Astilbotriterpenic acid induces growth arrest and apoptosis in HeLa cells through mitochondria-related pathways and reactive oxygen species (ROS) production

Chemistry and Biodiversity

Volumn 6, Issue 2, 2009, Pages 218-230

  Zhang, Yi Bin ^a   Ye, Yi Ping ^b   Wu, Xiao Dan ^c   Sun, Hong Xiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASTILBOTRITERPENIC ACID; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRITERPENOID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ATTENUATION; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL LINE; CELL PROLIFERATION; G0 PHASE; G1 PHASE; HELA CELLS; HUMANS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRITERPENES;

ASTILBE CHINENSIS;

EID: 64549162924     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200700427     Document Type: Article

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