Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway

Journal of Gastroenterology and Hepatology (Australia)

Volumn 24, Issue 4, 2009, Pages 672-680

  Shamshiri, Hosein ^b   Paragomi, Pedram ^b   Paydar, Mehrak Javadi ^b   Moezi, Leila ^b   Bahadori, Moslem ^c   Behfar, Behnaz ^c   Ardalan, Farid A ^c   Dehpour, Ahmad R ^a,b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Colorectal distension; Lithium; Nitric oxide; Nociceptive threshold; Restraint stress induced defecation; Visceral hypersensitivity

Indexed keywords

ACETIC ACID; AMINOGUANIDINE; LITHIUM CARBONATE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DEFECATION; DEFECATION HABIT; DISEASE MODEL; DRUG EFFECT; FECES ANALYSIS; HYPERSENSITIVITY; IMMOBILIZATION STRESS; IRRITABLE COLON; MALE; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; STOMACH PROTECTION; VISCERAL HYPERSENSITIVITY;

EID: 63849335669     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05652.x     Document Type: Article

References (48)

1. Kuiken SD, Klooker TK, Tytgat GN, Lei A, Boeckxstaens GE. Possible role of nitric oxide in visceral hypersensitivity in patients with irritable bowel syndrome. Neurogastroenterol. Motil. 2006 18 : 115 22.
2. Delvaux M. Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome. Gut. 2002 51 (Suppl 1 i67 71.
3. Camilleri M, Heading RC, Thompson WG. Clinical perspectives, mechanisms, diagnosis and management of irritable bowel syndrome. Aliment. Pharmacol. Ther. 2002 16 : 1407 30.
4. Drossman DA. Review article: an integrated approach to the irritable bowel syndrome. Aliment. Pharmacol. Ther. 1999 13 (Suppl 2 3 14.
5. La JH, Kim TW, Sung TS, Kim HJ, Kim JY, Yang IS. Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome. World. J. Gastroenterol 2005 11 : 237 41.
6. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner S. Functional bowel disorders and functional abdominal pain. Gut. 1999 45 (Suppl. 2 II43 7.
7. Crentsil V. Will corticosteroids and other anti-inflammatory agents be effective for diarrhea-predominant irritable bowel syndrome?. Med. Hypotheses 2005 65 : 97 102.
8. Coutinho SV, Urban MO, Gebhart GF. Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia. Pain 1998 78 : 59 69.
9. Coutinho SV, Gebhart GF. A role for spinal nitric oxide in mediating visceral hyperalgesia in the rat. Gastroenterology 1999 116 : 1399 408.
10. Anai H, Ueta Y, Serino R, Nomura M, Nakashima Y, Yamashita H. Activation of hypothalamic neuronal nitric oxide synthase in lithium-induced diabetes insipidus rats. Psychoneuroendocrinology 2001 26 : 109 20.
11. Bagetta G, Rodino P, Paoletti AM, Arabia A, Massoud R, Nistico G. Systemic administration of lithium chloride and tacrine but not kainic acid augments citrulline content of rat brain. Eur. J. Pharmacol. 1995 294 : 341 4.
12. Dehpour AR, Ghafourifar P, Samenian J, Sadeghipour HR, Sadr SS. The effect of lithium on endothelial-dependent relaxation in rat isolated aorta. Gen. Pharmacol. 1995 26 : 1003 7.
13. Dehpour AR, Aghadadashi H, Ghafourifar P et al. Effect of chronic lithium administration on endothelium-dependent relaxation in rat aorta. Clin. Exp. Pharmacol. Physiol. 2000 27 : 55 9.
14. Dehpour AR, Sadr SS, Nouroddini M et al. Comparison of simultaneous administration of lithium with L-NAME or L-arginine on morphine withdrawal syndrome in mice. Hum. Psychopharmacol 2000 15 : 87 93.
15. Homayoun H, Khavandgar S, Namiranian K, Gaskari SA, Dehpour AR. The role of nitric oxide in anticonvulsant and proconvulsant effects of morphine in mice. Epilepsy. Res. 2002 48 : 33 41.
16. Wegener G, Volke V, Bandpey Z, Rosenberg R. Nitric oxide modulates lithium-induced conditioned taste aversion. Behav. Brain. Res. 2001 118 : 195 200.
17. Harvey BH, Carstens ME, Taljaard JJ. Evidence that lithium induces a glutamatergic: nitric oxide-mediated response in rat brain. Neurochem. Res. 1994 19 : 469 74.
18. Paoletti AM, Piccirilli S, Costa N, Rotiroti D, Bagetta G, Nistico G. Systemic administration of N omega-nitro-l-arginine methyl ester and indomethacin reduces the elevation of brain PGE2 content and prevents seizures and hippocampal damage evoked by LiCl and tacrine in rat. Exp. Neurol. 1998 149 : 349 55.
19. Honar H, Riazi K, Homayoun H et al. Lithium inhibits the modulatory effects of morphine on susceptibility to pentylenetetrazole-induced clonic seizure in mice: involvement of a nitric oxide pathway. Brain Res. 2004 1029 : 48 55.
20. Ikonomov OC, Manji HK. Molecular mechanisms underlying mood stabilization in manic-depressive illness: the phenotype challenge. Am. J. Psychiatry 1999 156 : 1506 14.
21. Phiel CJ, Klein PS. Molecular targets of lithium action. Annu. Rev. Pharmacol. Toxicol. 2001 41 : 789 813.
22. Berridge MJ, Irvine RF. Inositol triphosphate, a novel second messenger in cellular signal transduction. Nature (London) 1984 312 : 315 21.
23. Ebstein RP, Hermoni M, Belmaker RH. The effect of lithium on noradrenaline-induced cyclic AMP accumulation in rat brain: inhibition after chronic treatment and absence of supersensitivity. J. Pharmacol. Exp. Ther. 1980 213 : 161 7.
24. Oppenheim G, Ebstein RP, Belmaker RH. Effect of lithium on the physostigmine-induced behavioral syndrome and plasma cyclic GMP. J. Psychiatr. Res. 1979 15 : 133 8.
25. Jepsen PW, Jensen E, Plenge P, Rafaelsen OJ. Peptic ulcer complaints in lithium-treated and non-lithium-treated manic-depressive patients. Acta. Psychiatr. Scand. 1983 67 : 358 60.
26. Wong RK, Boedeker B, Hickey TM, Wilkinson DS, Johnson LF. Lithium chloride: protective and antisecretory properties in rats. Gastroenterology 1984 87 : 362 71.
27. Wong RK, Boedecker B, Maydonovitch CL. Sex differences in gastric mucosal protection after 16,16-dimethyl PGE2 and lithium chloride. Prostaglandins 1986 32 : 555 61.
28. Ushijima I, Mizuki Y, Hara T, Obara N, Minematsu N, Yamada M. Effect of lithium and purinergic compounds on the behavioral and physiological aspects of restraint stress in rats. Pharmacol. Biochem. Behav. 1992 42 : 431 5.
29. Bagetta G, Corasaniti MT, Melino G, Paoletti AM, Finazzi-Agro A, Nistico G. Lithium and tacrine increase the expression of nitric oxide synthase mRNA in the hippocampus of rat. Biochem. Biophys. Res. Commun. 1993 197 : 1132 9.
30. Nejadkey F, Nahavandi A, Dehpour AR, Mani AR. Role of nitric oxide in the gastro-protective effect of lithium. Pathophysiology 2006 13 : 85 9.
31. La JH, Kim TW, Sung TS, Kang JW, Kim HJ, Yang IS. Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. World. J. Gastroenterol. 2003 9 : 2791 5.
32. Jahng JW, Spencer CM, Choi SH, Kim DG, Houpt TA. Nitric oxide is involved in lithium-induced immediate early gene expressions in the adrenal medulla. Eur. J. Pharmacol. 2004 489 : 111 6.
33. Sadeghipour H, Ghasemi M, Nobakht M, Ebrahimi F, Dehpour AR. Effect of chronic lithium administration on endothelium-dependent relaxation of rat corpus cavernosum: the role of nitric oxide and cyclooxygenase pathways. BJU. Int. 2007 99 : 177 82.
34. Bagetta G, Paoletti AM, Leta A et al. Abnormal expression of neuronal nitric oxide synthase triggers limbic seizures and hippocampal damage in rat. Biochem. Biophys. Res. Commun. 2002 291 : 255 60.
35. Feinstein DL. Potentiation of astroglial nitric oxide synthase type-2 expression by lithium chloride. J. Neurochem. 1998 71 : 883 6.
36. Bagetta G, Massoud R, Rodinò P, Federici G, Nisticò G. Systemic administration of lithium chloride and tacrine increases nitric oxide synthase activity in the hippocampus of rats. Eur. J. Pharmacol. 1993 237 : 61 4.
37. Brookes SJ. Classes of enteric nerve cells in the guinea-pig small intestine. Anat. Rec. 2001 262 : 58 70.
38. Kreiss C, Toegel S, Bauer AJ. Alpha2-adrenergic regulation of NO production alters postoperative intestinal smooth muscle dysfunction in rodents. Am. J. Physiol. Gastrointest. Liver. Physiol. 2004 287 : G658 66.
39. Hierholzer C, Kalff JC, Billiar TR, Bauer AJ, Tweardy DJ, Harbrecht BG. Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock. Am. J. Physiol. Gastrointest. Liver. Physiol. 2004 286 : G225 33.
40. Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 1988 336 : 385 8.
41. Fritz E, Hammer J, Schmidt B, Eherer AJ, Hammer HF. Stimulation of the nitric oxide-guanosine 3′, 5′-cyclic monophosphate pathway by sildenafil: effect on rectal muscle tone, distensibility, and perception in health and in irritable bowel syndrome. Am. J. Gastroenterol. 2003 98 : 2253 60.
42. Kuiken SD, Vergeer M, Heisterkamp SH, Tytgat GN, Boeckxstaens GE. Role of nitric oxide in gastric motor and sensory functions in healthy subjects. Gut. 2002 51 : 212 8.
43. Rodella L, Rezzani R, Agostini C et al. Induction of NADPH-diaphorase activity in the rat periaqueductal gray matter after nociceptive visceral stimulation. Brain. Res. 1998 793 : 333 6.
44. Vizzard MA, Erdman SL, de Groat WC. Increased expression of neuronal nitric oxide synthase (NOS) in visceral neurons after nerve injury. J. Neurosci. 1995 15 : 4033 45.
45. Bonaz B. Visceral sensitivity perturbations integration in the brain-gut axis in functional digestive disorders. J. Physiol. Pharmacol. 2003 54 : 27 42.
46. Kumar VL. Spasmogenic effect of lithium carbonate on smooth muscles of guinea-pig ileum. Indian J. Physiol. Pharmacol. 1992 36 : 225.
47. Hori M, Shimizu K, Nakajyo S, Karaki H, Urakawa N. The inhibitory effect of Li+ on contractile elements of intestinal smooth muscle. Jan. J. Pharmacol. 1995 68 : 111 8.
48. Xu JR, Luo JY, Shang L, Kong WM. Effect of change in an inhibitory neurotransmitter of the myenteric plexus on the pathogenetic mechanism of irritable bowel syndrome subgroups in rat models. Chin. J. Dig. Dis. 2006 7 : 89 96.