Combinatorial synthesis of benztropine libraries and their evaluation as monoamine transporter inhibitors

Organic and Biomolecular Chemistry

Volumn 2, Issue 19, 2004, Pages 2861-2869

  Pedersen, Hanne ^a   Sinning, Steffen ^b   Bülow, Anne ^a   Wiborg, Ove ^b   Falborg, Lise ^b   Bols, Mikael ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BENZTROPINE; COMBINATORIAL SYNTHESIS; METHYLATION; MONOAMINES; RADICAL AZIDONATION;

ALKYLATION; AMINES; BENZENE; MASS SPECTROMETRY; MONOMERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPTIMIZATION; REACTION KINETICS; TRANSPORT PROPERTIES;

SYNTHESIS (CHEMICAL);

BENZATROPINE; DOPAMINE; DOPAMINE TRANSPORTER; DOPAMINE UPTAKE INHIBITOR; DRUG DERIVATIVE; NORADRENALIN; NORADRENALIN TRANSPORTER; SEROTONIN; SEROTONIN TRANSPORTER;

ARTICLE; CELL CULTURE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; HUMAN; SYNTHESIS;

BENZTROPINE; CELL LINE; CELLS, CULTURED; COMBINATORIAL CHEMISTRY TECHNIQUES; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; MOLECULAR STRUCTURE; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 6344258304     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b405768f     Document Type: Article

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