Synthesis and evaluation of pharmacological properties of novel annelated 2,3-benzodiazepine derivatives

Journal of Medicinal Chemistry

Volumn 46, Issue 17, 2003, Pages 3758-3761

  Gitto, Rosaria ^a   Orlando, Valérie ^a   Quartarone, Silvana ^a   De Sarro, Giovambattista ^b   De Sarro, Angela ^c   Russo, Emilio ^b   Ferreri, Guido ^b   Chimirri, Alba ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b Univ Degli Stud di Reggio Calabria   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 8,9 DIMETHOXY 6 (4 BROMOPHENYL) 1H 1,2,4 TRIAZOLO[4,5 C][2,3]BENZODIAZEPIN 3(2H) ONE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; BENZODIAZEPINE DERIVATIVE; TALAMPANEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN NERVE CELL; DRUG POTENCY; DRUG SYNTHESIS; MEMBRANE CURRENT; MOUSE; NONHUMAN; RAT;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; ANTICONVULSANTS; BENZODIAZEPINES; DISEASE MODELS, ANIMAL; EPILEPSY; EXCITATORY AMINO ACID AGONISTS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED DBA; NEURONS; OLFACTORY PATHWAYS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 0042231981     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030821p     Document Type: Article

References (17)

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