Intrathecal transplantation of autologous macrophages genetically modified to secrete proenkephalin ameliorated hyperalgesia and allodynia following peripheral nerve injury in rats

Neuroscience Research

Volumn 64, Issue 1, 2009, Pages 56-62

  Hino, Masayuki ^a   Ogata, Tadanori ^a   Morino, Tadao ^a   Horiuchi, Hideki ^a   Yamamoto, Haruyasu ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Allodynia; Gene transfer; Hyperalgesia; Macrophage; Neuropathic pain; Proenkephalin

Indexed keywords

PROENKEPHALIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOTRANSPLANTATION; CONTROLLED STUDY; ELECTROPORATION; GENE THERAPY; GENE TRANSFER; HYPERALGESIA; MACROPHAGE; MALE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT;

ANIMALS; CELLS, CULTURED; ENKEPHALIN, METHIONINE; ENKEPHALINS; HOT TEMPERATURE; HUMANS; HYPERALGESIA; INJECTIONS, SPINAL; MACROPHAGES; MALE; PAIN; PAIN MEASUREMENT; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RNA, MESSENGER; SCIATIC NEUROPATHY; SPINAL CORD; TIME FACTORS; TRANSFECTION; TRANSPLANTATION, AUTOLOGOUS;

EID: 64249128656     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2009.01.011     Document Type: Article

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