Water Diffusion in a Rat Glioma during Ganciclovir-Thymidine Kinase Gene Therapy-Induced Programmed Cell Death in Vivo: Correlation with Cell Density

Journal of Magnetic Resonance Imaging

Volumn 19, Issue 4, 2004, Pages 389-396

  Valonen, Piia K ^a   Lehtimäki, Kimmo K ^a   Väisänen, Tuula H ^a   Kettunen, Mikko I ^a   Gröhn, Olli H J ^a   Ylä Herttuala, Seppo ^a   Kauppinen, Risto A ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cell density; Diffusion; Gene therapy; Glioma; Magnetic resonance imaging; Programmed cell death

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; APPARATUS; ARTICLE; CELL COUNT; CELL DENSITY; DIFFUSION COEFFICIENT; DIFFUSION TENSOR IMAGING; DIFFUSION WEIGHTED IMAGING; GENE THERAPY; GLIOMA; HISTOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BODY WATER; BRAIN NEOPLASMS; CELL COUNT; FEMALE; GANCICLOVIR; GENE THERAPY; GLIOMA; HERPES SIMPLEX; MAGNETIC RESONANCE SPECTROSCOPY; RATS; RATS, INBRED STRAINS; THYMIDINE KINASE; TRANSFECTION;

EID: 1842433654     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.20026     Document Type: Article

References (37)

1. 2-weighted MRI and spectroscopy. Magn Reson Med 1990;14:330-346.
2. Baird AE, Warach S. Magnetic resonance imaging of acute stroke. J Cereb Blood Flow Metab 1998;18:583-609.
3. Alsop DC, Murai H, Detre JA, McIntosh TK, Smith DH. Detection of acute pathologic changes following experimental traumatic brain injury using diffusion-weighted magnetic resonance imaging. J Neurotrauma 1996;13:515-521.
4. Kauppinen RA. Monitoring cytotoxic tumour treatment response by diffusion magnetic resonance imaging and proton spectroscopy. NMR Biomed 2002;15:6-17.
5. Zhao M, Pipe JG, Bonnett J, Evelhoch JL. Early detection of treatment response by diffusion-weighted 1H-NMR spectroscopy in a murine tumour in vivo. Br J Cancer 1996;73:61-64.
6. Ross BD, Kim B, Davidson BL. Assessment of ganciclovir toxicity to experimental intracranial gliomas following recombinant adenoviral-mediated transfer of the herpes simplex virus thymidine kinase gene by magnetic resonance imaging and proton magnetic resonance spectroscopy. Clin Cancer Res 1995;1:651-657.
7. Poptani H, Puumalainen A-M, Gröhn OHJ, et al. Monitoring thymidine kinase and ganciclovir-induced changes in rat malignat glioma in vivo by nuclear magnetic resonance imaging. Cancer Gene Ther 1998;5:101-109.
8. Chenevert TL, Stegman LD, Taylor JM, Robertson PL, Greenberg HS, Rehemtulla A, Ross BD. Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst 2000;92:2029-2036.
9. Mardor Y, Roth Y, Lidar Z, et al. Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging. Cancer Res 2001;61:4971-4973.
10. Verheul B, Balazs R, van der Sprenkel JWB, et al. Comparison of diffusion-weighted MRI with changes in cell volume in a rat model of brain injury. NMR Biomed 1994;7:96-100.
11. 133Cs NMR. Magn Reson Med 1996;35:329-335.
12. 19F NMR. Magn Reson Med 1998;40:1-13.
13. Gupta RK, Sinha U, Cloughesy TF, Alger JR. Inverse correlation between choline magnetic resonance spectroscopy signal intensity and the apparent diffusion coefficient in human glioma. Magn Reson Med 1999;41:2-7.
14. Galons JP, Altbach MI, Paine-Murrieta GD, Taylor CW, Gillies RJ. Early increases in breast tumor xenograft water mobility in response to paclitaxel therapy detected by non-invasive diffusion magnetic resonance imaging. Neoplasia 1999;1:113-117.
15. Sandmair AM, Loimas S, Puranen P, et al. Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Hum Gene Ther 2000;11:2197-2205.
16. 1 in the rotating frame. Cancer Gene Ther 2002;9:338-345.
17. Garwood M, Ke Y. Symmetric pulses to induce arbitrary flip angles with compensation for RF inhomogeneity and resonance offsets. J Magn Reson 1991;94:511-525.
18. Mori S, van Zijl PCM. Diffusion weighting by the trace of the diffusion tensor within a single scan. Magn Reson Med 1995;33:41-52.
19. Gruetter R. Automatic, localized in vivo adjustment of all first- and second-order shim coils. Magn Reson Med 1993;29:804-811.
20. 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn Reson Med 1999;41:649-656.
21. 1p. J Cereb Blood Flow Metab 2000;20:1457-1466.
22. Lee JH, Springer Jr CS. Effects of equilibrium exchange on diffusion-weighted NMR signals: the diffusigraphic "shutter-speed." Magn Reson Med 2003;49:450-458.
23. 1H NMR spectroscopy. NMR Biomed 1998;11:11-18.
24. 2. J Cereb Blood Flow Metab 1998;18:911-920.
25. 2 during focal cerebral ischemia in the rat studied at 8.5 T. Magn Reson Med 1999;41:479-485.
26. Mori S, Frederiksen K, van Zijl PC, et al. Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging. Ann Neurol 2002;51:377-380.
27. Cameron IL, Kanal KM, Keener CR, Fullerton GD. A mechanistic view of the non-ideal osmotic and motional behavior of intracellular water. Cell Biol Int 1997;21:99-113.
28. Rusakov DA, Kullmann DM. Geometric and viscous components of the tortuosity of the extracellular space in the brain. Proc Natl Acad Sci USA 1998;95:8975-8980.
29. 1H NMR diffusion spectroscopy of BT4C rat glioma during thymidine kinase-mediated gene therapy in vivo: identification of apoptotic response. Cancer Res 1998;58:3791-3799.
30. Andrasko J. Water diffusion permeability of human erythrocytes studied by a pulsed gradient NMR technique. Biochim Biophys Acta 1976;428:304-311.
31. van Zijl PCM, Davis D, Moonen CTW. Diffusion spectroscopy in living systems. In: Gillies RJ, editor. NMR in physiology and biomedicine. San Diego: Academic Press; 1994. p 185-198.
32. Niendorf T, Dijkhuizen RM, Norris DG, van Lookeren Campagne M, Nicolay K. Biexponential diffusion attenuation in various states of brain tissue: implications for diffusion-weighted imaging. Magn Reson Med 1996;36:847-857.
33. Clark CA, Hedehus M, Moseley ME. In vivo mapping of the fast and slow diffusion tensors in human brain. Magn Reson Med 2002;47:623-638.
34. Eis M, Els T, Hoehn-Berlage M. High resolution quantitative relaxation and diffusion MRI of three different experimental brain tumors in rat. Magn Reson Med 1995;34:835-844.
35. Legler JM, Ries LA, Smith MA, et al. Cancer surveillance series: brain and other central nervous system cancers: recent trends in incidence and mortality. J Natl Cancer Inst 1999;91:1382-1390.
36. Olson JE, Janney CA, Rao RD, et al. The continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: a surveillance, epidemiology, and end results analysis. Cancer 2002;95:1504-1510.
37. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-1462.