Rapid and transient intracellular oxidative stress due to novel macrosphelides trigger apoptosis via Fas/caspase-8-dependent pathway in human lymphoma U937 cells

Chemico-Biological Interactions

Volumn 170, Issue 2, 2007, Pages 86-99

  Ahmed, Kanwal ^a   Zhao, Qing Li ^a   Matsuya, Yuji ^a   Yu, Da Yong ^a   Feril Jr , Loreto B ^b   Nemoto, Hideo ^a   Kondo, Takashi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Fas; Macrosphelides; N Acetyl l cysteine; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 8; CYTOCHROME C; FAS ANTIGEN; GLUTATHIONE; MACROLIDE; MACROSPHELIDE 3; MACROSPHELIDE 5; PROTEIN BID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LYMPHOMA CELL LINE; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS;

ACETYLCYSTEINE; ANTIGENS, CD95; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOTTING, WESTERN; CASPASE 8; CYTOCHROMES C; FLOW CYTOMETRY; GLUTATHIONE; HETEROCYCLIC COMPOUNDS; HUMANS; LIPID PEROXIDATION; MEMBRANE POTENTIALS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; U937 CELLS;

EID: 35148877824     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.07.007     Document Type: Article

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