Monitoring of gliomas in vivo by diffusion MRI and 1H MRS during gene therapy-induced apoptosis: Interrelationships between water diffusion and mobile lipids

NMR in Biomedicine

Volumn 22, Issue 3, 2009, Pages 272-279

  Lilimatainen, Timo ^a,b   Hakumäki, Juhana M ^c   Kauppinen, Risto A ^d   Ala Korpela, Mika ^e,f,g  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

^e AALTO UNIVERSITY   (Finland)

^f FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^g HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Apoptosis; Apparent diffusion coefficient; Diffusion MRI; Gene therapy; Glioma; In vivo 1H MRS; Mobile lipids; Water diffusion

Indexed keywords

ANTIVIRAL AGENTS; CELL DEATH; DIFFUSION IN LIQUIDS; DISEASES; DRUG PRODUCTS; FATTY ACIDS; GENE THERAPY; MAGNETIC RESONANCE IMAGING; NONINVASIVE MEDICAL PROCEDURES; SHRINKAGE; SURFACE DIFFUSION; TISSUE ENGINEERING; TUMORS;

APPARENT DIFFUSION COEFFICIENT; DIFFUSION MRIS; GLIOMA; IN-VIVO; WATER DIFFUSION;

LIPIDS;

CHOLESTEROL; FATTY ACID; GANCICLOVIR; THYMIDINE KINASE; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CELL DENSITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DRUG RESPONSE; FEMALE; GENETIC TRANSFECTION; GLIOMA; HISTOPATHOLOGY; IMAGE ANALYSIS; IN VIVO STUDY; LIPID COMPOSITION; LIPID STORAGE; LIPID TRANSPORT; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RELIABILITY; SUICIDE GENE THERAPY; TUMOR MODEL; TUMOR VOLUME; WATER TRANSPORT; ANIMAL; CELL COUNT; GENE THERAPY; LIPID METABOLISM; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY;

HERPES; RODENTIA;

ANIMALS; APOPTOSIS; CELL COUNT; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; GENE THERAPY; GLIOMA; LIPID METABOLISM; MAGNETIC RESONANCE SPECTROSCOPY; RATS; WATER;

EID: 64949139707     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1320     Document Type: Article

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