Mutational analysis and allosteric effects in the HIV-1 capsid protein carboxyl-terminal dimerization domain

Biomacromolecules

Volumn 10, Issue 2, 2009, Pages 390-399

  Yu, Xiang ^a   Wang, Qiuming ^a   Yang, Jui Chen ^a   Buch, Idit ^b   Tsai, Chung Jung ^c   Buyong, Ma ^c   Cheng, Stephen Z D ^a   Nussinov, Ruth ^b,c   Zheng, Jie ^b,c  

^a University of Akron   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

^c SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC EFFECTS; CAPSID PROTEINS; CARBOXYL TERMINALS; CARBOXYL-TERMINAL DOMAINS; CONFORMATIONAL DYNAMICS; DIMERIZATION DOMAINS; DRIVING FORCES; HUMAN IMMUNODEFICIENCY VIRUS TYPE-1; HYDROPHOBIC CONTACTS; HYDROPHOBIC INTERACTIONS; LOCAL STRUCTURES; MUTATIONAL ANALYSIS; NATIVE CONFORMATIONS; SIDE CHAINS; STRUCTURAL CHANGES; STRUCTURAL STABILITIES; VIRAL CAPSIDS; VIRAL REPLICATIONS; WILD TYPES;

ANIMAL CELL CULTURE; ASSOCIATION REACTIONS; BINDING SITES; DIMERIZATION; DYNAMICS; ELECTRIC CONDUCTIVITY MEASUREMENT; HYDROGEN; HYDROPHOBICITY; MOLECULAR DYNAMICS; OLIGOMERS; STABILITY; STRUCTURAL ANALYSIS;

HYDROGEN BONDS;

ALANINE; ASPARAGINE; ASPARTIC ACID; CAPSID PROTEIN; DIMER; GLUTAMIC ACID; GLUTAMINE; TRYPTOPHAN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN STABILITY; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; CHEMISTRY; GENETICS; HYDROGEN BOND; PROTEIN MULTIMERIZATION; SITE DIRECTED MUTAGENESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE;

CAPSID PROTEINS; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HYDROGEN BONDING; HYDROPHOBICITY; MUTAGENESIS, SITE-DIRECTED; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION;

EID: 64149109477     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm801151r     Document Type: Article

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