Synthetic cervical mucus formulation

Contraception

Volumn 66, Issue 2, 2002, Pages 137-140

  Burruano, Bríd T ^a   Schnaare, Roger L ^a,b   Malamud, Daniel ^b,c  

^a UNIVERSITY OF THE SCIENCES   (United States)

^b Adamis Pharmaceuticals Corporation   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cervical; Formulation; Guar gum; Mucus

Indexed keywords

BORIC ACID; BUFFER; GUAR GUM; MUCIN; PHOSPHATE;

ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; PH; PREFORMULATION; UTERINE CERVIX MUCUS; VISCOSITY;

BORATES; CERVIX MUCUS; CHEMISTRY, PHARMACEUTICAL; GALACTANS; HUMANS; HYDROGEN-ION CONCENTRATION; MANNANS; MUCINS; PLANT GUMS; VAGINAL CREAMS, FOAMS, AND JELLIES; VISCOSITY;

EID: 0036669711     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0010-7824(02)00336-0     Document Type: Article

References (19)

1. Marriot C., Gregory N.P. Mucus physiology and pathology. Lenaerts V., Gurny R., Bioadhesive drug delivery systems. 1990;1-24 CRC Press.
2. Katz D.F., Dunmire E.N. Cervical mucus problems and opportunities for drug delivery via the vagina and cervix. Adv Drug Delivery Rev. 11:1993;385-401.
3. Tang S., Garrett C., Baker H.W.G. Comparison of human cervical mucus and sperm media. Hum Reprod. 14:1999;2812-2817.
4. Karni Z., Polishuk W.Z., Adoni A., Diamant Y. Newtonian viscosity of the human cervical mucus during the menstrual cycle. Int J Fertil. 16:1971;185-188.
5. Ishijima S., Oshio S., Mohri H. Flagellar movement of human spermatozoa. Gamete Res. 13:1986;185-197.
6. Hwang S.H. Viscoelastic behavior of biological fluids. Chemical Engineering Dissertation. 1967;88-94 University of Pennsylvania.
7. Neuwinger J., Cooper T.J., Nuth U.A., Nieschlag E. Hyaluronic acid is a medium for human sperm migration tests. Hum Reprod. 6:1991;396-400.
8. Lorton S.P., Kummerfield H.L., Foote R.H. Polyacrylamide as a substitute for cervical mucus. Fert Steril. 35:1981;222-225.
9. Bisset D.L. Development of model human cervical mucus. Fert Steril. 33:1980;211-212.
10. Chrisp J.D. Gelled compositions containing galactomannan gums. 1967;. US Patent 3,301,723.
11. rd ed. 1992;p. 191 Academic Press, San Diego, CA.
12. rd ed. 2000;340-450 Apha, Washington, DC.
13. th ed. 1993;p. 147 Williams& Wilkins, Philadelphia, PA.
14. Parrott E.L. Pharmaceutical technology. 1970;Burgess Publishing Company, Minneapolis, MN. [chapter 11, p. 306].
15. Robinson G., Ross-Murphy S.B., Morris E.R. Viscosity-molecular weight relationships, intrinsic chain flexibility, dynamic solution properties of guar galactomannan. Carb Res. 107:1982;17-32.
16. Tuinier R., ten Grotenhuis E., deKruif C.G. The effect of depolymerised guar gum on the stability of skim milk. Food Hydrocolloids. 4:2001;1-7.
17. Lee W., Verdugo P., Blandau R.J., Gaddum-Rose P. Molecular arrangement of cervical mucus re-evaluation based on laser light-scattering spectroscopy . Gynecol Invest. 8:1977;254-266.
18. Ebring H. Kollidbeihefte. 44:1936;171.
19. Odeblad E. The functional structure of human cervical mucus. Acta Obst Gynec Scand. 47S:1968;47-79.