Fusion protein of Δ27LFn and EFn has the potential as a novel anthrax toxin inhibitor

FEBS Letters

Volumn 583, Issue 8, 2009, Pages 1257-1260

  Kong, Yirong ^a   Guo, Qiang ^a   Yu, Changming ^a   Dong, Dayong ^a   Zhao, Jian ^a   Cai, Chenguang ^a   Hou, Lihua ^a   Song, Xiaohong ^a   Fu, Ling ^a   Xu, Junjie ^a   Chen, Wei ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Anthrax toxin; Fusion protein; PA binding domain of EF; PA binding domain of LF; Toxin inhibitor

Indexed keywords

ANTHRAX EDEMA FACTOR; ANTHRAX LETHAL FACTOR; ANTHRAX TOXIN; ANTITOXIN; CYCLIC AMP; HYBRID PROTEIN; N TERMINAL 27 AMINO ACID DELETION OF ANTHRAX LETHAL FACTOR AND EDEMA FACTOR FUSION PROTEIN; PROTECTIVE ANTIGEN; PROTECTIVE ANTIGEN BINDING DOMAIN OF ANTHRAX EDEMA FACTOR; PROTECTIVE ANTIGEN BINDING DOMAIN OF ANTHRAX LETHAL FACTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; CELL LINE; CELL PROTECTION; CELL VIABILITY; CHO K1 CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENCY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FISCHER 344 RAT; J774A.1 CELL; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROVOCATION TEST; RAT; SURFACE PLASMON RESONANCE; SURVIVAL TIME;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; BASE SEQUENCE; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MALE; RATS; RATS, INBRED F344; RECOMBINANT FUSION PROTEINS;

RATTUS;

EID: 64049098663     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.03.053     Document Type: Article

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