Acid - base catalysis in the extradiol catechol dioxygenase reaction mechanism: Site-directed mutagenesis of His-115 and His-179 in Escherichia coli 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB)

Biochemistry

Volumn 43, Issue 42, 2004, Pages 13390-13396

  Mendel, Sharon ^a   Arndt, Andrew ^a   Bugg, Timothy D H ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETIC MATERIALS; CATALYSIS; ESCHERICHIA COLI; HYDROLYSIS; PH EFFECTS; REACTION KINETICS;

ACID-BASE RESIDUES; BIOMIMETIC MODEL REACTIONS; CATALYTIC RESIDUES; MUTANTS;

ENZYMES;

ALANINE; CATECHOL DERIVATIVE; GLUTAMINE; HISTIDINE; LACTONE; OXYGENASE; TYROSINE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ANALYSIS; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; PH; PRIORITY JOURNAL; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 6344291632     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048518t     Document Type: Article

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