Hepatitis B viral genotypes: Clinical relevance and molecular characteristics

Journal of Gastroenterology and Hepatology (Australia)

Volumn 17, Issue 6, 2002, Pages 643-650

  Kao, Jia Horng ^a,b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Chronic hepatitis; Clinical outcome; Genomic variability; Genotype; Hepatitis B virus; Hepatocellular carcinoma; Liver cirrhosis; Molecular epidemiology; Subtype; Superinfection

Indexed keywords

ANTIVIRUS AGENT; INTERFERON; LAMIVUDINE; VIRUS DNA;

ARTIFICIAL EMBOLISM; CANCER RECURRENCE; DISEASE SEVERITY; DISEASE TRANSMISSION; GENE MUTATION; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CELL CARCINOMA; LIVER DISEASE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; REVIEW; STOP CODON; SUPERINFECTION; TREATMENT OUTCOME; VIRUS GENOME; GENETICS; IMMUNOLOGY; LIVER CIRRHOSIS; LIVER TUMOR; VIROLOGY;

CARCINOMA, HEPATOCELLULAR; DNA, VIRAL; EMBOLIZATION, THERAPEUTIC; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; SUPERINFECTION;

EID: 0036019518     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2002.02737.x     Document Type: Review

References (61)

1. Overview of hepatitis B viruses
2. From hepatitis to hepatoma: Lessons from type B viral hepatitis
3. Natural history of chronic hepatitis B virus infection in adults with emphasis on the occurrence of cirrhosis and hepatocellular carcinoma
4. Acute exacerbation in chronic type B hepatitis: Comparison between HBeAg and antibody-positive patients
5. Acute exacerbations in Chinese patients with chronic hepatitis B virus (HBV) infection. Incidence, predisposing factors and etiology
6. Acute flares in chronic hepatitis B: The natural and unnatural history of an immunologically mediated liver disease
7. Genomic heterogeneity of hepatitis B virus in a 54 year old woman who contracted the infection through maternofetal transmission
8. Host-independent evolution and a genetic classification of the hepadnavirus family based on nucleotide sequences
9. Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene
10. A new genotype of hepatitis B virus: Complete genome and phylogenetic relatedness
11. Typing hepatitis B virus by homology in nucleotide sequence: Comparison of surface antigen subtypes
12. Geographical distribution of the subtype of hepatitis B surface antigen in Chinese
13. Clustering of different subtypes of hepatitis B surface antigen in families of patients with chronic liver diseases
14. Molecular epidemiology of hepatitis B viral serotypes and genotypes in Taiwan
15. Hepatitis B immunopathogenesis
16. Naturally occurring variants of hepatitis B virus
17. Clinical relevance of hepatitis B viral mutations
18. Relationship of HBsAg subtypes with HBeAg/anti-HBe status and chronic liver disease. Part I. Analysis of 1744 HBsAg carriers
19. Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers
20. Genotypes, nt 1858 variants, and geographic origin of hepatitis B virus: Large-scale analysis using a new genotyping method
21. Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns
22. Rapid and specific genotyping system for hepatitis B virus corresponding to six major genotypes by PCR using type-specific primers
23. Molecular characteristics of hepatitis B virus genotype A confer a higher response rate to interferon treatment
24. Serological detection of hepatitis B virus genotypes by ELISA with monoclonal antibodies to type-specific epitopes in the preS2-region product
25. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
26. Hepatitis B virus genotype distribution among chronic hepatitis B virus carriers in Shanghai, China
27. Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan
28. Hepatitis B virus genotypes and hepatocellular carcinoma in Japan: Reply
29. Correlation between hepatitis B virus infection and chronic liver disease in Okinawa
30. The woodchuck: An animal model for hepatitis B virus infection in man
31. Does hepatitis B virus (HBV) genotype influence the clinical outcome of HBV infection?
32. Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent
33. Acute exacerbation and superinfection in patients with chronic viral hepatitis
34. Clinical implications of mutations in the hepatitis B virus genome
35. Spontaneous reactivation of chronic hepatitis B virus infection
36. Reactivation of chronic hepatitis B virus infection by cancer chemotherapy
37. Lack of protective immunity against reinfection with hepatitis C virus
38. Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis
39. Mixed infections of hepatitis C virus as a factor in acute exacerbation of chronic type C hepatitis
40. Superinfection of homotypic virus in hepatitis C virus carriers: Studies on patients with posttransfusion hepatitis
41. Mixed genotypes infection with hepatitis D virus
42. Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: Correlation with viral persistence and disease severity
43. Acute exacerbations of chronic hepatitis B are rarely associated with superinfection of hepatitis B virus
44. The treatment of chronic viral hepatitis
45. Hepatitis B genotypes and the response to interferon therapy
46. Analysis of hepatitis B virus genotypes and pre-core region variability during interferon treatment of HBe antigen negative chronic hepatitis B
47. Management of hepatitis B: 2000 Summary of a workshop
48. 20-Fold increase in risk of lamivudine resistance in hepatitis B virus subtype adw
49. Hepatitis B viral genotypes and lamivudine resistance
50. Genotype may correlate with liver carcinogenesis and tumor characteristics in cirrhotic patients infected with hepatitis B virus subtype adw
51. Natural sero-conversion from hepatitis B e antigen to antibody among hepatitis B virus carriers in Okinawa Islands
52. Clinical and virological aspects of hepatitis B genotypes B and C-infected blood donors
53. A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C
54. Hepatitis B genotypes and precore/basal core promoter mutants in HBeAg-negative chronic hepatitis B
55. Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal
56. Hepatitis B virus infection: Precore mutants and its relation to viral genotypes and core mutations
57. Hepatitis B e antigen-negative chronic hepatitis B
58. Hepatitis B virus genomic sequence in the circulation of hepatocellular carcinoma patients: Comparative analysis of 40 full-length isolates
59. High prevalence of 1762(T) 1764(A) mutations in the basic core promoter of hepatitis B virus isolated from black Africans with hepatocellular carcinoma compared with asymptomatic carriers
60. The precore/core promoter mutant (T1762A1764) of hepatitis B virus: Clinical significance and an easy method for detection
61. Clinical relevance of hepatitis B viral genotypes: A case of déjà vu?