Downstream genes of Sox8 that would affect adult male fertility

Sexual Development

Volumn 3, Issue 1, 2009, Pages 16-25

  Singh, A P ^a   Harada, S ^b   Mishina, Yuji ^a,c  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Blood testis barrier; Male fertility; Sertoli cell; Spermatogenesis; Sry box

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR SOX8;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD TESTIS BARRIER; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HETEROZYGOSITY; HOMOZYGOSITY; MALE; MALE FERTILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SERTOLI CELL; SPERMATOGENESIS; TESTIS DEVELOPMENT;

ANIMALS; BLOOD-TESTIS BARRIER; EMBRYO, MAMMALIAN; FERTILITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROZYGOTE; HOMOZYGOTE; MALE; MICE; MICE, MUTANT STRAINS; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SERTOLI CELLS; SOXE TRANSCRIPTION FACTORS; SPERMATOGENESIS; TESTIS;

MUS;

EID: 64149131868     PISSN: 16615425     EISSN: 16615433     Source Type: Journal    
DOI: 10.1159/000200078     Document Type: Article

References (30)

1. Bowles J, Schepers G, Koopman P: Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev Biol 227: 239-255 (2000).
2. Bronstein JM, Chen K, Tiwari-Woodruff S, Kornblum HI: Developmental expression of OSP/claudin-11. J Neurosci Res 60: 284-290 (2000).
3. Chaboissier MC, Kobayashi A, Vidal VI, Lutzkendorf S, van de Kant HJ, et al: Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development 131: 1891-1901 (2004).
4. Clermont Y: Kinetics of spermatogenesis in mammals: seminiferous epithelium cycle and spermatogonial renewal. Physiol Rev 52: 198-236 (1972).
5. Giese K, Pagel J, Grosschedl R: Distinct DNA binding properties of the high mobility group domain of murine and human SRY sex-determining factors. Proc Natl Acad Sci USA 91: 3368-3372 (1994).
6. Goodenough DA: Plugging the leaks. Proc Natl Acad Sci USA 96: 319-321 (1999).
7. Gow A, Southwood CM, Li JS, Pariali M, Riordan GP, et al: CNS myelin and Sertoli cell tight junction strands are absent in Osp/claudin-11 null mice. Cell 99: 649-659 (1999).
8. Kennedy CL, Koopman P, Mishina Y, O'Bryan MK: Sox8 and Sertoli-cell function. Ann N Y Acad Sci 1120: 104-113 (2007).
9. Koopman P: Sex determination: a tale of two Sox genes. Trends Genet 21: 367-370 (2005).
10. Kramer JM, Erickson RP: Developmental program of PGK-1 and PGK-2 isozymes in spermatogenic cells of the mouse: specific activities and rates of synthesis. Dev Biol 87: 37-45 (1981).
11. Levallet G, Levallet J, Bouraima-Lelong H, Bonnamy PJ: Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormonestimulated PDE4 activities in immature rat Sertoli cells. Biol Reprod 76: 794-803 (2007).
12. Lui WY, Cheng CY: Regulation of cell junction dynamics by cytokines in the testis: a molecular and biochemical perspective. Cytokine Growth Factor Rev 18: 299-311 (2007).
13. Lui WY, Mruk DD, Lee WM, Cheng CY: Adherens junction dynamics in the testis and spermatogenesis. J Androl 24: 1-14 (2003).
14. McClive PJ, Hurley TM, Sarraj MA, van den Bergen JA, Sinclair AH: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. Genesis 37: 84-90 (2003).
15. Meng J, Holdcraft RW, Shima JE, Griswold MD, Braun RE: Androgens regulate the permeability of the blood-testis barrier. Proc Natl Acad Sci USA 102: 16696-16700 (2005).
16. O'Bryan MK, Takada S, Kennedy CL, Scott G, Harada S, et al: Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Dev Biol 316: 359-370 (2008).
17. Petersen C, Soder O: The Sertoli cell - a hormonal target and 'super' nurse for germ cells that determines testicular size. Horm Res 66: 153-161 (2006).
18. Pontiggia A, Rimini R, Harley VR, Goodfellow PN, Lovell-Badge R, Bianchi ME: Sex-reversing mutations affect the architecture of SRYDNA complexes. EMBO J 13: 6115-6124 (1994).
19. Salanova M, Chun SY, Iona S, Puri C, Stefanini M, Conti M: Type 4 cyclic adenosine monophosphate- specific phosphodiesterases are expressed in discrete subcellular compartments during rat spermiogenesis. Endocrinology 140: 2297-2306 (1999).
20. Sathananthan AH: Functional competence of abnormal spermatozoa. Baillieres Clin Obstet Gynaecol 8: 141-156 (1994).
21. Schepers GE, Teasdale RD, Koopman P: Twenty pairs of Sox: extent, homology, and nomenclature of the mouse and human Sox transcription factor gene families. Dev Cell 3: 167-170 (2002).
22. Schepers G, Wilson M, Wilhelm D, Koopman P: SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro. J Biol Chem 278: 28101-28108 (2003).
23. Schmidt K, Schinke T, Haberland M, Priemel M, Schilling AF, et al: The high mobility group transcription factor Sox8 is a negative regulator of osteoblast differentiation. J Cell Biol 168: 899-910 (2005).
24. Sharpe RM, McKinnell C, Kivlin C, Fisher JS: Proliferation and functional maturation of Sertoli cells and their relevance to disorders of testis function in adulthood. Reproduction 125: 769-784 (2003).
25. Skakkebaek NE, Rajpert-De Meyts E, Main KM: Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod 16: 972-978 (2001).
26. Skinner MK, Griswold MD: Sertoli cells synthesize and secrete transferrin-like protein. J Biol Chem 255: 9523-9525 (1980).
27. Sock E, Schmidt K, Hermanns-Borgmeyer I, Bosl MR, Wegner M: Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8. Mol Cell Biol 21: 6951-6959 (2001).
28. Tsukita S, Furuse M: The structure and function of claudins, cell adhesion molecules at tight junctions. Ann N Y Acad Sci 915: 129-135 (2000).
29. Van Itallie CM, Anderson JM: The role of claudins in determining paracellular charge selectivity. Proc Am Thorac Soc 1: 38-41 (2004).
30. Walker WH: Molecular mechanisms controlling Sertoli cell proliferation and differentiation. Endocrinology 144: 3719-3721 (2003).