-
1
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein B., Lane D., and Levine A.J. Surfing the p53 network. Nature 408 6810 (2000) 307-310
-
(2000)
Nature
, vol.408
, Issue.6810
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
2
-
-
0034818446
-
Post-translational modifications and activation of p53 by genotoxic stresses
-
Appella E., and Anderson C.W. Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 268 10 (2001) 2764-2772
-
(2001)
Eur J Biochem
, vol.268
, Issue.10
, pp. 2764-2772
-
-
Appella, E.1
Anderson, C.W.2
-
3
-
-
0038075338
-
Decision making by p53: life, death and cancer
-
Oren M. Decision making by p53: life, death and cancer. Cell Death Differ 10 4 (2003) 431-442
-
(2003)
Cell Death Differ
, vol.10
, Issue.4
, pp. 431-442
-
-
Oren, M.1
-
4
-
-
50149097809
-
A complex barcode underlies the heterogeneous response of p53 to stress
-
Murray-Zmijewski F., Slee E.A., and Lu X. A complex barcode underlies the heterogeneous response of p53 to stress. Nat Rev Mol Cell Biol 9 9 (2008) 702-712
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.9
, pp. 702-712
-
-
Murray-Zmijewski, F.1
Slee, E.A.2
Lu, X.3
-
5
-
-
0033028021
-
The dual role model for p53 in maintaining genomic integrity
-
Janus F., Albrechtsen N., Dornreiter I., Wiesmuller L., Grosse F., and Deppert W. The dual role model for p53 in maintaining genomic integrity. Cell Mol Life Sci 55 1 (1999) 12-27
-
(1999)
Cell Mol Life Sci
, vol.55
, Issue.1
, pp. 12-27
-
-
Janus, F.1
Albrechtsen, N.2
Dornreiter, I.3
Wiesmuller, L.4
Grosse, F.5
Deppert, W.6
-
6
-
-
11244344381
-
p53: traffic cop at the crossroads of DNA repair and recombination
-
Sengupta S., and Harris C.C. p53: traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol 6 1 (2005) 44-55
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.1
, pp. 44-55
-
-
Sengupta, S.1
Harris, C.C.2
-
7
-
-
0027522365
-
The p53 protein is an unusually shaped tetramer that binds directly to DNA
-
Friedman P.N., Chen X., Bargonetti J., and Prives C. The p53 protein is an unusually shaped tetramer that binds directly to DNA. Proc Natl Acad Sci U S A 90 8 (1993) 3319-3323
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.8
, pp. 3319-3323
-
-
Friedman, P.N.1
Chen, X.2
Bargonetti, J.3
Prives, C.4
-
8
-
-
0027990725
-
p53 domains: structure, oligomerization, and transformation
-
Wang P., Reed M., Wang Y., Mayr G., Stenger J.E., Anderson M.E., Schwedes J.F., and Tegtmeyer P. p53 domains: structure, oligomerization, and transformation. Mol Cell Biol 14 8 (1994) 5182-5191
-
(1994)
Mol Cell Biol
, vol.14
, Issue.8
, pp. 5182-5191
-
-
Wang, P.1
Reed, M.2
Wang, Y.3
Mayr, G.4
Stenger, J.E.5
Anderson, M.E.6
Schwedes, J.F.7
Tegtmeyer, P.8
-
9
-
-
0025731379
-
Co-translation of mutant p53 with wild type drives the wild-type p53 into the mutant conformation
-
Milner J., and Medcalf E.A. Co-translation of mutant p53 with wild type drives the wild-type p53 into the mutant conformation. Cell 65 (1991) 765-774
-
(1991)
Cell
, vol.65
, pp. 765-774
-
-
Milner, J.1
Medcalf, E.A.2
-
10
-
-
0028519273
-
Allosteric activation of latent p53 tetramers
-
Hupp T.R., and Lane D.P. Allosteric activation of latent p53 tetramers. Curr Biol 4 10 (1994) 865-875
-
(1994)
Curr Biol
, vol.4
, Issue.10
, pp. 865-875
-
-
Hupp, T.R.1
Lane, D.P.2
-
11
-
-
33144475212
-
Core domain interactions in full-length p53 in solution
-
NMR studies of full length human p53 with four stabilising mutations in the core domain. This paper describes interactions between core domains for free p53 and in complex with DNA.
-
Veprintsev D.B., Freund S.M., Andreeva A., Rutledge S.E., Tidow H., Cañadillas J.M., Blair C.M., and Fersht A.R. Core domain interactions in full-length p53 in solution. Proc Natl Acad Sci U S A 103 7 (2006) 2115-2119. NMR studies of full length human p53 with four stabilising mutations in the core domain. This paper describes interactions between core domains for free p53 and in complex with DNA.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.7
, pp. 2115-2119
-
-
Veprintsev, D.B.1
Freund, S.M.2
Andreeva, A.3
Rutledge, S.E.4
Tidow, H.5
Cañadillas, J.M.6
Blair, C.M.7
Fersht, A.R.8
-
12
-
-
0027749169
-
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein
-
Bargonetti J., Manfredi J.J., Chen X., Marshak D.R., and Prives C. A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev 7 12B (1993) 2565-2574
-
(1993)
Genes Dev
, vol.7
, Issue.12 B
, pp. 2565-2574
-
-
Bargonetti, J.1
Manfredi, J.J.2
Chen, X.3
Marshak, D.R.4
Prives, C.5
-
13
-
-
0027771333
-
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots
-
Pavletich N.P., Chambers K.A., and Pabo C.O. The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots. Genes Dev 7 12B (1993) 2556-2564
-
(1993)
Genes Dev
, vol.7
, Issue.12 B
, pp. 2556-2564
-
-
Pavletich, N.P.1
Chambers, K.A.2
Pabo, C.O.3
-
14
-
-
0026849821
-
Definition of a consensus binding site for p53
-
el-Deiry W.S., Kern S.E., Pietenpol J.A., Kinzler K.W., and Vogelstein B. Definition of a consensus binding site for p53. Nat Genet 1 1 (1992) 45-49
-
(1992)
Nat Genet
, vol.1
, Issue.1
, pp. 45-49
-
-
el-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
15
-
-
0026650531
-
A transcriptionally active DNA-binding site for human p53 protein complexes
-
Funk W.D., Pak D.T., Karas R.H., Wright W.E., and Shay J.W. A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol 12 6 (1992) 2866-2871
-
(1992)
Mol Cell Biol
, vol.12
, Issue.6
, pp. 2866-2871
-
-
Funk, W.D.1
Pak, D.T.2
Karas, R.H.3
Wright, W.E.4
Shay, J.W.5
-
16
-
-
0028145057
-
p53 tagged sites from human genomic DNA
-
Tokino T., Thiagalingam S., el-Deiry W.S., Waldman T., Kinzler K.W., and Vogelstein B. p53 tagged sites from human genomic DNA. Hum Mol Genet 3 9 (1994) 1537-1542
-
(1994)
Hum Mol Genet
, vol.3
, Issue.9
, pp. 1537-1542
-
-
Tokino, T.1
Thiagalingam, S.2
el-Deiry, W.S.3
Waldman, T.4
Kinzler, K.W.5
Vogelstein, B.6
-
17
-
-
0027521114
-
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants
-
Halazonetis T.D., and Kandil A.N. Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. EMBO J 12 13 (1993) 5057-5064
-
(1993)
EMBO J
, vol.12
, Issue.13
, pp. 5057-5064
-
-
Halazonetis, T.D.1
Kandil, A.N.2
-
18
-
-
0034862475
-
The C-terminus of p53: the more you learn the less you know
-
Ahn J., and Prives C. The C-terminus of p53: the more you learn the less you know. Nat Struct Biol 8 9 (2001) 730-732
-
(2001)
Nat Struct Biol
, vol.8
, Issue.9
, pp. 730-732
-
-
Ahn, J.1
Prives, C.2
-
19
-
-
6444245364
-
p53 latency-out of the blind alley
-
Yakovleva T., Pramanik A., Terenius L., Ekstrom T.J., and Bakalkin G. p53 latency-out of the blind alley. Trends Biochem Sci 27 12 (2002) 612-618
-
(2002)
Trends Biochem Sci
, vol.27
, Issue.12
, pp. 612-618
-
-
Yakovleva, T.1
Pramanik, A.2
Terenius, L.3
Ekstrom, T.J.4
Bakalkin, G.5
-
20
-
-
0041384333
-
The N-terminal domain of p53 is natively unfolded
-
Dawson R., Müller L., Dehner A., Klein C., Kessler H., and Buchner J. The N-terminal domain of p53 is natively unfolded. J Mol Biol 332 5 (2003) 1131-1141
-
(2003)
J Mol Biol
, vol.332
, Issue.5
, pp. 1131-1141
-
-
Dawson, R.1
Müller, L.2
Dehner, A.3
Klein, C.4
Kessler, H.5
Buchner, J.6
-
21
-
-
0028812627
-
Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein
-
Chang J., Kim D.H., Lee S.W., Choi K.Y., and Sung Y.C. Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein. J Biol Chem 270 42 (1995) 25014-25019
-
(1995)
J Biol Chem
, vol.270
, Issue.42
, pp. 25014-25019
-
-
Chang, J.1
Kim, D.H.2
Lee, S.W.3
Choi, K.Y.4
Sung, Y.C.5
-
22
-
-
0030448650
-
Identification of a novel p53 functional domain that is necessary for efficient growth suppression
-
Walker K.K., and Levine A.J. Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proc Natl Acad Sci U S A 93 26 (1996) 15335-15340
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.26
, pp. 15335-15340
-
-
Walker, K.K.1
Levine, A.J.2
-
23
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie P.H., Gorina S., Marechal V., Elenbaas B., Moreau J., Levine A.J., and Pavletich N.P. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 274 5289 (1996) 948-953
-
(1996)
Science
, vol.274
, Issue.5289
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
Pavletich, N.P.7
-
24
-
-
27344449049
-
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A
-
X-ray crystallography and NMR studies of the p53 N-terminal domain in complex with RPA suggest a novel mechanism for protein-protein interaction based on DNA mimicry.
-
Bochkareva E., Kaustov L., Ayed A., Yi G.S., Lu Y., Pineda-Lucena A., Liao J.C., Okorokov A.L., Milner J., Arrowsmith C.H., and Bochkarev A. Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proc Natl Acad Sci U S A 102 (2005) 15412-15417. X-ray crystallography and NMR studies of the p53 N-terminal domain in complex with RPA suggest a novel mechanism for protein-protein interaction based on DNA mimicry.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15412-15417
-
-
Bochkareva, E.1
Kaustov, L.2
Ayed, A.3
Yi, G.S.4
Lu, Y.5
Pineda-Lucena, A.6
Liao, J.C.7
Okorokov, A.L.8
Milner, J.9
Arrowsmith, C.H.10
Bochkarev, A.11
-
25
-
-
0034704175
-
The N terminus of p53 regulates its dissociation from DNA
-
Cain C., Miller S., Ahn J., and Prives C. The N terminus of p53 regulates its dissociation from DNA. J Biol Chem 275 51 (2000) 39944-39953
-
(2000)
J Biol Chem
, vol.275
, Issue.51
, pp. 39944-39953
-
-
Cain, C.1
Miller, S.2
Ahn, J.3
Prives, C.4
-
26
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
-
Cho Y., Gorina S., Jeffrey P.D., and Pavletich N.P. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265 5170 (1994) 346-355
-
(1994)
Science
, vol.265
, Issue.5170
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
27
-
-
0030575866
-
Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2
-
Gorina S., and Pavletich N.P. Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science 274 5289 (1996) 1001-1005
-
(1996)
Science
, vol.274
, Issue.5289
, pp. 1001-1005
-
-
Gorina, S.1
Pavletich, N.P.2
-
28
-
-
0035853734
-
Crystal structure of the mouse p53 core DNA-binding domain at 2, 7 A resolution
-
Zhao K., Chai X., Johnston K., Clements A., and Marmorstein R. Crystal structure of the mouse p53 core DNA-binding domain at 2, 7 A resolution. J Biol Chem 276 15 (2001) 12107-12120
-
(2001)
J Biol Chem
, vol.276
, Issue.15
, pp. 12107-12120
-
-
Zhao, K.1
Chai, X.2
Johnston, K.3
Clements, A.4
Marmorstein, R.5
-
29
-
-
0037099666
-
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
-
Derbyshire D.J., Basu B.P., Serpell L.C., Joo W.S., Date T., Iwabuchi K., and Doherty A.J. Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor. EMBO J 21 14 (2002) 3863-3872
-
(2002)
EMBO J
, vol.21
, Issue.14
, pp. 3863-3872
-
-
Derbyshire, D.J.1
Basu, B.P.2
Serpell, L.C.3
Joo, W.S.4
Date, T.5
Iwabuchi, K.6
Doherty, A.J.7
-
30
-
-
0036500691
-
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure
-
Joo W.S., Jeffrey P.D., Cantor S.B., Finnin M.S., Livingston D.M., and Pavletich N.P. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev 16 5 (2002) 583-593
-
(2002)
Genes Dev
, vol.16
, Issue.5
, pp. 583-593
-
-
Joo, W.S.1
Jeffrey, P.D.2
Cantor, S.B.3
Finnin, M.S.4
Livingston, D.M.5
Pavletich, N.P.6
-
31
-
-
3142642685
-
Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1
-
Huyen Y., Jeffrey P.D., Derry W.B., Rothman J.H., Pavletich N.P., Stavridi E.S., and Halazonetis T.D. Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1. Structure 12 7 (2004) 1237-1243
-
(2004)
Structure
, vol.12
, Issue.7
, pp. 1237-1243
-
-
Huyen, Y.1
Jeffrey, P.D.2
Derry, W.B.3
Rothman, J.H.4
Pavletich, N.P.5
Stavridi, E.S.6
Halazonetis, T.D.7
-
32
-
-
33746002633
-
Structure of the p53 Core Domain Dimer Bound to DNA
-
Ho W.C., Fitzgerald M.X., and Marmorstein R. Structure of the p53 Core Domain Dimer Bound to DNA. J Biol Chem 281 (2006) 20494-20502
-
(2006)
J Biol Chem
, vol.281
, pp. 20494-20502
-
-
Ho, W.C.1
Fitzgerald, M.X.2
Marmorstein, R.3
-
33
-
-
47649096991
-
Structural biology of the tumor suppressor p53
-
A wide-ranging review on structural biology of p53 that brings together biophysical and biochemical data obtained during the past decade.
-
Joerger A.C., and Fersht A.R. Structural biology of the tumor suppressor p53. Annu Rev Biochem 77 (2008) 557-582. A wide-ranging review on structural biology of p53 that brings together biophysical and biochemical data obtained during the past decade.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 557-582
-
-
Joerger, A.C.1
Fersht, A.R.2
-
34
-
-
0028952841
-
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1, 7 angstroms
-
Jeffrey P.D., Gorina S., and Pavletich N.P. Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1, 7 angstroms. Science 267 5203 (1995) 1498-1502
-
(1995)
Science
, vol.267
, Issue.5203
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina, S.2
Pavletich, N.P.3
-
35
-
-
0028965832
-
Refined solution structure of the oligomerization domain of the tumour suppressor p53
-
Clore G.M., Ernst J., Clubb R., Omichinski J.G., Kennedy W.M., Sakaguchi K., Appella E., and Gronenborn A.M. Refined solution structure of the oligomerization domain of the tumour suppressor p53. Nat Struct Biol 2 4 (1995) 321-333
-
(1995)
Nat Struct Biol
, vol.2
, Issue.4
, pp. 321-333
-
-
Clore, G.M.1
Ernst, J.2
Clubb, R.3
Omichinski, J.G.4
Kennedy, W.M.5
Sakaguchi, K.6
Appella, E.7
Gronenborn, A.M.8
-
36
-
-
0027174586
-
Use of the two-hybrid system to identify the domain of p53 involved in oligomerization
-
Iwabuchi K., Li B., Bartel P., and Fields S. Use of the two-hybrid system to identify the domain of p53 involved in oligomerization. Oncogene 8 6 (1993) 1693-1696
-
(1993)
Oncogene
, vol.8
, Issue.6
, pp. 1693-1696
-
-
Iwabuchi, K.1
Li, B.2
Bartel, P.3
Fields, S.4
-
37
-
-
10744233648
-
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation
-
Mujtaba S., He Y., Zeng L., Yan S., Plotnikova O., Sachchidanand, Sanchez R., Zeleznik-Le N.J., Ronai Z., and Zhou M.M. Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Mol Cell 13 (2004) 251-263
-
(2004)
Mol Cell
, vol.13
, pp. 251-263
-
-
Mujtaba, S.1
He, Y.2
Zeng, L.3
Yan, S.4
Plotnikova, O.5
Sachchidanand6
Sanchez, R.7
Zeleznik-Le, N.J.8
Ronai, Z.9
Zhou, M.M.10
-
38
-
-
0036753953
-
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
-
Avalos J.L., Celic I., Muhammad S., Cosgrove M.S., Boeke J.D., and Wolberger C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Mol Cell 10 3 (2002) 523-535
-
(2002)
Mol Cell
, vol.10
, Issue.3
, pp. 523-535
-
-
Avalos, J.L.1
Celic, I.2
Muhammad, S.3
Cosgrove, M.S.4
Boeke, J.D.5
Wolberger, C.6
-
39
-
-
0033945124
-
Structure of the negative regulatory domain of p53 bound to S100B(betabeta)
-
Rustandi R.R., Baldisseri D.M., and Weber D.J. Structure of the negative regulatory domain of p53 bound to S100B(betabeta). Nat Struct Biol 7 (2000) 570-574
-
(2000)
Nat Struct Biol
, vol.7
, pp. 570-574
-
-
Rustandi, R.R.1
Baldisseri, D.M.2
Weber, D.J.3
-
40
-
-
33745209412
-
Structural basis of DNA recognition by p53 tetramers
-
Several crystal structures of the p53 core domain in complex with different specific DNA targets. The paper extends previous studies and provides a detailed analysis of the p53-DNA interaction.
-
Kitayner M., Rozenberg H., Kessler N., Rabinovich D., Shaulov L., Haran T.E., and Shakked Z. Structural basis of DNA recognition by p53 tetramers. Mol Cell 22 (2006) 741-753. Several crystal structures of the p53 core domain in complex with different specific DNA targets. The paper extends previous studies and provides a detailed analysis of the p53-DNA interaction.
-
(2006)
Mol Cell
, vol.22
, pp. 741-753
-
-
Kitayner, M.1
Rozenberg, H.2
Kessler, N.3
Rabinovich, D.4
Shaulov, L.5
Haran, T.E.6
Shakked, Z.7
-
41
-
-
33750486164
-
The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity
-
The first structural analysis of the full length murine p53 protein using cryo-EM and single particle analysis. The results suggest a new model for organisation of the p53 tetramer.
-
Okorokov A.L., Sherman M.B., Plisson C., Grinkevich V., Sigmundsson K., Selivanova G., Milner J., and Orlova E.V. The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity. EMBO J 25 21 (2006) 5191-5200. The first structural analysis of the full length murine p53 protein using cryo-EM and single particle analysis. The results suggest a new model for organisation of the p53 tetramer.
-
(2006)
EMBO J
, vol.25
, Issue.21
, pp. 5191-5200
-
-
Okorokov, A.L.1
Sherman, M.B.2
Plisson, C.3
Grinkevich, V.4
Sigmundsson, K.5
Selivanova, G.6
Milner, J.7
Orlova, E.V.8
-
42
-
-
34547634446
-
Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex
-
Structural analysis of the full length stabilised human p53 protein using a combination of NMR spectroscopy, negative stain electron microscopy and SAXS analysis.
-
Tidow H., Melero R., Mylonas E., Freund S.M., Grossmann J.G., Carazo J.M., Svergun D.I., Valle M., and Fersht A.R. Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex. Proc Natl Acad Sci U S A 104 30 (2007) 12324-12329. Structural analysis of the full length stabilised human p53 protein using a combination of NMR spectroscopy, negative stain electron microscopy and SAXS analysis.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.30
, pp. 12324-12329
-
-
Tidow, H.1
Melero, R.2
Mylonas, E.3
Freund, S.M.4
Grossmann, J.G.5
Carazo, J.M.6
Svergun, D.I.7
Valle, M.8
Fersht, A.R.9
-
43
-
-
0032579321
-
The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability
-
Hansen S., Lane D.P., and Midgley C.A. The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability. J Mol Biol 275 4 (1998) 575-588
-
(1998)
J Mol Biol
, vol.275
, Issue.4
, pp. 575-588
-
-
Hansen, S.1
Lane, D.P.2
Midgley, C.A.3
-
44
-
-
0032568539
-
Identification of an additional negative regulatory region for p53 sequence-specific DNA binding
-
Muller-Tiemann B.F., Halazonetis T.D., and Elting J.J. Identification of an additional negative regulatory region for p53 sequence-specific DNA binding. Proc Natl Acad Sci U S A 95 11 (1998) 6079-6084
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.11
, pp. 6079-6084
-
-
Muller-Tiemann, B.F.1
Halazonetis, T.D.2
Elting, J.J.3
-
45
-
-
0026448672
-
Regulation of the specific DNA binding function of p53
-
Hupp T.R., Meek D.W., Midgley C.A., and Lane D.P. Regulation of the specific DNA binding function of p53. Cell 71 5 (1992) 875-886
-
(1992)
Cell
, vol.71
, Issue.5
, pp. 875-886
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
46
-
-
0028908796
-
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
-
Horikoshi N., Usheva A., Chen J., Levine A.J., Weinmann R., and Shenk T. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Mol Cell Biol 15 1 (1995) 227-234
-
(1995)
Mol Cell Biol
, vol.15
, Issue.1
, pp. 227-234
-
-
Horikoshi, N.1
Usheva, A.2
Chen, J.3
Levine, A.J.4
Weinmann, R.5
Shenk, T.6
-
47
-
-
0030054869
-
Dissection of functional domains of the human DNA replication protein complex replication protein A
-
Lin Y.L., Chen C., Keshav K.F., Winchester E., and Dutta A. Dissection of functional domains of the human DNA replication protein complex replication protein A. J Biol Chem 271 29 (1996) 17190-17198
-
(1996)
J Biol Chem
, vol.271
, Issue.29
, pp. 17190-17198
-
-
Lin, Y.L.1
Chen, C.2
Keshav, K.F.3
Winchester, E.4
Dutta, A.5
-
48
-
-
64549155867
-
Crystal structure of a p53 core tetramer bound to DNA
-
[Epub ahead of print]
-
Malecka K.A., Ho W.C., and Marmorstein R. Crystal structure of a p53 core tetramer bound to DNA. Oncogene (2008 November 3) [Epub ahead of print]
-
(2008)
Oncogene
-
-
Malecka, K.A.1
Ho, W.C.2
Marmorstein, R.3
-
49
-
-
0028606859
-
p53 oligomerization and DNA looping are linked with transcriptional activation
-
Stenger J.E., Tegtmeyer P., Mayr G.A., Reed M., Wang Y., Wang P., Hough P.V., and Mastrangelo I.A. p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J 13 24 (1994) 6011-6020
-
(1994)
EMBO J
, vol.13
, Issue.24
, pp. 6011-6020
-
-
Stenger, J.E.1
Tegtmeyer, P.2
Mayr, G.A.3
Reed, M.4
Wang, Y.5
Wang, P.6
Hough, P.V.7
Mastrangelo, I.A.8
-
50
-
-
0032518907
-
Synergistic transcriptional activation of the MCK promoter by p53: tetramers link separated DNA response elements by DNA looping
-
Jackson P., Mastrangelo I., Reed M., Tegtmeyer P., Yardley G., and Barrett J. Synergistic transcriptional activation of the MCK promoter by p53: tetramers link separated DNA response elements by DNA looping. Oncogene 16 2 (1998) 283-292
-
(1998)
Oncogene
, vol.16
, Issue.2
, pp. 283-292
-
-
Jackson, P.1
Mastrangelo, I.2
Reed, M.3
Tegtmeyer, P.4
Yardley, G.5
Barrett, J.6
-
51
-
-
8644241631
-
p53 linear diffusion along DNA requires its C terminus
-
McKinney K., Mattia M., Gottifredi V., and Prives C. p53 linear diffusion along DNA requires its C terminus. Mol Cell 16 3 (2004) 413-424
-
(2004)
Mol Cell
, vol.16
, Issue.3
, pp. 413-424
-
-
McKinney, K.1
Mattia, M.2
Gottifredi, V.3
Prives, C.4
-
52
-
-
0034881964
-
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
-
Espinosa J.M., and Emerson B.M. Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment. Mol Cell 8 1 (2001) 57-69
-
(2001)
Mol Cell
, vol.8
, Issue.1
, pp. 57-69
-
-
Espinosa, J.M.1
Emerson, B.M.2
-
53
-
-
0036784608
-
Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein
-
McKinney K., and Prives C. Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein. Mol Cell Biol 22 19 (2002) 6797-6808
-
(2002)
Mol Cell Biol
, vol.22
, Issue.19
, pp. 6797-6808
-
-
McKinney, K.1
Prives, C.2
-
54
-
-
37249038565
-
p53 family isoforms
-
Bourdon J.C. p53 family isoforms. Curr Pharm Biotechnol 8 6 (2007) 332-336
-
(2007)
Curr Pharm Biotechnol
, vol.8
, Issue.6
, pp. 332-336
-
-
Bourdon, J.C.1
-
55
-
-
3543110350
-
p63 and p73: roles in development and tumor formation
-
Moll U.M., and Slade N. p63 and p73: roles in development and tumor formation. Mol Cancer Res 2 7 (2004) 371-386
-
(2004)
Mol Cancer Res
, vol.2
, Issue.7
, pp. 371-386
-
-
Moll, U.M.1
Slade, N.2
-
56
-
-
0028943706
-
Interaction of p53 with its consensus DNA-binding site
-
Wang Y., Schwedes J.F., Parks D., Mann K., and Tegtmeyer P. Interaction of p53 with its consensus DNA-binding site. Mol Cell Biol 15 4 (1995) 2157-2165
-
(1995)
Mol Cell Biol
, vol.15
, Issue.4
, pp. 2157-2165
-
-
Wang, Y.1
Schwedes, J.F.2
Parks, D.3
Mann, K.4
Tegtmeyer, P.5
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