MDR1/P-gp and VEGF synergistically enhance the invasion of Hep-2 cells with multidrug resistance induced by taxol

Annals of Surgical Oncology

Volumn 16, Issue 5, 2009, Pages 1421-1428

  Li, Li ^a   Jiang, Alice C ^b   Dong, Pin ^c   Wang, Haibo ^a   Xu, Wei ^a   Xu, Chengzhi ^c  

^a Department of Otolaryngology Head and Neck Surgery   (China)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; SMALL INTERFERING RNA; SU 1498; UNCLASSIFIED DRUG; VASCULOTROPIN 165; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 2;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER INVASION; CANCER RESISTANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; GENE OVEREXPRESSION; HEP 2 CELL; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION; RNA INTERFERENCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; LARYNGEAL NEOPLASMS; NEOPLASM INVASIVENESS; P-GLYCOPROTEIN; PACLITAXEL; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 64249150262     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-009-0395-7     Document Type: Article

References (35)

1. Y Liang L O'Driscoll S McDonnell P Doolan I Oglesby K Duffy 2004 Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs Int J Cancer. 111 484 493
2. Y Liang S McDonnell M Clynes 2002 Examining the relationship between cancer invasion/metastasis and drug resistance Curr Cancer Drug Targets. 2 257 277
3. AF Chambers AC Groom IC MacDonald 2002 Dissemination and growth of cancer cells in metastatic sites Nat Rev Cancer. 2 563 572
4. YA DeClerck S Imren AM Montgomery 1997 Proteases and protease inhibitors in tumor progression Adv Exp Med Biol. 425 89 97
5. I Stamenkovic 2000 Matrix metalloproteinases in tumor invasion and metastasis Semin Cancer Biol. 10 415 433
6. WJ Lamoreaux ME Fitzgerald A Reiner 1998 Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro Microvasc Res. 55 29 42
7. Y Liang P Meleady I Cleary 2001 Selection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness Eur J Cancer. 37 1041 1052
8. M Osmak D Niksic A Brozovic 1999 Drug resistant tumor cells have increased levels of tumor markers for invasion and metastasis Anticancer Res. 19 3193 3197
9. C Cillo V Ling RP Hill 1989 Drug resistance in KHT fibrosarcoma cell lines with different metastatic ability Int J Cancer. 43 107 111
10. C Cillo JE Dick V Ling 1987 Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines Cancer Res. 47 2604 2608
11. K Scotlandi M Serra G Nicoletti 1996 Multidrug resistance and malignancy in human osteosarcoma Cancer Res. 56 2434 2439
12. EE Vokes RR Weichselbaum SM Lippman 1993 Head and neck cancer N Engl J Med. 328 184 194
13. P O-charoenrat H Modjtahedi P Rhys-Evans 2000 Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells Cancer Res. 60 1121 1128
14. L Li AC Jiang P Dong 2007 The characteristics of Hep-2 cell with multiple drug resistance induced by Taxol Otolaryngol Head Neck Surg. 137 659 664
15. KE Miletti-Gonzalez S Chen N Muthukumaran 2005 The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer Cancer Res. 65 6660 6667
16. H Wu WN Hait JM Yang 2003 Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells Cancer Res. 63 1515 1519
17. KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods. 25 402 408
18. G Boguslawski PW McGlynn KA Harvey 2004 SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro J Biol Chem. 279 5716 5724
19. J Crown M O'Leary 2000 The taxanes: an update Lancet. 355 1176 1178
20. BS Glisson BA Murphy G Frenette 2002 Phase II Trial of docetaxel and cisplatin combination chemotherapy in patients with squamous cell carcinoma of the head and neck J Clin Oncol. 20 1593 1599
21. GE Morozevich NI Kozlova ME Preobrazhenskaya 2006 The role of beta1 integrin subfamily in anchorage-dependent apoptosis of breast carcinoma cells differing in multidrug resistance Biochemistry (Mosc) 71 489 495
22. JM Yang Z Xu H Wu 2003 Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells Mol Cancer Res. 1 420 427
23. RS Weinstein SM Jakate JM Dominguez 1991 Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis Cancer Res. 51 2720 2726
24. J Schneider S Gonzalez-Roces M Pollan 2001 Expression of LRP and MDR1 in locally advanced breast cancer predicts axillary node invasion at the time of rescue mastectomy after induction chemotherapy Breast Cancer Res. 3 183 191
25. H Yabushita M Shimazu M Noguchi 2003 Vascular endothelial growth factor activating matrix metalloproteinase in ascitic fluid during peritoneal dissemination of ovarian cancer Oncol Rep. 10 89 95
26. JL Owen V Iragavarapu-Charyulu Z Gunja-Smith 2003 Up-regulation of matrix metalloproteinase-9 in T lymphocytes of mammary tumor bearers: role of vascular endothelial growth factor J Immunol. 171 4340 4351
27. N Ferrara HP Gerber J LeCouter 2003 The biology of VEGF and its receptors Nat Med. 9 669 676
28. G Neufeld T Cohen S Gengrinovitch 1999 Vascular endothelial growth factor (VEGF) and its receptors FASEB J. 13 9 22
29. Y Wang W Kong J Yue 2006 Vascular endothelial growth factor165-regulated nasopharyngeal carcinoma cell lines invasion and migration involve expression and activation of matrix metalloproteinase-2 J Huazhong Univ Sci Technolog Med Sci 26 621 624
30. FQ Wang J So S Reierstad 2006 Vascular endothelial growth factor-regulated ovarian cancer invasion and migration involves expression and activation of matrix metalloproteinases Int J Cancer. 118 879 888
31. ER Sauter M Nesbit JC Watson 1999 Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck Clin Cancer Res. 5 775 782
32. L Tao L Zhou L Zheng 2006 Elemene displays anti-cancer ability on laryngeal cancer cells in vitro and in vivo Cancer Chemother Pharmacol. 58 24 34
33. W Fiedler U Graeven S Ergun 1997 Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia Blood. 89 1870 1875
34. PA Kyzas D Stefanou A Batistatou 2005 Potential autocrine function of vascular endothelial growth factor in head and neck cancer via vascular endothelial growth factor receptor-2 Mod Pathol. 18 485 494
35. G Klement P Huang B Mayer 2002 Differences in therapeutic indexes of combination metronomic chemotherapy and an anti-VEGFR-2 antibody in multidrug-resistant human breast cancer xenografts Clin Cancer Res. 8 221 232