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Volumn 101, Issue 5, 2009, Pages 273-285

Geminin is partially localized to the centrosome and plays a role in proper centrosome duplication

Author keywords

Actin related protein 1 (Arp1); Centrosome; Dynamitin p50; Dynein dynactin complex; Geminin

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN; ACTIN RELATED PROTEIN 1; ADENOSINE TRIPHOSPHATE; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; GEMININ; PROTEIN P50; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; GMNN PROTEIN, HUMAN; HYDROXYUREA; MICROTUBULE ASSOCIATED PROTEIN; NR2F2 PROTEIN, HUMAN;

EID: 64749095806     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1042/BC20080109     Document Type: Article
Times cited : (25)

References (32)
  • 1
    • 0035997368 scopus 로고    scopus 로고
    • DNA replication in eukaryotic cells
    • Bell, S.P. and Dutta, A. (2002) DNA replication in eukaryotic cells. Annu. Rev. Biochem. 71, 333-374
    • (2002) Annu. Rev. Biochem , vol.71 , pp. 333-374
    • Bell, S.P.1    Dutta, A.2
  • 2
    • 8544283842 scopus 로고    scopus 로고
    • Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity
    • Benjamin, J.M., Torke, S.J., Demeler, B. and McGarry, T.J. (2004) Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity. J. Biol. Chem. 279, 45957-45968
    • (2004) J. Biol. Chem , vol.279 , pp. 45957-45968
    • Benjamin, J.M.1    Torke, S.J.2    Demeler, B.3    McGarry, T.J.4
  • 3
    • 0028989339 scopus 로고
    • Purification of an MCM-containing complex as a component of the DNA replication licensing system
    • Chong, J.P., Mahbubani, H.M., Khoo, C.Y. and Blow, J.J. (1995) Purification of an MCM-containing complex as a component of the DNA replication licensing system. Nature 375, 418-421
    • (1995) Nature , vol.375 , pp. 418-421
    • Chong, J.P.1    Mahbubani, H.M.2    Khoo, C.Y.3    Blow, J.J.4
  • 4
    • 0026686929 scopus 로고
    • Centractin is an actin homologue associated with the centrosome
    • Clark, S.W. and Meyer, D.I. (1992) Centractin is an actin homologue associated with the centrosome. Nature 359, 246-250
    • (1992) Nature , vol.359 , pp. 246-250
    • Clark, S.W.1    Meyer, D.I.2
  • 6
    • 0034069115 scopus 로고    scopus 로고
    • ARP1 in Golgi organisation and attachment of manchette microtubules to the nucleus during mammalian spermatogenesis
    • Fouquet, J., Kann, M., Soues, S. and Melki, R. (2000) ARP1 in Golgi organisation and attachment of manchette microtubules to the nucleus during mammalian spermatogenesis. J. Cell Sci. 113, 877-886
    • (2000) J. Cell Sci , vol.113 , pp. 877-886
    • Fouquet, J.1    Kann, M.2    Soues, S.3    Melki, R.4
  • 7
    • 0035873385 scopus 로고    scopus 로고
    • It takes two to tango': Understanding how centrosome duplication is regulated throughout the cell cycle
    • Hinchcliffe, E.H. and Sluder, G. (2001) 'It takes two to tango': understanding how centrosome duplication is regulated throughout the cell cycle. Genes Dev. 15, 1167-1181
    • (2001) Genes Dev , vol.15 , pp. 1167-1181
    • Hinchcliffe, E.H.1    Sluder, G.2
  • 8
    • 0035945356 scopus 로고    scopus 로고
    • Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
    • Howell, B.J., McEwen, B.F., Canman, J.C., Hoffman, D.B., Farrar, E.M., Rieder, C.L. and Salmon, E.D. (2001) Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J. Cell Biol. 155, 1159-1172
    • (2001) J. Cell Biol , vol.155 , pp. 1159-1172
    • Howell, B.J.1    McEwen, B.F.2    Canman, J.C.3    Hoffman, D.B.4    Farrar, E.M.5    Rieder, C.L.6    Salmon, E.D.7
  • 9
    • 0033789351 scopus 로고    scopus 로고
    • Dynactin increases the processivity of the cytoplasmic dynein motor
    • King, S.J. and Schroer, T.A. (2000) Dynactin increases the processivity of the cytoplasmic dynein motor. Nat. Cell Biol. 2, 20-24
    • (2000) Nat. Cell Biol , vol.2 , pp. 20-24
    • King, S.J.1    Schroer, T.A.2
  • 10
    • 2342442851 scopus 로고    scopus 로고
    • Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation
    • Liu, E., Li, X., Yan, F., Zhao, Q. and Wu, X. (2004) Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation. J. Biol. Chem. 279, 17283-17288
    • (2004) J. Biol. Chem , vol.279 , pp. 17283-17288
    • Liu, E.1    Li, X.2    Yan, F.3    Zhao, Q.4    Wu, X.5
  • 11
    • 33846534165 scopus 로고    scopus 로고
    • The APC/C inhibitor, Emi1, is essential for prevention of rereplication
    • Machida, Y.J. and Dutta, A. (2007) The APC/C inhibitor, Emi1, is essential for prevention of rereplication. Genes Dev. 21, 184-194
    • (2007) Genes Dev , vol.21 , pp. 184-194
    • Machida, Y.J.1    Dutta, A.2
  • 12
    • 0034611807 scopus 로고    scopus 로고
    • XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis
    • Maiorano, D., Moreau, J. and Mechali, M. (2000) XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis. Nature 404, 622-625
    • (2000) Nature , vol.404 , pp. 622-625
    • Maiorano, D.1    Moreau, J.2    Mechali, M.3
  • 13
    • 0032511148 scopus 로고    scopus 로고
    • Geminin, an inhibitor of DNA replication, is degraded during mitosis
    • McGarry, T.J. and Kirschner, M.W. (1998) Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell 93, 1043-1053
    • (1998) Cell , vol.93 , pp. 1043-1053
    • McGarry, T.J.1    Kirschner, M.W.2
  • 15
    • 0034658078 scopus 로고    scopus 로고
    • Formation of spindle poles by dynein/dynact-independent transport of NuMA
    • Merdes, A., Heald, R., Samejima, K., Earnshaw, W.C. and Cleveland, D.W. (2000) Formation of spindle poles by dynein/dynact-independent transport of NuMA. J. Cell Biol. 149, 851-862
    • (2000) J. Cell Biol , vol.149 , pp. 851-862
    • Merdes, A.1    Heald, R.2    Samejima, K.3    Earnshaw, W.C.4    Cleveland, D.W.5
  • 16
    • 0022960028 scopus 로고
    • Isolation of mammalian centrosomes
    • Mitchison, T.J. and Kirschner, M.W. (1986) Isolation of mammalian centrosomes. Methods Enzymol. 134, 261-268
    • (1986) Methods Enzymol , vol.134 , pp. 261-268
    • Mitchison, T.J.1    Kirschner, M.W.2
  • 17
    • 0036831681 scopus 로고    scopus 로고
    • Centrosome aberrations: Cause or consequence of cancer progression?
    • Nigg, E.A. (2002) Centrosome aberrations: cause or consequence of cancer progression? Nat. Rev. Cancer 2, 815-825
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 815-825
    • Nigg, E.A.1
  • 18
    • 0035976980 scopus 로고    scopus 로고
    • The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase
    • Nishitani, H., Taraviras, S., Lygerou, Z. and Nishimoto, T. (2001) The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase. J. Biol. Chem. 276, 44905-44911
    • (2001) J. Biol. Chem , vol.276 , pp. 44905-44911
    • Nishitani, H.1    Taraviras, S.2    Lygerou, Z.3    Nishimoto, T.4
  • 19
    • 0023205148 scopus 로고
    • Retrograde transport by the microtubule-associated protein MAP 1C
    • Paschal, B.M. and Vallee, R.B. (1987) Retrograde transport by the microtubule-associated protein MAP 1C. Nature 330, 181-183
    • (1987) Nature , vol.330 , pp. 181-183
    • Paschal, B.M.1    Vallee, R.B.2
  • 20
    • 3242739398 scopus 로고    scopus 로고
    • A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition
    • Saxena, S., Yuan, P., Dhar, S.K., Senga, T., Takeda, D., Robinson, H., Kornbluth, S., Swaminathan, K. and Dutta, A. (2004) A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. Mol. Cell 15, 245-258
    • (2004) Mol. Cell , vol.15 , pp. 245-258
    • Saxena, S.1    Yuan, P.2    Dhar, S.K.3    Senga, T.4    Takeda, D.5    Robinson, H.6    Kornbluth, S.7    Swaminathan, K.8    Dutta, A.9
  • 21
    • 0029891913 scopus 로고    scopus 로고
    • Actin-related protein 1 and cytoplasmic dynein-based motility: What's the connection?
    • Schroer, T.A., Bingham, J.B. and Gill, S.R. (1996) Actin-related protein 1 and cytoplasmic dynein-based motility: what's the connection? Trends Cell Biol. 6, 212-215
    • (1996) Trends Cell Biol , vol.6 , pp. 212-215
    • Schroer, T.A.1    Bingham, J.B.2    Gill, S.R.3
  • 23
    • 2442427423 scopus 로고    scopus 로고
    • Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding
    • Sugimoto, N., Tatsumi, Y., Tsurumi, T., Matsukage, A., Kiyono, T., Nishitani, H. and Fujita, M. (2004) Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. J. Biol. Chem. 279, 19691-19697
    • (2004) J. Biol. Chem , vol.279 , pp. 19691-19697
    • Sugimoto, N.1    Tatsumi, Y.2    Tsurumi, T.3    Matsukage, A.4    Kiyono, T.5    Nishitani, H.6    Fujita, M.7
  • 24
    • 31144472765 scopus 로고    scopus 로고
    • Geminin regulates multiple steps of the chromosome inheritance cycle
    • Tachibana, K.E. and Nigg, E.A. (2006) Geminin regulates multiple steps of the chromosome inheritance cycle. Cell Cycle 5, 151-154
    • (2006) Cell Cycle , vol.5 , pp. 151-154
    • Tachibana, K.E.1    Nigg, E.A.2
  • 25
    • 27844562705 scopus 로고    scopus 로고
    • Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects
    • Tachibana, K.E., Gonzalez, M.A., Guarguaglini, G., Nigg, E.A. and Laskey, R.A. (2005) Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO Rep. 6, 1052-1057
    • (2005) EMBO Rep , vol.6 , pp. 1052-1057
    • Tachibana, K.E.1    Gonzalez, M.A.2    Guarguaglini, G.3    Nigg, E.A.4    Laskey, R.A.5
  • 26
    • 0030849742 scopus 로고    scopus 로고
    • Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
    • Tanaka, T., Knapp, D. and Nasmyth, K. (1997) Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Cell 90, 649-660
    • (1997) Cell , vol.90 , pp. 649-660
    • Tanaka, T.1    Knapp, D.2    Nasmyth, K.3
  • 28
    • 0034194602 scopus 로고    scopus 로고
    • Dynamics of cytoplasmic dynein in living cells and the effect of a mutation in the dynactin complex actin-related protein Arp1
    • Xiang, X., Han, G., Winkelmann, D.A., Zuo, W. and Morris, N.R. (2000) Dynamics of cytoplasmic dynein in living cells and the effect of a mutation in the dynactin complex actin-related protein Arp1. Curr. Biol. 10, 603-606
    • (2000) Curr. Biol , vol.10 , pp. 603-606
    • Xiang, X.1    Han, G.2    Winkelmann, D.A.3    Zuo, W.4    Morris, N.R.5
  • 30
    • 0037175048 scopus 로고    scopus 로고
    • Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity
    • Yanagi, K., Mizuno, T., You, Z. and Hanaoka, F. (2002) Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity. J. Biol. Chem. 277, 40871-40880
    • (2002) J. Biol. Chem , vol.277 , pp. 40871-40880
    • Yanagi, K.1    Mizuno, T.2    You, Z.3    Hanaoka, F.4
  • 32
    • 3543041247 scopus 로고    scopus 로고
    • Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint
    • Zhu, W., Chen, Y. and Dutta, A. (2004) Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint. Mol. Cell. Biol. 24, 7140-7150
    • (2004) Mol. Cell. Biol , vol.24 , pp. 7140-7150
    • Zhu, W.1    Chen, Y.2    Dutta, A.3


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