-
1
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
R. L. Juliano and V. Ling. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 455:152-162 (1976).
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
2
-
-
0041837255
-
Blood-brain barrier efflux transport
-
P. L. Golden and G. M. Pollack. Blood-brain barrier efflux transport. J. Pharm. Sci. 92:1739-1753 (2003).
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 1739-1753
-
-
Golden, P.L.1
Pollack, G.M.2
-
3
-
-
0030738677
-
Multidrug resistance: Molecular mechanisms and clinical relevance
-
V. Ling. Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother. Pharmacol. 40:S3-S8 (1997).
-
(1997)
Cancer Chemother. Pharmacol.
, vol.40
-
-
Ling, V.1
-
4
-
-
0024779132
-
P-glycoprotein: Multidrug-resistance and a superfamily of membrane-associated transport proteins
-
P. F. Juranka, R. L. Zastawny, and V. Ling. P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins. FASEB J. 3:2583-2592 (1989).
-
(1989)
FASEB J.
, vol.3
, pp. 2583-2592
-
-
Juranka, P.F.1
Zastawny, R.L.2
Ling, V.3
-
5
-
-
0030963724
-
Identification of a P-glycoprotein-deficient subpopulation in the CF-1 mouse strain using a restriction fragment length polymorphism
-
D. R. Umbenhauer, G. R. Lankas, T. R. Pippert, L. D. Wise, M. E. Cartwright, S. J. Hall, and C. M. Beare. Identification of a P-glycoprotein-deficient subpopulation in the CF-1 mouse strain using a restriction fragment length polymorphism. Toxicol. Appl. Pharmacol. 146:88-94 (1997).
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.146
, pp. 88-94
-
-
Umbenhauer, D.R.1
Lankas, G.R.2
Pippert, T.R.3
Wise, L.D.4
Cartwright, M.E.5
Hall, S.J.6
Beare, C.M.7
-
6
-
-
0028229150
-
Disruption of the mouse mdr1a p-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased senstivity to drugs
-
A. H. Schinkel, J. J. M. Smit, O. van Tellingen, J. H. Beijnen, E. Wagenaar, L. van Deemter, C. A. Mol, M. A. van der Valk, E. C. Robanus-Maandag, H. P. te Riele, A. J. Berns, and P. Borst. Disruption of the mouse mdr1a p-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased senstivity to drugs. Cell 77:491-502 (1994).
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.10
Berns, A.J.11
Borst, P.12
-
7
-
-
0027842835
-
Classical and novel forms of multidrug resistance and the physiological functions of p-glycoproteins in mammals
-
P. Borst, A. H. Schinkel, J. J. M. Smit, E. Wagenaar, L. van Deemter, A. J. Smith, E. W. H. M. Eijdems, F. Baas, and G. J. R. Zaman. Classical and novel forms of multidrug resistance and the physiological functions of p-glycoproteins in mammals. Phamac. Ther. 60:289-299 (1993).
-
(1993)
Phamac. Ther.
, vol.60
, pp. 289-299
-
-
Borst, P.1
Schinkel, A.H.2
Smit, J.J.M.3
Wagenaar, E.4
Van Deemter, L.5
Smith, A.J.6
Eijdems, E.W.H.M.7
Baas, F.8
Zaman, G.J.R.9
-
8
-
-
0027475860
-
Antagonism of the morphine-induced Straub tail reaction by k-opioid receptor activation in mice
-
M. Narita, T. Suzuki, M. Misawa, and H. Nagase. Antagonism of the morphine-induced Straub tail reaction by k-opioid receptor activation in mice. Psychopharmacology (Berl.) 110:254-256 (1993).
-
(1993)
Psychopharmacology (Berl.)
, vol.110
, pp. 254-256
-
-
Narita, M.1
Suzuki, T.2
Misawa, M.3
Nagase, H.4
-
9
-
-
0031444228
-
Blood-brain disposition and antinociceptive effects of -D-penicillamine2,5-enkephalin in the mouse
-
C. Chen and G. M. Pollack. Blood-brain disposition and antinociceptive effects of -D-penicillamine2,5-enkephalin in the mouse. J. Pharmacol Exp. Ther. 283:1151-1159 (1997).
-
(1997)
J. Pharmacol Exp. Ther.
, vol.283
, pp. 1151-1159
-
-
Chen, C.1
Pollack, G.M.2
-
10
-
-
0035049879
-
The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene
-
T. R. Pippert and D. R. Umbenhauer. The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene. J. Biochem. Mol. Toxicol. 15:83-89 (2001).
-
(2001)
J. Biochem. Mol. Toxicol.
, vol.15
, pp. 83-89
-
-
Pippert, T.R.1
Umbenhauer, D.R.2
-
11
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
A. H. Schinkel, E. Wagenaar, C. A. Mol, and L. van Deemter. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J. Clin, Invest. 97:2517-2524 (1996).
-
(1996)
J. Clin, Invest.
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
Van Deemter, L.4
-
12
-
-
0033833430
-
Increased drug delivery to the brain by P-glycoprotein inhibition
-
A. J. Sadeque, C. Wandel, H. He, S. Shah, and A. J. Wood. Increased drug delivery to the brain by P-glycoprotein inhibition. Clin. Pharmacol. Ther. 68:231-237 (2000).
-
(2000)
Clin. Pharmacol. Ther.
, vol.68
, pp. 231-237
-
-
Sadeque, A.J.1
Wandel, C.2
He, H.3
Shah, S.4
Wood, A.J.5
-
13
-
-
0242288066
-
No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects
-
C. Pauli-Magnus, J. Feiner, C. Brett, E. Lin, and D. L. Kroetz. No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects. Clin. Pharmacol. Ther. 74:487-498 (2003).
-
(2003)
Clin. Pharmacol. Ther.
, vol.74
, pp. 487-498
-
-
Pauli-Magnus, C.1
Feiner, J.2
Brett, C.3
Lin, E.4
Kroetz, D.L.5
-
14
-
-
1242349778
-
Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers
-
C. Skarke, M. Jarrar, H. Schmidt, G. Kauert, M. Langer, and G. Geisslinger, and J. Lotsch. Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers. Pharmacogenetics 13:651-660 (2003).
-
(2003)
Pharmacogenetics
, vol.13
, pp. 651-660
-
-
Skarke, C.1
Jarrar, M.2
Schmidt, H.3
Kauert, G.4
Langer, M.5
Geisslinger, G.6
Lotsch, J.7
-
15
-
-
0030972417
-
P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity
-
G. R. Lankas, M. E. Cartwright, and D. Umbenhauer. P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity. Toxicol. Appl. Pharmacol. 143:357-365 (1997).
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.143
, pp. 357-365
-
-
Lankas, G.R.1
Cartwright, M.E.2
Umbenhauer, D.3
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