메뉴 건너뛰기




Volumn 15, Issue 3-4, 2009, Pages 95-100

High serum Aβ and vascular risk factors in first-degree relatives of alzheimer's disease patients

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; APOLIPOPROTEIN E; CALCIUM CHANNEL BLOCKING AGENT; CELECOXIB; CREATININE; DIHYDROPYRIDINE DERIVATIVE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

EID: 64549109277     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2008.00118     Document Type: Article
Times cited : (14)

References (40)
  • 1
    • 0033864011 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease: The role of beta-amyloid and the presenilins
    • Tandon A, Rogaeva E, Mullan M, St George-Hyslop PH. (2000) Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Curr. Opin. Neurol. 13:377-84.
    • (2000) Curr. Opin. Neurol , vol.13 , pp. 377-384
    • Tandon, A.1    Rogaeva, E.2    Mullan, M.3    St George-Hyslop, P.H.4
  • 2
    • 0242412140 scopus 로고    scopus 로고
    • Plasma Aβ40 and Aβ42 and Alzheimer's disease: Relation to age, mortality, and risk
    • Mayeux R, et al. (2003) Plasma Aβ40 and Aβ42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology. 61:1185-9.
    • (2003) Neurology , vol.61 , pp. 1185-1189
    • Mayeux, R.1
  • 3
    • 34247266089 scopus 로고    scopus 로고
    • Release of beta-amyloid from high-density platelets: Implications for Alzheimer's disease pathology
    • Casoli T, et al. (2007) Release of beta-amyloid from high-density platelets: implications for Alzheimer's disease pathology. Ann. N. Y. Acad. Sci. 1096:170-8.
    • (2007) Ann. N. Y. Acad. Sci , vol.1096 , pp. 170-178
    • Casoli, T.1
  • 5
    • 36048982129 scopus 로고    scopus 로고
    • Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: Prediction by plasma amyloid beta 42, medial temporal lobe atrophy and ho-mocysteine
    • Blasko I, et al. (2008) Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and ho-mocysteine. Neurobiol. Aging. 29:1-11.
    • (2008) Neurobiol. Aging , vol.29 , pp. 1-11
    • Blasko, I.1
  • 6
    • 35748972941 scopus 로고    scopus 로고
    • The influence of diagnosis, intra- and inter-person variability on serum and plasma Aβ levels
    • Abdullah L, et al. (2007) The influence of diagnosis, intra- and inter-person variability on serum and plasma Aβ levels. Neurosci. Lett. 428:53-8.
    • (2007) Neurosci. Lett , vol.428 , pp. 53-58
    • Abdullah, L.1
  • 7
    • 84868920786 scopus 로고    scopus 로고
    • Luis CA, et al. (2008) Serum β-amyloid levels correlate with cognitive impairment. Neuropsychol Dev. Cogn. B. Aging Neuropsychol. Cogn. 15:1-16.
    • Luis CA, et al. (2008) Serum β-amyloid levels correlate with cognitive impairment. Neuropsychol Dev. Cogn. B. Aging Neuropsychol. Cogn. 15:1-16.
  • 8
    • 0034703979 scopus 로고    scopus 로고
    • Linkage of plasma Aβp42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
    • Ertekin-Taner N, et al. (2000) Linkage of plasma Aβp42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science. 290:2303-4.
    • (2000) Science , vol.290 , pp. 2303-2304
    • Ertekin-Taner, N.1
  • 9
    • 39749090577 scopus 로고    scopus 로고
    • Plasma amyloid β protein is elevated in late-onset Alzheimer disease families
    • Ertekin-Taner N, et al. (2008) Plasma amyloid β protein is elevated in late-onset Alzheimer disease families. Neurology 70:596-606.
    • (2008) Neurology , vol.70 , pp. 596-606
    • Ertekin-Taner, N.1
  • 10
    • 0032587237 scopus 로고    scopus 로고
    • Evidence that Aβ42 plasma levels in presenilin-1 mutation carriers do not allow for prediction of their clinical phe-notype
    • De Jonghe C, et al. (1999) Evidence that Aβ42 plasma levels in presenilin-1 mutation carriers do not allow for prediction of their clinical phe-notype. Neurobiol. Dis. 6:280-7.
    • (1999) Neurobiol. Dis , vol.6 , pp. 280-287
    • De Jonghe, C.1
  • 11
    • 16044373524 scopus 로고    scopus 로고
    • Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
    • Scheuner D, et al. (1996). Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2:864-70.
    • (1996) Nat. Med , vol.2 , pp. 864-870
    • Scheuner, D.1
  • 12
    • 3142621163 scopus 로고    scopus 로고
    • Familial clustering and genetic risk for dementia in a genetically isolated Dutch population
    • Sleegers K, et al. (2004). Familial clustering and genetic risk for dementia in a genetically isolated Dutch population. Brain. 127(Pt 7):1641-9.
    • (2004) Brain , vol.127 , Issue.PART 7 , pp. 1641-1649
    • Sleegers, K.1
  • 13
    • 0028340614 scopus 로고    scopus 로고
    • Houlden H, et al. (1994). Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipopro-tein E locus. Neurosci. Lett. 174:222-4.
    • Houlden H, et al. (1994). Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipopro-tein E locus. Neurosci. Lett. 174:222-4.
  • 14
    • 0030614816 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons
    • Evans DA, et al. (1997). Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons. JAMA. 277:822-4.
    • (1997) JAMA , vol.277 , pp. 822-824
    • Evans, D.A.1
  • 16
    • 0030003819 scopus 로고    scopus 로고
    • 15-year longitudinal study of blood pressure and dementia
    • Skoog I, et al. (1996). 15-year longitudinal study of blood pressure and dementia. Lancet. 347:1141-5.
    • (1996) Lancet , vol.347 , pp. 1141-1145
    • Skoog, I.1
  • 17
    • 0034594441 scopus 로고    scopus 로고
    • Midlife blood pressure and dementia: The Honolulu-Asia aging study
    • Launer LJ, et al. (2000). Midlife blood pressure and dementia: the Honolulu-Asia aging study. Neurobiol. Aging 21:49-55.
    • (2000) Neurobiol. Aging , vol.21 , pp. 49-55
    • Launer, L.J.1
  • 18
    • 0035897938 scopus 로고    scopus 로고
    • Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
    • Kivipelto M, et al. (2001). Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. BMJ 322:1447-51.
    • (2001) BMJ , vol.322 , pp. 1447-1451
    • Kivipelto, M.1
  • 19
    • 0031976318 scopus 로고    scopus 로고
    • Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease
    • Notkola IL, et al. (1998). Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease. Neuroepidemiology 17:14-20.
    • (1998) Neuroepidemiology , vol.17 , pp. 14-20
    • Notkola, I.L.1
  • 20
    • 57749116386 scopus 로고    scopus 로고
    • β-amyloid deposition in brain is enhanced in mouse models of arterial hypertension
    • Gentile MT, et al. (2009) β-amyloid deposition in brain is enhanced in mouse models of arterial hypertension. Neurobiol. Aging 30:222-8.
    • (2009) Neurobiol. Aging , vol.30 , pp. 222-228
    • Gentile, M.T.1
  • 21
    • 7644225312 scopus 로고    scopus 로고
    • RAGE (yin) versus LRP (yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier
    • Deane R, Wu Z, Zlokovic BV. (2004) RAGE (yin) versus LRP (yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier. Stroke 35(11 Suppl 1):2628-31.
    • (2004) Stroke , vol.35 , Issue.11 SUPPL. 1 , pp. 2628-2631
    • Deane, R.1    Wu, Z.2    Zlokovic, B.V.3
  • 22
    • 0025869153 scopus 로고
    • Analysis of apolipoprotein E genotypes by the Amplification Refractory Mutation System
    • Wenham PR, Newton CR, Price WH. (1991) Analysis of apolipoprotein E genotypes by the Amplification Refractory Mutation System. Clin. Chem. 37:241-4.
    • (1991) Clin. Chem , vol.37 , pp. 241-244
    • Wenham, P.R.1    Newton, C.R.2    Price, W.H.3
  • 23
    • 34548635537 scopus 로고    scopus 로고
    • Cognitive domain decline in healthy apolipoprotein E epsilon4 homozy-gotes before the diagnosis of mild cognitive impairment
    • Caselli RJ, et al. (2007) Cognitive domain decline in healthy apolipoprotein E epsilon4 homozy-gotes before the diagnosis of mild cognitive impairment. Arch. Neurol. 64:1306-11.
    • (2007) Arch. Neurol , vol.64 , pp. 1306-1311
    • Caselli, R.J.1
  • 24
    • 43249124446 scopus 로고    scopus 로고
    • APOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer disease
    • Cosentino S, et al. (2008) APOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer disease. Neurology. 70(19 Pt 2):1842-9.
    • (2008) Neurology , vol.70 , Issue.19 PART 2 , pp. 1842-1849
    • Cosentino, S.1
  • 25
    • 33745741303 scopus 로고    scopus 로고
    • Epidemiological and clinical trials evidence about a preventive role for statins in Alzheimer's disease
    • Rockwood K. (2006) Epidemiological and clinical trials evidence about a preventive role for statins in Alzheimer's disease. Acta. Neurol. Scand. Suppl. 185:71-7.
    • (2006) Acta. Neurol. Scand. Suppl , vol.185 , pp. 71-77
    • Rockwood, K.1
  • 26
    • 65249130278 scopus 로고    scopus 로고
    • Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
    • Oct 17 [Epub ahead of print
    • Haag MD, Hofman A, Koudstaal PJ, Stricker BH, Breteler MM. (2008) Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study. J. Neurol. Neurosurg. Psychiatry. 2008, Oct 17 [Epub ahead of print].
    • (2008) J. Neurol. Neurosurg. Psychiatry. 2008
    • Haag, M.D.1    Hofman, A.2    Koudstaal, P.J.3    Stricker, B.H.4    Breteler, M.M.5
  • 27
    • 48749096049 scopus 로고    scopus 로고
    • Reduced risk of incident AD with elective statin use in a clinical trial cohort
    • Sparks DL, et al. (2008) Reduced risk of incident AD with elective statin use in a clinical trial cohort. Curr. Alzheimer Res. 5:416-21.
    • (2008) Curr. Alzheimer Res , vol.5 , pp. 416-421
    • Sparks, D.L.1
  • 28
    • 34548299453 scopus 로고    scopus 로고
    • Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease
    • Wolozin B, et al. (2007) Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease. BMC Med. 5:20.
    • (2007) BMC Med , vol.5 , pp. 20
    • Wolozin, B.1
  • 29
    • 34249825804 scopus 로고    scopus 로고
    • Effect of HMG-CoA reductase inhibitors on beta-amyloid pep-tide levels: Implications for Alzheimer's disease
    • Hoglund K, Blennow K. (2007) Effect of HMG-CoA reductase inhibitors on beta-amyloid pep-tide levels: implications for Alzheimer's disease. CNS Drugs 21:449-62.
    • (2007) CNS Drugs , vol.21 , pp. 449-462
    • Hoglund, K.1    Blennow, K.2
  • 30
    • 47649124352 scopus 로고    scopus 로고
    • Effects of medications on plasma amyloid β (Aβ) 42: Longitudinal data from the VITA cohort
    • Blasko I, et al. (2008) Effects of medications on plasma amyloid β (Aβ) 42: longitudinal data from the VITA cohort. J. Psychiatr. Res. 42:946-55.
    • (2008) J. Psychiatr. Res , vol.42 , pp. 946-955
    • Blasko, I.1
  • 31
    • 0033976870 scopus 로고    scopus 로고
    • Transthyretin in high density lipoproteins: Association with apolipoprotein A-I
    • Sousa M, Berglund ML, Saraiva MJ. (2000) Transthyretin in high density lipoproteins: association with apolipoprotein A-I. J. Lipid Res. 41:58-65.
    • (2000) J. Lipid Res , vol.41 , pp. 58-65
    • Sousa, M.1    Berglund, M.L.2    Saraiva, M.J.3
  • 32
    • 0028921915 scopus 로고
    • Characterization of apolipoprotein J-Alzheimer's Aβ interaction
    • Matsubara E, Frangione B, Ghiso J. (1995) Characterization of apolipoprotein J-Alzheimer's Aβ interaction. J. Biol. Chem. 270:7563-7.
    • (1995) J. Biol. Chem , vol.270 , pp. 7563-7567
    • Matsubara, E.1    Frangione, B.2    Ghiso, J.3
  • 33
    • 0028609448 scopus 로고
    • The soluble form of Alzheimer's amyloid β protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma
    • Koudinov A, Matsubara E, Frangione B, and Ghiso J. (1994) The soluble form of Alzheimer's amyloid β protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem. Biophys. Res. Commun. 205:1164-71.
    • (1994) Biochem. Biophys. Res. Commun , vol.205 , pp. 1164-1171
    • Koudinov, A.1    Matsubara, E.2    Frangione, B.3    Ghiso, J.4
  • 34
    • 33645502137 scopus 로고    scopus 로고
    • High density lipoproeins bind Aβ and apolipoprotein C-II amyloid fibrils
    • Wilson LM, et al. (2006). High density lipoproeins bind Aβ and apolipoprotein C-II amyloid fibrils. J. Lipid Res. 47:755-60.
    • (2006) J. Lipid Res , vol.47 , pp. 755-760
    • Wilson, L.M.1
  • 35
    • 33644592540 scopus 로고    scopus 로고
    • Plasma Aβ42 correlates positively with increased body fat in healthy individuals
    • Balakrishnan K, et al. (2005). Plasma Aβ42 correlates positively with increased body fat in healthy individuals. J. Alzheimers Dis. 8:269-82.
    • (2005) J. Alzheimers Dis , vol.8 , pp. 269-282
    • Balakrishnan, K.1
  • 37
    • 0035829592 scopus 로고    scopus 로고
    • A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
    • Weggen S, et al. (2001). A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity. Nature 414:212-6.
    • (2001) Nature , vol.414 , pp. 212-216
    • Weggen, S.1
  • 38
    • 46049108790 scopus 로고    scopus 로고
    • No advantage of Aβ 42- lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies
    • Szekely CA, et al. (2008) No advantage of Aβ 42- lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. Neurology 70:2291-8.
    • (2008) Neurology , vol.70 , pp. 2291-2298
    • Szekely, C.A.1
  • 39
    • 65249098696 scopus 로고    scopus 로고
    • Safety and efficacy of tarenflurbil in subjects with mild Alzheimer's disease: Results from an 18-month multi-center phase 3 trial
    • Green RC, Schneider LS, Hendrix SB, Zavitz KH, Swabb E. (2008) Safety and efficacy of tarenflurbil in subjects with mild Alzheimer's disease: results from an 18-month multi-center phase 3 trial. Alzheimers Dement. 4(4 Suppl):T165.
    • (2008) Alzheimers Dement , vol.4 , Issue.4 SUPPL.
    • Green, R.C.1    Schneider, L.S.2    Hendrix, S.B.3    Zavitz, K.H.4    Swabb, E.5
  • 40
    • 61849132050 scopus 로고    scopus 로고
    • Onset of Alzheimer's dementia occurs commonly without prior cognitive impairment: Results from the Alzheimer's disease anti-inflammatory prevention trial (ADAPT)
    • Breitner JCS (2008). Onset of Alzheimer's dementia occurs commonly without prior cognitive impairment: results from the Alzheimer's disease anti-inflammatory prevention trial (ADAPT). Alzheimers Dement. 4(4 Suppl):T130-1.
    • (2008) Alzheimers Dement , vol.4 , Issue.4 SUPPL.
    • Breitner, J.C.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.