Design and characterization of novel hybrid peptides from LFB15(W4,10), HP(2-20), and cecropin A based on structure parameters by computer-aided method

Applied Microbiology and Biotechnology

Volumn 82, Issue 6, 2009, Pages 1097-1103

  Tian, Zi Gang ^a   Dong, Tian Tang ^a   Teng, Da ^a   Yang, Ya Lin ^a   Wang, Jian Hua ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Antimicrobial peptides; Computer aided method; Design; Structure parameters

Indexed keywords

AMPHIPATHIC; ANTI-MICROBIAL ACTIVITIES; ANTI-MICROBIAL AGENTS; ANTIBIOTIC ACTIVITIES; ANTIBIOTIC RESISTANCES; ANTIMICROBIAL PEPTIDES; BACTERIAL STRAINS; BACTERICIDAL ACTIVITIES; BIOINFORMATICS TOOLS; CATIONIC ANTIMICROBIAL PEPTIDES; CECROPIN; CONCENTRATION OF; HYBRID PEPTIDES; PATHOGENIC BACTERIA; STRUCTURAL PARAMETERS; STRUCTURE PARAMETERS; STRUCTURE-ACTIVITY RELATIONSHIPS;

ANTIBIOTICS; BACTERIA; BACTERIOLOGY; BIOINFORMATICS; COMPUTATIONAL METHODS; MECHANISMS; PEPTIDES; POLYPEPTIDES;

AMINES;

CECROPIN A; HYBRID PROTEIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN HP 2 20; PROTEIN LFB15; PROTEIN LH28; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOINFORMATICS; CHEMICAL COMPOSITION; CHEMICAL PROPERTY; COMPUTER AIDED DESIGN; CONCENTRATION (COMPOSITION); DRUG DEVELOPMENT; MICROBIAL ACTIVITY; PEPTIDE; RODENT;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOINFORMATICS; COMPUTER AIDED DESIGN; COMPUTER ANALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROCYTE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN STRUCTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; DESIGNER DRUGS; DRUG DESIGN; ERYTHROCYTES; FUNGI; MICROBIAL SENSITIVITY TESTS; RABBITS; RECOMBINANT PROTEINS;

BACTERIA (MICROORGANISMS); ORYCTOLAGUS CUNICULUS;

EID: 63949086076     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-008-1839-x     Document Type: Article

References (31)

1. RB Arrighi C Nakamura J Miyake H Hurd JG Burgess 2002 Design and activity of antimicrobial peptides against sporogonic-stage parasites causing murine malarias Antimicrob Agents Chemother 46 2104 2110
2. HG Boman D Wade IA Boman B Wåhlin RB Merrifield 1989 Antibacterial and antimalarial properties of peptides that are cecropin-melittin hybrids FEBS Lett 259 103 106
3. KL Brown RE Hancock 2006 Cationic host defense (antimicrobial) peptides Curr Opin Immunol 18 24 30
4. J Cheng AZ Randall MJ Sweredoski P Baldi 2005 SCRATCH: a protein structure and structural feature prediction server Nucleic Acids Res 33 W72 W76
5. M Dathe T Wieprecht 1999 Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells Biochim Biophys Acta 1462 71 87
6. G Deléage FF Clerc B Roux DC Gautheron 1988 ANTHEPROT: a package for protein sequence analysis using a microcomputer Comput Appl Biosci 4 351 356
7. R Ferre E Badosa L Feliu M Planas E Montesinos E Bardají 2006 Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides Appl Environ Microbiol 72 3302 3308
8. J Fink RB Merrifield A Boman HG Boman 1989 The chemical synthesis of cecropin D and an analog with enhanced antibacterial activity J Biol Chem 264 6260 6267
9. Gasteiger E, Hoogland C, Gattiker A, Duvaud S, Wilkins MR, Appel RD, Bairoch A (2005) Protein identification and analysis tools on the ExPASy server. In: Walker JM (ed) The Proteomics Protocols Handbook. Humana Press, Totowa, pp 571-607
10. A Giangaspero L Sandri A Tossi 2001 Amphipathic alpha helical antimicrobial peptides Eur J Biochem 268 5589 5600
11. HW Huang 2000 Action of antimicrobial peptides: two-state model Biochemistry 39 8347 8352
12. D Hultmark H Steiner T Rasmuson HG Boman 1980 Insect immunity. Purification and properties of three inducible bactericidal proteins from hemolymph of immunized pupae of Hyalophora cecropia Eur J Biochem 106 7 16
13. Y Jin J Hammer M Pate Y Zhang F Zhu E Zmuda J Blazyk 2005 Antimicrobial activities and structures of two linear cationic peptide families with various amphipathic beta-sheet and alpha-helical potentials Antimicrob Agents Chemother 49 4957 4964
14. DG Kneller FE Cohen R Langridge 1990 Improvements in protein secondary structure prediction by an enhanced neural network J Mol Biol 214 171 182
15. DG Lee HN Kim Y Park HK Kim BH Choi CH Choi KS Hahm 2002 Design of novel analogue peptides with potent antibiotic activity based on the antimicrobial peptide, HP (2-20), derived from N-terminus of Helicobacter pylori ribosomal protein L1 Biochim Biophys Acta 1598 185 194
16. KH Lee DG Lee Y Park DI Kang SY Shin KS Hahm Y Kim 2006 Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori Biochem J 394 Pt 1 105 114
17. J Lv L Yin T Liu Y Wang 2007 Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent Bioorg Med Chem Lett 17 1601 1607
18. AK Marr WJ Gooderham RE Hancock 2006 Antibacterial peptides for therapeutic use: obstacles and realistic outlook Curr Opin Pharmacol 5 468 472
19. K Nomura G Ferrat T Nakajima H Darbon T Iwashita G Corzo 2005 Induction of morphological changes in model lipid membranes and the mechanism of membrane disruption by a large scorpion-derived pore-forming peptide Biophys J 89 4067 4080
20. Y Park KS Hahm 2005 Effects of N- and C-terminal truncation of HP (2-20) from Helicobacter pylori ribosomal protein L1 (RPL1) on its anti-microbial activity Biotechnol Lett 27 193 199
21. CB Park HS Kim SC Kim 1998 Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions Biochem Biophys Res Commun 244 253 257
22. K Pütsep CI Brändén HG Boman S Normark 1999 Antibacterial peptide from H pylori. Nature 398 671 672
23. P Rice I Longden A Bleasby 2000 EMBOSS: the European Molecular Biology Open Software Suite Trends Genet 16 276 277
24. MJ Rodríguez-Hernández J Saugar F Docobo-Pérez BG de la Torre ME Pachón-Ibáñez A García-Curiel F Fernández-Cuenca D Andreu L Rivas J Pachón 2006 Studies on the antimicrobial activity of cecropin A-melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii J Antimicrob Chemother 58 95 100
25. JM Saugar MJ Rodríguez-Hernández BG de la Torre ME Pachón-Ibañez M Fernández-Reyes D Andreu J Pachón L Rivas 2006 Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action Antimicrob Agents Chemother 50 1251 1256
26. A Scheller J Oehlke B Wiesner M Dathe E Krause M Beyermann M Melzig M Bienert 1999 Structural requirements for cellular uptake of alpha-helical amphipathic peptides J Pept Sci 5 185 194
27. MB Strøm BE Haug ∅ Rekdal ML Skar W Stensen JS Svendsen 2002 Important structural features of 15-residue lactoferricin derivatives and methods for improvement of antimicrobial activity Biochem Cell Biol 80 65 74
28. ZG Tian D Teng YL Yang J Luo XJ Feng Y Fan F Zhang JH Wang 2007 Multimerization and fusion expression of bovine lactoferricin derivative LfcinB15-W4,10 in Escherichia coli Appl Microbiol Biotechnol 75 117 124
29. A Tossi L Sandri A Giangaspero 2000 Amphipathic, alpha-helical antimicrobial peptides Biopolymers 55 4 30
30. Tossi A, Sandri L, Giangaspero A (2002) New consensus hydrophobicity scale extended to non-proteinogenic amino acids. In: Benedetti E, Pedone C (eds) Peptides 2002: Proceedings of the twenty-seventh European peptide symposium. Edizioni Ziino, Napoli, pp 416-417
31. YZ Wang ZQ Wang ZR Xu 2004 Comparison of antimicrobial activity in vitro of antimicrobial peptides and antibiotics against gram-positive and gram-negative bacteria Chin J Vet Sci 24 270 273