, Mesbah M, Molenberghs G (eds), pp 39-58. Birkhäuser: Boston
    • (2006) Advances in Statistical Methods for the Health Sciences , pp. 39-58
    • Riley, R.D.1    Abrams, K.R.2    Lambert, P.C.3    Sutton, A.J.4    Altman, D.G.5
  • 49
    • 0038485778 scopus 로고    scopus 로고
    • Reporting of prognostic markers: Current problems and development of guidelines for evidence-based practice in the future
    • Riley RD, Abrams KR, Sutton AJ, Lambert PC, Jones DR, Heney D, Burchill SA (2003) Reporting of prognostic markers: current problems and development of guidelines for evidence-based practice in the future. Br J Cancer 88: 1191-1198
    • (2003) Br J Cancer , vol.88 , pp. 1191-1198
    • Riley, R.D.1    Abrams, K.R.2    Sutton, A.J.3    Lambert, P.C.4    Jones, D.R.5    Heney, D.6    Burchill, S.A.7
  • 52
    • 85058203703 scopus 로고    scopus 로고
    • Combining individual patient data and aggregate data in evidence synthesis: A systematic review identified current practice and possible methods
    • Riley RD, Look MP, Simmonds MC (2007a) Combining individual patient data and aggregate data in evidence synthesis: a systematic review identified current practice and possible methods. J Clin Epidemiol 60: 431-439
    • (2007) J Clin Epidemiol , vol.60 , pp. 431-439
    • Riley, R.D.1    Look, M.P.2    Simmonds, M.C.3
  • 54
    • 7044250891 scopus 로고    scopus 로고
    • Sensitivity analyses allowed more appropriate and reliable meta-analysis conclusions for multiple outcomes when missing data was present
    • Riley RD, Sutton AJ, Abrams KR, Lambert PC (2004b) Sensitivity analyses allowed more appropriate and reliable meta-analysis conclusions for multiple outcomes when missing data was present. J Clin Epidemiol 57: 911-924
    • (2004) J Clin Epidemiol , vol.57 , pp. 911-924
    • Riley, R.D.1    Sutton, A.J.2    Abrams, K.R.3    Lambert, P.C.4
  • 55
    • 32144444743 scopus 로고    scopus 로고
    • Rothstein HR, Sutton AJ, Borenstein M eds, Wiley: Chichester
    • Rothstein HR, Sutton AJ, Borenstein M (eds) (2005) Publication Bias in Meta-Analysis. Wiley: Chichester
    • (2005) Publication Bias in Meta-Analysis
  • 56
    • 31344435149 scopus 로고    scopus 로고
    • Dichotomizing continuous predictors in multiple regression: A bad idea
    • Royston P, Altman DG, Sauerbrei W (2006) Dichotomizing continuous predictors in multiple regression: a bad idea. Stat Med 25: 127-141
    • (2006) Stat Med , vol.25 , pp. 127-141
    • Royston, P.1    Altman, D.G.2    Sauerbrei, W.3
  • 58
    • 15744374441 scopus 로고    scopus 로고
    • Clinical trial designs for predictive marker validation in cancer treatment trials
    • Sargent DJ, Conley BA, Allegra C, Collette L (2005) Clinical trial designs for predictive marker validation in cancer treatment trials. J Clin Oncol 23: 2020-2027
    • (2005) J Clin Oncol , vol.23 , pp. 2020-2027
    • Sargent, D.J.1    Conley, B.A.2    Allegra, C.3    Collette, L.4
  • 59
    • 0033426505 scopus 로고    scopus 로고
    • The use of resampling methods to simplify regression models in medical statistics
    • Sauerbrei W (1999) The use of resampling methods to simplify regression models in medical statistics. Appl Stat 48: 313-329
    • (1999) Appl Stat , vol.48 , pp. 313-329
    • Sauerbrei, W.1
  • 60
    • 16644400192 scopus 로고    scopus 로고
    • Prognostic factors - confusion caused by bad quality of design, analysis and reporting of many studies
    • Bier H ed, Karger: Basel
    • Sauerbrei W (2005) Prognostic factors - confusion caused by bad quality of design, analysis and reporting of many studies. In Current Research in Head and Neck Cancer: Advances in Oto-Rhino-Laryngology. Bier H (ed), Vol. 62, pp 184-200. Karger: Basel
    • (2005) Current Research in Head and Neck Cancer: Advances in Oto-Rhino-Laryngology , vol.62 , pp. 184-200
    • Sauerbrei, W.1
  • 61
    • 33747177089 scopus 로고    scopus 로고
    • Evidence-based assessment and application of prognostic markers: The long way from single studies to meta-analysis
    • Sauerbrei W, Holländer N, Riley RD, Altman DG (2006) Evidence-based assessment and application of prognostic markers: the long way from single studies to meta-analysis. Commun Stat 35: 1333-1342
    • (2006) Commun Stat , vol.35 , pp. 1333-1342
    • Sauerbrei, W.1    Holländer, N.2    Riley, R.D.3    Altman, D.G.4
  • 62
    • 0031036070 scopus 로고    scopus 로고
    • Validation of existing and development of new prognostic classification schemes in node negative breast cancer. German Breast Cancer Study Group
    • Sauerbrei W, Hübner K, Schmoor C, Schumacher M (1997) Validation of existing and development of new prognostic classification schemes in node negative breast cancer. German Breast Cancer Study Group. Breast Cancer Res Treat 42: 149-163
    • (1997) Breast Cancer Res Treat , vol.42 , pp. 149-163
    • Sauerbrei, W.1    Hübner, K.2    Schmoor, C.3    Schumacher, M.4
  • 63
    • 38849176100 scopus 로고    scopus 로고
    • Selection of important variables and determination of functional form for continuous predictors in multivariable model building
    • Sauerbrei W, Royston P, Binder H (2007) Selection of important variables and determination of functional form for continuous predictors in multivariable model building. Stat Med 26: 5512-5528
    • (2007) Stat Med , vol.26 , pp. 5512-5528
    • Sauerbrei, W.1    Royston, P.2    Binder, H.3
  • 65
    • 0033673208 scopus 로고    scopus 로고
    • p53 immuno- histochemistry as a prognostic marker in bladder cancer. Playground for urology scientists?
    • Schmitz-Dräger BJ, Goebell PJ, Ebert T, Fradet Y (2000) p53 immuno- histochemistry as a prognostic marker in bladder cancer. Playground for urology scientists? Eur Urol 38: 691-699
    • (2000) Eur Urol , vol.38 , pp. 691-699
    • Schmitz-Dräger, B.J.1    Goebell, P.J.2    Ebert, T.3    Fradet, Y.4
  • 67
    • 0034728368 scopus 로고    scopus 로고
    • On the misuse of artificial neural networks for prognostic and diagnostic classification in oncology
    • Schwarzer G, Vach W, Schumacher M (2000) On the misuse of artificial neural networks for prognostic and diagnostic classification in oncology. Stat Med 19: 541-561
    • (2000) Stat Med , vol.19 , pp. 541-561
    • Schwarzer, G.1    Vach, W.2    Schumacher, M.3
  • 68
    • 0023008125 scopus 로고
    • Publication bias: The case for an international registry of clinical trials
    • Simes RJ (1986) Publication bias: the case for an international registry of clinical trials. J Clin Oncol 4: 1529-1541
    • (1986) J Clin Oncol , vol.4 , pp. 1529-1541
    • Simes, R.J.1
  • 69
    • 0038315699 scopus 로고    scopus 로고
    • Evaluating prognostic factor studies
    • Gospodarowicz MK ed, pp, New York: Wiley-Liss
    • Simon R (2001) Evaluating prognostic factor studies. In Prognostic Factors in Cancer. Gospodarowicz MK (ed), pp 49-56. New York: Wiley-Liss
    • (2001) Prognostic Factors in Cancer , pp. 49-56
    • Simon, R.1
  • 70
    • 0028318390 scopus 로고
    • Statistical aspects of prognostic factor studies in oncology
    • Simon R, Altman DG (1994) Statistical aspects of prognostic factor studies in oncology. Br J Cancer 69: 979-985
    • (1994) Br J Cancer , vol.69 , pp. 979-985
    • Simon, R.1    Altman, D.G.2
  • 71
    • 0035859525 scopus 로고    scopus 로고
    • Systematic reviews in health care: Investigating and dealing with publication and other biases in meta-analysis
    • Sterne JA, Egger M, Smith GD (2001) Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis. BMJ 323: 101-105
    • (2001) BMJ , vol.323 , pp. 101-105
    • Sterne, J.A.1    Egger, M.2    Smith, G.D.3
  • 72
    • 0036167948 scopus 로고    scopus 로고
    • To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data
    • Stewart LA, Tierney JF (2002) To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data. Eval Health Prof 25: 76-97
    • (2002) Eval Health Prof , vol.25 , pp. 76-97
    • Stewart, L.A.1    Tierney, J.F.2
  • 74
    • 33646353175 scopus 로고    scopus 로고
    • The challenges of gene expression microarrays for the study of human cancer
    • Tinker AV, Boussioutas A, Bowtell DD (2006) The challenges of gene expression microarrays for the study of human cancer. Cancer Cell 9: 333-339
    • (2006) Cancer Cell , vol.9 , pp. 333-339
    • Tinker, A.V.1    Boussioutas, A.2    Bowtell, D.D.3
  • 75
    • 17844371350 scopus 로고    scopus 로고
    • Investigating heterogeneity in an individual patient data meta-analysis of time to event outcomes
    • Tudur-Smith C, Williamson PR, Marson AG (2005) Investigating heterogeneity in an individual patient data meta-analysis of time to event outcomes. Stat Med 24: 1307-1319
    • (2005) Stat Med , vol.24 , pp. 1307-1319
    • Tudur-Smith, C.1    Williamson, P.R.2    Marson, A.G.3
  • 76
    • 38349049478 scopus 로고    scopus 로고
    • Selective publication of antidepressant trials and its influence on apparent efficacy
    • Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R (2008) Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 358: 252-260
    • (2008) N Engl J Med , vol.358 , pp. 252-260
    • Turner, E.H.1    Matthews, A.M.2    Linardatos, E.3    Tell, R.A.4    Rosenthal, R.5
  • 77
    • 0028182719 scopus 로고
    • Prognostic factors in malignant mesothelioma: Where do we go from here?
    • Van Meerbeeck JP (1994) Prognostic factors in malignant mesothelioma: where do we go from here? Eur Respir J 7: 1029-1031
    • (1994) Eur Respir J , vol.7 , pp. 1029-1031
    • Van Meerbeeck, J.P.1
  • 78
    • 33750905259 scopus 로고    scopus 로고
    • Decision curve analysis: A novel method for evaluating prediction models
    • Vickers AJ, Elkin EB (2006) Decision curve analysis: a novel method for evaluating prediction models. Med Decis Making 26: 565-574
    • (2006) Med Decis Making , vol.26 , pp. 565-574
    • Vickers, A.J.1    Elkin, E.B.2
  • 79
    • 0034728361 scopus 로고    scopus 로고
    • Prognosis - what does the clinician associate with this notion?
    • Windeler J (2000) Prognosis - what does the clinician associate with this notion? Stat Med 19: 425-430
    • (2000) Stat Med , vol.19 , pp. 425-430
    • Windeler, J.1
  • 80
    • 84971357232 scopus 로고
    • Commentary: Prognostic models: clinically useful or quickly forgotten?
    • Wyatt J, Altman DG (1995) Commentary: Prognostic models: clinically useful or quickly forgotten? BMJ 311: 1539-1541
    • (1995) BMJ , vol.311 , pp. 1539-1541
    • Wyatt, J.1    Altman, D.G.2


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