Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 296, Issue 3, 2009, Pages

  Cavarra, Eleonora ^a   Fardin, Paolo ^b   Fineschi, Silvia ^a   Ricciardi, Annamaria ^b   De Cunto, Giovanna ^a   Sallustio, Fabio ^b   Zorzetto, Michele ^c   Luisetti, Maurizio ^c   Pfeffer, Ulrich ^d   Lungarella, Giuseppe ^a   Varesio, Luigi ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b G GASLINI INSTITUTE   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

Antioxidant defenses; Cigarette smoke susceptibility; Emphysema; Microarrays; Mouse strains

Indexed keywords

CIGARETTE SMOKE; PRIMER DNA;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CELL ADHESION; CONTROLLED STUDY; DBA 2 MOUSE; EARLY RESPONSE GENE; EMPHYSEMA; ENVIRONMENTAL EXPOSURE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC RESISTANCE; GENETIC SUSCEPTIBILITY; LONG TERM EXPOSURE; LUNG INJURY; LUNG RESISTANCE; MALE; MICROARRAY ANALYSIS; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPARATIVE STUDY; DBA MOUSE; DISEASE MODEL; DNA MICROARRAY; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; LUNG; METABOLISM; MULTIGENE FAMILY; PATHOLOGY; RISK FACTOR; SMOKING; SPECIES DIFFERENCE;

ANIMALS; BASE SEQUENCE; DISEASE MODELS, ANIMAL; DNA PRIMERS; GENE EXPRESSION PROFILING; HUMANS; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED ICR; MULTIGENE FAMILY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK FACTORS; SMOKING; SPECIES SPECIFICITY;

EID: 64249111192     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90382.2008     Document Type: Article

References (48)

1. Atzori L, Lucattelli M, Bartalesi B, Johns R, Chambers R, Lungarella G. Role of PAR-1 in the development of goblet cell metaplasia (Abstract). Third International Conference on Animal Models of COPD, Certosa di Pontignano, Siena, September 24-26, 2005.
2. Barnes PJ. Genetics and pulmonary medicine. 9. Molecular genetics of chronic obstructive pulmonary disease. Thorax 54: 245-252, 1999.
3. Bartalesi B, Cavarra E, Fineschi S, Lucattelli M, Lunghi B, Martorana PA, Lungarella G. Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants. Eur Respir J 25: 15-22, 2005. (Pubitemid 40207726)
4. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc B 57: 289-300, 1995.
5. Bosio A, Knorr C, Janssen U, Gebel S, Haussmann HJ, Muller T. Kinetics of gene expression profiling in Swiss 3T3 cells exposed to aqueous extracts of cigarette smoke. Carcinogenesis 23: 741-748, 2002. (Pubitemid 34567512)
6. Brown MD, Forsythe AB. Robust tests for equality of variances. J Am Stat Assoc 69: 364-367, 1974.
7. Cavarra E, Bartalesi B, Lucattelli M, Fineschi S, Lunghi B, Gambelli F, Ortiz LA, Martorana PA, Lungarella G. Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants. Am J Respir Crit Care Med 164: 886-890, 2001. (Pubitemid 32881929)
8. da Hora K, Valenca SS, Porto LC. Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke. Exp Lung Res 31: 759-770, 2005.
9. Dalle-Donne I, Scaloni A, Giustarini D, Cavarra E, Tell G, Lungarella G, Colombo R, Rossi R, Milzani A. Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics. Mass Spectrom Rev 24: 55-99, 2005.
10. Dinkova-Kostova AT, Talalay P. Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen. Free Radic Biol Med 29: 231-240, 2000.
11. Fletcher C, Peto R. The natural history of chronic airflow obstruction. Br Med J 1: 1645-1648, 1977. (Pubitemid 8124466)
12. Gautier L, Cope L, Bolstad BM, Irizarry RA. affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20: 307-315, 2004. (Pubitemid 38262761)
13. Golpon HA, Coldren CD, Zamora MR, Cosgrove GP, Moore MD, Tuder RM, Geraci MW, Voelkel NF. Emphysema lung tissue gene expression profiling. Am J Respir Cell Mol Biol 31: 595-600, 2004.
14. Gupta V, Galante A, Soteropoulos P, Guo S, Wagner BJ. Global gene profiling reveals novel glucocorticoid induced changes in gene expression of human lens epithelial cells. Mol Vis 11: 1018-1040, 2005. (Pubitemid 41672497)
15. Heguy A, O'Connor TP, Luettich K, Worgall S, Cieciuch A, Harvey BG, Hackett NR, Crystal RG. Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking. J Mol Med 84: 318-328, 2006.
16. Hui W, Gel YR, Gastwirth JL. lawstat: An R Package for Law, Public Policy and Biostatistics. J Stat Softw 28: 2008.
17. Kendziorski CM, Zhang Y, Lan H, Attie AD. The efficiency of pooling mRNA in microarray experiments. Biostatistics 4: 465-477, 2003. (Pubitemid 36810097)
18. Lee KM, Kim JH, Kang D. Design issues in toxicogenomics using DNA microarray experiment. Toxicol Appl Pharmacol 207, Suppl 2: 200-208, 2005.
19. Lee KY, Ito K, Hayashi R, Jazrawi EP, Barnes PJ, Adcock IM. NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. J Immunol 176: 603-615, 2006. (Pubitemid 43023309)
20. Levene H. Robust tests for equality of variances. In: Contributions to Probability and Statistics: Essays in Honor of Harold Hotelling, edited by Olkin I, Ghurye S, Hoeffding W, Madow W, and Mann H. Palo Alto, CA: Stanford Univ. Press, 1960, p. 278-292.
21. Lucattelli M, Bartalesi B, Cavarra E, Fineschi S, Lunghi B, Martorana PA, Lungarella G. Is neutrophil elastase the missing link between emphysema and fibrosis? Respir Res 6: 97, 2005.
22. Macnee W, Rahman I. Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160: S58-S65, 1999.
23. Mahadeva R, Shapiro SD. Chronic obstructive pulmonary disease * 3: Experimental animal models of pulmonary emphysema. Thorax 57: 908-914, 2002. (Pubitemid 35178618)
24. Martorana PA, Cavarra E, Lucattelli M, Lungarella G. Models for COPD involving cigarette smoke. Drug Discov Today Dis Models 3: 225-230, 2006.
25. 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 12: 2005-2015, 1993.
26. Muller PY, Janovjak H, Miserez AR, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 32: 1372-4, 1376, 1378-1379, 2002. (Pubitemid 34619770)
27. Murakami S, Nagaya N, Itoh T, Iwase T, Fujisato T, Nishioka K, Hamada K, Kangawa K, Kimura H. Adrenomedullin regenerates alveoli and vasculature in elastase-induced pulmonary emphysema in mice. Am J Respir Crit Care Med 172: 581-589, 2005. (Pubitemid 41232969)
28. Osburn WO, Wakabayashi N, Misra V, Nilles T, Biswal S, Trush MA, Kensler TW. Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion. Arch Biochem Biophys 454: 7-15, 2006. (Pubitemid 44427746)
29. Papaiahgari S, Yerrapureddy A, Reddy SR, Reddy NM, Dodd O, Crow MT, Grigoryev DN, Barnes K, Tuder RM, Yamamoto M, Kensler TW, Biswal S, Mitzner W, Hassoun PM, Reddy SP. Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. Am J Respir Crit Care Med 176: 1222-1235, 2007. (Pubitemid 350256476)
30. Papi A, Luppi F, Franco F, Fabbri LM. Pathophysiology of exacerbations of Chronic Obstructive Pulmonary Disease. Proc Am Thorac Soc 3: 245-251, 2006. (Pubitemid 43668189)
31. Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 163: 1256-1276, 2001.
32. R Development Core Team. R: A Language and Environment for Statistical Computing. (Online) R Foundation for Statistical Computing, Vienna, Austria, 2004. http://www.R-project.org.
33. Rahman I, Macnee W. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. Am J Physiol Lung Cell Mol Physiol 277: L1067-L1088, 1999. (Pubitemid 30046033)
34. Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 114: 1248-1259, 2004. (Pubitemid 40385296)
35. Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, Yamamoto M, Kensler TW, Tuder RM, Georas SN, Biswal S. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med 202: 47-59, 2005. (Pubitemid 41002909)
36. Sandford AJ, Weir TD, Pare PD. Genetic risk factors for chronic obstructive pulmonary disease. Eur Respir J 10: 1380-1391, 1997.
37. Shapiro SD. Matrix metalloproteinase degradation of extracellular matrix: biological consequences. Curr Opin Cell Biol 10: 602-608, 1998.
38. Shapiro SD, Demeo DL, Silverman EK. Smoke and mirrors: mouse models as a reflection of human chronic obstructive pulmonary disease. Am J Respir Crit Care Med 170: 929-931, 2004.
39. Sies H, Arteel GE. Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics. Free Radic Biol Med 28: 1451-1455, 2000. (Pubitemid 30604226)
40. Singh A, Rangasamy T, Thimmulappa RK, Lee H, Osburn WO, Brigelius-Flohe R, Kensler TW, Yamamoto M, Biswal S. Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2. Am J Respir Cell Mol Biol 35: 639-650, 2006.
41. Takeuchi T, Misaki A, Fujita J, Sonobe H, Ohtusuki Y. T-cadherin (CDH13, H-cadherin) expression downregulated surfactant protein D in bronchioloalveolar cells. Virchows Arch 438: 370-375, 2001. (Pubitemid 32285362)
42. Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J Clin Invest 116: 984-995, 2006.
43. Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema. The missing link. Am J Respir Cell Mol Biol 28: 551-554, 2003. (Pubitemid 36543401)
44. Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proc Am Thorac Soc 3: 503-510, 2006. (Pubitemid 44285536)
45. Wert SE, Yoshida M, LeVine AM, Ikegami M, Jones T, Ross GF, Fisher JH, Korfhagen TR, Whitsett JA. Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc Natl Acad Sci USA 97: 5972-5977, 2000. (Pubitemid 30367508)
46. Yao H, Yang SR, Kode A, Rajendrasozhan S, Caito S, Adenuga D, Henry R, Edirisinghe I, Rahman I. Redox regulation of lung inflammation: role of NADPH oxidase and NF-kappaB signalling. Biochem Soc Trans 35: 1151-1155, 2007. (Pubitemid 350206448)
47. Yoneda K, Chang MM, Chmiel K, Chen Y, Wu R. Application of high-density DNA microarray to study smoke- and hydrogen peroxide-induced injury and repair in human bronchial epithelial cells. J Am Soc Nephrol 14: S284-S289, 2003. (Pubitemid 36903941)
48. Young IS, Woodside JV. Antioxidants in health and disease. J Clin Pathol 54: 176-186, 2001.