Estradiol and lithium chloride specifically alter NMDA receptor subunit NR1 mRNA and excitotoxicity in primary cultures

Brain Research

Volumn 1268, Issue , 2009, Pages 1-12

  Valdés, James J ^a   Weeks, Ophelia I ^a  

^a FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Estradiol; Excitotoxicity; Glia; Lithium Chloride; NMDA Receptor

Indexed keywords

ESTRADIOL; FLUORESCEIN DIACETATE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; LITHIUM CHLORIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PROPIDIUM IODIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL CULTURE; CELL TYPE; CONTROLLED STUDY; EXCITOTOXICITY; GEL ELECTROPHORESIS; GENE EXPRESSION; GLIA; HIPPOCAMPUS; LEARNING; MEMORY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; ESTRADIOL; EXCITATORY AMINO ACID AGONISTS; GENE EXPRESSION; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; HIPPOCAMPUS; LITHIUM CHLORIDE; MICE; MICE, INBRED C57BL; NEUROFILAMENT PROTEINS; NEUROGLIA; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER;

MUS;

EID: 64149094323     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.02.066     Document Type: Article

References (59)

1. Adams M.M., Oung T., Morrison J.H., and Gore A.C. Length of postovariectomy interval and age, but not estrogen replacement, regulate N-methyl-d-aspartate receptor mRNA levels in the hippocampus of female rats. Exp. Neurol. 170 (2001) 345-356
2. Angelucci F., Aloe L., Jiménez-Vasquez P., and Mathé A.A. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression. Int. J. Neuropsychopharmacol. 6 (2003) 225-231
3. Brewer G.J. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus. J. Neurosci. Res. 42 (1995) 674-683
4. Burt V.K., and Rasgon N. Special considerations in treating bipolar disorder in women. Bipolar Disord. 6 (2004) 2-13
5. Cabrera R.J., Bregonzio C., Laconi M., and Mampel A. Allopregnanolone increase in striatal N-methyl-d-aspartic acid evoked [3H]dopamine release is estrogen and progesterone dependent. Cell. Mol. Neurobiol. 22 (2002) 445-454
6. Campbell A.K., and Siddle K. Effect of replacement of extracellular sodium ions and of D-600 on the activation by adrenalin of adenylate cyclase in intact pigeon erythrocytes. Mol. Cell. Endocrinol. 11 (1978) 79-89
7. Cardona-Gomez P., Perez M., Avila J., Garcia-Segura L.M., and Wandosell F. Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus. Mol. Cell. Neurosci. 25 (2004) 363-373
8. Chen P., Gu Z., Liu W., and Yan Z. Glycogen synthase kinase 3 regulates N-methyl-d-aspartate receptor channel trafficking and function in cortical neurons. Mol. Pharmacol. 72 (2007) 40-51
9. Chen S., Nilsen J., and Brinton R.D. Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons. Ther. Implications. 147 (2006) 5303-5313
10. Chuang D.-M., Chen R.-W., Chalecka-Franaszek E., Ren M., Hashimoto R., Senatorov V., Kanai H., Hough C., Hiroi T., and Leeds P. Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar Disord. 4 (2002) 129-136
11. Conti F., DeBiasi S., Minelli A., and Melone M. Expression of NR1 and NR2A/B subunits of the NMDA receptor in cortical astrocytes. Glia. 17 (1996) 254-258
12. Conti F., Barbaresi P., Melone M., and Ducati A. Neuronal and glial localization of NR1 and NR2A/B subunits of the NMDA receptor in the human cerebral cortex. Cereb. Cortex 9 (1999) 110-120
13. Dominguez R., Liu R., and Baudry M. 17b-Estradiol-mediated activation of extracellular-signal regulated kinase, phosphatidylinositol 3-kinase/protein kinase B-Akt and N-methyl-d-aspartate receptor phosphorylation in cortical synaptoneurosomes. J. Neurochem. 101 (2007) 232-240
14. Garcia-Segura L.M., Azcoitia I., and DonCarlos L.L. Neuroprotection by estradiol. Prog. Neurobiol. 63 (2001) 29-60
15. Goodenough S., Schafer M., and Behl C. Estrogen-induced cell signalling in a cellular model of Alzheimer's disease. J. Steroid Biochem. Mol. Biol. 84 (2003) 301-305
16. Goodenough S., Schleusner D., Pietrzik C., Skutella T., and Behl C. Glycogen synthase kinase 3b links neuroprotection by 17b-estradiol to key Alzheimer processes. Neuroscience 132 (2005) 581-589
17. Grimes C.A., and Jope R.S. CREB DNA binding activity is inhibited by glycogen synthase kinase-3b and facilitated by lithium. J. Neurochem. 78 (2001) 1219-1232
18. Hashimoto R., Hough C., Nakazawa T., Yamamoto T., and Chuang D.-M. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J. Neurochem. 80 (2002) 589-597
19. Hashimoto R., Fujimaki K., Jeong M.R., Christ L., and Chuang D.-M. Lithium-induced inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N-methyl-d-aspartate receptor-mediated excitotoxicity. FEBS Lett. 538 (2003) 145-148
20. Henderson, V.W., Paganini-Hill, A., Emanuel, C.K., Dunn, M.E., Buckwalter, J.G., 1994. Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects. Arch Neurol. 51, 896-900.
21. Honda K., Shimohama S., Sawada H., Kihara T., Nakamizo T., Shibasaki H., and Akaike A. Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons. J. Neurosci. Res.. 64 (2001) 466-475
22. Hongisto V., Smeds N., Brecht S., Herdegen T., Courtney M.J., and Coffey E.T. Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. Mol. Cell. Biol. 23 (2003) 6027-6036
23. Hu R., Cai W.Q., Wu X.G., and Yang Z. Astrocyte-derived estrogen enhances synapse formation and synaptic transmission between cultured neonatal rat cortical neurons. Neuroscience. 144 (2007) 1229-1240
24. Jelks K.B., Wylie R., Floyd C.L., McAllister A.K., and Wise P. Estradiol targets synaptic proteins to induce glutamatergic synapse formation in cultured hippocampal neurons: critical role of estrogen receptor-a. J. Neurosci. 27 (2007) 6903-6913
25. Jones, K.H., Senft, J.A., 1985. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. J. Histochem. Cytochem. 33, 77-79.
26. Jope R.S. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol. Sci. 24 (2003) 441-443
27. Kabakov A.Y., Karkanias N.B., Lenox R.H., and Papke R.L. Synapse-specific accumulation of lithium in intracellular microdomains: a model for uncoupling coincidence detection in the brain. Synapse 28 (1998) 271-279
28. Klein, P.S., Melton, D.A., 1996. A molecular mechanism for the effect of lithium on development. PNAS. 93, 8455-8459.
29. Kukopulos A., Minnai G., and Muller-Oerlinghausen B. The influence of mania and depression on the pharmacokinetics of lithium: a longitudinal single-case study. J. Affect. Disord. 8 (1985) 159-166
30. Lalo, U., Pankratov, Y., Kirchhoff, F., North, R.A., Verkhratsky, A., 2006. NMDA Receptors Mediate Neuron-to-Glia Signaling in Mouse Cortical Astrocytes. J. Neurosci. 26, 2673-2683.
31. Leranth C., Shanabrough M., and Redmond D.E. Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates. J. Comparative Neurol. 447 (2002) 34-42
32. Lewis D.K., Johnson A.B., Stohlgren S., Harms A., and Sohrabji F. Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats. J. Neuroimmunol. 195 (2008) 47-59
33. Lipton S.A. The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism. Curr. Alzheimer Res. 2 (2005) 155-165
34. Ma J., Zhang G.-Y., Liu Y., Yan J.-Z., and Hao Z.-B. Lithium suppressed Tyr-402 phosphorylation of proline-rich tyrosine kinase (Pyk2) and interactions of Pyk2 and PSD-95 with NR2A in rat hippocampus following cerebral ischemia. Neurosci. Res. 49 (2004) 357-362
35. Matute C., Alberdi E., Ibarretxe G., and Sánchez-Gómez M.V. Excitotoxicity in glial cells. Eur. J. Pharmacol. 447 (2002) 239-246
36. McEwen B.S. Genome and hormones: gender differences in physiology: invited review: estrogens effects on the brain: multiple sites and molecular mechanisms. J. Appl. Physiol. 91 (2001) 2785-2801
37. Medunjanin S., Hermani A., De Servi B., Grisouard J., Rincke G., and Mayer D. Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor a and is involved in the regulation of receptor activity. J. Biol. Chem. 280 (2005) 33006-33014
38. Mishizen-Eberz A.J., Rissman R.A., Carter T.L., Ikonomovic M.D., Wolfe B.B., and Armstrong D.M. Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology. Neurobiol. Dis. 15 (2004) 80-92
39. Morissette M., and Di Paolo T. Acute effect of 17[beta]-estradiol and lithium on ovariectomized rat brain biogenic amines metabolism. J. Psychiatr. Res. 30 (1996) 95
40. Morissette M., Le Saux M., D'Astous M., Jourdain S., Al Sweidi S., Morin N., Estrada-Camarena E., Mendez P., Garcia-Segura L.M., and Di Paolo T. Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain. J. Steroid Biochem. Mol. Biol. 108 (2008) 327-338
41. Mugnaini M., van Amsterdam F., Ratti E., Trist D., and Bowery N. Regionally different N-methyl-d-aspartate receptors distinguished by ligand binding and quantitative autoradiography of [3H]-CGP 39653 in rat brain. Br. J. Pharmacol. 119 (1996) 819-828
42. Newcomer L.M., Newcomb P.A., Potter J.D., Yasui Y., Trentham-Dietz A., Storer B.E., Longnecker M.P., Baron J.A., and Daling J.R. Postmenopausal hormone therapy and risk of breast cancer by histologic type United States. Cancer Causes Control 14 (2003) 225-233
43. Newman M.E., and Belmaker R.H. Effects of lithium in vitro and ex vivo on components of the adenylate cyclase system in membranes from the cerebral cortex of the rat. Neuropharmacology 26 (1987) 211-217
44. Nonaka S., Hough C.J., and Chuang D.-M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-d-aspartate receptor-mediated calcium influx. PNAS 95 (1998) 2642-2647
45. Ozaki N., and Chuang D.-M. Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. J. Neurochem. 69 (1997) 2336-2344
46. Peineau S., Taghibiglou C., Bradley C., Wong T.P., Liu L., Lu J., Lo E., Wu D., Saule E., Bouschet T., Matthews P., Isaac J.T.R., Bortolotto Z.A., Wang Y.T., and Collingridge G.L. LTP inhibits LTD in the hippocampus via regulation of GSK3b. Neuron 53 (2007) 703-717
47. Perrella J., and Bhavnani B. Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism. BMC Neurosci. 6 (2005) 34-51
48. Qiang M., and Ticku M.K. Role of AP-1 in ethanol-induced N-methyl-d-aspartate receptor 2B subunit gene up-regulation in mouse cortical neurons. J. Neurochem. 95 (2005) 1332-1341
49. Rasband W.S. Image J (1997-2007), U. S. National Institutes of Health, Bethesda
50. Rocha E., and Rodnight R. Chronic administration of lithium chloride increases immunodetectable glial fibrillary acidic protein in the rat hippocampus. J. Neurochem. 63 (1994) 1582-1584
51. Rowe M.K., and Chuang D. Lithium neuroprotection: molecular mechanisms and clinical implications. Exp. Rev. Mol. Med. 6 (2004) 1-18
52. Ryves W.J., and Harwood A.J. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280 (2001) 720-725
53. Sasson S., and Notides A.C. Estriol and estrone interaction with the estrogen receptor: temperature-induced modulation of the cooperative binding of [3H] estriol and [3H] estrone to the estrogen receptor. J. Biol. Chem. 258 (1983) 8113-8117
54. Silverstone T. Dopamine in manic depressive illness : a pharmacological synthesis. J. Affect. Dis. 8 (1985) 225-231
55. Solum D.T., and Handa R.J. Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus. J. Neurosci. 22 (2002) 2650-2659
56. Stephenson F.A. Subunit characterization of NMDA receptors. Curr. Drug Targets 2 (2001) 233-239
57. Van Eldik L.J., Thompson W.L., Ranaivo H.R., Behanna H.A., and Martin Watterson D. Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: function-based and target-based discovery approaches. Int. Rev. Neurobiol. 82 (2007) 277-296
58. Watanabe T., Inoue S., Hiroi H., Orimo A., and Muramatsu M. NMDA receptor type 2D gene as target for estrogen receptor in the brain. Molec. Brain Res. 63 (1999) 375-379
59. Wu T.W., Wang J.M., Chen S., and Brinton R.D. 17b-estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection. Neuroscience 135 (2005) 59-72