Improved lipid profile through liver-specific knockdown of liver X receptor α in KKAy diabetic mice

Journal of Lipid Research

Volumn 50, Issue 1, 2009, Pages 22-31

  Rippman, Joerg F ^a   Schoelch, Corinna ^a   Nolte, Thomas ^a   Pavliska, Heidi ^b   van Marle, André ^b   van Es, Helmuth ^b,c   Prestle, Juergen ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b BioFocus DPI   (United Kingdom)

^c Department of Stem Cell Innovations ^*  (Netherlands)

Author keywords

Adenoviral gene transfer; Gene expression; Hypertriglyceridemia; Nuclear hormone receptor; Short hairpin RNA; Triglycerides

Indexed keywords

ABC TRANSPORTER A1; ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 1; ADENOVIRUS VECTOR; LIPOPROTEIN LIPASE; LIVER X RECEPTOR ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHOENOLPYRUVATE CARBOXYKINASE 1; SHORT HAIRPIN RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; CELL RECEPTOR; DNA BINDING PROTEIN; LIPID; LIVER X RECEPTOR; MESSENGER RNA; RNA; SREBF1 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HYPERTRIGLYCERIDEMIA; LIPID LIVER LEVEL; LIPID METABOLISM; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; TRIACYLGLYCEROL BLOOD LEVEL; VIRAL GENE DELIVERY SYSTEM; ADENOVIRUS; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; LIVER; METABOLISM;

ADENOVIRIDAE; ANIMALS; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DNA-BINDING PROTEINS; HYPERTRIGLYCERIDEMIA; LIPIDS; LIPOPROTEIN LIPASE; LIVER; MICE; MODELS, BIOLOGICAL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA; RNA, MESSENGER; STEAROYL-COA DESATURASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 63449111355     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700571-JLR200     Document Type: Article

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