Presence of a novel Ehrlichia sp. in Ixodes granulatus found in Okinawa, Japan

Microbiology and Immunology

Volumn 53, Issue 2, 2009, Pages 101-106

  Takano, Ai ^a,b   Ando, Shuji ^a   Kishimoto, Toshio ^a   Fujita, Hiromi ^c   Kadosaka, Teruki ^d   Nitta, Yoshiki ^e   Kawabata, Hiroki ^a,b   Watanabe, Haruo ^a,b  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c National Hospital Organization   (Japan)

^d AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e Okinawa Prefectural Institute of Animal Health   (Japan)

Author keywords

Ehrlichia; Ixodes granulatus; Wild small mammals

Indexed keywords

BACTERIAL DNA; RNA 16S;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; DNA SEQUENCE; EHRLICHIA; EHRLICHIA 360; EHRLICHIA CHAFFEENSIS; EHRLICHIA MURIS; GROEL GENE; IXODES; IXODES GRANULATUS; IXODES OVATUS; JAPAN; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OMP 1 GENE; SEQUENCE ANALYSIS; SMALL MAMMAL; ANIMAL; CLASSIFICATION; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; PHYLOGENY;

EHRLICHIA; EHRLICHIA CHAFFEENSIS; EHRLICHIA MURIS; EHRLICHIA SP.; IXODES GRANULATUS; IXODIDA; MAMMALIA;

ANIMALS; DNA, BACTERIAL; EHRLICHIA; IXODES; JAPAN; PHYLOGENY; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA;

EID: 64049112063     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2008.00093.x     Document Type: Article

References (31)

1. Rikihisa Y. (1999) Clinical and biological aspects of infection caused by Ehrlichia chaffeensis. Microbes Infect 5: 367-76.
2. Stone J.H., Dierberg K., Aram G., Dumler J.S. (2004) Human monocytic ehrlichiosis. J AmMed Assoc 292: 2263-70.
3. Dumler J.S., Madigan J.E., Pusterla N., Bakken J.S. (2007) Ehrlichioses in humans: epidemiology, clinical presentation, diagnosis, and treatment. Clin Infect Dis 15: S45-51.
4. Buller R.S., Arens M., Hmiel S.P., Paddock C.D., Sumner J.W., Rikhisa Y., Unver A., Gaudreault-Keener M., Manian F.A., Liddell A.M., Schmulewitz N., Storch G.A. (1999) Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis. N Engl J Med 341: 148-55.
5. Bool P. H., Sutmoller P. (1957) Ehrlichia canis infections in dogs on Aruba (Netherlands Antilles). J AmVetMed Assoc 130: 418-20.
6. Wen B., Rikihisa Y., Mott J., Fuerst P.A., Kawahara M., Suto C. (1995) Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics. Int J Syst Bacteriol 45: 250-4.
7. Du Plessis J.L. (1970) Pathogenesis of heartwater. I. Cowdria ruminantium in the lymph nodes of domestic ruminants. Onderstepoort J Vet Res 37: 89-95.
8. Dumler J.S., Barbet A.F., Bekker C.P., Dasch G.A., Palmer G.H., Ray S.C., Rikihisa Y., Rurangirwa F.R. (2001) Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila. Int J Syst Evol Microbiol 51: 2145-65.
9. Inokuma H., Ohashi M., Jilintai, Tanabe S., Miyahara K. (2007) Prevalence of tick-borne Rickettsia and Ehrlichia in Ixodes persulcatus and Ixodes ovatus in Tokachi district, Eastern Hokkaido, Japan. J VetMed Sci 69: 661-4.
10. Faburay B., Geysen D., Munstermann S., Taoufik A., Postigo M., Jongejan F. (2007) Molecular detection of Ehrlichia ruminantium infection in Amblyomma variegatum ticks in The Gambia. Exp Appl Acarol 42: 61-74.
11. Kiel J.L., Alarcon R.M., Parker J.E., Vivekananda J., Gonzalez Y.B., Stribling L.J., Andrews C.J. (2006) Emerging tick-borne disease in African vipers caused by a Cowdria-like organism. Ann N Y Acad Sci 1081: 434-42.
12. Kawahara M., Ito T., Suto C., Shibata S., Rikihisa Y., Hata K., Hirai K. (1999) Comparison of Ehrlichia muris strains isolated from wild mice and ticks and serologic survey of humans and animals with E. muris as antigen. J ClinMicrobiol 37: 1123-9.
13. Fujita H., Watanabe Y. (1994) Ehrlichial organisms isolated from Ixodes ovatus ticks and field rodents in Japan. Ann Rep Ohara Hosp 37: 13-17.
14. Shibata S., Kawahara M., Rikihisa Y., Fujita H., Watanabe Y., Suto C., Ito T. (2000) New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan. J Clin Microbiol 38: 1331-8.
15. Inayoshi M., Naitou H., Kawamori F., Masuzawa T., Ohashi N. (2004) Characterization of Ehrlichia species from Ixodes ovatus ticks at the foot of Mt. Fuji, Japan. Microbiol Immunol 48: 737-45.
16. Inokuma H., Ohno K., Onishi T., Raoult D., Brouqui P. (2001) Detection of ehrlichial infection by PCR in dogs from Yamaguchi and Okinawa Prefectures, Japan. J VetMed Sci 63: 815-7.
17. Naitou H., Kawaguchi D., Nishimura Y., Inayoshi M., Kawamori F., Masuzawa T., Hiroi M., Kurashige H., Kawabata H., Fujita H., Ohashi N. (2006) Molecular identification of Ehrlichia species and 'Candidatus Neoehrlichia mikurensis' from ticks and wild rodents in Shizuoka and Nagano Prefectures, Japan. Microbiol Immunol 50: 45-51.
18. Kawahara M., Rikihisa Y., Isogai E., Takahashi M., Misumi H., Suto C., Shibata S., Zhang C., Tsuji M. (2004) Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks. Int J Syst Evol Microbiol 54: 1837-43.
19. Masuzawa T., Hashimoto N., Kudeken M., Kadosaka T., Nakamura M., Kawabata H., Koizumi N., Imai Y. (2004) New genomospecies related to Borrelia valaisiana, isolated from mammals in Okinawa archipelago, Japan. J MedMicrobiol 53: 421-6.
20. Kollars T.M. Jr., Tippayachai B., Bodhidatta D. (2001) Short report: Thai tick typhus, Rickettsia honei, and a unique rickettsia detected in Ixodes granulatus (Ixodidae: Acari) from Thailand. Am J Trop Med Hyg 65: 535-7.
21. Takada N. (1990) Pictorial Review of Medical Acarology in Japan. Kyoto: Kinpodo, pp. 136-9.
22. Tabara K., Arai S., Kawabuchi T., Itagaki A., Ishihara C., Satoh H., Okabe N., Tsuji M. (2007) Molecular survey of Babesia microti, Ehrlichia species and Candidatus Neoehrlichia mikurensis in wild rodents from Shimane Prefecture, Japan. Microbiol Immunol 51: 359-67.
23. Kawabata H., Ando S., Kishimoto T., Kurane I., Takano A., Nogami S., Fujita H., Tsurumi M., Nakamura N., Sato F., Takahashi M., Ushijima Y., Fukunaga M.,Watanabe H. (2006) First detection of Rickettsia in soft-bodied ticks associated with seabird, Japan. Microbiol Immunol 50: 403-6.
24. Tamura K., Dudley J., Nei M., Kumar S. (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24: 1596-9.
25. Inokuma H., Beppu T., Okuda M., Shimada Y., Sakata Y. (2004) Detection of ehrlichial DNA in Haemaphysalis ticks recovered from dogs in Japan that is closely related to a novel Ehrlichia sp. found in cattle ticks from Tibet, Thailand, and Africa. J ClinMicrobiol 42: 1353-5.
26. Kawahara M., Rikihisa Y., Lin Q., Isogai E., Tahara K., Itagaki A., Hiramitsu Y., Tajima T. (2006) Novel genetic variants of Anaplasma phagocytophilum, Anaplasma bovis, Anaplasma centrale, and a novel Ehrlichia sp. in wild deer and ticks on two major islands in Japan. Appl Environ Microbiol 72: 1102-9.
27. Teglas M.B., Foley J. (2006) Differences in the transmissibility of two Anaplasma phagocytophilum strains by the North American tick vector species, Ixodes pacificus and Ixodes scapularis (Acari: Ixodidae). Exp Appl Acarol 38: 47-58.
28. Bjöersdorff A., Bergström S., Massung R.F., Haemig P.D., Olsen B. (2001) Ehrlichia-infected ticks on migrating birds. Emerg Infect Dis 7: 877-9.
29. Winslow G.M., Yager E., Shilo K., Collins D.N., Chu F.K. (1998) Infection of the Laboratory Mouse with the Intracellular Pathogen Ehrlichia chaffeensis. Infect Immun 66: 3892-9.
30. Saito K., Ito T., Asashima N., Ohno M., Nagai R., Fujita H., Koizumi N., Takano A.,Watanabe H., Kawabata, H. (2007) Case report: Borrelia valaisiana infection in a Japanese man associated with traveling to foreign countries. Am J Trop Med Hyg 77: 1124-7.
31. Jiang J., Sangkasuwan V., Lerdthusnee K., Sukwit S., Chuenchitra T., Rozmajzl P.J., Eamsila C., Jones J.W., Richards A.L. (2005) Human Infection with Rickettsia honei, Thailand. Emerg Infect Dis 11: 1473-5.