메뉴 건너뛰기




Volumn 14, Issue 9, 2008, Pages 1150-1168

Bisphosphonate-associated osteomyelitis of the jaw: Guidelines for practicing clinicians

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; ALENDRONIC ACID PLUS COLECALCIFEROL; AMOXICILLIN; BISPHOSPHONIC ACID DERIVATIVE; CHLORHEXIDINE GLUCONATE; CLODRONIC ACID; CORTICOSTEROID; ETIDRONIC ACID; IBANDRONIC ACID; INCADRONIC ACID; MOUTHWASH; PAMIDRONIC ACID; PENICILLIN V; RISEDRONIC ACID; TILUDRONIC ACID; ZOLEDRONIC ACID; ANGIOGENESIS INHIBITOR; BONE DENSITY CONSERVATION AGENT;

EID: 64049103096     PISSN: 1530891X     EISSN: None     Source Type: Journal    
DOI: 10.4158/EP.14.9.1150     Document Type: Review
Times cited : (13)

References (160)
  • 2
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy
    • Russell RG, Watts NB, Ebetino FH, Rogers MJ. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int. 2008;19:733-759.
    • (2008) Osteoporos Int , vol.19 , pp. 733-759
    • Russell, R.G.1    Watts, N.B.2    Ebetino, F.H.3    Rogers, M.J.4
  • 4
    • 29144436466 scopus 로고    scopus 로고
    • Migliorati CA, Casiglia J, Epstein J, Jacobsen PL, Siegel MA, Woo SB. Managing the care of patients with bisphosphonate-associated osteonecrosis: an American Academy of Oral Medicine position paper [published correction appears in J Am Dent Assoc. 2006;137:26]. J Am Dent Assoc. 2005;136:1658-1668.
    • Migliorati CA, Casiglia J, Epstein J, Jacobsen PL, Siegel MA, Woo SB. Managing the care of patients with bisphosphonate-associated osteonecrosis: an American Academy of Oral Medicine position paper [published correction appears in J Am Dent Assoc. 2006;137:26]. J Am Dent Assoc. 2005;136:1658-1668.
  • 5
    • 33746884732 scopus 로고    scopus 로고
    • eds, St. Louis, MO: Wolters Kluwer Health, Inc
    • Wickersham RM, Novak KK, eds. Drug Facts and Comparisons. St. Louis, MO: Wolters Kluwer Health, Inc., 2006.
    • (2006) Drug Facts and Comparisons
  • 6
    • 36549072502 scopus 로고    scopus 로고
    • Bisphosphonates: An update on mechanisms of action and how these relate to clinical efficacy
    • Russell RG, Xia Z, Dunford JE, et al. Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. Ann N Y Acad Sci. 2007;1117:209-257.
    • (2007) Ann N Y Acad Sci , vol.1117 , pp. 209-257
    • Russell, R.G.1    Xia, Z.2    Dunford, J.E.3
  • 7
    • 15444369820 scopus 로고    scopus 로고
    • Discovery, clinical development, and therapeutic uses of bisphosphonates
    • Licata AA. Discovery, clinical development, and therapeutic uses of bisphosphonates. Ann Pharmacother. 2005;39:668-677.
    • (2005) Ann Pharmacother , vol.39 , pp. 668-677
    • Licata, A.A.1
  • 8
    • 21044453588 scopus 로고    scopus 로고
    • New therapeutic agents for the treatment of bone diseases
    • Lipton A. New therapeutic agents for the treatment of bone diseases. Expert Opin Biol Ther. 2005;5:817-832.
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 817-832
    • Lipton, A.1
  • 9
    • 77149164099 scopus 로고    scopus 로고
    • National Osteoporosis Foundation 2008 Clinician's Guide to Prevention and Treatment of Osteoporosis and the World Health Organization Fracture Risk Assessment Tool (FRAX): What they mean to the bone densitometrist and bone technologist
    • Watts NB, Lewiecki EM, Miller PD, Baim S. National Osteoporosis Foundation 2008 Clinician's Guide to Prevention and Treatment of Osteoporosis and the World Health Organization Fracture Risk Assessment Tool (FRAX): what they mean to the bone densitometrist and bone technologist. J Clin Densitom. 2008;12:25-31.
    • (2008) J Clin Densitom , vol.12 , pp. 25-31
    • Watts, N.B.1    Lewiecki, E.M.2    Miller, P.D.3    Baim, S.4
  • 10
  • 11
    • 0028488538 scopus 로고
    • Effects of topical administration of a bisphosphonate (risedronate) on orthodontic tooth movements in rats
    • Adachi H, Igarashi K,Mitani H, Shinoda H. Effects of topical administration of a bisphosphonate (risedronate) on orthodontic tooth movements in rats. J Dent Res. 1994;73:1478-1486.
    • (1994) J Dent Res , vol.73 , pp. 1478-1486
    • Adachi, H.1    Igarashi, K.2    Mitani, H.3    Shinoda, H.4
  • 12
    • 16644368865 scopus 로고    scopus 로고
    • Effects of local administration of clodronate on orthodontic tooth movement and root resorption in rats
    • Liu L, Igarashi K, Haruyama N, Saeki S, Shinoda H, Mitani H. Effects of local administration of clodronate on orthodontic tooth movement and root resorption in rats. Eur J Orthod. 2004;26:469-473.
    • (2004) Eur J Orthod , vol.26 , pp. 469-473
    • Liu, L.1    Igarashi, K.2    Haruyama, N.3    Saeki, S.4    Shinoda, H.5    Mitani, H.6
  • 14
    • 27744457043 scopus 로고    scopus 로고
    • Osteoclasts but not osteoblasts are affected by a calcified surface treated with zoledronic acid in vitro
    • Schindeler A, Little DG. Osteoclasts but not osteoblasts are affected by a calcified surface treated with zoledronic acid in vitro. Biochem Biophys Res Commun. 2005;338:710-716.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 710-716
    • Schindeler, A.1    Little, D.G.2
  • 16
    • 0036729485 scopus 로고    scopus 로고
    • (American Society of Clinical Oncology Bisphosphonates Expert Panel). American Society of Clinical Oncology clinical practice guidelines: The role of bisphosphonates in multiple myeloma
    • Berenson JR, Hillner BE, Kyle RA, et al (American Society of Clinical Oncology Bisphosphonates Expert Panel). American Society of Clinical Oncology clinical practice guidelines: the role of bisphosphonates in multiple myeloma. J Clin Oncol. 2002;20:3719-3736.
    • (2002) J Clin Oncol , vol.20 , pp. 3719-3736
    • Berenson, J.R.1    Hillner, B.E.2    Kyle, R.A.3
  • 17
    • 0642342669 scopus 로고    scopus 로고
    • Hillner BE, Ingle JN, Chlebowski RT, et al (American Society of Clinical Oncology). American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer [published correction appears in J Clin Oncol. 2004;22:1351]. J Clin Oncol. 2003;21:4042-4057.
    • Hillner BE, Ingle JN, Chlebowski RT, et al (American Society of Clinical Oncology). American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer [published correction appears in J Clin Oncol. 2004;22:1351]. J Clin Oncol. 2003;21:4042-4057.
  • 18
    • 27344453813 scopus 로고    scopus 로고
    • Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: Risk factors, recognition, prevention, and treatment
    • Marx RE, Sawatari Y, Fortin M, Broumand V. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg. 2005; 63:1567-1575.
    • (2005) J Oral Maxillofac Surg , vol.63 , pp. 1567-1575
    • Marx, R.E.1    Sawatari, Y.2    Fortin, M.3    Broumand, V.4
  • 19
    • 33751258400 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in patients receiving intravenous bisphosphonate therapy
    • Hoff AO, Toth BB, Altundag K, et al. Osteonecrosis of the jaw in patients receiving intravenous bisphosphonate therapy. J Clin Oncol. 2006;24:8528.
    • (2006) J Clin Oncol , vol.24 , pp. 8528
    • Hoff, A.O.1    Toth, B.B.2    Altundag, K.3
  • 20
    • 5444252652 scopus 로고    scopus 로고
    • Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: A new clinical entity
    • Lugassy G, Shaham R, Nemets A, Ben-Dor D, Nahlieli O. Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity. Am J Med. 2004;117:440-441.
    • (2004) Am J Med , vol.117 , pp. 440-441
    • Lugassy, G.1    Shaham, R.2    Nemets, A.3    Ben-Dor, D.4    Nahlieli, O.5
  • 21
    • 33845234810 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in newly diagnosed multiple myeloma patients treated with zoledronic acid and thalidomide-dexamethasone
    • Tosi P, Zamagni E, Cangini D, et al. Osteonecrosis of the jaws in newly diagnosed multiple myeloma patients treated with zoledronic acid and thalidomide-dexamethasone. Blood. 2006;108:3951-3952.
    • (2006) Blood , vol.108 , pp. 3951-3952
    • Tosi, P.1    Zamagni, E.2    Cangini, D.3
  • 22
    • 33847337017 scopus 로고    scopus 로고
    • Bisphosphonates and osteonecrosis of the jaws: Incidence in a homogeneous series of patients with newly diagnosed multiple myeloma treated with zoledronic acid [abstract]
    • Tosi P, Zamagni E, Cangini D, et al. Bisphosphonates and osteonecrosis of the jaws: incidence in a homogeneous series of patients with newly diagnosed multiple myeloma treated with zoledronic acid [abstract]. Blood. 2005;106:3461.
    • (2005) Blood , vol.106 , pp. 3461
    • Tosi, P.1    Zamagni, E.2    Cangini, D.3
  • 23
    • 33646890244 scopus 로고    scopus 로고
    • Migliorati CA, Siegel MA, Elting LS. Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment [published correction appears in Lancet Oncol. 2006;7:533]. Lancet Oncol. 2006;7: 508-514.
    • Migliorati CA, Siegel MA, Elting LS. Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment [published correction appears in Lancet Oncol. 2006;7:533]. Lancet Oncol. 2006;7: 508-514.
  • 24
    • 23844478623 scopus 로고    scopus 로고
    • The effects of suppressed bone remodeling by bisphosphonates on microdamage accumulation and degree of mineralization in the cortical bone of dog rib
    • Mashiba T, Mori S, Burr DB, et al. The effects of suppressed bone remodeling by bisphosphonates on microdamage accumulation and degree of mineralization in the cortical bone of dog rib. J Bone Miner Metab. 2005; 23(suppl):36-42.
    • (2005) J Bone Miner Metab , vol.23 , Issue.SUPPL. , pp. 36-42
    • Mashiba, T.1    Mori, S.2    Burr, D.B.3
  • 25
    • 0028006777 scopus 로고
    • Optimal frequency of administration of pamidronate in patients with hypercalcaemia of malignancy
    • Wimalawansa SJ. Optimal frequency of administration of pamidronate in patients with hypercalcaemia of malignancy. Clin Endocrinol (Oxf). 1994;41:591-595.
    • (1994) Clin Endocrinol (Oxf) , vol.41 , pp. 591-595
    • Wimalawansa, S.J.1
  • 26
    • 33646836925 scopus 로고    scopus 로고
    • Woo SB, Hellstein JW, Kalmar JR. Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws [published correction appears in Ann Intern Med. 2006;145:235]. Ann Intern Med. 2006;144:753-761.
    • Woo SB, Hellstein JW, Kalmar JR. Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws [published correction appears in Ann Intern Med. 2006;145:235]. Ann Intern Med. 2006;144:753-761.
  • 27
    • 21444449880 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw and bisphosphonates [with discussion]
    • Woo SB, Hande K, Richardson PG. Osteonecrosis of the jaw and bisphosphonates [with discussion]. N Engl J Med. 2005;353:99-102.
    • (2005) N Engl J Med , vol.353 , pp. 99-102
    • Woo, S.B.1    Hande, K.2    Richardson, P.G.3
  • 28
    • 0035004850 scopus 로고    scopus 로고
    • Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles
    • Mashiba T, Turner CH, Hirano T, Forwood MR, Johnston CC, Burr DB. Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles. Bone. 2001;28:524-531.
    • (2001) Bone , vol.28 , pp. 524-531
    • Mashiba, T.1    Turner, C.H.2    Hirano, T.3    Forwood, M.R.4    Johnston, C.C.5    Burr, D.B.6
  • 29
    • 0042861578 scopus 로고    scopus 로고
    • Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic
    • Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003;61:1115-1117.
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1115-1117
    • Marx, R.E.1
  • 30
    • 24144465755 scopus 로고    scopus 로고
    • Osteonecrosis of jaw in patient with hormone-refractory prostate cancer treated with zoledronic acid
    • Olson KB, Hellie CM, Pienta KJ. Osteonecrosis of jaw in patient with hormone-refractory prostate cancer treated with zoledronic acid. Urology. 2005;66:658.
    • (2005) Urology , vol.66 , pp. 658
    • Olson, K.B.1    Hellie, C.M.2    Pienta, K.J.3
  • 31
    • 33746190668 scopus 로고    scopus 로고
    • Bone-directed treatments for prostate cancer
    • Saad F. Bone-directed treatments for prostate cancer. Hematol Oncol Clin North Am. 2006;20:947-963.
    • (2006) Hematol Oncol Clin North Am , vol.20 , pp. 947-963
    • Saad, F.1
  • 33
    • 34147095972 scopus 로고    scopus 로고
    • Critical review: Updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients - May 2006
    • Weitzman R, Sauter N, Eriksen EF, et al. Critical review: updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients - May 2006. Crit Rev Oncol Hematol. 2007;62:148-152.
    • (2007) Crit Rev Oncol Hematol , vol.62 , pp. 148-152
    • Weitzman, R.1    Sauter, N.2    Eriksen, E.F.3
  • 34
    • 33646871599 scopus 로고    scopus 로고
    • Jaw complications associated with bisphosphonate use in patients with plasma cell dyscrasias
    • Thakkar SG, Isada C, Smith J, et al. Jaw complications associated with bisphosphonate use in patients with plasma cell dyscrasias. Med Oncol. 2006;23:51-56.
    • (2006) Med Oncol , vol.23 , pp. 51-56
    • Thakkar, S.G.1    Isada, C.2    Smith, J.3
  • 35
    • 0041358697 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws associated with cancer chemotherapy
    • Wang J, Goodger NM, Pogrel MA. Osteonecrosis of the jaws associated with cancer chemotherapy. J Oral Maxillofac Surg. 2003;61:1104-1107.
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1104-1107
    • Wang, J.1    Goodger, N.M.2    Pogrel, M.A.3
  • 36
    • 48749104807 scopus 로고    scopus 로고
    • Insight into bisphosphonate-associated osteomyelitis of the jaw: Pathophysiology, mechanisms and clinical management
    • Wimalawansa SJ. Insight into bisphosphonate-associated osteomyelitis of the jaw: pathophysiology, mechanisms and clinical management. Expert Opin Drug Saf. 2008;7:491-512.
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 491-512
    • Wimalawansa, S.J.1
  • 37
    • 84901794372 scopus 로고    scopus 로고
    • Accessed for verification September 7, 2008
    • Chang JS. ODS Postmarketing Safety Review. 2004. http://www.fda.gov/ohrms/dockets/ac/05/briefing/2005-4095B2-03-04-FDA-TAB3.pdf. Accessed for verification September 7, 2008.
    • ODS Postmarketing Safety Review. 2004
    • Chang, J.S.1
  • 38
    • 33645242370 scopus 로고    scopus 로고
    • Osteonecrosis of the mandible or maxilla associated with the use of new generation bisphosphonates
    • Farrugia MC, Summerlin DJ, Krowiak E, et al. Osteonecrosis of the mandible or maxilla associated with the use of new generation bisphosphonates. Laryngoscope. 2006;116:115-120.
    • (2006) Laryngoscope , vol.116 , pp. 115-120
    • Farrugia, M.C.1    Summerlin, D.J.2    Krowiak, E.3
  • 39
    • 29144519913 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in patients with a history of receiving bisphosphonate therapy: Strategies for prevention and early recognition
    • Melo MD, Obeid G. Osteonecrosis of the jaws in patients with a history of receiving bisphosphonate therapy: strategies for prevention and early recognition. J Am Dent Assoc. 2005;36:1675-1681.
    • (2005) J Am Dent Assoc , vol.36 , pp. 1675-1681
    • Melo, M.D.1    Obeid, G.2
  • 40
    • 85036787661 scopus 로고    scopus 로고
    • Food and Drug Administration Center for Drug Evaluation and Research Oncologic Drugs Advisory Committee meeting March 4, 2005: questions to the committee, Accessed for verification September 7, 2008
    • Food and Drug Administration Center for Drug Evaluation and Research Oncologic Drugs Advisory Committee meeting March 4, 2005: questions to the committee. http://www.fda.gov/ohrms/dockets/ac/05/questions/2005-4095Q2-02- Zometa-Aredia-Questions. pdf. Accessed for verification September 7, 2008.
  • 41
    • 33748558131 scopus 로고    scopus 로고
    • Dental management of patients receiving oral bisphosphonate therapy: Expert panel recommendations
    • American Dental Association Council on Scientific Affairs
    • American Dental Association Council on Scientific Affairs. Dental management of patients receiving oral bisphosphonate therapy: expert panel recommendations. J Am Dent Assoc. 2006;137:1144-1150.
    • (2006) J Am Dent Assoc , vol.137 , pp. 1144-1150
  • 42
    • 33751528987 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw - do bisphosphonates pose a risk?
    • Bilezikian JP. Osteonecrosis of the jaw - do bisphosphonates pose a risk? N Engl J Med. 2006;355:2278-2281.
    • (2006) N Engl J Med , vol.355 , pp. 2278-2281
    • Bilezikian, J.P.1
  • 43
    • 85036778230 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration. MedWatch 2004 Safety Alerts for Drugs, Biologics, Medical Devices, and Dietary Supplements: Zometa (zoledronic acid) injection. http://www.fda.gov/medwatch/SAFETY/2004/safety04.htm#zometa. Accessed for verification September 7, 2008.
    • U.S. Food and Drug Administration. MedWatch 2004 Safety Alerts for Drugs, Biologics, Medical Devices, and Dietary Supplements: Zometa (zoledronic acid) injection. http://www.fda.gov/medwatch/SAFETY/2004/safety04.htm#zometa. Accessed for verification September 7, 2008.
  • 44
    • 34848841461 scopus 로고    scopus 로고
    • (American Society for Bone andMineral Research). Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • Khosla S, Burr D, Cauley J, et al (American Society for Bone andMineral Research). Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22:1479-1491.
    • (2007) J Bone Miner Res , vol.22 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 45
    • 33646015087 scopus 로고    scopus 로고
    • diagnosis, and treatment of osteonecrosis of the jaws
    • Expert panel recommendations for the prevention
    • Expert panel recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaws. LDA J. 2005;64:21-24.
    • (2005) LDA J , vol.64 , pp. 21-24
  • 46
    • 18944388211 scopus 로고    scopus 로고
    • Osteonecrosis of the maxilla in a patient with a history of bisphosphonate therapy
    • Melo MD, Obeid G. Osteonecrosis of the maxilla in a patient with a history of bisphosphonate therapy. J Can Dent Assoc. 2005;71:111-113.
    • (2005) J Can Dent Assoc , vol.71 , pp. 111-113
    • Melo, M.D.1    Obeid, G.2
  • 47
    • 85036795649 scopus 로고    scopus 로고
    • American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. September 25, 2006, Accessed for verification December 18, 2008
    • American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. September 25, 2006. http://www.aaoms.org/docs/position-papers/osteonecrosis.pdf. Accessed for verification December 18, 2008.
  • 48
    • 27244454807 scopus 로고    scopus 로고
    • Jaw bone necrosis without previous dental extractions associated with the use of bisphosphonates (pamidronate and zoledronate): A four-case report
    • Merigo E, Manfredi M, Meleti M, Corradi D, Vescovi P. Jaw bone necrosis without previous dental extractions associated with the use of bisphosphonates (pamidronate and zoledronate): a four-case report. J Oral Pathol Med. 2005;34:613-617.
    • (2005) J Oral Pathol Med , vol.34 , pp. 613-617
    • Merigo, E.1    Manfredi, M.2    Meleti, M.3    Corradi, D.4    Vescovi, P.5
  • 49
    • 0025310023 scopus 로고    scopus 로고
    • Harrison M, James N, Broadley K, et al. Somatostatin analogue treatment for malignant hypercalcaemia [published correction appears in BMJ. 1990;301:97]. BMJ. 1990;300:1313-1314.
    • Harrison M, James N, Broadley K, et al. Somatostatin analogue treatment for malignant hypercalcaemia [published correction appears in BMJ. 1990;301:97]. BMJ. 1990;300:1313-1314.
  • 50
    • 0028297667 scopus 로고
    • Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate
    • Wimalawansa SJ. Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate. Cancer. 1994;73:2223-2230.
    • (1994) Cancer , vol.73 , pp. 2223-2230
    • Wimalawansa, S.J.1
  • 51
    • 3743149878 scopus 로고
    • Hypercalcaemia of malignancy: Etiology, pathophysiology, and management
    • Wimalawansa S. Hypercalcaemia of malignancy: etiology, pathophysiology, and management. Rev Endocr Relat Cancer. 1993;45:5-24.
    • (1993) Rev Endocr Relat Cancer , vol.45 , pp. 5-24
    • Wimalawansa, S.1
  • 53
    • 33750733277 scopus 로고    scopus 로고
    • Molecular mechanisms of action of bisphosphonates: Current status
    • Roelofs AJ, Thompson K, Gordon S, Rogers MJ. Molecular mechanisms of action of bisphosphonates: current status. Clin Cancer Res. 2006;12(20, pt 2):6222s-6230s.
    • (2006) Clin Cancer Res , vol.12 , Issue.20 and PART 2
    • Roelofs, A.J.1    Thompson, K.2    Gordon, S.3    Rogers, M.J.4
  • 54
    • 0036123845 scopus 로고    scopus 로고
    • Promotion of osteoclast survival and antagonism of bisphosphonateinduced osteoclast apoptosis by glucocorticoids
    • Weinstein RS, Chen JR, Powers CC, et al. Promotion of osteoclast survival and antagonism of bisphosphonateinduced osteoclast apoptosis by glucocorticoids. J Clin Invest. 2002;109:1041-1048.
    • (2002) J Clin Invest , vol.109 , pp. 1041-1048
    • Weinstein, R.S.1    Chen, J.R.2    Powers, C.C.3
  • 56
    • 0032528180 scopus 로고    scopus 로고
    • Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids: Potential mechanisms of their deleterious effects on bone
    • Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC. Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids: potential mechanisms of their deleterious effects on bone. J Clin Invest. 1998;102:274-282.
    • (1998) J Clin Invest , vol.102 , pp. 274-282
    • Weinstein, R.S.1    Jilka, R.L.2    Parfitt, A.M.3    Manolagas, S.C.4
  • 57
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev. 2000;21: 115-137.
    • (2000) Endocr Rev , vol.21 , pp. 115-137
    • Manolagas, S.C.1
  • 58
    • 26844545023 scopus 로고    scopus 로고
    • Sarathy AP, Bourgeois SL Jr, Goodell GG. Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports [published correction appears in J Endod. 2005;31:835-836]. J Endod. 2005;31:759-763.
    • Sarathy AP, Bourgeois SL Jr, Goodell GG. Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports [published correction appears in J Endod. 2005;31:835-836]. J Endod. 2005;31:759-763.
  • 59
    • 21244475168 scopus 로고    scopus 로고
    • Patients receiving intravenous bisphosphonates should avoid invasive dental procedures
    • Wooltorton E. Patients receiving intravenous bisphosphonates should avoid invasive dental procedures. CMAJ. 2005;172:1684.
    • (2005) CMAJ , vol.172 , pp. 1684
    • Wooltorton, E.1
  • 60
    • 33751538274 scopus 로고    scopus 로고
    • Images in clinical medicine: Bisphosphonate-associated osteonecrosis of the jaw
    • Treister N, Woo SB. Images in clinical medicine: bisphosphonate-associated osteonecrosis of the jaw. N Engl J Med. 2006;355:2348.
    • (2006) N Engl J Med , vol.355 , pp. 2348
    • Treister, N.1    Woo, S.B.2
  • 61
    • 34547612321 scopus 로고    scopus 로고
    • Is bisphosphonate-associated osteonecrosis of the jaw caused by soft tissue toxicity?
    • Reid IR, Bolland MJ, Grey AB. Is bisphosphonate-associated osteonecrosis of the jaw caused by soft tissue toxicity? Bone. 2007;41:318-320.
    • (2007) Bone , vol.41 , pp. 318-320
    • Reid, I.R.1    Bolland, M.J.2    Grey, A.B.3
  • 62
    • 33645229970 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis
    • Hansen T, KunkelM,Weber A, James Kirkpatrick C. Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis. J Oral Pathol Med. 2006;35:155-160.
    • (2006) J Oral Pathol Med , vol.35 , pp. 155-160
    • Hansen, T.1    KunkelM2    Weber, A.3    James Kirkpatrick, C.4
  • 63
    • 34247586576 scopus 로고    scopus 로고
    • Zoledronic acid has direct antiproliferative and antimetastatic effect on pancreatic carcinoma cells and acts as an antigen for delta2 gamma/delta T cells
    • Märten A, Lilienfeld-Toal M, Büchler MW, Schmidt J. Zoledronic acid has direct antiproliferative and antimetastatic effect on pancreatic carcinoma cells and acts as an antigen for delta2 gamma/delta T cells. J Immunother. 2007;30:370-377.
    • (2007) J Immunother , vol.30 , pp. 370-377
    • Märten, A.1    Lilienfeld-Toal, M.2    Büchler, M.W.3    Schmidt, J.4
  • 64
    • 33748804427 scopus 로고    scopus 로고
    • The effect of zoledronic acid on the function and differentiation of myeloid cells
    • Wolf AM, Rumpold H, Tilg H, Gastl G, Gunsilius E, Wolf D. The effect of zoledronic acid on the function and differentiation of myeloid cells. Haematologica. 2006;91:1165-1171.
    • (2006) Haematologica , vol.91 , pp. 1165-1171
    • Wolf, A.M.1    Rumpold, H.2    Tilg, H.3    Gastl, G.4    Gunsilius, E.5    Wolf, D.6
  • 65
    • 34547638252 scopus 로고    scopus 로고
    • Targeting human gammadelta T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer
    • Dieli F, Vermijlen D, Fulfaro F, et al. Targeting human gammadelta T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer. Cancer Res. 2007;67:7450-7457.
    • (2007) Cancer Res , vol.67 , pp. 7450-7457
    • Dieli, F.1    Vermijlen, D.2    Fulfaro, F.3
  • 66
    • 20444445149 scopus 로고    scopus 로고
    • Cytotoxic effects of gammadelta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy
    • Sato K, Kimura S, Segawa H, et al. Cytotoxic effects of gammadelta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy. Int J Cancer. 2005;116:94-99.
    • (2005) Int J Cancer , vol.116 , pp. 94-99
    • Sato, K.1    Kimura, S.2    Segawa, H.3
  • 67
    • 37049006066 scopus 로고    scopus 로고
    • Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
    • Melani C, Sangaletti S, Barazzetta FM, Werb Z, Colombo MP. Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res. 2007;67:11438-11446.
    • (2007) Cancer Res , vol.67 , pp. 11438-11446
    • Melani, C.1    Sangaletti, S.2    Barazzetta, F.M.3    Werb, Z.4    Colombo, M.P.5
  • 68
    • 34547962875 scopus 로고    scopus 로고
    • Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid
    • Fiore F, Castella B, Nuschak B, et al. Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid. Blood. 2007;110:921-927.
    • (2007) Blood , vol.110 , pp. 921-927
    • Fiore, F.1    Castella, B.2    Nuschak, B.3
  • 69
    • 34848841461 scopus 로고    scopus 로고
    • (American Society for Bone andMineral Research). Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • Khosla S, Burr D, Cauley J, et al (American Society for Bone andMineral Research). Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22:1479-1491.
    • (2007) J Bone Miner Res , vol.22 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 70
    • 85036787939 scopus 로고    scopus 로고
    • Cafro A, Barbarano LA, Andriani A, et al. Osteonecrosis of the jaw associated with chronic bisphosphonate therapy: an Italian experience [American Society of Hematology Annual Meeting Abstracts]. Blood. 2005;106:5152.
    • Cafro A, Barbarano LA, Andriani A, et al. Osteonecrosis of the jaw associated with chronic bisphosphonate therapy: an Italian experience [American Society of Hematology Annual Meeting Abstracts]. Blood. 2005;106:5152.
  • 71
    • 18044392927 scopus 로고    scopus 로고
    • Bisphosphonate osteochemonecrosis (bis-phossy jaw): Is this phossy jaw of the 21st century?
    • Hellstein JW, Marek CL. Bisphosphonate osteochemonecrosis (bis-phossy jaw): is this phossy jaw of the 21st century? J Oral Maxillofac Surg. 2005;63:682-689.
    • (2005) J Oral Maxillofac Surg , vol.63 , pp. 682-689
    • Hellstein, J.W.1    Marek, C.L.2
  • 72
    • 85036772541 scopus 로고    scopus 로고
    • The Maxillofacial Center for Diagnostics & Research, Accessed for verification September 7, 2008
    • The Maxillofacial Center for Diagnostics & Research. The History of Maxillofacial Osteonecrosis (NICO). http://maxillofacialcenter.com/ NICOhistory.html#Histo ry. Accessed for verification September 7, 2008.
    • The History of Maxillofacial Osteonecrosis (NICO)
  • 73
    • 85036773475 scopus 로고    scopus 로고
    • Merck & Co., Inc. Fosamax (alendronate sodium) tablets and oral solution. Whitehouse Station, NJ; February 2006. http://www.fosamax.com/ fosamax/shared/documents/english/pi.pdf. Accessed for verification September 7, 2008.
    • Merck & Co., Inc. Fosamax (alendronate sodium) tablets and oral solution. Whitehouse Station, NJ; February 2006. http://www.fosamax.com/ fosamax/shared/documents/english/pi.pdf. Accessed for verification September 7, 2008.
  • 74
    • 34247866550 scopus 로고    scopus 로고
    • (HORIZON Pivotal Fracture Trial). Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
    • Black DM, Delmas PD, Eastell R, et al (HORIZON Pivotal Fracture Trial). Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med. 2007;356:1809-1822.
    • (2007) N Engl J Med , vol.356 , pp. 1809-1822
    • Black, D.M.1    Delmas, P.D.2    Eastell, R.3
  • 75
    • 35748967004 scopus 로고    scopus 로고
    • (HORIZON Recurrent Fracture Trial). Zoledronic acid and clinical fractures and mortality after hip fracture
    • Lyles KW, Colón-Emeric CS, Magaziner JS, et al (HORIZON Recurrent Fracture Trial). Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med. 2007;357:1799-1809.
    • (2007) N Engl J Med , vol.357 , pp. 1799-1809
    • Lyles, K.W.1    Colón-Emeric, C.S.2    Magaziner, J.S.3
  • 76
    • 34247218044 scopus 로고    scopus 로고
    • (Gruppo Italiano Studio Linfomi). Bisphosphonate-associated osteonecrosis of the jaw: A review of 35 cases and an evaluation of its frequency in multiple myeloma patients
    • Pozzi S, Marcheselli R, Sacchi S, et al (Gruppo Italiano Studio Linfomi). Bisphosphonate-associated osteonecrosis of the jaw: a review of 35 cases and an evaluation of its frequency in multiple myeloma patients. Leuk Lymphoma. 2007;48:56-64.
    • (2007) Leuk Lymphoma , vol.48 , pp. 56-64
    • Pozzi, S.1    Marcheselli, R.2    Sacchi, S.3
  • 77
    • 15944381175 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw associated with zoledronate therapy in a patient with multiple myeloma
    • Vannucchi AM, Ficarra G, Antonioli E, Bosi A. Osteonecrosis of the jaw associated with zoledronate therapy in a patient with multiple myeloma. Br J Haematol. 2005; 128:738.
    • (2005) Br J Haematol , vol.128 , pp. 738
    • Vannucchi, A.M.1    Ficarra, G.2    Antonioli, E.3    Bosi, A.4
  • 78
    • 85036781611 scopus 로고    scopus 로고
    • Mehrotra B, Ruggiero SL. Bisphosphonate related osteonecrosis (BRON) of the jaw: single institutional update [American Society of Hematology Annual Meeting Abstracts]. Blood. 2005;106:291.
    • Mehrotra B, Ruggiero SL. Bisphosphonate related osteonecrosis (BRON) of the jaw: single institutional update [American Society of Hematology Annual Meeting Abstracts]. Blood. 2005;106:291.
  • 79
    • 0031800001 scopus 로고    scopus 로고
    • Avascular necrosis of bone - a complication of aggressive therapy for acute lymphoblastic leukemia
    • Vaidya S, Saika S, Sirohi B, Pai S, Advani S. Avascular necrosis of bone - a complication of aggressive therapy for acute lymphoblastic leukemia. Acta Oncol. 1998;37:175-177.
    • (1998) Acta Oncol , vol.37 , pp. 175-177
    • Vaidya, S.1    Saika, S.2    Sirohi, B.3    Pai, S.4    Advani, S.5
  • 80
    • 33745142168 scopus 로고    scopus 로고
    • Bisphosphonates are associated with increased risk for jaw surgery in medical claims data: Is it osteonecrosis?
    • Zavras AI, Zhu S. Bisphosphonates are associated with increased risk for jaw surgery in medical claims data: is it osteonecrosis? J Oral Maxillofac Surg. 2006;64:917-923.
    • (2006) J Oral Maxillofac Surg , vol.64 , pp. 917-923
    • Zavras, A.I.1    Zhu, S.2
  • 81
    • 33644841755 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors
    • Bamias A, Kastritis E, Bamia C, et al. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors. J Clin Oncol. 2005;23:8580-8587.
    • (2005) J Clin Oncol , vol.23 , pp. 8580-8587
    • Bamias, A.1    Kastritis, E.2    Bamia, C.3
  • 82
    • 21444449880 scopus 로고    scopus 로고
    • Maerevoet M, Martin C, Duck L. Osteonecrosis of the jaw and bisphosphonates [with discussion] [published correction appears in N Engl J Med. 2005;353:2728]. N Engl J Med. 2005;353:99-102.
    • Maerevoet M, Martin C, Duck L. Osteonecrosis of the jaw and bisphosphonates [with discussion] [published correction appears in N Engl J Med. 2005;353:2728]. N Engl J Med. 2005;353:99-102.
  • 83
    • 29144473495 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaws: A review of current knowledge
    • Markiewicz MR, Margarone JE III, Campbell JH, Aguirre A. Bisphosphonate-associated osteonecrosis of the jaws: a review of current knowledge. J Am Dent Assoc. 2005;136:1669-1674.
    • (2005) J Am Dent Assoc , vol.136 , pp. 1669-1674
    • Markiewicz, M.R.1    Margarone III, J.E.2    Campbell, J.H.3    Aguirre, A.4
  • 84
    • 0346186206 scopus 로고    scopus 로고
    • Bisphosphonate therapy in the oncology setting
    • Lipton A. Bisphosphonate therapy in the oncology setting. Expert Opin Emerg Drugs. 2003;8:469-488.
    • (2003) Expert Opin Emerg Drugs , vol.8 , pp. 469-488
    • Lipton, A.1
  • 86
    • 33847173476 scopus 로고    scopus 로고
    • Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia
    • Mavrokokki T, Cheng A, Stein B, Goss A. Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia. J Oral Maxillofac Surg. 2007;65: 415-423.
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 415-423
    • Mavrokokki, T.1    Cheng, A.2    Stein, B.3    Goss, A.4
  • 88
    • 10744227993 scopus 로고    scopus 로고
    • Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients
    • Santini D, Vincenzi B, Dicuonzo G, et al. Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. Clin Cancer Res. 2003;9:2893-2897.
    • (2003) Clin Cancer Res , vol.9 , pp. 2893-2897
    • Santini, D.1    Vincenzi, B.2    Dicuonzo, G.3
  • 89
    • 1542376857 scopus 로고    scopus 로고
    • Bisphosphonates and bone necrosis
    • Pogrel MA. Bisphosphonates and bone necrosis. J Oral Maxillofac Surg. 2004;62:391-392.
    • (2004) J Oral Maxillofac Surg , vol.62 , pp. 391-392
    • Pogrel, M.A.1
  • 90
    • 2942623958 scopus 로고    scopus 로고
    • Osteonecrosis and bisphosphonates: Correlation versus causation
    • Schwartz HC. Osteonecrosis and bisphosphonates: correlation versus causation. J Oral Maxillofac Surg. 2004; 62:763-764.
    • (2004) J Oral Maxillofac Surg , vol.62 , pp. 763-764
    • Schwartz, H.C.1
  • 91
    • 0027131843 scopus 로고
    • Treatment of hypercalcaemia with pamidronate in patients with end stage renal failure
    • Davenport A, Goel S, Mackenzie JC. Treatment of hypercalcaemia with pamidronate in patients with end stage renal failure. Scand J Urol Nephrol. 1993;27:447-451.
    • (1993) Scand J Urol Nephrol , vol.27 , pp. 447-451
    • Davenport, A.1    Goel, S.2    Mackenzie, J.C.3
  • 92
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M, et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer. 2003;98:1735-1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 93
    • 33646942734 scopus 로고    scopus 로고
    • Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy
    • Soileau KM. Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy. J Periodontol. 2006;77:738-743.
    • (2006) J Periodontol , vol.77 , pp. 738-743
    • Soileau, K.M.1
  • 94
    • 0642316721 scopus 로고    scopus 로고
    • Bisphosphonates and oral cavity avascular bone necrosis
    • Migliorati CA. Bisphosphonates and oral cavity avascular bone necrosis. J Clin Oncol. 2003;21:4253-4254.
    • (2003) J Clin Oncol , vol.21 , pp. 4253-4254
    • Migliorati, C.A.1
  • 95
    • 33746855407 scopus 로고    scopus 로고
    • Mayo Clinic consensus statement for the use of bisphosphonates in multiple myeloma
    • LacyMQ, Dispenzieri A, GertzMA, et al. Mayo Clinic consensus statement for the use of bisphosphonates in multiple myeloma. Mayo Clin Proc. 2006;81:1047-1053.
    • (2006) Mayo Clin Proc , vol.81 , pp. 1047-1053
    • Lacy, M.Q.1    Dispenzieri, A.2    Gertz, M.A.3
  • 96
    • 0142025453 scopus 로고    scopus 로고
    • Renal failure with the use of zoledronic acid [with discussion]
    • Chang JT, Green L, Beitz J. Renal failure with the use of zoledronic acid [with discussion]. N Engl J Med. 2003; 349:1676-1679.
    • (2003) N Engl J Med , vol.349 , pp. 1676-1679
    • Chang, J.T.1    Green, L.2    Beitz, J.3
  • 97
    • 2442632814 scopus 로고    scopus 로고
    • Short-term, high-dose pamidronate-induced acute tubular necrosis: The postulated mechanisms of bisphosphonate nephrotoxicity
    • Banerjee D, Asif A, Striker L, Preston RA, Bourgoignie JJ, Roth D. Short-term, high-dose pamidronate-induced acute tubular necrosis: the postulated mechanisms of bisphosphonate nephrotoxicity. Am J Kidney Dis. 2003;41:E18.
    • (2003) Am J Kidney Dis , vol.41
    • Banerjee, D.1    Asif, A.2    Striker, L.3    Preston, R.A.4    Bourgoignie, J.J.5    Roth, D.6
  • 98
    • 85036777749 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals Corporation. Aredia product information. East Hanover, NJ; November 2007. http://www.pharma.us.novartis.com/product/pi/ pdf/aredia.pdf. Accessed for verification September 7, 2008.
    • Novartis Pharmaceuticals Corporation. Aredia product information. East Hanover, NJ; November 2007. http://www.pharma.us.novartis.com/product/pi/ pdf/aredia.pdf. Accessed for verification September 7, 2008.
  • 99
    • 0029874568 scopus 로고    scopus 로고
    • Safety of pamidronate in patients with renal failure and hypercalcemia
    • Machado CE, Flombaum CD. Safety of pamidronate in patients with renal failure and hypercalcemia. Clin Nephrol. 1996;45:175-179.
    • (1996) Clin Nephrol , vol.45 , pp. 175-179
    • Machado, C.E.1    Flombaum, C.D.2
  • 100
    • 0035007762 scopus 로고    scopus 로고
    • Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate
    • Markowitz GS, Appel GB, Fine PL, et al. Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate. J Am Soc Nephrol. 2001;12: 1164-1172.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1164-1172
    • Markowitz, G.S.1    Appel, G.B.2    Fine, P.L.3
  • 101
    • 10744228141 scopus 로고    scopus 로고
    • Toxic acute tubular necrosis following treatment with zoledronate (Zometa)
    • Markowitz GS, Fine PL, Stack JI, et al. Toxic acute tubular necrosis following treatment with zoledronate (Zometa). Kidney Int. 2003;64:281-289.
    • (2003) Kidney Int , vol.64 , pp. 281-289
    • Markowitz, G.S.1    Fine, P.L.2    Stack, J.I.3
  • 102
    • 21744455759 scopus 로고    scopus 로고
    • Zoledronic acid and renal toxicity: Data from French adverse effect reporting database
    • Munier A, Gras V, Andrejak M, et al. Zoledronic acid and renal toxicity: data from French adverse effect reporting database. Ann Pharmacother. 2005;39:1194-1197.
    • (2005) Ann Pharmacother , vol.39 , pp. 1194-1197
    • Munier, A.1    Gras, V.2    Andrejak, M.3
  • 103
    • 33847252075 scopus 로고    scopus 로고
    • Analysis of frequency and risk factors for developing bisphosphonate associated osteonecrosis of the jaw
    • Pozzi S, Marcheselli R, Sacchi S. Analysis of frequency and risk factors for developing bisphosphonate associated osteonecrosis of the jaw. Blood. 2005;106:5057a.
    • (2005) Blood , vol.106
    • Pozzi, S.1    Marcheselli, R.2    Sacchi, S.3
  • 104
    • 33744824912 scopus 로고    scopus 로고
    • Long-term safety of bisphosphonate therapy for osteoporosis: A review of the evidence
    • Liberman UA. Long-term safety of bisphosphonate therapy for osteoporosis: a review of the evidence. Drugs Aging. 2006;23:289-298.
    • (2006) Drugs Aging , vol.23 , pp. 289-298
    • Liberman, U.A.1
  • 105
    • 33749678428 scopus 로고    scopus 로고
    • Beyond bisphosphonates: Thrombophilia, hypofibrinolysis, and jaw osteonecrosis
    • McMahon RE, Bouquot JE, Glueck CJ, Griep J. Beyond bisphosphonates: thrombophilia, hypofibrinolysis, and jaw osteonecrosis. J Oral Maxillofac Surg. 2006;64:1704-1705.
    • (2006) J Oral Maxillofac Surg , vol.64 , pp. 1704-1705
    • McMahon, R.E.1    Bouquot, J.E.2    Glueck, C.J.3    Griep, J.4
  • 107
    • 34547588611 scopus 로고    scopus 로고
    • Recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates
    • Bagán J, Blade J, Cozar JM, et al. Recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates. Med Oral Patol Oral Cir Bucal. 2007;12:E336-E340.
    • (2007) Med Oral Patol Oral Cir Bucal , vol.12
    • Bagán, J.1    Blade, J.2    Cozar, J.M.3
  • 108
    • 33749071657 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: A literature review and clinical practice guidelines
    • Pickett FA American Academy of Oral Medicine
    • Pickett FA (American Academy of Oral Medicine). Bisphosphonate-associated osteonecrosis of the jaw: a literature review and clinical practice guidelines. J Dent Hyg. 2006;80:10.
    • (2006) J Dent Hyg , vol.80 , pp. 10
  • 109
    • 0036100779 scopus 로고    scopus 로고
    • Alendronate in the treatment of avascular necrosis of the hip
    • Agarwala S, Sule A, Pai BU, Joshi VR. Alendronate in the treatment of avascular necrosis of the hip. Rheumatology (Oxford). 2002;41:346-347.
    • (2002) Rheumatology (Oxford) , vol.41 , pp. 346-347
    • Agarwala, S.1    Sule, A.2    Pai, B.U.3    Joshi, V.R.4
  • 111
    • 10544228130 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases
    • Protocol 19 Aredia Breast Cancer Study Group
    • Hortobagyi GN, Theriault RL, Porter L, et al (Protocol 19 Aredia Breast Cancer Study Group). Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. N Engl J Med. 1996;335:1785-1791.
    • (1996) N Engl J Med , vol.335 , pp. 1785-1791
    • Hortobagyi, G.N.1    Theriault, R.L.2    Porter, L.3
  • 112
    • 32644455093 scopus 로고    scopus 로고
    • Jaw osteonecrosis associated with bisphosphonates: Multiple exposed areas and its relationship to teeth extractions; study of 20 cases
    • Bagan JV, Jimenez Y, Murillo J, et al. Jaw osteonecrosis associated with bisphosphonates: multiple exposed areas and its relationship to teeth extractions; study of 20 cases. Oral Oncol. 2006;42:327-329.
    • (2006) Oral Oncol , vol.42 , pp. 327-329
    • Bagan, J.V.1    Jimenez, Y.2    Murillo, J.3
  • 113
    • 27144437902 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment
    • Ficarra G, Beninati F, Rubino I, et al. Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment. J Clin Periodontol. 2005;32:1123-1128.
    • (2005) J Clin Periodontol , vol.32 , pp. 1123-1128
    • Ficarra, G.1    Beninati, F.2    Rubino, I.3
  • 114
    • 27644590803 scopus 로고    scopus 로고
    • Endodontic implications of bisphosphonate-associated osteonecrosis of the jaws: A report of three cases
    • Katz H. Endodontic implications of bisphosphonate-associated osteonecrosis of the jaws: a report of three cases. J Endod. 2005;31:831-834.
    • (2005) J Endod , vol.31 , pp. 831-834
    • Katz, H.1
  • 115
    • 43349085887 scopus 로고    scopus 로고
    • Multiple osteonecrosis of the jaw, oral bisphosphonate therapy and refractory rheumatoid arthritis (pathological fracture associated with ONJ and BP use for osteoporosis)
    • Grana J, Mahia IV, Meizoso MO, Vazquez T.Multiple osteonecrosis of the jaw, oral bisphosphonate therapy and refractory rheumatoid arthritis (pathological fracture associated with ONJ and BP use for osteoporosis). Clin Exp Rheumatol. 2008;26:384-385.
    • (2008) Clin Exp Rheumatol , vol.26 , pp. 384-385
    • Grana, J.1    Mahia, I.V.2    Meizoso, M.O.3    Vazquez, T.4
  • 116
    • 0029185592 scopus 로고
    • Failure of osseointegrated dental implants after diphosphonate therapy for osteoporosis: A case report
    • StarckWJ, Epker BN. Failure of osseointegrated dental implants after diphosphonate therapy for osteoporosis: a case report. Int J Oral Maxillofac Implants. 1995;10:74-78.
    • (1995) Int J Oral Maxillofac Implants , vol.10 , pp. 74-78
    • Starck, W.J.1    Epker, B.N.2
  • 118
    • 41249100756 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw
    • Watts NB, Marciani RD. Osteonecrosis of the jaw. South Med J. 2008;101:160-165.
    • (2008) South Med J , vol.101 , pp. 160-165
    • Watts, N.B.1    Marciani, R.D.2
  • 119
    • 33847284113 scopus 로고    scopus 로고
    • American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws
    • Advisory Task Force on Bisphosphonate-Related Osteonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons
    • Advisory Task Force on Bisphosphonate-Related Osteonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2007;65:369-376.
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 369-376
  • 120
    • 33744997201 scopus 로고    scopus 로고
    • Bisphosphonate- induced avascular osteonecrosis of the jaws: A clinical report of 11 cases
    • Dimitrakopoulos I, Magopoulos C, Karakasis D. Bisphosphonate- induced avascular osteonecrosis of the jaws: a clinical report of 11 cases. Int J Oral Maxillofac Surg. 2006;35:588-593.
    • (2006) Int J Oral Maxillofac Surg , vol.35 , pp. 588-593
    • Dimitrakopoulos, I.1    Magopoulos, C.2    Karakasis, D.3
  • 121
    • 33745792743 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: Evidence of increased risk after treatment with zoledronic acid
    • Dimopoulos MA, Kastritis E, Anagnostopoulos A, et al. Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: evidence of increased risk after treatment with zoledronic acid. Haematologica. 2006;91:968-971.
    • (2006) Haematologica , vol.91 , pp. 968-971
    • Dimopoulos, M.A.1    Kastritis, E.2    Anagnostopoulos, A.3
  • 122
    • 21444449880 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw and bisphosphonates [with discussion]
    • Durie BG, KatzM, Crowley J. Osteonecrosis of the jaw and bisphosphonates [with discussion]. N Engl J Med. 2005;353:99-102.
    • (2005) N Engl J Med , vol.353 , pp. 99-102
    • Durie, B.G.1    Katz, M.2    Crowley, J.3
  • 123
    • 12444268934 scopus 로고    scopus 로고
    • Avascular jaw osteonecrosis in association with cancer chemotherapy: Series of 10 cases
    • Bagan JV, Murillo J, Jimenez Y, et al. Avascular jaw osteonecrosis in association with cancer chemotherapy: series of 10 cases. J Oral Pathol Med. 2005;34:120-123.
    • (2005) J Oral Pathol Med , vol.34 , pp. 120-123
    • Bagan, J.V.1    Murillo, J.2    Jimenez, Y.3
  • 124
    • 33747879839 scopus 로고    scopus 로고
    • Bisphosphonates and osteonecrosis of the jaw: Cause and effect or a post hoc fallacy?
    • Van den Wyngaert T, Huizing MT, Vermorken JB. Bisphosphonates and osteonecrosis of the jaw: cause and effect or a post hoc fallacy? Ann Oncol. 2006;17:1197-1204.
    • (2006) Ann Oncol , vol.17 , pp. 1197-1204
    • Van den Wyngaert, T.1    Huizing, M.T.2    Vermorken, J.B.3
  • 125
    • 30444448703 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw associated with pamidronate therapy
    • Zarychanski R, Elphee E, Walton P, Johnston J. Osteonecrosis of the jaw associated with pamidronate therapy. Am J Hematol. 2006;81:73-75.
    • (2006) Am J Hematol , vol.81 , pp. 73-75
    • Zarychanski, R.1    Elphee, E.2    Walton, P.3    Johnston, J.4
  • 126
    • 43749089576 scopus 로고    scopus 로고
    • Factors associated with osteonecrosis of the jaw among bisphosphonate users
    • e3
    • Hess LM, Jeter JM, Benham-HutchinsM, Alberts DS. Factors associated with osteonecrosis of the jaw among bisphosphonate users. Am J Med. 2008;121:475-483; e3.
    • (2008) Am J Med , vol.121 , pp. 475-483
    • Hess, L.M.1    Jeter, J.M.2    HutchinsM, B.3    Alberts, D.S.4
  • 127
    • 43649090378 scopus 로고    scopus 로고
    • Khosla S, Burr D, Cauley J, et al (American Society for Bone and Mineral Research Task Force on Osteonecrosis of the Jaw). Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment [published correction appears in J Oral Maxillofac Surg. 2008;66:1778]. J Oral Maxillofac Surg. 2008;66:1320-1321.
    • Khosla S, Burr D, Cauley J, et al (American Society for Bone and Mineral Research Task Force on Osteonecrosis of the Jaw). Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment [published correction appears in J Oral Maxillofac Surg. 2008;66:1778]. J Oral Maxillofac Surg. 2008;66:1320-1321.
  • 128
    • 0038370949 scopus 로고    scopus 로고
    • Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review
    • Tauchmanovà L, De Rosa G, Serio B, et al. Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: a single center experience and a review. Cancer. 2003;97:2453-2461.
    • (2003) Cancer , vol.97 , pp. 2453-2461
    • Tauchmanovà, L.1    De Rosa, G.2    Serio, B.3
  • 129
    • 85031341096 scopus 로고    scopus 로고
    • For the dental patient: oral care for cancer patients. J Am Dent Assoc. 2002;133:1014.
    • For the dental patient: oral care for cancer patients. J Am Dent Assoc. 2002;133:1014.
  • 130
    • 77149180731 scopus 로고    scopus 로고
    • Long-term bisphosphonate therapy and increased fracture risks
    • Wimalawansa SJ. Long-term bisphosphonate therapy and increased fracture risks. J Bone Miner Res. 2007; 22(suppl 1):S456.
    • (2007) J Bone Miner Res , vol.22 , Issue.SUPPL. 1
    • Wimalawansa, S.J.1
  • 131
    • 25444476035 scopus 로고    scopus 로고
    • Jaw avascular bone necrosis associated with long-term use of biphosphonates
    • Sanna G, Zampino MG, Pelosi G, Nolè F, Goldhirsch A. Jaw avascular bone necrosis associated with long-term use of biphosphonates. Ann Oncol. 2005;16:1207-1208.
    • (2005) Ann Oncol , vol.16 , pp. 1207-1208
    • Sanna, G.1    Zampino, M.G.2    Pelosi, G.3    Nolè, F.4    Goldhirsch, A.5
  • 132
    • 33645457714 scopus 로고    scopus 로고
    • Mignogna MD, Fedele S, Lo Russo L, Ciccarelli R, Lo Muzio L. Case 2: osteonecrosis of the jaws associated with bisphosphonate therapy [published correction appears in J Clin Oncol. 2006;24:2687]. J Clin Oncol. 2006;24:1475-1477.
    • Mignogna MD, Fedele S, Lo Russo L, Ciccarelli R, Lo Muzio L. Case 2: osteonecrosis of the jaws associated with bisphosphonate therapy [published correction appears in J Clin Oncol. 2006;24:2687]. J Clin Oncol. 2006;24:1475-1477.
  • 133
    • 48749131546 scopus 로고    scopus 로고
    • Intermittent, intravenous pamidronate therapy: Highly effective treatment for postmenopausal osteoporosis; program and abstracts from the 23rd annual meeting of the American Society for Bone and Mineral Research; October 12-16, 2001; Phoenix, Arizona [abstract SU400]
    • Wimalawansa SJ. Intermittent, intravenous pamidronate therapy: highly effective treatment for postmenopausal osteoporosis; program and abstracts from the 23rd annual meeting of the American Society for Bone and Mineral Research; October 12-16, 2001; Phoenix, Arizona [abstract SU400]. J Bone Miner Res. 2001;16(suppl 1): S405.
    • (2001) J Bone Miner Res , vol.16 , Issue.SUPPL. 1
    • Wimalawansa, S.J.1
  • 134
    • 85036794850 scopus 로고    scopus 로고
    • Dimopoulos MA, Kastritis E, Bamia C, et al. Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid [published online ahead of print August 9, 2008]. Ann Oncol.
    • Dimopoulos MA, Kastritis E, Bamia C, et al. Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid [published online ahead of print August 9, 2008]. Ann Oncol.
  • 135
    • 44949251091 scopus 로고    scopus 로고
    • Bisphosphonates and ONJ [with author reply]
    • Etminan M, Aminzadeh K. Bisphosphonates and ONJ [with author reply]. J Am Dent Assoc. 2008;139:535-536.
    • (2008) J Am Dent Assoc , vol.139 , pp. 535-536
    • Etminan, M.1    Aminzadeh, K.2
  • 136
    • 38849175417 scopus 로고    scopus 로고
    • Closing in on the puzzle of ONJ
    • Glick M. Closing in on the puzzle of ONJ. J Am Dent Assoc. 2008;139:4-5.
    • (2008) J Am Dent Assoc , vol.139 , pp. 4-5
    • Glick, M.1
  • 137
    • 85036787701 scopus 로고    scopus 로고
    • La Verde N, Bareggi C, Garassino M, et al. Osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates: how the knowledge of a phenomenon can change its evolution [published online ahead of print July 29, 2008]. Support Care Cancer.
    • La Verde N, Bareggi C, Garassino M, et al. Osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates: how the knowledge of a phenomenon can change its evolution [published online ahead of print July 29, 2008]. Support Care Cancer.
  • 138
    • 33749234591 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw: More research needed
    • Shane E, Goldring S, Christakos S, et al. Osteonecrosis of the jaw: more research needed. J Bone Miner Res. 2006;21:1503-1505.
    • (2006) J Bone Miner Res , vol.21 , pp. 1503-1505
    • Shane, E.1    Goldring, S.2    Christakos, S.3
  • 140
    • 9044219839 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma
    • Myeloma Aredia Study Group
    • Berenson JR, Lichtenstein A, Porter L, et al (Myeloma Aredia Study Group). Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. N Engl J Med. 1996;334: 488-493.
    • (1996) N Engl J Med , vol.334 , pp. 488-493
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 142
    • 20544464439 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of mandibular and maxillary bone: An emerging oral complication of supportive cancer therapy
    • Migliorati CA, Schubert MM, Peterson DE, Seneda LM. Bisphosphonate-associated osteonecrosis of mandibular and maxillary bone: an emerging oral complication of supportive cancer therapy. Cancer. 2005; 104:83-93.
    • (2005) Cancer , vol.104 , pp. 83-93
    • Migliorati, C.A.1    Schubert, M.M.2    Peterson, D.E.3    Seneda, L.M.4
  • 144
    • 36048931674 scopus 로고    scopus 로고
    • Oral bisphosphonate-induced osteonecrosis: Risk factors, prediction of risk using serum CTX testing, prevention, and treatment
    • Marx RE, Cillo JE Jr, Ulloa JJ. Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg. 2007;65:2397-2410.
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 2397-2410
    • Marx, R.E.1    Cillo Jr, J.E.2    Ulloa, J.J.3
  • 145
    • 85036798999 scopus 로고    scopus 로고
    • Boniva ibandronate sodium injection, package insert, Nutley, NJ: Roche Pharmaceuticals; August 2006, Accessed for verification September 7, 2008
    • Boniva (ibandronate sodium injection) [package insert]. Nutley, NJ: Roche Pharmaceuticals; August 2006. http://www.fda.gov/MEDWATCH/SAFETY/2007/Feb-PI/ Boniva-Inj-PPI.pdf. Accessed for verification September 7, 2008.
  • 148
    • 38749103949 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw: Balancing the benefits and risks of oral bisphosphonate treatment for osteoporosis [with quiz]
    • Jeffcoat M, Watts NB. Osteonecrosis of the jaw: balancing the benefits and risks of oral bisphosphonate treatment for osteoporosis [with quiz]. Gen Dent. 2008;56: 96-104, 111-112.
    • (2008) Gen Dent , vol.56 , Issue.96-104 , pp. 111-112
    • Jeffcoat, M.1    Watts, N.B.2
  • 149
    • 33746833152 scopus 로고    scopus 로고
    • Primary surgical therapy for osteonecrosis of the jaw secondary to bisphosphonate therapy
    • Kademani D, Koka S, Lacy MQ, Rajkumar SV. Primary surgical therapy for osteonecrosis of the jaw secondary to bisphosphonate therapy. Mayo Clin Proc. 2006;81:1100-1103.
    • (2006) Mayo Clin Proc , vol.81 , pp. 1100-1103
    • Kademani, D.1    Koka, S.2    Lacy, M.Q.3    Rajkumar, S.V.4
  • 150
    • 40449117671 scopus 로고    scopus 로고
    • No osteonecrosis in jaws of young patients with osteogenesis imperfecta treated with bisphosphonates
    • Malmgren B, Aström E, Söderhäll S. No osteonecrosis in jaws of young patients with osteogenesis imperfecta treated with bisphosphonates. J Oral Pathol Med. 2008;37:196-200.
    • (2008) J Oral Pathol Med , vol.37 , pp. 196-200
    • Malmgren, B.1    Aström, E.2    Söderhäll, S.3
  • 151
    • 38849086631 scopus 로고    scopus 로고
    • Bisphosphonate use and the risk of adverse jaw outcomes: A medical claims study of 714,217 people
    • Cartsos VM, Zhu S, Zavras AI. Bisphosphonate use and the risk of adverse jaw outcomes: a medical claims study of 714,217 people. J Am Dent Assoc. 2008;139:23-30.
    • (2008) J Am Dent Assoc , vol.139 , pp. 23-30
    • Cartsos, V.M.1    Zhu, S.2    Zavras, A.I.3
  • 152
    • 38849148975 scopus 로고    scopus 로고
    • Incidence of osteonecrosis of the jaw in women with postmenopausal osteoporosis in the Health Outcomes and Reduced Incidence With Zoledronic Acid Once Yearly Pivotal Fracture Trial
    • Health Outcomes and Reduced Incidence With Zoledronic Acid Once Yearly Pivotal Fracture Trial Research Group
    • Grbic JT, Landesberg R, Lin SQ, et al (Health Outcomes and Reduced Incidence With Zoledronic Acid Once Yearly Pivotal Fracture Trial Research Group). Incidence of osteonecrosis of the jaw in women with postmenopausal osteoporosis in the Health Outcomes and Reduced Incidence With Zoledronic Acid Once Yearly Pivotal Fracture Trial. J Am Dent Assoc. 2008;139:32-40.
    • (2008) J Am Dent Assoc , vol.139 , pp. 32-40
    • Grbic, J.T.1    Landesberg, R.2    Lin, S.Q.3
  • 153
    • 40849085444 scopus 로고    scopus 로고
    • Bisphosphonates and osteonecrosis of the mandible/maxilla in osteoporosis: No reason to panic
    • Bertoldo F. Bisphosphonates and osteonecrosis of the mandible/maxilla in osteoporosis: no reason to panic. Aging Clin Exp Res. 2008;20:87-90.
    • (2008) Aging Clin Exp Res , vol.20 , pp. 87-90
    • Bertoldo, F.1
  • 154
    • 40749111524 scopus 로고    scopus 로고
    • Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: A case-control study
    • Wessel JH, Dodson TB, Zavras AI. Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: a case-control study. J Oral Maxillofac Surg. 2008;66:625-631.
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 625-631
    • Wessel, J.H.1    Dodson, T.B.2    Zavras, A.I.3
  • 156
    • 53449093633 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis
    • Sarasquete ME, García-Sanz R, Marín L, et al. Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Blood. 2008;112: 2709-2712.
    • (2008) Blood , vol.112 , pp. 2709-2712
    • Sarasquete, M.E.1    García-Sanz, R.2    Marín, L.3
  • 157
    • 42149184112 scopus 로고    scopus 로고
    • Inhibition of oral mucosal cell wound healing by bisphosphonates
    • Landesberg R, CozinM, Cremers S, et al. Inhibition of oral mucosal cell wound healing by bisphosphonates. J Oral Maxillofac Surg. 2008;66:839-847.
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 839-847
    • Landesberg, R.1    Cozin, M.2    Cremers, S.3
  • 158
    • 46149121940 scopus 로고    scopus 로고
    • Bisphosphonate-induced osteonecrosis of the jaws: Prospective study of 80 patients with multiple myeloma and other malignancies
    • Boonyapakorn T, Schirmer I, Reichart PA, Sturm I, Massenkeil G. Bisphosphonate-induced osteonecrosis of the jaws: prospective study of 80 patients with multiple myeloma and other malignancies. Oral Oncol. 2008;44: 857-869.
    • (2008) Oral Oncol , vol.44 , pp. 857-869
    • Boonyapakorn, T.1    Schirmer, I.2    Reichart, P.A.3    Sturm, I.4    Massenkeil, G.5
  • 160
    • 53849120955 scopus 로고    scopus 로고
    • Bagan JV, Jiménez Y, Gómez D, Sirera R, Poveda R, Scully C. Collagen telopeptide (serum CTX) and its relationship with the size and number of lesions in osteonecrosis of the jaws in cancer patients on intravenous bisphosphonates [published online ahead of print April 5, 2008]. Oral Oncol.
    • Bagan JV, Jiménez Y, Gómez D, Sirera R, Poveda R, Scully C. Collagen telopeptide (serum CTX) and its relationship with the size and number of lesions in osteonecrosis of the jaws in cancer patients on intravenous bisphosphonates [published online ahead of print April 5, 2008]. Oral Oncol.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.