Characterization of Ehrlichia species from Ixodes ovatus ticks at the foot of Mt. Fuji, Japan

Microbiology and Immunology

Volumn 48, Issue 10, 2004, Pages 737-745

  Inayoshi, Megumi ^a,b   Naitou, Hirotaka ^a   Kawamori, Fumihiko ^a,b   Masuzawa, Toshiyuki ^a   Ohashi, Norio ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b SHIZUOKA INSTITUTE OF ENVIRONMENT AND HYGIENE   (Japan)

Author keywords

16S rDNA; Ehrlichia; Ixodes ovatus; Omp 1 Multigene family

Indexed keywords

DNA 16S;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA DETERMINATION; EHRLICHIA; EHRLICHIA CHAFFEENSIS; EHRLICHIOSIS; EXPERIMENTAL ANIMAL; IXODES; IXODES OVATUS; IXODES PERSULCATUS; JAPAN; MALE; MOUSE; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; OMP 1 GENE; PATHOGENESIS; PREVALENCE; SPLEEN; STRAIN DIFFERENCE; TICK; UNINDEXED SEQUENCE;

ACARI; ANAPLASMATACEAE; ANIMALIA; BACTERIA (MICROORGANISMS); EHRLICHIA; EHRLICHIA CHAFFEENSIS; IXODES; IXODES OVATUS; IXODES PERSULCATUS; OVATUS; RICKETTSIALES;

EID: 7244250432     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2004.tb03599.x     Document Type: Article

References (33)

1. Anderson, B.E., Dawson, J.E., Jones, D.C., and Wilson, K.H. 1991. Ehrlichia chaffeensis, a new species associated with human ehrlichiosis. J. Clin. Microbiol. 29: 2838-2842.
2. Anderson, B.E., Sims, K.G., Olson, J.G., Childs, J.M., Piesman, J.F., Happ, C.M., Maupin, G.O., and Johnson, B.J.B. 1993. Amblyomma americanum: a potential vector of human ehrlichiosis. Am. J. Trop. Med. Hyg. 49: 239-244.
3. Buller, R.S., Arens, M., Hmiel, S.P., Paddock, C.D., Sumner, J.W., Rikihisa, Y., Unver, A., Gaudreault-Keener, M., Manian, F.A., Liddell, A.M., Schmulewitz, N., and Storch, G.A. 1999. Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis. New Engl. J. Med. 341: 148-155.
4. Cao, W.-C., Zhao, Q.-M., Zhang, P.-H., Dumler, J.S., Zhang, X.-T., Fang, L.-Q., and Yang, H. 2000. Granulocytic ehrlichiae in Ixodes persulcatus ticks from an area in China where lyme disease is endemic. J. Clin. Microbiol. 38: 4208-4210.
5. Dumler, J.S., Barbet, A.F., Bekker, C.P., Dasch, G.A., Palmer, G.H., Ray, S.C., Rikihisa, Y., and Rurangirwa, F.R. 2001. Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila. Int. J. Syst. Evol. Microbiol. 51: 2145-2165.
6. Fournier, P.-E., Fujita, H., Takada, N., and Raoult, D. 2002. Genetic identification of rickettsiae isolated from ticks in Japan. J. Clin. Microbiol. 40: 2176-2181.
7. Fujita, H., and Watanabe, Y. 1994. Ehrlichial organisms isolated from Ixodes ovatus ticks and field rodents in Japan. Ann. Rep. Ohara Hosp. 37: 13-17 (in Japanese).
8. Guerrero, A., Fishbein, D.B., Mesa, E., and Escudero, R. 1991. Human infection by Ehrlichia canis in Spain. Med. Clin. 96: 236-237.
9. Inokuma, H., Parola, P., Raoult, D., and Brouqui, P. 2001. Molecular survey of Ehrlichia infection in ticks from animals in Yamaguchi Prefecture, Japan. Vet. Parasitol. 99: 335-339.
10. Hardalo, C.J., Quangliarello, V., and Dumler, J.S. 1995. Human granulocytic ehrlichiosis in Connecticut: report of a fatal case. Clin. Infect. Dis. 21: 910-914.
11. Kawahara, M., Rikihisa, Y., Isogai, E., Takahashi, M., Misumi, H., Suto, C., Shibata, S., Zhang, C., and Tsuji, M. 2004. Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae isolated from wild rats and found in Ixodes ovatus ticks. Int. J. Syst. Evol. Microbiol. 54: 1837-1843.
12. Kawahara, M., Suto, C., Rikihisa, Y., Yamamoto, S., and Tsuboi, Y. 1993. Characterization of ehrlichial organisms isolated from a wild mouse. J. Clin. Microbiol. 31: 89-96.
13. Kawahara, M., Ito, T., Suto, C., Shibata, S., Rikihisa, Y., Hata, K., and Hirai, K. 1999. Comparison of Ehrlichia muris strains isolated from wild mice and ticks and serologic survey of humans and animals with E. muris as antigen. J. Clin. Microbiol. 37: 1123-1129.
14. Masuzawa, T., Kawabata, H. Beppu, Y., Miyamoto, K., Nakao, M., Sato, N., Muramatsu, K., Johnson, R.C., and Yanagihara, Y. 1994. Characterization of monoclonal antibodies for identification of Borrelia japonica isolates from Ixodes ovatus. Microbiol. Immunol. 38: 393-398.
15. Morais, J.D., Dawson, J.E., Greene, C., Filipe, A.R., Galhardas, L.C., and Bacellar, F. 1991. First European case of ehrlichiosis. Lancet 388: 633-634.
16. Ohashi, N., Rikihisa, Y., and Unver, A. 2001. Analysis of transcriptionally active gene clusters of major outer membrane protein multigene family in Ehrlichia canis and E. chaffeensis. Infect. Immun. 69: 2083-2091.
17. Ohashi, N., Unver, A., Zhi, N., and Rikihisa, Y. 1998. Cloning and characterization of multigenes encoding the immunodominant 30-kilodalton major outer membrane proteins of Ehrlichia canis and application of the recombinant protein for serodiagnosis. J. Clin. Microbiol. 36: 2671-2680.
18. Ohashi, N., Zhi, N., Zhang, Y., and Rikihisa, Y. 1998. Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family. Infect. Immun. 66: 132-139.
19. Okada, H., Tajima, T., Kawahara, M., and Rikihisa, Y. 2001. Ehrlichial proliferation and acute hepatocellular necrosis in immunocompetent mice experimentally infected with the HF strain of Ehrlichia, closely related to Ehrlichia chaffeensis. J. Comp. Pathol. 124: 165-171.
20. Perez, M., Rikihisa, Y., and Wen, B. 1996. Ehrlichia canis-like agent isolated from a man in Venezuela: antigenic and genetic characterization. J. Clin. Microbiol. 34: 2133-2139.
21. Ravyn, M.D., Korenberg, E.I., Oeding, J.A., Kovalevskii, Y.V., and Johnson, R.C. 1999. Monocytic Ehrlichia in Ixodes persulcatus ticks from Perm, Russia. Lancet 353: 722-723.
22. Rikihisa, Y. 1991. The tribe Ehrlichieae and ehrlichial diseases. Clin. Microbiol. Rev. 4: 286-308.
23. Rikihisa, Y. 1999. Clinical and biological aspects of infection caused by Ehrlichia chaffeensis. Microb. Infect. 1: 367-376.
24. Rikihisa, Y., Ewing, S.A., and Fox, J.C. 1994. Western blot analysis of Ehrlichia chaffeensis, E. canis, or E. ewingii infection of dogs and humans. J. Clin. Microbiol. 32: 2107-2112.
25. Rikihisa, Y., Zhi, N., Wormser, G.P., Wen, B., Horowitz, H.W., and Hechemy, K.E. 1997. Ultrastructural and antigenic characterization of a granulocytic ehrlichiosis agent directly isolated and stably cultivated from a patient in New York State. J. Infect. Dis. 175: 210-213.
26. Saitou, N., and Nei, M. 1987. The neighbor-joining method: a new method for reconstructing phylogenetic tree. Mol. Biol. Evol. 4: 406-425.
27. Shibata, S., Kawahara, M., Rikihisa, Y., Fujita, H., Watanabe, Y., Suto, C., and Ito, T. 2000. New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan. J. Clin. Microbiol. 38: 1331-1338.
28. Tachibana, N., and Kobayashi, Y. 1975. Effect of cyclophosphamide on the growth of Rickettsia sennetsu in experimentally infected mice. Infect. Immun. 12: 625-629.
29. Thompson, J.D., Gibson, T.J., Plewniak, F., Jeanmougin, F., and Higgins, D.G. 1997. The CLUSTAL X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25: 4876-4882.
30. Uhaa, I.J., MacLean, J.D., Greene, C.R., and Fishbein, D.B. 1992. A case of human ehrlichiosis acquired in Mali: clinical and laboratory findings. Am. J. Trop. Med. Hyg. 46: 161-164.
31. Wen, B., Rikihisa, Y., Mott, J., Fuerst, P.A., Kawahara, M., and Suto, C. 1995. Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics. Int. J. Sys. Bacteriol. 45: 250-254.
32. Yamaguchi, N., and Kitaoka, S. 1980. Ixodes ovatus Neumann, p. 149-155. In Ehara, S. (ed), Illustrations of the mites and ticks of Japan. Zenkoku Noson Kyoiku Kyokai, Tokyo, Japan (in Japanese).
33. Zhi, N., Ohashi, N., and Rikihisa, Y. 1999. Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent. J. Biol. Chem. 274: 17828-17836.