-
1
-
-
0035468762
-
-
For reviews, see: a
-
For reviews, see: (a) Zappala, M.; Grasso, S.; Micale, N.; Polimeni, S.; De Micheli, C. Mini-Rev. Med. Chem. 2001, 1, 243-253.
-
(2001)
Mini-Rev. Med. Chem
, vol.1
, pp. 243-253
-
-
Zappala, M.1
Grasso, S.2
Micale, N.3
Polimeni, S.4
De Micheli, C.5
-
3
-
-
84962476695
-
-
For recent examples, see: a
-
For recent examples, see: (a) Zappala, M.; Postorino, G.; Micale, N.; Caccamese, S.; Parrinello, N.; Grazioso, G.; Roda, G.; Menniti, F. S.; De Sarro, G.; Grasso, S. J. Med. Chem. 2006, 49, 575-581.
-
(2006)
J. Med. Chem
, vol.49
, pp. 575-581
-
-
Zappala, M.1
Postorino, G.2
Micale, N.3
Caccamese, S.4
Parrinello, N.5
Grazioso, G.6
Roda, G.7
Menniti, F.S.8
De Sarro, G.9
Grasso, S.10
-
4
-
-
22244493337
-
-
(b) Elger, B.; Huth, A.; Neuhaus, R.; Ottow, E.; Schneider, H.; Seilheimer, B.; Turski, L. J. Med. Chem. 2005, 48, 4618-4627.
-
(2005)
J. Med. Chem
, vol.48
, pp. 4618-4627
-
-
Elger, B.1
Huth, A.2
Neuhaus, R.3
Ottow, E.4
Schneider, H.5
Seilheimer, B.6
Turski, L.7
-
5
-
-
0042231981
-
-
(c) Gitto, R.; Orlando, V.; Quartarone, S.; De Sarro, G.; De Sarro, A.; Russo, E.; Ferreri, G.; Chimirri, A. J. Med. Chem. 2003, 46, 3758-3761.
-
(2003)
J. Med. Chem
, vol.46
, pp. 3758-3761
-
-
Gitto, R.1
Orlando, V.2
Quartarone, S.3
De Sarro, G.4
De Sarro, A.5
Russo, E.6
Ferreri, G.7
Chimirri, A.8
-
6
-
-
0034899184
-
-
(d) Szabados, T.; Gigler, G.; Gacsalyi, I.; Gyertan, I.; Levay, G. Brain Res. Bull. 2001, 55, 387-391.
-
(2001)
Brain Res. Bull
, vol.55
, pp. 387-391
-
-
Szabados, T.1
Gigler, G.2
Gacsalyi, I.3
Gyertan, I.4
Levay, G.5
-
7
-
-
33749530710
-
-
Matsuya, Y.; Ohsawa, N.; Nemoto, H. J. Am. Chem. Soc. 2006, 128, 13072-13073.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 13072-13073
-
-
Matsuya, Y.1
Ohsawa, N.2
Nemoto, H.3
-
8
-
-
0034703294
-
-
Recently, a diazabicyclic benzotropolone framework has been reported; see: For a recent report on the synthesis of monocyclic 2-azatropone, see: a
-
For a recent report on the synthesis of monocyclic 2-azatropone, see: (a) Takami, S.; Oshida, A.; Tawada, Y.; Kashino, S.; Satake, K.; Kimura, M. J. Org. Chem. 2000, 65, 6093-6096. Recently, a diazabicyclic benzotropolone framework has been reported; see:
-
(2000)
J. Org. Chem
, vol.65
, pp. 6093-6096
-
-
Takami, S.1
Oshida, A.2
Tawada, Y.3
Kashino, S.4
Satake, K.5
Kimura, M.6
-
9
-
-
34347383308
-
-
(b) Khrizman, A.; Moulthrop, J. S.; Little, S.; Wharton, H.; Yardley, V.; Moyna, G. Bioorg. Med. Chem. Lett. 2007, 17, 4183-4186.
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 4183-4186
-
-
Khrizman, A.1
Moulthrop, J.S.2
Little, S.3
Wharton, H.4
Yardley, V.5
Moyna, G.6
-
10
-
-
2342509584
-
-
For recent topics on benzotropones, see: a
-
For recent topics on benzotropones, see: (a) Ohkita, M.; Sano, K.; Suzuki, T.; Tsuji, T.; Sato, T.; Niino, H. Org. Biomol. Chem. 2004, 2, 1044-1050.
-
(2004)
Org. Biomol. Chem
, vol.2
, pp. 1044-1050
-
-
Ohkita, M.1
Sano, K.2
Suzuki, T.3
Tsuji, T.4
Sato, T.5
Niino, H.6
-
11
-
-
18744364696
-
-
(b) Güney, M.; Dastan, A.; Balci, M. Helv. Chim. Acta 2005, 88, 830-838.
-
(2005)
Helv. Chim. Acta
, vol.88
, pp. 830-838
-
-
Güney, M.1
Dastan, A.2
Balci, M.3
-
12
-
-
0035829038
-
-
(c) Ohkita, M.; Sano, K.; Suzuki, T.; Tsuji, T. Tetrahedron Lett. 2001, 42, 7295-7297.
-
(2001)
Tetrahedron Lett
, vol.42
, pp. 7295-7297
-
-
Ohkita, M.1
Sano, K.2
Suzuki, T.3
Tsuji, T.4
-
13
-
-
64349102174
-
-
Preparation of these compounds is described in the Supporting Information
-
Preparation of these compounds is described in the Supporting Information.
-
-
-
-
14
-
-
64349088172
-
-
The adduct 6 is likely to be stable only in a solution. Attempts to isolate 6 ended in failure because regeneration of the diazepine 4 took place during the isolation process.
-
The adduct 6 is likely to be stable only in a solution. Attempts to isolate 6 ended in failure because regeneration of the diazepine 4 took place during the isolation process.
-
-
-
-
15
-
-
34250852857
-
-
Recently, decomposition of 1, 2, 3-triazolines with loss of nitrogen to form aziridines has been reported; see: Kim, S.; Lee, Y. M.; Lee, J.; Lee, T.; Fu, Y.; Song, Y.; Cho, J.; Kim, D. J. Org. Chem. 2007, 72, 4886-4891.
-
Recently, decomposition of 1, 2, 3-triazolines with loss of nitrogen to form aziridines has been reported; see: Kim, S.; Lee, Y. M.; Lee, J.; Lee, T.; Fu, Y.; Song, Y.; Cho, J.; Kim, D. J. Org. Chem. 2007, 72, 4886-4891.
-
-
-
-
19
-
-
64349122362
-
-
4 reduction of 4a (see the Supporting Information), did not participate in the nitrogen extrusion reaction under the optimal conditions.
-
4 reduction of 4a (see the Supporting Information), did not participate in the nitrogen extrusion reaction under the optimal conditions.
-
-
-
-
20
-
-
34250630392
-
-
(a) Ahmed, K.; Zhao, Q.-L.; Matsuya, Y.; Yu, D.-Y.; Salunga, T. L.; Nemoto, H.; Kondo, T. Int. J. Hyperthermia 2007, 23, 353-361.
-
(2007)
Int. J. Hyperthermia
, vol.23
, pp. 353-361
-
-
Ahmed, K.1
Zhao, Q.-L.2
Matsuya, Y.3
Yu, D.-Y.4
Salunga, T.L.5
Nemoto, H.6
Kondo, T.7
-
21
-
-
35148877824
-
-
(b) Ahmed, K.; Zhao, Q.-L.; Matsuya, Y.; Yu, D.-Y.; Feril, L. B., Jr; Nemoto, H.; Kondo, T. Chem. Biol. Interact. 2007, 170, 86-99.
-
(2007)
Chem. Biol. Interact
, vol.170
, pp. 86-99
-
-
Ahmed, K.1
Zhao, Q.-L.2
Matsuya, Y.3
Yu, D.-Y.4
Feril Jr, L.B.5
Nemoto, H.6
Kondo, T.7
-
22
-
-
33750059193
-
-
(c) Matsuya, Y.; Kawaguchi, T.; Ishihara, K.; Ahmed, K.; Zhao, Q.-L.; Kondo, T.; Nemoto, H. Org. Lett. 2006, 8, 4609-4612.
-
(2006)
Org. Lett
, vol.8
, pp. 4609-4612
-
-
Matsuya, Y.1
Kawaguchi, T.2
Ishihara, K.3
Ahmed, K.4
Zhao, Q.-L.5
Kondo, T.6
Nemoto, H.7
-
24
-
-
0025043947
-
-
(b) Baker, M. A.; Cerniglia, G. J.; Zaman, A. Anal. Bio Chem. 1990, 190, 360-365.
-
(1990)
Anal. Bio Chem
, vol.190
, pp. 360-365
-
-
Baker, M.A.1
Cerniglia, G.J.2
Zaman, A.3
-
25
-
-
0027946067
-
-
(c) Vandeputte, C.; Guizon, I.; Genestie-Denis, I.; Vannier, B.; Lorenzon, G. Cell Biol. Toxicol. 1994, 10, 415-421.
-
(1994)
Cell Biol. Toxicol
, vol.10
, pp. 415-421
-
-
Vandeputte, C.1
Guizon, I.2
Genestie-Denis, I.3
Vannier, B.4
Lorenzon, G.5
|