메뉴 건너뛰기




Volumn 29, Issue 2, 2009, Pages 224-238

The cost-effectiveness of screening for hereditary hemochromatosis in Germany: A remodeling study

Author keywords

Cost effectiveness analysis; Genetic predisposition to disease; Genetic screening; Germany; Hereditary hemochromatosis.

Indexed keywords

ADULT; ARTICLE; CLINICAL DECISION MAKING; COST EFFECTIVENESS ANALYSIS; DNA DETERMINATION; FOLLOW UP; GENE MUTATION; GENETIC ANALYSIS; GENETIC DISORDER; GENOTYPE; GERMANY; HEALTH CARE COST; HEMOCHROMATOSIS; HUMAN; MALE; PHENOTYPE; PROGENY; REIMBURSEMENT; SCREENING TEST;

EID: 64549148979     PISSN: 0272989X     EISSN: 1552681X     Source Type: Journal    
DOI: 10.1177/0272989X08327112     Document Type: Article
Times cited : (36)

References (58)
  • 3
    • 33845487333 scopus 로고    scopus 로고
    • Current impact of gene technology on healthcare: A map of economic assessments
    • Rogowski W. Current impact of gene technology on healthcare: a map of economic assessments. Health Pol. 2007 ; 80: 340-57.
    • (2007) Health Pol , vol.80 , pp. 340-57
    • Rogowski, W.1
  • 4
    • 33746830877 scopus 로고    scopus 로고
    • Screening for hereditary hemochromatosis: A systematic review for the U.S. Preventive Services Task Force
    • Whitlock EP, Garlitz BA, Harris EL, Beil TL, Smith PR Screening for hereditary hemochromatosis: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2006 ; 145: 209-23.
    • (2006) Ann Intern Med , vol.145 , pp. 209-23
    • Whitlock, E.P.1    Garlitz, B.A.2    Harris, E.L.3    Beil, T.L.4    Smith, P.R.5
  • 5
    • 33846338525 scopus 로고    scopus 로고
    • Haemochromatosis
    • DOI 10.1016/j.mpmed.2006.11.014, PII S1357303906007080, Liver Disorder part 2 of 2
    • Adams PC, Barton JC Haemochromatosis. Lancet. 2007 ; 370: 1855-60. (Pubitemid 46126729)
    • (2007) Medicine , vol.35 , Issue.2 , pp. 89-92
    • Rosenberg, W.1
  • 6
    • 0029029626 scopus 로고
    • Screening blood donors for hereditary hemochromatosis: Decision analysis model based on a 30-year database
    • Adams PC, Gregor JC, Kertesz AE, Valberg LS Screening blood donors for hereditary hemochromatosis: decision analysis model based on a 30-year database. Gastroenterology. 1995 ; 109: 177-88.
    • (1995) Gastroenterology , vol.109 , pp. 177-88
    • Adams, P.C.1    Gregor, J.C.2    Kertesz, A.E.3    Valberg, L.S.4
  • 7
    • 0028802963 scopus 로고
    • Screening for hemochromatosis in children of homozygotes: Prevalence and cost-effectiveness
    • Adams PC, Kertesz AE, Valberg LS Screening for hemochromatosis in children of homozygotes: prevalence and cost-effectiveness. Hepatology. 1995 ; 22: 1720-7.
    • (1995) Hepatology , vol.22 , pp. 1720-7
    • Adams, P.C.1    Kertesz, A.E.2    Valberg, L.S.3
  • 8
    • 0033050583 scopus 로고    scopus 로고
    • Screening blood donors for hereditary hemochromatosis: Decision analysis model comparing genotyping to phenotyping
    • Adams PC, Valberg LS Screening blood donors for hereditary hemochromatosis: decision analysis model comparing genotyping to phenotyping. Am J Gastroenterol. 1999 ; 94: 1593-600.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1593-600
    • Adams, P.C.1    Valberg, L.S.2
  • 9
    • 0036793757 scopus 로고    scopus 로고
    • Benefit of population-based screening for phenotypic hemochromatosis in young men
    • DOI 10.1080/003655202760373443
    • Asberg A., Tretli S., Hveem K., Bjerve KS Benefit of population-based screening for phenotypic hemochromatosis in young men. Scand J Gastroenterol. 2002 ; 37: 1212-9. (Pubitemid 35178688)
    • (2002) Scandinavian Journal of Gastroenterology , vol.37 , Issue.10 , pp. 1212-1219
    • Asberg, A.1    Tretli, S.2    Hveem, K.3    Bjerve, K.S.4
  • 10
    • 0028069898 scopus 로고
    • Cost-effectiveness analysis for evaluation of screening programs: Hereditary hemochromatosis
    • Buffone GJ, Beck JR Cost-effectiveness analysis for evaluation of screening programs: hereditary hemochromatosis. Clin Chem. 1994 ; 40: 1631-6.
    • (1994) Clin Chem , vol.40 , pp. 1631-6
    • Buffone, G.J.1    Beck, J.R.2
  • 11
    • 0034651590 scopus 로고    scopus 로고
    • Screening for hereditary hemochromatosis in siblings and children of affected patients: A cost-effectiveness analysis
    • El-Serag HB, Inadomi JM, Kowdley KV Screening for hereditary hemochromatosis in siblings and children of affected patients: a cost-effectiveness analysis. Ann Intern Med. 2000 ; 132: 261-9.
    • (2000) Ann Intern Med , vol.132 , pp. 261-9
    • El-Serag, H.B.1    Inadomi, J.M.2    Kowdley, K.V.3
  • 12
    • 33845545966 scopus 로고    scopus 로고
    • Hereditary hemochromatosis screening: Effect of mutation penetrance and prevalence on cost-effectiveness of testing algorithms
    • Gagné G., Reinharz D., Laflamme N., Adams P., Rousseau F. Hereditary hemochromatosis screening: effect of mutation penetrance and prevalence on cost-effectiveness of testing algorithms. Clin Genet. 2007 ; 71: 46-58.
    • (2007) Clin Genet , vol.71 , pp. 46-58
    • Gagné, G.1    Reinharz, D.2    Laflamme, N.3    Adams, P.4    Rousseau, F.5
  • 13
    • 0033761666 scopus 로고    scopus 로고
    • Cost-effectiveness of population-based genetic hemochromatosis screening
    • Schöffski O., Schmidtke J., Stuhrmann M. Cost-effectiveness of population-based genetic hemochromatosis screening. Community Genetics. 2000 ; 3: 2-11.
    • (2000) Community Genetics , vol.3 , pp. 2-11
    • Schöffski, O.1    Schmidtke, J.2    Stuhrmann, M.3
  • 15
    • 33749155617 scopus 로고    scopus 로고
    • Genetic screening by DNA technology: A systematic review of health economic evidence
    • DOI 10.1017/S0266462306051221, PII S0266462306051221
    • Rogowski W. Genetic screening by DNA technology: a systematic review of health economic evidence. Int J Technol Assess Health Care. 2006 ; 22: 327-37. (Pubitemid 44469439)
    • (2006) International Journal of Technology Assessment in Health Care , vol.22 , Issue.3 , pp. 327-337
    • Rogowski, W.1
  • 17
    • 25444500981 scopus 로고    scopus 로고
    • Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: Systematic review for the American College of Physicians
    • Schmitt B., Golub RM, Green R. Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: systematic review for the American College of Physicians. Ann Intern Med. 2005 ; 143: 522-36. (Pubitemid 41377201)
    • (2005) Annals of Internal Medicine , vol.143 , Issue.7
    • Schmitt, B.1    Golub, R.M.2    Green, R.3
  • 18
    • 33744921460 scopus 로고    scopus 로고
    • Liver diseases in the hemochromatosis and iron overload screening study
    • Adams PC, Passmore L., Chakrabarti S., et al. Liver diseases in the hemochromatosis and iron overload screening study. Clin Gastroenterol Hepatol. 2006 ; 4: 918-23 ; quiz 807.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 918-23
    • Adams, P.C.1    Passmore, L.2    Chakrabarti, S.3
  • 19
    • 38349079861 scopus 로고    scopus 로고
    • Iron-overload- related disease in HFE hereditary hemochromatosis
    • Allen KJ, Gurrin LC, Constantine CC, et al. Iron-overload- related disease in HFE hereditary hemochromatosis. N Engl J Med. 2008 ; 358: 221-30.
    • (2008) N Engl J Med , vol.358 , pp. 221-30
    • Allen, K.J.1    Gurrin, L.C.2    Constantine, C.C.3
  • 20
    • 33645810425 scopus 로고    scopus 로고
    • Good practice guidelines for decision-analytic modelling in health technology assessment: A review and consolidation of quality assessment
    • Philips Z., Bojke L., Sculpher M., Claxton K., Golder S. Good practice guidelines for decision-analytic modelling in health technology assessment: a review and consolidation of quality assessment. Pharmacoeconomics. 2006 ; 24: 355-71.
    • (2006) Pharmacoeconomics , vol.24 , pp. 355-71
    • Philips, Z.1    Bojke, L.2    Sculpher, M.3    Claxton, K.4    Golder, S.5
  • 21
    • 20244372858 scopus 로고    scopus 로고
    • Hemochromatosis and iron-overload screening in a racially diverse population
    • Adams PC, Reboussin DM, Barton JC, et al. Hemochromatosis and iron-overload screening in a racially diverse population. N Engl J Med. 2005 ; 352: 1769-78.
    • (2005) N Engl J Med , vol.352 , pp. 1769-78
    • Adams, P.C.1    Reboussin, D.M.2    Barton, J.C.3
  • 22
    • 0034928709 scopus 로고    scopus 로고
    • Estimating the efficacy and efficiency of cascade genetic screening
    • DOI 10.1086/321973
    • Krawczak M., Cooper DN, Schmidtke J. Estimating the efficacy and efficiency of cascade genetic screening. Am J Hum Genet. 2001 ; 69: 361-70. (Pubitemid 32695208)
    • (2001) American Journal of Human Genetics , vol.69 , Issue.2 , pp. 361-370
    • Krawczak, M.1    Cooper, D.N.2    Schmidtke, J.3
  • 23
    • 27144512248 scopus 로고    scopus 로고
    • Genotype-based screening for hereditary hemochromatosis: II. Attitudes toward genetic testing and psychosocial impact - A report from a german pilot study
    • DOI 10.1089/gte.2005.9.242
    • Stuhrmann M., Hoy L., Nippert I., Schmidtke J. Genotype-based screening for hereditary hemochromatosis: II. Attitudes toward genetic testing and psychosocial impact-a report from a German pilot study. Genet Test. 2005 ; 9: 242-54. (Pubitemid 41507757)
    • (2005) Genetic Testing , vol.9 , Issue.3 , pp. 242-254
    • Stuhrmann, M.1    Hoy, L.2    Nippert, I.3    Schmidtke, J.4
  • 24
    • 33750583986 scopus 로고    scopus 로고
    • Leitlinie zur molekulargenetischen diagnostik der hereditaren hamochromatose
    • Gabriel H., Stuhrmann M. Leitlinie zur molekulargenetischen Diagnostik der hereditären Hämochromatose. Medizinische Genetik. 2006 ; 18: 273-8. (Pubitemid 44681270)
    • (2006) Medizinische Genetik , vol.18 , Issue.3 , pp. 273-277
    • Gabriel, H.1    Stuhrmann-Spangenberg, M.2
  • 25
    • 27144512248 scopus 로고    scopus 로고
    • Genotype-based screening for hereditary hemochromatosis: II. Attitudes toward genetic testing and psychosocial impact - A report from a german pilot study
    • DOI 10.1089/gte.2005.9.242
    • Stuhrmann M., Strassburg C., Schmidtke J. Genotype-based screening for hereditary haemochromatosis: I. Technical performance, costs and clinical relevance of a German pilot study. Eur J Hum Genet. 2005 ; 13: 69-78. (Pubitemid 41507757)
    • (2005) Genetic Testing , vol.9 , Issue.3 , pp. 242-254
    • Stuhrmann, M.1    Hoy, L.2    Nippert, I.3    Schmidtke, J.4
  • 28
    • 1442282237 scopus 로고    scopus 로고
    • Evolution of Untreated Hereditary Hemochromatosis in the Busselton Population: A 17-Year Study
    • Olynyk JK, Hagan SE, Cullen DJ, Beilby J., Whittall DE Evolution of untreated hereditary hemochromatosis in the Busselton population: a 17-year study. Mayo Clin Proc. 2004 ; 79: 309-13. (Pubitemid 38269232)
    • (2004) Mayo Clinic Proceedings , vol.79 , Issue.3 , pp. 309-313
    • Olynyk, J.K.1    Hagan, S.E.2    Cullen, D.J.3    Beilby, J.4    Whittall, D.E.5
  • 31
    • 0031793132 scopus 로고    scopus 로고
    • The significance of haemochromatosis gene mutations in the general population: Implications for screening
    • Burt MJ, George PM, Upton JD, et al. The significance of haemochromatosis gene mutations in the general population: implications for screening. Gut. 1998 ; 43: 830-6.
    • (1998) Gut , vol.43 , pp. 830-6
    • Burt, M.J.1    George, P.M.2    Upton, J.D.3
  • 32
    • 22544455045 scopus 로고    scopus 로고
    • Use of community genetic screening to prevent HFE-associated hereditary haemochromatosis
    • Delatycki MB, Allen KJ, Nisselle AE, et al. Use of community genetic screening to prevent HFE-associated hereditary haemochromatosis. Lancet. 2005 ; 366: 314-6.
    • (2005) Lancet , vol.366 , pp. 314-6
    • Delatycki, M.B.1    Allen, K.J.2    Nisselle, A.E.3
  • 34
    • 35449004475 scopus 로고    scopus 로고
    • Biological variability of transferrin saturation and unsaturated iron-binding capacity
    • Adams PC, Reboussin DM, Press RD, et al. Biological variability of transferrin saturation and unsaturated iron-binding capacity. Am J Med. 2007 ; 120: 999.e1-7.
    • (2007) Am J Med , vol.120
    • Adams, P.C.1    Reboussin, D.M.2    Press, R.D.3
  • 35
    • 0141794515 scopus 로고    scopus 로고
    • Patient compliance with phlebotomy therapy for iron overload associated with hemochromatosis
    • Hicken BL, Tucker DC, Barton JC Patient compliance with phlebotomy therapy for iron overload associated with hemochromatosis. Am J Gastroenterol. 2003 ; 98: 2072-7.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2072-7
    • Hicken, B.L.1    Tucker, D.C.2    Barton, J.C.3
  • 36
    • 0029919387 scopus 로고    scopus 로고
    • Recommendations for reporting cost-effectiveness analyses: Panel on Cost-Effectiveness in Health and Medicine
    • Siegel JE, Weinstein MC, Russell LB, Gold MR Recommendations for reporting cost-effectiveness analyses: Panel on Cost-Effectiveness in Health and Medicine. JAMA. 1996 ; 276: 1339-41.
    • (1996) JAMA , vol.276 , pp. 1339-41
    • Siegel, J.E.1    Weinstein, M.C.2    Russell, L.B.3    Gold, M.R.4
  • 37
    • 27744475482 scopus 로고    scopus 로고
    • Empirische bewertungssatze in der gesundheitsokonomischen evaluation - Ein vorschlag der AG methoden der gesundheitsokonomischen evaluation (AG MEG)
    • DOI 10.1055/s-2005-858698
    • Krauth C., Hessel F., Klingelhofer HE, Schweikert B., Hansmeier T., Wasem J. Empirische Bewertungssätze in der gesundheitsöko nomischen Evaluation: Ein Vorschlag der AG Gesundheitsökonomische Methoden (AG MEG). Rehabilitation (Stuttg). 2005 ; 44: 297-306. (Pubitemid 41604934)
    • (2005) Gesundheitswesen , vol.67 , Issue.10 , pp. 736-746
    • Krauth, C.1    Hessel, F.2    Hansmeier, T.3    Wasem, J.4    Seitz, R.5    Schweikert, B.6
  • 38
    • 36049022163 scopus 로고    scopus 로고
    • German recommendations on health economic evaluation: Third and updated version of the Hanover Consensus
    • von der Schulenburg JMG, Greiner W., et al. German recommendations on health economic evaluation: third and updated version of the Hanover Consensus. Gesundh Okon Qual Manage. 2007 ; 12: 285-90.
    • (2007) Gesundh Okon Qual Manage , vol.12 , pp. 285-90
    • Von Der Schulenburg, J.M.G.1    Greiner, W.2
  • 40
    • 4544286541 scopus 로고    scopus 로고
    • Institute For Health And Clinical Excellence N
    • National Institute for Health and Clinical Excellence. Guide to the methods of technology appraisal. 2004 [cited 17 May 2005]. Available from: http://www.nice.org.uk/pdf/TAP-Methods.pdf
    • (2004) Guide to the Methods of Technology Appraisal
  • 41
    • 0037065322 scopus 로고    scopus 로고
    • Helping patients follow prescribed treatment: Clinical applications
    • Haynes RB, McDonald HP, Garg AX Helping patients follow prescribed treatment: clinical applications. JAMA. 2002 ; 288: 2880-3.
    • (2002) JAMA , vol.288 , pp. 2880-3
    • Haynes, R.B.1    McDonald, H.P.2    Garg, A.X.3
  • 42
    • 0037065355 scopus 로고    scopus 로고
    • Interventions to enhance patient adherence to medication prescriptions: Scientific review
    • DOI 10.1001/jama.288.22.2868
    • McDonald HP, Garg AX, Haynes RB Interventions to enhance patient adherence to medication prescriptions: scientific review. JAMA. 2002 ; 288: 2868-79. (Pubitemid 35425073)
    • (2002) Journal of the American Medical Association , vol.288 , Issue.22 , pp. 2868-2879
    • McDonald, H.P.1    Garg, A.X.2    Haynes, R.B.3
  • 44
  • 45
    • 0035678345 scopus 로고    scopus 로고
    • Clinically overt hereditary hemochromatosis in Denmark 1948-1985: Epidemiology, factors of significance for long-term survival, and causes of death in 179 patients
    • DOI 10.1007/s002770100371
    • Milman N., Pedersen P., á Steig T., Byg KE, Graudal N., Fenger K. Clinically overt hereditary hemochromatosis in Denmark 1948-1985: epidemiology, factors of significance for long-term survival, and causes of death in 179 patients. Ann Hematol. 2001 ; 80: 737-44. (Pubitemid 34044096)
    • (2001) Annals of Hematology , vol.80 , Issue.12 , pp. 737-744
    • Milman, N.1    Pedersen, P.2    Steig, T.3    Byg, K.-E.4    Graudal, N.5    Fenger, K.6
  • 46
    • 33747878216 scopus 로고    scopus 로고
    • What is the clinical utility of genetic testing
    • Grosse SD, Khoury MJ What is the clinical utility of genetic testing ? Genet Med. 2006 ; 8: 448-50.
    • (2006) Genet Med , vol.8 , pp. 448-50
    • Grosse, S.D.1    Khoury, M.J.2
  • 47
    • 0037413486 scopus 로고    scopus 로고
    • Population screening in the age of genomic medicine
    • Khoury MJ, McCabe LL, McCabe ER Population screening in the age of genomic medicine. N Engl J Med. 2003 ; 348: 50-8.
    • (2003) N Engl J Med , vol.348 , pp. 50-8
    • Khoury, M.J.1    McCabe, L.L.2    McCabe, E.R.3
  • 48
    • 34147103934 scopus 로고    scopus 로고
    • Psychosocial impact of genetic testing for hemochromatosis in the HEIRS Study: A comparison of participants recruited in Canada and in the United States
    • DOI 10.1089/gte.2006.0512
    • Power TE, Adams PC, Barton JC, et al. Psychosocial impact of genetic testing for hemochromatosis in the HEIRS Study: a comparison of participants recruited in Canada and in the United States. Genet Test. 2007 ; 11: 55-64. (Pubitemid 46557358)
    • (2007) Genetic Testing , vol.11 , Issue.1 , pp. 55-64
    • Power, T.E.1    Adams, P.C.2    Barton, J.C.3    Acton, R.T.4    Howe Iii, E.5    Palla, S.6    Walker, A.P.7    Anderson, R.8    Harrison, B.9
  • 51
    • 0344035572 scopus 로고    scopus 로고
    • Estimated analytic validity of HFE C282Y mutation testing in population screening: The potential value of confirmatory testing
    • DOI 10.1097/01.GIM.0000096500.66084.85
    • Palomaki GE, Haddow JE, Bradley LA, Richards CS, Stenzel TT, Grody WW Estimated analytic validity of HFE C282Y mutation testing in population screening: the potential value of confirmatory testing. Genet Med. 2003 ; 5: 440-3. (Pubitemid 37483413)
    • (2003) Genetics in Medicine , vol.5 , Issue.6 , pp. 440-443
    • Palomaki, G.E.1    Haddow, J.E.2    Bradley, L.A.3    Richards, C.S.4    Stenzel, T.T.5    Grody, W.W.6
  • 52
    • 0017142698 scopus 로고
    • Long term results of venesection therapy in idiopathic haemochromatosis
    • Bomford A., Williams R. Long term results of venesection therapy in idiopathic haemochromatosis. Q J Med. 1976 ; 45: 611-23.
    • (1976) Q J Med , vol.45 , pp. 611-23
    • Bomford, A.1    Williams, R.2
  • 53
    • 2442715056 scopus 로고    scopus 로고
    • Implementation of HaemScreen, a workplace-based genetic screening program for hemochromatosis
    • Nisselle AE, Delatycki MB, Collins V., et al. Implementation of HaemScreen, a workplace-based genetic screening program for hemochromatosis. Clin Genet. 2004 ; 65: 358-67.
    • (2004) Clin Genet , vol.65 , pp. 358-67
    • Nisselle, A.E.1    Delatycki, M.B.2    Collins, V.3
  • 57
    • 18244409599 scopus 로고    scopus 로고
    • Health care reform in Germany: Patchwork change within established governance structures
    • DOI 10.1215/03616878-30-1-2-121
    • Altenstetter C., Busse R. Health care reform in Germany: patchwork change within established governance structures. J Health Polit Policy Law. 2005 ; 30: 121-42. (Pubitemid 40627009)
    • (2005) Journal of Health Politics, Policy and Law , vol.30 , Issue.1-2 , pp. 121-142
    • Altenstetter, C.1    Busse, R.2
  • 58
    • 0344687289 scopus 로고    scopus 로고
    • Screening for hereditary haemochromatosis within families and beyond
    • DOI 10.1016/S0140-6736(03)14963-X
    • McCune CA, Ravine D., Worwood M., Jackson HA, Evans HM, Hutton D. Screening for hereditary haemochromatosis within families and beyond. Lancet. 2003 ; 362: 1897-8. (Pubitemid 37518508)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1897-1898
    • McCune, C.A.1    Ravine, D.2    Worwood, M.3    Jackson, H.A.4    Evans, H.M.5    Hutton, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.