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Volumn 79, Issue 3, 2009, Pages

Kinetics of signaling-DNA-aptamer-ATP binding

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE; APTAMER; ATP BINDINGS; BINDING KINETICS; BINDING REACTIONS; BLOCKING REACTIONS; DNA APTAMERS; DNA MOLECULES; EXPERIMENTAL DATUM; EXPERIMENTAL OBSERVATIONS; FLUORESCENCE QUENCHING; FUNCTIONALIZED; KINETIC MODELS; KINETIC REACTIONS; MODEL PREDICTIONS; MOLECULAR BIOSENSORS; SIDE REACTIONS;

EID: 64049095423     PISSN: 15393755     EISSN: 15502376     Source Type: Journal    
DOI: 10.1103/PhysRevE.79.031906     Document Type: Article
Times cited : (12)

References (32)
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    • R. Nutiu and Y. Li, J. Am. Chem. Soc. 125, 4771 (2003). 10.1021/ja028962o
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    • 4544303933 scopus 로고    scopus 로고
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    • http://www.bioinfo.rpi.edu/applications/mfold/;
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  • 27
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    • When only bimolecular reactions [Eqs. 17 18] were used in order to obtain good fitting to the experiments we needed to put k3 =0.02-0.04× 10-3, 42.7-0.04, 195-0.06, and 0.51-0.14(1/s) for Q10, Q11, Q12, and Q13, respectively. However, as discussed in Sec. 4, k3 should not vary with the length of QDNA because it is not directly related to the reactions between the DNA aptamer and QDNA. Thus, we concluded that bimolecular reactions alone do not provide a consistent description of the experiments.
    • When only bimolecular reactions [Eqs. 17 18] were used in order to obtain good fitting to the experiments we needed to put k3 =0.02-0.04× 10-3, 42.7-0.04, 195-0.06, and 0.51-0.14(1/s) for Q10, Q11, Q12, and Q13, respectively. However, as discussed in Sec. 4, k3 should not vary with the length of QDNA because it is not directly related to the reactions between the DNA aptamer and QDNA. Thus, we concluded that bimolecular reactions alone do not provide a consistent description of the experiments.
  • 29
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    • C. Fradin, private communication.
    • Fradin, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.