Xenopus wntless and the retromer complex cooperate to regulate XWnt4 secretion

Molecular and Cellular Biology

Volumn 29, Issue 8, 2009, Pages 2118-2128

  Kim, Hyunjoon ^a   Cheong, Seong Moon ^a   Ryu, Jihae ^a   Jung, Hwa Jin ^b   Jho, Eek Hoon ^b   Han, Jin Kwan ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b University of Seoul   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

WNT4 PROTEIN;

ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EYE DEVELOPMENT; GENE EXPRESSION; MESODERM; MOLECULAR CLONING; NEURAL TUBE DEFECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; XENOPUS LAEVIS;

ANIMALS; EMBRYONIC INDUCTION; EYE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MESODERM; MULTIPROTEIN COMPLEXES; NEURAL TUBE; VESICULAR TRANSPORT PROTEINS; WNT PROTEINS; XENOPUS LAEVIS; XENOPUS PROTEINS;

DROSOPHILA MELANOGASTER; XENOPUS LAEVIS;

EID: 64649088009     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01503-08     Document Type: Article

References (50)

1. Baker, J. C, R. S. Beddington, and R. M. Harland. 1999. Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development. Genes Dev. 13:3149-3159.
2. Banziger, C, D. Soldini, C. Schutt, P. Zipperlen, G. Hausmann, and K. Basler. 2006. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125:509-522.
3. Bartscherer, K., N. Pelte, D. Ingelfinger, and M. Boutros. 2006. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125:523-533.
4. Belenkaya, T. Y., Y. Wu, X. Tang, B. Zhou, L. Cheng, Y. V. Sharma, D. Yan, E. M. Selva, and X. Lin. 2008. The retromer complex influences wnt secretion by recycling wntless from endosomes to the trans-Golgi network. Dev. Cell 14:120-131.
5. Bhanot, P., M. Brink, C. H. Samos, J. C. Hsieh, Y. Wang, J. P. Macke, D. Andrew, J. Nathans, and R. Nusse. 1996. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382:225-Brown.
6. Bolognesi, R., L. Farzana, T. D. Fischer, and S. J. Brown. 2008. Multiple Wnt genes are required for segmentation in the short-germ embryo of Tribolium castaneum. Curr. Biol. 18:1624-1629.
7. Bonifacino, J. S., and R. Rojas. 2006. Retrograde transport from endosomes to the trans-Golgi network. Nat. Rev. Mol. Cell Biol. 7:568-579.
8. Chen, W., D. ten Berge, J. Brown, S. Ahn, L. A. Hu, W. E. Miller, M. G. Caron, L. S. Barak, R. Nusse, and R. J. Leikowitz. 2003. Dishevelled 2 recruits beta-Arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 301:1391-1394.
9. Ching, W., H. C. Hang, and R. Nusse. 2008. Lipid-independent secretion of a Drosophila Wnt protein. J. Biol. Chem. 283:17092-17098.
10. Christian, J. L., J. A. McMahon, A, P. McMahon, and R. T. Moon. 1991. Xwnt-8, a Xenopus Wnt-1/Int-l-related gene responsive to mesoderm-in-ducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development 111:1045-1055.
11. Coolen, M., K. Sii-Felice, O. Bronchain, A. Mazabraud, F. Bourrat, S. Retaux, M. P. Felder-Schmittbuhl, S. Mazan, and J. L. Plouhinec. 2005. Phylogenomic analysis and expression patterns of large Maf genes in Xenopus tropicalis provide new insights into the functional evolution of the gene family in osteichthyans. Dev. Genes Evol. 215:327-339.
12. Coudreuse, D. Y., G. Roel, M. C. Betist, O. Destree, and H. C. Korswagen. 2006. Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312:921-924.
13. de Iongh, R. U., H. E. Abud, and G. R. Hime. 2006. WNT/Frizzled signaling in eye development and disease. Front. Biosci. 11:2442-2464.
14. Eaton, S. 2008. Retromer retrieves wntless. Dev. Cell 14:4-6.
15. Franch-Marro, X., F. Wendler, S. Guidato, J. Griffith, A. Baena-Lopez, N. Itasaki, M. M. Maurice, and J. P. Vincent. 2008. Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat. Cell Biol. 10:170-177.
16. Goodman, R. M., S. Thombre, Z. Firtina, D. Gray, D. Betts, J. Roebuck, E. P. Spana, and E. M. Selva. 2006. Sprinter: a novel transmembrane protein required for Wg secretion and signaling. Development 133:4901-4911.
17. Gordon, M. D., and R. Nusse. 2006. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J. Biol. Chem. 281: 22429-22433.
18. Harland, R. M. 1991. In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol. 36:685-695.
19. Heeg-Truesdell, E., and C. LaBonne. 2006. Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling. Dev. Biol. 298:71-86.
20. Ishibashi, S., and K. Yasuda. 2001. Distinct roles of maf genes during Xenopus lens development. Mech. Dev. 101:155-166.
21. Kim, G. H., and J. K. Han. 2007. Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements. EMBO J. 26:2513-2526.
22. Ku, M., and D. A. Melton. 1993. Xwnt-11: a maternally expressed Xenopus wnt gene. Development 119:1161-1173.
23. Lee, H. X., A. L. Ambrosio, B. Reversade, and E. M. De Robertis. 2006. Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell 124:147-159.
24. Li, Y., and G. Bu. 2005. LRP5/6 in Wnt signaling and tumorigenesis. Future Oncol. 1:673-681.
25. Locker, M., M. Agathocleous, M. A. Amato, K. Parain, W. A. Harris, and M. Perron. 2006. Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors. Genes Dev. 20:3036-3048.
26. Maurus, D., C. Heligon, A, Burger-Schwarzler, A, W. Brandli, and M. Kuhl. 2005. Noncanonical Wnt-4 signaling and EAF2 are required for eye development in Xenopus laevis. EMBO J. 24:1181-1191.
27. Mikels, A. J., and R. Nusse. 2006. Wnts as ligands: processing, secretion and reception. Oncogene 25:7461-7468.
28. Miura, G. I., J. Buglino, D. Alvarado, M. A, Lemmon, M. D. Resh, and J. E. Treisman. 2006. Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. Dev. Cell 10:167-176.
29. Moon, R. T., B. Bowerman, M. Boutros, and N. Perrimon. 2002. The promise and perils of Wnt signaling through beta-catenin. Science 296:1644-1646.
30. Moon, R. T., R. M. Campbell, J. L. Christian, L. L. McGrew, J. Shih, and S. Fraser. 1993. Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis. Development 119:97-111.
31. Nieuwkoop, P. D., and J. Faber. 1967. Normal table of Xenopus laevis (Daudin). North Holland, Amsterdam, The Netherlands.
32. Pan, C. L., P. D. Baum, M. Gu, E. M. Jorgensen, S. G. Clark, and G. Garriga. 2008. C. elegans AP-2 and retromer control Wnt signaling by regulating MIG-14/Wntless. Dev. Cell 14:132-139.
33. Panakova, D., H. Sprang, E. Marois, C. Thiele, and S. Eaton. 2005. Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature 435:58-65.
34. Perron, M., S. Kanekar, M. L. Vetter, and W. A, Harris. 1998. The genetic sequence of retinal development in the ciliary margin of the Xenopus eye. Dev. Biol. 199:185-200.
35. Port, F., M. Kuster, P. Herr, E. Furger, C. Banziger, G. Hausmann, and K. Basler. 2008. Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat. Cell Biol. 10:178-185.
36. Povelones, M., and R. Nusse. 2002. Wnt signalling sees spots. Nat. Cell Biol. 4:E249-E250.
37. Rasmussen, J. T., M. A, Deardorff, C. Tan, M. S. Rao, P. S. Klein, and M. L. Vetter. 2001. Regulation of eye development by frizzled signaling in Xenopus. Proc. Natl. Acad. Sci. USA 98:3861-3866.
38. Saulnier, D. M., H. Ghanbari, and A, W. Brandli. 2002. Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney. Dev. Biol. 248: 13-28.
39. Shibata, M, M. Itoh, H. Hikasa, S. Taira, and M. Taira. 2005. Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis. Mech. Dev. 122:1322-1339.
40. Sumanas, S., and S. C. Ekker. 2001. Xenopus frizzled-5: a frizzled family member expressed exclusively in the neural retina of the developing eye. Mech. Dev. 103:133-136.
41. Tada, M., and J. C. Smith. 2000. Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127:2227-2238.
42. Tao, Q., C. Yokota, H. Puck, M. Kofron, B. Birsoy, D. Yan, M. Asashima, C. C. Wylie, X. Lin, and J. Heasman. 2005. Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus mbryos. Cell 120:857-871.
43. Van Raay, T. J., K. B. Moore, I. Iordanova, M. Steele, M. Jamrich, W. A. Harris, and M. L. Vetter. 2005. Frizzled 5 signaling governs the neuralpotential of progenitors in the developing Xenopus retina. Neuron 46:23-36.
44. Villanueva, S., A. Glavic, P. Ruiz, and R. Mayor. 2002. Posteriorization byFGF, Wnt, and retinoic acid is required for neural crest induction. Dev. Biol. 241:289-301.
45. Wallingford, J. B., K. M. Vogeli, and R. M. Harland. 2001. Regulation ofconvergent extension in Xenopus by Wnt5a and Frizzled-8 is independent ofthe canonical Wnt pathway. Int. J. Dev. Biol. 45:225-227.
46. Wehrli, M., S. T. Dougan, K. Caldwell, L. ÓKeefe, S. Schwartz, D. Vaizel-Ohayon, E. Schejter, A. Tomlinson, and S. DiNardo. 2000. arrow encodes anLDL-receptor-related protein essential for Wingless signalling. Nature 407:527-530.
47. Westfall, T. A., R. Brimeyer, J. Twedt, J. Gladon, A. Olberding, M. Furutani-Seiki, and D. C. Slusarski. 2003. Wnt-5/pipetail functions in vertebrate axisformation as a negative regulator of Wnt/beta-catenin activity. J. Cell Biol. 162:889-898.
48. Wodarz, A., and R. Nusse. 1998. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14:59-88.
49. Wu, C. H., and R. Nusse. 2002. Ligand receptor interactions in the Wntsignaling pathway in Drosophila. J. Biol. Chem. 277:41762-41769.
50. Yang, P. T., M. J. Lorenowicz, M. Silhankova, D. Y. Coudreuse, M. C. Betist, and H. C. Korswagen. 2008. Wnt signaling requires retromer-dependentrecycling of MIG-14/Wntless in Wnt-producing cells. Dev. Cell 14:140-147.