The integrative function of TRPC channels

Frontiers in Bioscience

Volumn 14, Issue 1, 2009, Pages 45-58

  Kiselyov, Kirill ^a,c   Patterson, Randen L ^b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c 519 Langley Hall   (United States)

Author keywords

Ion channels; Lipids; Review; Transient Receptor Potential; TRPC

Indexed keywords

CALCIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL C;

ANIMAL; DRUG EFFECT; HUMAN; MECHANOTRANSDUCTION; METABOLISM; PHYSIOLOGY; REVIEW;

ANIMALS; CALCIUM; HUMANS; MECHANOTRANSDUCTION, CELLULAR; TRPC CATION CHANNELS;

EID: 63849292300     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3230     Document Type: Article

References (130)

1. Berridge, M. J.: Inositol trisphosphate and calcium signalling. Nature 361, 315-25(1993) (Pubitemid 23041621)
2. Putney, J. W., Jr. and G. S. Bird: The inositol phosphatecalcium signaling system in nonexcitable cells. Endocr Rev 14, 610-31(1993) (Pubitemid 23320389)
3. Dolmetsch, R. E., K. Xu, and R. S. Lewis: Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392, 933-6(1998) (Pubitemid 28232066)
4. Parekh, A. B. and J. W. Putney, Jr.: Store-operated calcium channels. Physiol Rev 85, 757-810(2005) (Pubitemid 40404641)
5. Liu, X., W. Wang, B. B. Singh, T. Lockwich, J. Jadlowiec, B. O'Connell, R. Wellner, M. X. Zhu, and I. S. Ambudkar: Trp1, a candidate protein for the store-operated Ca (2+) influx mechanism in salivary gland cells. J Biol Chem 275, 3403-11(2000) (Pubitemid 30083047)
6. Xu, S. Z. and D. J. Beech: TrpC1 is a membrane-spanning subunit of store-operated Ca (2+) channels in native vascular smooth muscle cells. Circ Res 88, 84-7(2001) (Pubitemid 32064087)
7. Antoniotti, S., D. Lovisolo, A. Fiorio Pla, and L. Munaron: Expression and functional role of bTRPC1 channels in native endothelial cells. FEBS Lett 510, 189-95(2002) (Pubitemid 34093823)
8. Ahmmed, G. U., D. Mehta, S. Vogel, M. Holinstat, B. C. Paria, C. Tiruppathi, and A. B. Malik: Protein kinase Calpha phosphorylates the TRPC1 channel and regulates storeoperated Ca2+ entry in endothelial cells. J Biol Chem 279, 20941-9(2004) (Pubitemid 38656493)
9. Kim, S. J., Y. S. Kim, J. P. Yuan, R. S. Petralia, P. F. Worley, and D. J. Linden: Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature 426, 285-91(2003) (Pubitemid 37463146)
10. Pla, A. F., D. Maric, S. C. Brazer, P. Giacobini, X. Liu, Y. H. Chang, I. S. Ambudkar, and J. L. Barker: Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation. J Neurosci 25, 2687-701(2005) (Pubitemid 40365180)
11. Liu, X., B. B. Singh, and I. S. Ambudkar: TRPC1 is required for functional store-operated Ca2+ channels. Role of acidic amino acid residues in the S5-S6 region. J Biol Chem 278, 11337-43(2003) (Pubitemid 36792691)
12. Wu, X., T. K. Zagranichnaya, G. T. Gurda, E. M. Eves, and M. L. Villereal: A TRPC1/TRPC3-mediated increase in store-operated calcium entry is required for differentiation of H19-7 hippocampal neuronal cells. J Biol Chem 279, 43392-402(2004) (Pubitemid 39390638)
13. Zagranichnaya, T. K., X. Wu, and M. L. Villereal: Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells. J Biol Chem 280, 29559-69(2005) (Pubitemid 41177031)
14. Rao, J. N., O. Platoshyn, V. A. Golovina, L. Liu, T. Zou, B. S. Marasa, D. J. Turner, X. J. Y. J, and J. Y. Wang: TRPC1 functions as a store-operated Ca2+ channel in intestinal epithelial cells and regulates early mucosal restitution after wounding. Am J Physiol Gastrointest Liver Physiol (2005)
15. Wang, G. X. and M. M. Poo: Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones. Nature 434, 898-904(2005) (Pubitemid 40559002)
16. Cai, S., S. Fatherazi, R. B. Presland, C. M. Belton, F. A. Roberts, P. C. Goodwin, M. M. Schubert, and K. T. Izutsu: Evidence that TRPC1 contributes to calciuminduced differentiation of human keratinocytes. Pflugers Arch 452, 43-52(2006)
17. Du, J., S. Sours-Brothers, R. Coleman, M. Ding, S. Graham, D. H. Kong, and R. Ma: Canonical transient receptor potential 1 channel is involved in contractile function of glomerular mesangial cells. J Am Soc Nephrol 18, 1437-45(2007) (Pubitemid 46717510)
18. Rey, O., S. H. Young, R. Papazyan, M. S. Shapiro, and E. Rozengurt: Requirement of the TRPC1 cation channel in the generation of transient Ca2+ oscillations by the calcium-sensing receptor. J Biol Chem 281, 38730-7(2006) (Pubitemid 46042000)
19. Brann, J. H., J. C. Dennis, E. E. Morrison, and D. A. Fadool: Type-specific inositol 1, 4, 5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2. J Neurochem 83, 1452-60(2002) (Pubitemid 35477484)
20. Liman, E. R., D. P. Corey, and C. Dulac: TRP2: a candidate transduction channel for mammalian pheromone sensory signaling. Proc Natl Acad Sci U S A 96, 5791-6(1999) (Pubitemid 29234697)
21. Menco, B. P., V. M. Carr, P. I. Ezeh, E. R. Liman, and M. P. Yankova: Ultrastructural localization of G-proteins and the channel protein TRP2 to microvilli of rat vomeronasal receptor cells. J Comp Neurol 438, 468-89(2001) (Pubitemid 32831311)
22. Stowers, L., T. E. Holy, M. Meister, C. Dulac, and G. Koentges: Loss of sex discrimination and male-male aggression in mice deficient for TRP2. Science 295, 1493-500(2002) (Pubitemid 34173998)
23. Leypold, B. G., C. R. Yu, T. Leinders-Zufall, M. M. Kim, F. Zufall, and R. Axel: Altered sexual and social behaviors in trp2 mutant mice. Proc Natl Acad Sci U S A 99, 6376-81(2002) (Pubitemid 34493319)
24. Jungnickel, M. K., H. Marrero, L. Birnbaumer, J. R. Lemos, and H. M. Florman: Trp2 regulates entry of Ca2+ into mouse sperm triggered by egg ZP3. Nat Cell Biol 3, 499-502(2001) (Pubitemid 32422086)
25. Gailly, P. and M. Colson-Van Schoor: Involvement of trp-2 protein in store-operated influx of calcium in fibroblasts. Cell Calcium 30, 157-65(2001) (Pubitemid 32785530)
26. Yildirim, E. and L. Birnbaumer: TRPC2: molecular biology and functional importance. Handb Exp Pharmacol 53-75 (2007)
27. Vannier, B., M. Peyton, G. Boulay, D. Brown, N. Qin, M. Jiang, X. Zhu, and L. Birnbaumer: Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel. Proc Natl Acad Sci U S A 96, 2060-4(1999) (Pubitemid 29117867)
28. Li, H. S., X. Z. Xu, and C. Montell: Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron 24, 261-73(1999) (Pubitemid 29466164)
29. Ohki, G., T. Miyoshi, M. Murata, K. Ishibashi, M. Imai, and M. Suzuki: A calcium-activated cation current by an alternatively spliced form of Trp3 in the heart. J Biol Chem 275, 39055-60(2000) (Pubitemid 32058919)
30. Sydorenko, V., Y. Shuba, S. Thebault, M. Roudbaraki, G. Lepage, N. Prevarskaya, and R. Skryma: Receptor-coupled, DAG-gated Ca2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells. J Physiol 548, 823-36(2003) (Pubitemid 36603302)
31. Albert, A. P., V. Pucovsky, S. A. Prestwich, and W. A. Large: TRPC3 properties of a native constitutively active Ca2+-permeable cation channel in rabbit ear artery myocytes. J Physiol 571, 361-9(2006)
32. Philipp, S., B. Strauss, D. Hirnet, U. Wissenbach, L. Mery, V. Flockerzi, and M. Hoth: TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes. J Biol Chem 278, 26629-38(2003) (Pubitemid 36876808)
33. Patterson, R. L., D. B. van Rossum, D. L. Ford, K. J. Hurt, S. S. Bae, P. G. Suh, T. Kurosaki, S. H. Snyder, and D. L. Gill: Phospholipase C-gamma is required for agonistinduced Ca2+ entry. Cell 111, 529-41(2002) (Pubitemid 35356558)
34. Santillan, G., C. Baldi, S. Katz, G. Vazquez, and R. Boland: Evidence that TRPC3 is a molecular component of the 1alpha, 25 (OH) 2D3-activated capacitative calcium entry (CCE) in muscle and osteoblast cells. J Steroid Biochem Mol Biol 89-90, 291-5(2004) (Pubitemid 38844298)
35. Santillan, G., S. Katz, G. Vazquez, and R. L. Boland: TRPC3-like protein and vitamin D receptor mediate 1alpha, 25 (OH) 2D3-induced SOC influx in muscle cells. Int J Biochem Cell Biol 36, 1910-8(2004)
36. Reading, S. A., S. Earley, B. J. Waldron, D. G. Welsh, and J. E. Brayden: TRPC3 mediates pyrimidine receptorinduced depolarization of cerebral arteries. Am J Physiol Heart Circ Physiol 288, H2055-61 (2005) (Pubitemid 40604087)
37. Thebault, S., A. Zholos, A. Enfissi, C. Slomianny, E. Dewailly, M. Roudbaraki, J. Parys, and N. Prevarskaya: Receptor-operated Ca (2+) entry mediated by TRPC3/TRPC6 proteins in rat prostate smooth muscle (PS1) cell line. J Cell Physiol (2005)
38. Yip, H., W. Y. Chan, P. C. Leung, H. Y. Kwan, C. Liu, Y. Huang, V. Michel, D. T. Yew, and X. Yao: Expression of TRPC homologs in endothelial cells and smooth muscle layers of human arteries. Histochem Cell Biol 122, 553-61(2004) (Pubitemid 40174592)
39. White, T. A., A. Xue, E. N. Chini, M. Thompson, G. C. Sieck, and M. E. Wylam: Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes. Am J Respir Cell Mol Biol 35, 243-51(2006) (Pubitemid 44175325)
40. Amaral, M. D. and L. Pozzo-Miller: BDNF Induces Calcium Elevations Associated with IBDNF, a Non-Selective Cationic Current Mediated by TRPC Channels. J Neurophysiol (2007)
41. Amaral, M. D. and L. Pozzo-Miller: TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation. J Neurosci 27, 5179-89(2007) (Pubitemid 46741779)
42. Kaznacheyeva, E., L. Glushankova, V. Bugaj, O. Zimina, A. Skopin, V. Alexeenko, L. Tsiokas, I. Bezprozvanny, and G. N. Mozhayeva: Suppression of TRPC3 leads to disappearance of store-operated channels and formation of a new type of store-independent channels in A431 cells. J Biol Chem 282, 23655-62(2007) (Pubitemid 47311968)
43. Philipp, S., C. Trost, J. Warnat, J. Rautmann, N. Himmerkus, G. Schroth, O. Kretz, W. Nastainczyk, A. Cavalie, M. Hoth, and V. Flockerzi: TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells. J Biol Chem 275, 23965-72(2000) (Pubitemid 30624685)
44. Freichel, M., S. H. Suh, A. Pfeifer, U. Schweig, C. Trost, P. Weissgerber, M. Biel, S. Philipp, D. Freise, G. Droogmans, F. Hofmann, V. Flockerzi, and B. Nilius: Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/-mice. Nat Cell Biol 3, 121-7(2001) (Pubitemid 32118364)
45. Tiruppathi, C., M. Freichel, S. M. Vogel, B. C. Paria, D. Mehta, V. Flockerzi, and A. B. Malik: Impairment of storeoperated Ca2+ entry in TRPC4 (-/-) mice interferes with increase in lung microvascular permeability. Circ Res 91, 70-6(2002) (Pubitemid 34778944)
46. Munsch, T., M. Freichel, V. Flockerzi, and H. C. Pape: Contribution of transient receptor potential channels to the control of GABA release from dendrites. Proc Natl Acad Sci U S A 100, 16065-70(2003) (Pubitemid 38021115)
47. Walker, R. L., S. D. Koh, G. P. Sergeant, K. M. Sanders, and B. Horowitz: TRPC4 currents have properties similar to the pacemaker current in interstitial cells of Cajal. Am J Physiol Cell Physiol 283, C1637-45 (2002) (Pubitemid 35340595)
48. Yang, H., S. Mergler, X. Sun, Z. Wang, L. Lu, J. A. Bonanno, U. Pleyer, and P. S. Reinach: TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells. J Biol Chem 280, 32230-7(2005) (Pubitemid 41361830)
49. Wang, X., J. L. Pluznick, P. Wei, B. J. Padanilam, and S. C. Sansom: TRPC4 forms store-operated Ca2+ channels in mouse mesangial cells. Am J Physiol Cell Physiol 287, C357-64 (2004) (Pubitemid 38955226)
50. Lee, K. P., J. Y. Jun, I. Y. Chang, S. H. Suh, I. So, and K. W. Kim: TRPC4 is an essential component of the nonselective cation channel activated by muscarinic stimulation in mouse visceral smooth muscle cells. Mol Cells 20, 435-41(2005)
51. Bezzerides, V. J., I. S. Ramsey, S. Kotecha, A. Greka, and D. E. Clapham: Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol 6, 709-20(2004) (Pubitemid 39144476)
52. Liu, D. Y., F. Thilo, A. Scholze, A. Wittstock, Z. G. Zhao, C. Harteneck, W. Zidek, Z. M. Zhu, and M. Tepel: Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerolinduced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension. J Hypertens 25, 799-808(2007) (Pubitemid 46398875)
53. Wu, G., Z. H. Lu, A. G. Obukhov, M. C. Nowycky, and R. W. Ledeen: Induction of calcium influx through TRPC5 channels by cross-linking of GM1 ganglioside associated with alpha5beta1 integrin initiates neurite outgrowth. J Neurosci 27, 7447-58(2007) (Pubitemid 47066565)
54. Beech, D. J.: Bipolar phospholipid sensing by TRPC5 calcium channel. Biochem Soc Trans 35, 101-4(2007)
55. Xu, S. Z., K. Muraki, F. Zeng, J. Li, P. Sukumar, S. Shah, A. M. Dedman, P. K. Flemming, D. McHugh, J. Naylor, A. Cheong, A. N. Bateson, C. M. Munsch, K. E. Porter, and D. J. Beech: A sphingosine-1-phosphateactivated calcium channel controlling vascular smooth muscle cell motility. Circ Res 98, 1381-9(2006) (Pubitemid 43948062)
56. Albert, A. P. and W. A. Large: Synergism between inositol phosphates and diacylglycerol on native TRPC6-like channels in rabbit portal vein myocytes. J Physiol 552, 789-95(2003) (Pubitemid 37428420)
57. Onohara, N., M. Nishida, R. Inoue, H. Kobayashi, H. Sumimoto, Y. Sato, Y. Mori, T. Nagao, and H. Kurose: TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. Embo J 25, 5305-16(2006) (Pubitemid 44764140)
58. Inoue, R., T. Okada, H. Onoue, Y. Hara, S. Shimizu, S. Naitoh, Y. Ito, and Y. Mori: The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha (1)-adrenoceptor-activated Ca (2+)-permeable cation channel. Circ Res 88, 325-32(2001) (Pubitemid 32173757)
59. Yu, Y., M. Sweeney, S. Zhang, O. Platoshyn, J. Landsberg, A. Rothman, and J. X. Yuan: PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression. Am J Physiol Cell Physiol 284, C316-30 (2003) (Pubitemid 36120070)
60. Thebault, S., A. Zholos, A. Enfissi, C. Slomianny, E. Dewailly, M. Roudbaraki, J. Parys, and N. Prevarskaya: Receptor-operated Ca2+ entry mediated by TRPC3/TRPC6 proteins in rat prostate smooth muscle (PS1) cell line. J Cell Physiol 204, 320-8(2005) (Pubitemid 40778689)
61. Zhang, L., F. Guo, J. Y. Kim, and D. Saffen: Muscarinic acetylcholine receptors activate TRPC6 channels in PC12D cells via Ca2+ store-independent mechanisms. J Biochem (Tokyo) 139, 459-70(2006) (Pubitemid 43667110)
62. Hassock, S. R., M. X. Zhu, C. Trost, V. Flockerzi, and K. S. Authi: Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the storeindependent calcium entry channel. Blood 100, 2801-11(2002)
63. Soboloff, J., M. Spassova, W. Xu, L. P. He, N. Cuesta, and D. L. Gill: Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. J Biol Chem 280, 39786-94(2005) (Pubitemid 41779111)
64. Maruyama, Y., Y. Nakanishi, E. J. Walsh, D. P. Wilson, D. G. Welsh, and W. C. Cole: Heteromultimeric TRPC6-TRPC7 channels contribute to arginine vasopressininduced cation current of A7r5 vascular smooth muscle cells. Circ Res 98, 1520-7(2006) (Pubitemid 44297075)
65. Singh, I., N. Knezevic, G. U. Ahmmed, V. Kini, A. B. Malik, and D. Mehta: Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin. J Biol Chem 282, 7833-43(2007) (Pubitemid 47093600)
66. Carter, R. N., G. Tolhurst, G. Walmsley, M. Vizuete-Forster, N. Miller, and M. P. Mahaut-Smith: Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte. J Physiol 576, 151-62(2006) (Pubitemid 44426227)
67. Yuan, J. P., W. Zeng, G. N. Huang, P. F. Worley, and S. Muallem: STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol 9, 636-45(2007) (Pubitemid 47214725)
68. Worley, P. F., W. Zeng, G. N. Huang, J. P. Yuan, J. Y. Kim, M. G. Lee, and S. Muallem: TRPC channels as STIM1-regulated store-operated channels. Cell Calcium 42, 205-11(2007) (Pubitemid 47029603)
69. Beck, B., A. Zholos, V. Sydorenko, M. Roudbaraki, V. Lehen'kyi, P. Bordat, N. Prevarskaya, and R. Skryma: TRPC7 is a receptor-operated DAG-activated channel in human keratinocytes. J Invest Dermatol 126, 1982-93(2006) (Pubitemid 44255474)
70. Lievremont, J. P., G. S. Bird, and J. W. Putney, Jr.: Canonical transient receptor potential TRPC7 can function as both a receptor-and store-operated channel in HEK-293 cells. Am J Physiol Cell Physiol 287, C1709-16 (2004)
71. Lievremont, J. P., T. Numaga, G. Vazquez, L. Lemonnier, Y. Hara, E. Mori, M. Trebak, S. E. Moss, G. S. Bird, Y. Mori, and J. W. Putney, Jr.: The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. J Biol Chem 280, 35346-51(2005) (Pubitemid 41532723)
72. Vazquez, G., J. P. Lievremont, J. B. G. St, and J. W. Putney, Jr.: Human Trp3 forms both inositol trisphosphate receptor-dependent and receptor-independent storeoperated cation channels in DT40 avian B lymphocytes. Proc Natl Acad Sci U S A 98, 11777-82(2001) (Pubitemid 32928805)
73. Kiselyov, K., A. Soyombo, and S. Muallem: TRPpathies. J Physiol 578, 641-53(2007) (Pubitemid 46165501)
74. Hofmann, T., A. G. Obukhov, M. Schaefer, C. Harteneck, T. Gudermann, and G. Schultz: Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397, 259-63(1999)
75. Venkatachalam, K., H. T. Ma, D. L. Ford, and D. L. Gill: Expression of functional receptor-coupled TRPC3 channels in DT40 triple receptor InsP3 knockout cells. J Biol Chem 276, 33980-5(2001)
76. Trebak, M., J. B. G. St, R. R. McKay, L. Birnbaumer, and J. W. Putney, Jr.: Signaling mechanism for receptoractivated canonical transient receptor potential 3 (TRPC3) channels. J Biol Chem 278, 16244-52(2003) (Pubitemid 36799749)
77. Trebak, M., G. S. Bird, R. R. McKay, and J. W. Putney, Jr.: Comparison of human TRPC3 channels in receptoractivated and store-operated modes. Differential sensitivity to channel blockers suggests fundamental differences in channel composition. J Biol Chem 277, 21617-23(2002) (Pubitemid 34952310)
78. Delmas, P., N. Wanaverbecq, F. C. Abogadie, M. Mistry, and D. A. Brown: Signaling microdomains define the specificity of receptor-mediated InsP (3) pathways in neurons. Neuron 34, 209-20(2002) (Pubitemid 34442564)
79. Martin, A. C. and D. M. Cooper: Capacitative and 1-oleyl-2-acetyl-sn- glycerol-activated Ca (2+) entry distinguished using adenylyl cyclase type 8. Mol Pharmacol 70, 769-77(2006) (Pubitemid 44092337)
80. Villar, A. V., F. M. Goni, and A. Alonso: Diacylglycerol effects on phosphatidylinositol-specific phospholipase C activity and vesicle fusion. FEBS Lett 494, 117-20(2001) (Pubitemid 32289383)
81. Goni, F. M. and A. Alonso: Structure and functional properties of diacylglycerols in membranes. Prog Lipid Res 38, 1-48(1999) (Pubitemid 29090112)
82. Krapivinsky, G., S. Mochida, L. Krapivinsky, S. M. Cibulsky, and D. E. Clapham: The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron 52, 485-96(2006) (Pubitemid 44679819)
83. Spassova, M. A., T. Hewavitharana, W. Xu, J. Soboloff, and D. L. Gill: A common mechanism underlies stretch activation and receptor activation of TRPC6 channels. Proc Natl Acad Sci U S A 103, 16586-91(2006) (Pubitemid 44715239)
84. Dietrich, A., Y. S. M. Mederos, M. Gollasch, V. Gross, U. Storch, G. Dubrovska, M. Obst, E. Yildirim, B. Salanova, H. Kalwa, K. Essin, O. Pinkenburg, F. C. Luft, T. Gudermann, and L. Birnbaumer: Increased vascular smooth muscle contractility in TRPC6-/-mice. Mol Cell Biol 25, 6980-9(2005) (Pubitemid 41105898)
85. Kim, M. T., B. J. Kim, J. H. Lee, S. C. Kwon, D. S. Yeon, D. K. Yang, I. So, and K. W. Kim: Involvement of calmodulin and myosin light chain kinase in the activation of mTRPC5 expressed in HEK cells. Am J Physiol Cell Physiol (2005)
86. Shimizu, S., T. Yoshida, M. Wakamori, M. Ishii, T. Okada, M. Takahashi, M. Seto, K. Sakurada, Y. Kiuchi, and Y. Mori: Ca2+/calmodulin dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells. J Physiol (2005)
87. Zhu, M. H., M. Chae, H. J. Kim, Y. M. Lee, M. J. Kim, N. G. Jin, D. K. Yang, I. So, and K. W. Kim: Desensitization of canonical transient receptor potential channel 5 by protein kinase C. Am J Physiol Cell Physiol 289, C591-600 (2005) (Pubitemid 41192668)
88. Venkatachalam, K., F. Zheng, and D. L. Gill: Control of TRPC and store-operated channels by protein kinase C. Novartis Found Symp 258, 172-85; discussion 185-8, 263-6(2004)
89. Kim, J. Y. and D. Saffen: Activation of M1 muscarinic acetylcholine receptors stimulates the formation of a multiprotein complex centered on TRPC6 channels. J Biol Chem 280, 32035-47(2005) (Pubitemid 41291955)
90. Kwan, H. Y., Y. Huang, and X. Yao: Protein kinase C can inhibit TRPC3 channels indirectly via stimulating protein kinase G. J Cell Physiol 207, 315-21(2006)
91. Kwan, H. Y., Y. Huang, and X. Yao: Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G. Proc Natl Acad Sci U S A 101, 2625-30(2004) (Pubitemid 38269361)
92. Kawasaki, B. T., Y. Liao, and L. Birnbaumer: Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor-and store-operated Ca2+ entry channels. Proc Natl Acad Sci U S A 103, 335-40(2006) (Pubitemid 43122401)
93. Vazquez, G., B. J. Wedel, B. T. Kawasaki, G. S. Bird, and J. W. Putney, Jr.: Obligatory role of Src kinase in the signaling mechanism for TRPC3 cation channels. J Biol Chem 279, 40521-8(2004) (Pubitemid 39287643)
94. Hisatsune, C., Y. Kuroda, K. Nakamura, T. Inoue, T. Nakamura, T. Michikawa, A. Mizutani, and K. Mikoshiba: Regulation of TRPC6 channel activity by tyrosine phosphorylation. J Biol Chem 279, 18887-94(2004) (Pubitemid 38623316)
95. Odell, A. F., J. L. Scott, and D. F. Van Helden: Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4. J Biol Chem 280, 37974-87(2005) (Pubitemid 41642411)
96. Mio, K., T. Ogura, S. Kiyonaka, Y. Hiroaki, Y. Tanimura, Y. Fujiyoshi, Y. Mori, and C. Sato: The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas. J Mol Biol 367, 373-83(2007) (Pubitemid 46295420)
97. Yoshida, T., R. Inoue, T. Morii, N. Takahashi, S. Yamamoto, Y. Hara, M. Tominaga, S. Shimizu, Y. Sato, and Y. Mori: Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat Chem Biol 2, 596-607(2006) (Pubitemid 44610344)
98. Dietrich, A., M. Mederos y Schnitzler, J. Emmel, H. Kalwa, T. Hofmann, and T. Gudermann: N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity. J Biol Chem 278, 47842-52(2003) (Pubitemid 37523232)
99. Topala, C. N., R. J. Bindels, and J. G. Hoenderop: Regulation of the epithelial calcium channel TRPV5 by extracellular factors. Curr Opin Nephrol Hypertens 16, 319-24(2007) (Pubitemid 46944329)
100. Chang, Q., S. Hoefs, A. W. van der Kemp, C. N. Topala, R. J. Bindels, and J. G. Hoenderop: The betaglucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 310, 490-3(2005) (Pubitemid 41507962)
101. Tseng, P. H., H. P. Lin, H. Hu, C. Wang, M. X. Zhu, and C. S. Chen: The canonical transient receptor potential 6 channel as a putative phosphatidylinositol 3, 4, 5-trisphosphate-sensitive calcium entry system. Biochemistry 43, 11701-8(2004) (Pubitemid 39277615)
102. Nilius, B., F. Mahieu, J. Prenen, A. Janssens, G. Owsianik, R. Vennekens, and T. Voets: The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4, 5-biphosphate. Embo J 25, 467-78(2006) (Pubitemid 43237654)
103. Zhang, Z., H. Okawa, Y. Wang, and E. R. Liman: Phosphatidylinositol 4, 5-bisphosphate rescues TRPM4 channels from desensitization. J Biol Chem 280, 39185-92(2005) (Pubitemid 41713870)
104. van Rossum, D. B., R. L. Patterson, S. Sharma, R. K. Barrow, M. Kornberg, D. L. Gill, and S. H. Snyder: Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain. Nature 434, 99-104(2005) (Pubitemid 40349392)
105. Caraveo, G., D. B. van Rossum, R. L. Patterson, S. H. Snyder, and S. Desiderio: Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry. Science 314, 122-5(2006) (Pubitemid 44547755)
106. Wen, W., J. Yan, and M. Zhang: Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3. J Biol Chem 281, 12060-8(2006) (Pubitemid 43855470)
107. Kwon, Y., T. Hofmann, and C. Montell: Integration of phosphoinositide-and calmodulin-mediated regulation of TRPC6. Mol Cell 25, 491-503(2007) (Pubitemid 46274446)
108. Graziani, A., C. Rosker, S. D. Kohlwein, M. X. Zhu, C. Romanin, W. Sattler, K. Groschner, and M. Poteser: Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy. Biochem J 396, 147-55(2006) (Pubitemid 43764506)
109. Kannan, K. B., D. Barlos, and C. J. Hauser: Free cholesterol alters lipid raft structure and function regulating neutrophil Ca2+ entry and respiratory burst: correlations with calcium channel raft trafficking. J Immunol 178, 5253-61(2007) (Pubitemid 46595310)
110. Brakeman, P. R., A. A. Lanahan, R. O'Brien, K. Roche, C. A. Barnes, R. L. Huganir, and P. F. Worley: Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386, 284-8(1997) (Pubitemid 27142514)
111. Fagni, L., P. F. Worley, and F. Ango: Homer as both a scaffold and transduction molecule. Sci STKE 2002, RE8 (2002)
112. Frierson, H. F., Jr., G. W. Ross, F. M. Stewart, S. A. Newman, and M. D. Kelly: Unusual sinonasal small-cell neoplasms following radiotherapy for bilateral retinoblastomas. Am J Surg Pathol 13, 947-54(1989) (Pubitemid 19258505)
113. Xiao, B., J. C. Tu, and P. F. Worley: Homer: a link between neural activity and glutamate receptor function. Curr Opin Neurobiol 10, 370-4(2000) (Pubitemid 30389305)
114. Sala, C., G. Roussignol, J. Meldolesi, and L. Fagni: Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons. J Neurosci 25, 4587-92(2005) (Pubitemid 40629149)
115. Tu, J. C., B. Xiao, J. P. Yuan, A. A. Lanahan, K. Leoffert, M. Li, D. J. Linden, and P. F. Worley: Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron 21, 717-26(1998) (Pubitemid 28498781)
116. Yuan, J. P., K. Kiselyov, D. M. Shin, J. Chen, N. Shcheynikov, S. H. Kang, M. H. Dehoff, M. K. Schwarz, P. H. Seeburg, S. Muallem, and P. F. Worley: Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 114, 777-89(2003) (Pubitemid 37186771)
117. Kim, J. Y., W. Zeng, K. Kiselyov, J. P. Yuan, M. H. Dehoff, K. Mikoshiba, P. F. Worley, and S. Muallem: Homer 1 mediates store-and inositol 1, 4, 5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. J Biol Chem 281, 32540-9(2006) (Pubitemid 46036809)
118. Kiselyov, K., X. Xu, G. Mozhayeva, T. Kuo, I. Pessah, G. Mignery, X. Zhu, L. Birnbaumer, and S. Muallem: Functional interaction between InsP3 receptors and store-operated Htrp3 channels. Nature 396, 478-82(1998) (Pubitemid 28553319)
119. Kiselyov, K., G. A. Mignery, M. X. Zhu, and S. Muallem: The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels. Mol Cell 4, 423-9(1999) (Pubitemid 29499795)
120. Boulay, G., D. M. Brown, N. Qin, M. Jiang, A. Dietrich, M. X. Zhu, Z. Chen, M. Birnbaumer, K. Mikoshiba, and L. Birnbaumer: Modulation of Ca (2+) entry by polypeptides of the inositol 1, 4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca (2+) entry. Proc Natl Acad Sci U S A 96, 14955-60(1999) (Pubitemid 30019746)
121. Peters, C. and A. Mayer: Ca2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion. Nature 396, 575-80(1998) (Pubitemid 28563718)
122. Zhang, Z., J. Tang, S. Tikunova, J. D. Johnson, Z. Chen, N. Qin, A. Dietrich, E. Stefani, L. Birnbaumer, and M. X. Zhu: Activation of Trp3 by inositol 1, 4, 5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain. Proc Natl Acad Sci U S A 98, 3168-73(2001) (Pubitemid 32220817)
123. Tang, J., Y. Lin, Z. Zhang, S. Tikunova, L. Birnbaumer, and M. X. Zhu: Identification of common binding sites for calmodulin and inositol 1, 4, 5-trisphosphate receptors on the carboxyl termini of trp channels. J Biol Chem 276, 21303-10(2001)
124. Wedel, B. J., G. Vazquez, R. R. McKay, J. B. G. St, and J. W. Putney, Jr.: A calmodulin/inositol 1, 4, 5-trisphosphate (IP3) receptor-binding region targets TRPC3 to the plasma membrane in a calmodulin/IP3 receptor-independent process. J Biol Chem 278, 25758-65(2003) (Pubitemid 36835333)
125. Stamboulian, S., M. J. Moutin, S. Treves, N. Pochon, D. Grunwald, F. Zorzato, M. De Waard, M. Ronjat, and C. Arnoult: Junctate, an inositol 1, 4, 5-triphosphate receptor associated protein, is present in rodent sperm and binds TRPC2 and TRPC5 but not TRPC1 channels. Dev Biol 286, 326-37(2005) (Pubitemid 41394066)
126. Treves, S., C. Franzini-Armstrong, L. Moccagatta, C. Arnoult, C. Grasso, A. Schrum, S. Ducreux, M. X. Zhu, K. Mikoshiba, T. Girard, S. Smida-Rezgui, M. Ronjat, and F. Zorzato: Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. J Cell Biol 166, 537-48(2004) (Pubitemid 39097173)
127. Esper, R. J., R. A. Nordaby, J. O. Vilarino, A. Paragano, J. L. Cacharron, and R. A. Machado: Endothelial dysfunction: a comprehensive appraisal. Cardiovasc Diabetol 5, 4(2006)
128. Dietrich, A., H. Kalwa, B. Fuchs, F. Grimminger, N. Weissmann, and T. Gudermann: In vivo TRPC functions in the cardiopulmonary vasculature. Cell Calcium 42, 233-44(2007) (Pubitemid 47029599)
129. Schlossmann, J., R. Feil, and F. Hofmann: Signaling through NO and cGMP-dependent protein kinases. Ann Med 35, 21-7(2003) (Pubitemid 36356870)
130. Huang, G. N., W. Zeng, J. Y. Kim, J. P. Yuan, L. Han, S. Muallem, and P. F. Worley: STIM1 carboxyl-terminus activates native SOC, I (crac) and TRPC1 channels. Nat Cell Biol 8, 1003-10(2006) (Pubitemid 44314732)